[Prevalence of prenatal exposure to cocaine in a sample of newborns from a university teaching hospital]

Abstract:

:OBJECTIVE: To assess the prevalence of prenatal exposure to cocaine in a sample of newborns using two methods: fluorescence polarization immunoassay and interview with the mother. METHODS: This cross-sectional study was carried out in a university teaching hospital. The population included all live births between March 23, 1999 and June 01, 1999 (n=847). Exposure was determined by a benzoylecgonine-positive meconium specimen and/or by a positive interview with the mother. RESULTS: The prevalence of prenatal exposure to cocaine in this sample was 2.4% (16 cases) according to the interviews, and 3.4% (25 cases) according to the meconium analysis. A rate of 4.6% (34 cases) was found when both methods were associated. CONCLUSIONS: We observed that the meconium test was more effective than the maternal interview for the diagnosis of prenatal exposure to cocaine. The meconium analysis enhanced diagnostic chances by 53.4%, compared to 26% in the case of maternal interview.

journal_name

J Pediatr (Rio J)

journal_title

Jornal de pediatria

authors

Cunha GB,Rotta NT,Silva AR,Dieder AL,Wolf AL,Moser C,Silva FF,Socal MP,Silva PF,Margis R

doi

10.2223/jped.277

keywords:

subject

Has Abstract

pub_date

2001-09-01 00:00:00

pages

369-73

issue

5

eissn

0021-7557

issn

1678-4782

journal_volume

77

pub_type

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