Abstract：
:OBJECTIVE: To determine ASO titer profile by establishing ARF differential diagnoses of other diseases with high levels of ASO antibodies. METHODS: We investigated 78 patients with ARF at onset and follow-up, 22 with isolated chorea at onset, 45 with recurrent oropharyngeal tonsillitis, and 23 with recent flare of juvenile idiopathic arthritis. We tested ASO with automated particle-enhanced immunonephelometric assay (Behring(R)-Germany). The ASO (IU/ml) titers were assessed at the following time intervals: 0-7 days, 1-2 weeks, 2-4 weeks, 1-2 months, 2-4 months, 4-6 months, 6-12 months, 1-2 years, 2-3 years, 3-4 years, and 4-5 years after onset of ARF. RESULTS: ASO titers in patients diagnosed with ARF had a significant increase up to the 2-4-month time interval (P<0.0001). Baseline levels were observed afterwards in patients under regular penicillin prophylaxis. The levels of ASO in ARF were also significantly higher than in patients with isolated chorea, recurrent oropharyngeal infections or juvenile idiopathic arthritis (P=0.0025), when age-matched samples of these groups were compared. The testacute;s sensitivity was 73.3% and the specificity was 57.6%, and it was calculated taking into account the upper limit of normality at 320 IU/ml, as well as the established diagnosis of ARF. The testacute;s specificity and positive predictive value increased with rising or higher titers, being higher with titers above 960 UI/ml. CONCLUSION: This reappraisal of ASO profile in ARF patients indicates a remarkable response during the acute phase, and that points to the extent to which ASO levels may differentiate ARF from other diseases with high levels of ASO antibodies, as coincidental but unrelated streptococcal infection or chronic arthritis flareup.
journal_name
J Pediatr (Rio J)journal_title
Jornal de pediatriaauthors
Machado CS,Ortiz K,Martins Ade L,Martins RS,Machado NCdoi
10.2223/jped.185keywords:
subject
Has Abstractpub_date
2001-03-01 00:00:00pages
105-11issue
2eissn
0021-7557issn
1678-4782journal_volume
77pub_type
杂志文章abstract：:OBJECTIVE: This study is the result of an inquiry into the grandmother's role in the decision as well as the duration of her daughter's choice to breast-feed. METHOD: This project uses a phenomenological theoretical background which leads one to understand breast-feeding based on the view of the grandmother. Thus, thi...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.2223/jped.340
更新日期：1999-11-01 00:00:00
abstract：OBJECTIVE:To evaluate the effect of zinc on the appetite for salt foods in children aged 8 months to 5 years. METHOD:Double-blind, placebo-controlled study. Two groups of 20 children refusing to eat salt foods were followed during 6 months. The children in the first group received zinc chelate 1 mg/kg daily for 3 mont...
journal_title：Jornal de pediatria
pub_type： 临床试验,杂志文章
doi：10.2223/1134
更新日期：2004-01-01 00:00:00
abstract：OBJECTIVE:To verify the concurrent validity and interobserver reliability of the Alberta Infant Motor Scale (AIMS) in premature infants followed-up at the outpatient clinic of Instituto Fernandes Figueira, Fundação Oswaldo Cruz (IFF/Fiocruz), in Rio de Janeiro, Brazil. METHODS:A total of 88 premature infants were enro...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.2223/JPED.1836
更新日期：2008-09-01 00:00:00
abstract：OBJECTIVE:To describe the antimicrobial activity of β-defensin-2 produced in the mammary gland and secreted in human breast milk. METHODS:The peptide production was performed by DNA cloning. β-defensin-2 levels were quantified in 61 colostrum samples and 39 mature milk samples from healthy donors, by an indirect enzym...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.1016/j.jped.2014.05.006
更新日期：2015-01-01 00:00:00
abstract：:The objective of this study is evaluate the pulmonary function in full term newborn infants, comparing classic with non-invasive techniques. We describe the pulmonary function laboratory and software developed at Instituto Fernandes Figueira. We studied 10 healthy full-term newborn infants (birthweight 3.260 g + - 460...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.2223/jped.772
更新日期：1994-05-01 00:00:00
abstract：OBJECTIVES:To evaluate the possible effects of the introduction of the pneumococcal conjugate 10-valent vaccine schedule in the state of Parana on pneumococcal meningitis cases and to assess the distribution of serotypes among cases. METHOD:Cross-sectional study with retrospective data collection of cases of pneumococ...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.1016/j.jped.2014.07.002
更新日期：2015-03-01 00:00:00
abstract：:Phototherapy is a common procedure in the neonatal period. However there is great controversy in the literature about when and at which serum bilirubin levels phototherapy and exchange transfusion should be indicated. The aim of this paper is to review the literature and to suggest guidelines to help pediatricians in ...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.2223/jped.776
更新日期：1995-07-01 00:00:00
abstract：OBJECTIVE:To describe the increased risk of acquiring infectious diseases associated with out-of-home childcare and the effectiveness of measures for the control and prevention of diseases transmission at daycare and preschool education centers. SOURCES:A review of literature in the MEDLINE, LILACS and Cochrane Librar...
journal_title：Jornal de pediatria
pub_type： 杂志文章,评审
doi：10.2223/JPED.1649
更新日期：2007-07-01 00:00:00
abstract：OBJECTIVE:To evaluate the prevalence of intestinal parasitoses in Native Brazilian children from 2 to 9 years old. METHODS:A search for ova and parasites was conducted in the stools of children between 2 to 9 years old living in six indigenous villages located in the Middle and Lower Xingu River, to wit: Pavuru, Moygu...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.2223/JPED.2036
更新日期：2010-11-01 00:00:00
abstract：OBJECTIVE:To investigate risk factors for anemia in infants assisted by public health services. METHODS:In a cross-sectional study carried out in Viçosa, state of Minas Gerais, Brazil, 205 children from 6 to 12 months were evaluated. Socioeconomic, environmental and biological data were collected, as well as informati...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.2223/JPED.1603
更新日期：2007-03-01 00:00:00
abstract：OBJECTIVE:To determine the prevalence of pathologic gastroesophageal reflux in a group of regurgitant infants attended at Helena Moura Hospital, Recife, State of Pernambuco, Brazil. The clinical criteria employed were based on Rome II criteria. METHOD:The study design was transversal. The patients were all children of...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：
更新日期：2004-07-01 00:00:00
abstract：OBJECTIVES:To evaluate the motor performance of premature neonates using the Alberta Infant Motor Scale (AIMS) and to investigate the influence of birth weight on motor acquisition. METHODS:A cross-sectional study was carried out of a prospective cohort of 44 premature newborn infants with gestational ages from 32 to ...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.2223/JPED.1741
更新日期：2008-01-01 00:00:00
abstract：OBJECTIVE:to evaluate changes in the biochemical profile of children treated or being treated for moderate or severe stunting in a nutrition recovery and education center. METHODS:this was a retrospective longitudinal study of 263 children treated at this center between August of 2008 to August of 2011, aged 1 to 6 ye...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.1016/j.jped.2013.12.007
更新日期：2014-07-01 00:00:00
abstract：OBJECTIVE:To review well-known aspects of exogenous surfactant therapy, and to discuss controversial points regarding the current state of research. SOURCES:Review of the literature, using Medline and Cochrane Database Library, in association with the authors' experience in relation to exogenous surfactant replacement...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.2223/jped.900
更新日期：2002-11-01 00:00:00
abstract：:OBJECTIVE: Morbidity and mortality of premature infants have decreased considerably over the last decades, therefore, adequate nutrition of the premature is a major concern. Enteral feeding is the route of choice, but when it is not possible the parenteral route, which contains glucose as one of its main components, i...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.2223/jped.463
更新日期：1998-09-01 00:00:00
abstract：OBJECTIVE:To assess the prevalence of metabolic syndrome-like symptoms in a population of preterm infants with very low birth weight (<1500g) at 2 years of corrected age and identify the occurrence of associated risk factors. METHODS:Cross-sectional study during a five-year period, including preterm infants born with ...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.1016/j.jped.2018.02.009
更新日期：2019-01-01 00:00:00
abstract：OBJECTIVE:To warn pediatricians about the high prevalence of bullying among students, to raise their awareness about the importance of their action in the prevention, diagnosis, and treatment of possible damage to children s health and development, and about the necessity to instruct families and society on how to face...
journal_title：Jornal de pediatria
pub_type： 杂志文章,评审
doi：10.2223/JPED.1403
更新日期：2005-11-01 00:00:00
abstract：:OBJECTIVE: To review the use of corticosteroids in the treatment of newborns with chronic lung disease, adrenal insufficiency and upper airway edema. SOURCES: Review of the available medical literature on the use of corticosteroids in newborns. SUMMARY OF THE FINDINGS: Although there is evidence of short-term clinical...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.2223/jped.216
更新日期：2001-07-01 00:00:00
abstract：OBJECTIVE:The aim of this study was to investigate the effect of different ergonomic desk designs and pencil grip patterns on handwriting performance in children with hemiplegic cerebral palsy and healthy children. METHODS:Twenty-six children with left hemiplegic cerebral palsy and 32 typically developing children wer...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.2223/JPED.1914
更新日期：2009-07-01 00:00:00
abstract：OBJECTIVE:To review the new options in insulin therapy for controlling diabetes mellitus in children and adolescents. SOURCES:Articles indexed in PubMed were located using the search terms insulin analogs in children and adolescents and reviewed. Information was also obtained from American Diabetes Association and Soc...
journal_title：Jornal de pediatria
pub_type： 杂志文章,评审
doi：10.2223/JPED.1712
更新日期：2007-11-01 00:00:00
abstract：OBJECTIVES:The purpose of this study was to investigate what effect the ingestion of sardines, rich in omega-3 series polyunsaturated fatty acids, has on the composition of breastmilk. METHODS:This was a prospective study of 31 nursing mothers under observation at the Hospital Guilherme Alvaro. Each was given 2 kg of ...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.2223/JPED.1439
更新日期：2006-01-01 00:00:00
abstract：OBJECTIVE:To investigate the extent to which sexual orientation-based bullying relates to self-reported feelings of loneliness and sleeping difficulty among Brazilian middle school students. METHOD:This is a cross-sectional study using data from the 2015 PeNSE (Pesquisa Nacional de Saúde do Escolar), a survey designed...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.1016/j.jped.2020.03.005
更新日期：2020-04-15 00:00:00
abstract：OBJECTIVE:To present a new branch of scientific knowledge, known as the developmental origins of health and disease (DOHaD), covering its concepts, study methods and ethical considerations in addition to the prospects for this area of knowledge. SOURCES:A non-systematic review of the biomedical literature intended to ...
journal_title：Jornal de pediatria
pub_type： 杂志文章,评审
doi：10.2223/JPED.1728
更新日期：2007-11-01 00:00:00
abstract：:OBJECTIVE: Evaluation of epidemiological, clinical and laboratory features of Plasmodium vivax malaria in children and adolescents. METHODS: This study was carried out in the Malaria Program of the Evandro Chagas Institute (Belém, Pará), from January 1995 to November 1996. 100 children and adolescents with the diagnos...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.2223/jped.295
更新日期：1999-05-01 00:00:00
abstract：OBJECTIVE:To review current models and scientific evidence on the influence of parents' oral health behaviors on their children's dental caries. SOURCES:MEDLINE articles published between 1980 and June, 2012. Original research articles on parents' oral health behavior were reviewed. A total of 218 citations were retri...
journal_title：Jornal de pediatria
pub_type： 杂志文章,评审
doi：10.1016/j.jped.2013.03.014
更新日期：2013-03-01 00:00:00
abstract：OBJECTIVE:Report the incidence, epidemiology, clinical features, death, and vaccination status of patients with whooping cough and perform genotypic characterization of isolates of B. pertussis identified in the state of Paraná, during January 2007 to December 2013. METHODS:Cross-sectional study including 1,209 patien...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.1016/j.jped.2014.09.004
更新日期：2015-07-01 00:00:00
abstract：OBJECTIVE:to evaluate neonatal sepsis as a risk factor for abnormal neuromotor and cognitive development in very low birth weight preterm infants at 12 months of corrected age. METHODS:this was a prospective cohort study that followed the neuromotor and cognitive development of 194 very low birth weight preterm infant...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.1016/j.jped.2013.09.006
更新日期：2014-05-01 00:00:00
abstract：OBJECTIVE:This study reviews clinical features, evolution, comorbidity and suicidal behavior in childhood and adolescence depression. Its objective is to provide clear information on this common, severe and not very easily recognized pathology. SOURCES:Literature searches were performed through Medline (1991-2000), wi...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：
更新日期：2002-09-01 00:00:00
abstract：OBJECTIVE:Children's differences in moderate-to-vigorous physical activity levels are not at random. This study investigates the relevance of individual- and school-level characteristics in explaining these differences. METHODS:In total, 307 children (154 girls) aged 5-10 years, from 19 Portuguese schools, were sample...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.1016/j.jped.2018.10.013
更新日期：2020-01-01 00:00:00
abstract：OBJECTIVE:The objective of this review of genetic counseling (GC) is to describe the current concepts and philosophical and ethical principles accepted by the great majority of countries and recommended by the World Health Organization, the stages of the process, its results and the psychological impact that a genetic ...
journal_title：Jornal de pediatria
pub_type： 杂志文章,评审
doi：10.2223/JPED.1782
更新日期：2008-08-01 00:00:00
