Abstract：
OBJECTIVE:To analyze acute splenic sequestration (ASS) in children with sickle cell anemia diagnosed through a newborn screening program in the state of Minas Gerais, Brazil, and followed up at the hematology center in the city of Belo Horizonte, Minas Gerais, Brazil. METHODS:Retrospective cohort of 255 children with sickle cell anemia (Hb SS/Sbeta(0)) born between January 01, 2000, and December 31, 2004, and followed up until December 31, 2006. Data were abstracted from the patients' medical records. RESULTS:A total of 89 patients had 173 episodes of ASS (10.2 first episodes per 100 patient-years); 75% of the first episodes occurred before 2 years of age. The estimated probability of occurrence of the first episode of ASS during the study period was 40%. Recurrence rate reached 57.3%. After the first episode, splenectomy was indicated in only 12.4% of the cases; after the second, in 60.4% of the cases. After the third episode, 41.7% of the patients remained under clinical observation. The median time between indication for splenectomy and the actual surgical procedure was 2 months. During the intervening period, 37.2% of the children suffered a new episode of ASS and one child died. Case-fatality rate was 1.1% for the first episode and 7.8% for the subsequent episodes. Among a total of 255 children, 19 died: 36.8% due to infections and 26.3% after ASS. CONCLUSIONS:ASS is relatively common in sickle cell anemia, mainly in the first 2 years of life; relapse occurs in more than half of the cases. Conservative management instead of immediate splenectomy was the method of choice. Although the case-fatality rate was low, ASS was the second most common cause of death. These results disclose some fragilities of the health system in the state of Minas Gerais and the need for better professional education to approach ASS crises.
journal_name
J Pediatr (Rio J)journal_title
Jornal de pediatriaauthors
Rezende PV,Viana MB,Murao M,Chaves AC,Ribeiro ACdoi
10.2223/JPED.1885subject
Has Abstractpub_date
2009-03-01 00:00:00pages
163-9issue
2eissn
0021-7557issn
1678-4782journal_volume
85pub_type
杂志文章abstract：OBJECTIVE:To evaluate the age at menarche of girls, with or without weight excess, attending private and public schools in a city in Southeastern Brazil. METHODS:This was a cross-sectional study comparing the age at menarche of 750 girls from private schools with 921 students from public schools, aged between 7 and 18...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.1016/j.jped.2014.05.008
更新日期：2015-01-01 00:00:00
abstract：OBJECTIVE:To present an updated review of the most common upper respiratory infections (URI) in children seen by the pediatrician in outpatient clinics, for better diagnostic and therapeutic decisions. SOURCES:References from Medline database were reviewed. The most relevant articles were selected. SUMMARY OF THE FIN...
journal_title：Jornal de pediatria
pub_type： 杂志文章,评审
doi：10.2223/jped.1002
更新日期：2003-05-01 00:00:00
abstract：OBJECTIVE:To analyze the sociodemographic, school, and family factors associated with the patterns of binge drinking and frequent or heavy drinking among adolescents. METHODS:This was a cross-sectional study, nested in a randomized controlled trial, of 6285 seventh and eighth grade adolescent students from Brazilian p...
journal_title：Jornal de pediatria
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.jped.2018.08.005
更新日期：2020-01-01 00:00:00
abstract：:The purpose of the authors in this article was to evaluate the effects of supplementing maternal milk with two different caloric formulas on the growth of premature newborns until they reached 40 weeks of post-conceptional age. Seventy premature infants weighing < 1750g at birth were randomized: 35 adequate for gestat...
journal_title：Jornal de pediatria
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.2223/jped.607
更新日期：1996-05-01 00:00:00
abstract：:In order to better understand the natural history of chronic functional constipation, a questionnaire was applied to 163 children and infants, before beginning standardized treatment. Median age (range) at start was 3 mo(0-108 mo) but age at arrival at the Pediatric Gastroenterology Unit was 53 mo(2-146 mo). In 62.4% ...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.2223/jped.688
更新日期：1994-09-01 00:00:00
abstract：OBJECTIVE:Using a wide and representative sample of adolescents from 37 countries, this study aimed to analyze how age changes adolescents' healthy lifestyle. METHODS:The study included 148,839 adolescents who participated in the Health Behavior in School-aged Children 2010 survey. A composite score of a healthy lifes...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.1016/j.jped.2018.09.002
更新日期：2020-01-01 00:00:00
abstract：OBJECTIVE:To describe the increased risk of acquiring infectious diseases associated with out-of-home childcare and the effectiveness of measures for the control and prevention of diseases transmission at daycare and preschool education centers. SOURCES:A review of literature in the MEDLINE, LILACS and Cochrane Librar...
journal_title：Jornal de pediatria
pub_type： 杂志文章,评审
doi：10.2223/JPED.1649
更新日期：2007-07-01 00:00:00
abstract：OBJECTIVES:To evaluate the motor performance of premature neonates using the Alberta Infant Motor Scale (AIMS) and to investigate the influence of birth weight on motor acquisition. METHODS:A cross-sectional study was carried out of a prospective cohort of 44 premature newborn infants with gestational ages from 32 to ...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.2223/JPED.1741
更新日期：2008-01-01 00:00:00
abstract：OBJECTIVE:To compare the effect of soy polysaccharide on fecal weight and humidity in growing rats in relation to cellulose and a Soy formula without dietary fiber. METHODS:Twelve, 21-day-old, Wistar male rats, were distributed into three groups and fed AIN-93G ration with varying amounts of dietary fiber: Polysacchar...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：
更新日期：2004-05-01 00:00:00
abstract：OBJECTIVE:To report a case of an infant with endstage renal failure caused by primary hyperoxaluria. METHODS:The review of the literature showed the rarity of the disease. In France, the prevalence is about 1.05/million and the incidence rate is 0.12/million/year. A survey, performed in international specialized cente...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：
更新日期：2002-03-01 00:00:00
abstract：OBJECTIVE:To investigate the extent to which sexual orientation-based bullying relates to self-reported feelings of loneliness and sleeping difficulty among Brazilian middle school students. METHOD:This is a cross-sectional study using data from the 2015 PeNSE (Pesquisa Nacional de Saúde do Escolar), a survey designed...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.1016/j.jped.2020.03.005
更新日期：2020-04-15 00:00:00
abstract：OBJECTIVE:to determine the frequency, complications and seasonality at which respiratory syncytial virus (RSV) infection of the lower respiratory tract causes hospitalization in infants of age 1 year or less in 6 cities of Colombia. METHODS:one-year prospective multicentric observational study that included 717 patien...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.1016/j.jped.2013.04.002
更新日期：2013-11-01 00:00:00
abstract：OBJECTIVE:Streptococcus pneumoniae usually colonizes the oropharynx of healthy people. Oropharyngeal carriage is related to the invasion of adjacent structures and to the development of invasive disease. A descriptive cross-sectional study was performed aiming at verifying the prevalence of oropharyngeal colonization b...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：
更新日期：2003-05-01 00:00:00
abstract：:OBJECTIVE: To review current information about congenital and perinatal infections, mainly related to their epidemiology in Brazil, mother-to-infant transmission, diagnosis, treatment and prevention. Particular aspects related to the agents T. pallidum, hepatitis B virus, human immunodeficiency virus, cytomegalovirus ...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.2223/jped.368
更新日期：1999-07-01 00:00:00
abstract：OBJECTIVE:To investigate the immune response of preterm infants to hepatitis B vaccination. METHODS:Three doses of recombinant hepatitis B vaccine (5 micro g dose) were administered to 35 preterm and 21 full-term infants within 24 hours after birth and at one and six months of postnatal age. RESULTS:A protective anti...
journal_title：Jornal de pediatria
pub_type： 临床试验,杂志文章
doi：
更新日期：2004-03-01 00:00:00
abstract：OBJECTIVE:Sedation is an important step in the management of patients with hypercyanotic spells associated with tetralogy of Fallot (TOF) to ameliorate and prevent recurrence of cyanosis. This case report illustrates the effectiveness of dexmedetomidine-induced sedation in the management of hypercyanotic spells in a ne...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.2223/JPED.1794
更新日期：2008-07-01 00:00:00
abstract：OBJECTIVE:To compare the effectiveness of salbutamol administration by metered-dose inhaler with a home-made spacer versus jet nebulizer in children with moderate wheezing attacks. MATERIAL AND METHODS:A randomized, single-blinded trial was performed with a convenience sample of children presenting wheezing. The child...
journal_title：Jornal de pediatria
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：2003-09-01 00:00:00
abstract：OBJECTIVE:To measure the main risk factors associated with the occurrence of accidental injuries in children aged 4-5 years. METHODS:The study included a prospective cohort of children whose parents filled in a diary recording accidents and injuries during a period of one-month. The children represented a systematic s...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：
更新日期：2002-03-01 00:00:00
abstract：OBJECTIVES:The purpose of this study was to investigate what effect the ingestion of sardines, rich in omega-3 series polyunsaturated fatty acids, has on the composition of breastmilk. METHODS:This was a prospective study of 31 nursing mothers under observation at the Hospital Guilherme Alvaro. Each was given 2 kg of ...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.2223/JPED.1439
更新日期：2006-01-01 00:00:00
abstract：:The acute inflammatory demyelinating polyneuropathy (Guillain-Barré Syndrome) might have a severe presentation but a good prognosis in children. It is an immune-mediated and inflammatory disorder of the peripheral nervous system. This retrospective study observed that GBS is frequently complicated by hypertension and ...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.2223/jped.579
更新日期：1996-01-01 00:00:00
abstract：OBJECTIVE:To evaluate the incidence of diarrheal disease (DD) and acute respiratory infection (ARI) in children undergoing supplementation of zinc and other micronutrients through the use of sprinkles, as well as their acceptance by these patients. METHOD:This was a randomized double-blinded clinical trial of 143 heal...
journal_title：Jornal de pediatria
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.jped.2012.11.004
更新日期：2013-05-01 00:00:00
abstract：OBJECTIVE:To report the results of open challenge tests performed in children fed with cow's milk-free diet. DESCRIPTION:Cross-sectional study evaluating cow's milk open challenge performed under supervision in a hospital setting during 2.5 hours and ambulatory follow-up for 30 days when no immediate reaction occurred...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.2223/JPED.1967
更新日期：2010-03-01 00:00:00
abstract：OBJECTIVE:this study aimed to investigate the incidence of premature rupture of fetal membranes in preterm singleton pregnancies and its association with sociodemographic factors and maternal self-reported genitourinary infections. METHODS:this was a population-based cross-sectional study, which included all mothers o...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.1016/j.jped.2013.08.003
更新日期：2014-03-01 00:00:00
abstract：OBJECTIVE:To describe the characteristics of macrophage activation syndrome associated with juvenile idiopathic arthritis. DESCRIPTION:This is a retrospective study involving 462 patients with juvenile idiopathic arthritis. Seven (1.5%) of those patients suffered from systemic onset juvenile idiopathic arthritis and d...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：
更新日期：2004-11-01 00:00:00
abstract：:OBJECTIVE: This study aimed to determine the prevalence of recurrent episodes of pneumonia in patients referred to the pulmonology outpatient unit at "Serviço de Pneumologia Pediatrica" of the Instituto de Puericultura e Pediatria Martagão Gesteira/UFRJ and to review the recurrent concept in accordance to medical refe...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.2223/jped.32
更新日期：2000-01-01 00:00:00
abstract：OBJECTIVE:To identify risk factors for neonatal mortality, focusing on factors related to assistance care during the prenatal period, childbirth, and maternal reproductive history. METHODS:This was a case-control study conducted in Maceió, Northeastern Brazil. The sample consisted of 136 cases and 272 controls selecte...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.1016/j.jped.2012.11.005
更新日期：2013-05-01 00:00:00
abstract：OBJECTIVES:To determine if the number of involved anatomic areas can modify the standard risk groups in pediatric Hodgkin's lymphoma, identifying children who would benefit from a reduction in treatment intensity. METHODS:Retrospective study evaluating age, sex, histology, Ann-Arbor stage, presence of B symptoms, numb...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.2223/JPED.1891
更新日期：2009-05-01 00:00:00
abstract：OBJECTIVE:To measure the prevalence of children with adequate weight who feel fat and to examine the factors associated with this perception. METHODS:Cross-sectional study with 901 schoolchildren aged 8-11 years selected by cluster sampling. The children had their weight and height measured, and answered a questionnai...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.2223/JPED.1477
更新日期：2006-05-01 00:00:00
abstract：:OBJECTIVE: To review and discuss different contraceptive methods currently used by adolescents, and also discuss adolescent pregnancy, including the associated risks and the importance of prenatal care. METHODS: Review of literature and clinical experience with different contraceptive methods and with adolescent pregn...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.2223/jped.305
更新日期：2001-11-01 00:00:00
abstract：:OBJECTIVE: Aiming a better understanding of the distribution of enteropathogens in Brazil, we have investigated the prevalence of enteropathogens in acute infantile diarrhea in children of low economic level from São José do Rio Preto, SP.METHODS: A prospective study with 196 children under age five, all with diarrhea...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.2223/jped.444
更新日期：1998-07-01 00:00:00
