Abstract:
OBJECTIVE:To describe the characteristics of macrophage activation syndrome associated with juvenile idiopathic arthritis. DESCRIPTION:This is a retrospective study involving 462 patients with juvenile idiopathic arthritis. Seven (1.5%) of those patients suffered from systemic onset juvenile idiopathic arthritis and developed macrophage activation syndrome. The median age of the juvenile idiopathic arthritis onset was 3 years and 10 months and the median duration of juvenile idiopathic arthritis before macrophage activation syndrome was 8 years and 4 months. All of them presented with fever, jaundice, hepatosplenomegaly, bleeding, pancytopenia, abnormal liver function tests and abnormal coagulation profile. Three cases presented associated infections and one patient developed macrophage activation syndrome two weeks after the administration of sulfasalazine. Three patients died and the macrophage hemophagocytosis was present in five. The treatment of macrophage activation syndrome included pulse therapy with methylprednisolone in all of them, cyclosporine A in three, plasma exchange in two and intravenous immunoglobulin in two. COMMENTS:Macrophage activation syndrome is a complication of the systemic onset juvenile idiopathic arthritis with a high morbidity and mortality rate.
journal_name
J Pediatr (Rio J)journal_title
Jornal de pediatriaauthors
Silva CA,Silva CH,Robazzi TC,Lotito AP,Mendroni Junior A,Jacob CM,Kiss MHkeywords:
subject
Has Abstractpub_date
2004-11-01 00:00:00pages
517-22issue
6eissn
0021-7557issn
1678-4782journal_volume
80pub_type
杂志文章abstract:OBJECTIVE:To investigate risk factors for anemia in infants assisted by public health services. METHODS:In a cross-sectional study carried out in Viçosa, state of Minas Gerais, Brazil, 205 children from 6 to 12 months were evaluated. Socioeconomic, environmental and biological data were collected, as well as informati...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.2223/JPED.1603
更新日期:2007-03-01 00:00:00
abstract:OBJECTIVES:The purpose of this study was to investigate what effect the ingestion of sardines, rich in omega-3 series polyunsaturated fatty acids, has on the composition of breastmilk. METHODS:This was a prospective study of 31 nursing mothers under observation at the Hospital Guilherme Alvaro. Each was given 2 kg of ...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.2223/JPED.1439
更新日期:2006-01-01 00:00:00
abstract:OBJECTIVE:Exposure to sunlight in childhood is often more intense than in adults. Literature data unequivocally show the association between this social behavior and the risk for developing malignant melanoma and non-melanoma skin cancer, even in adulthood. Furthermore, skin photoaging begins already in childhood throu...
journal_title:Jornal de pediatria
pub_type: 杂志文章,评审
doi:10.2223/jped.2194
更新日期:2012-05-01 00:00:00
abstract:OBJECTIVE:To compare the use of intravenous vs. oral antibiotic therapy. METHODS:All febrile neutropenic patients younger than 18 years old with low risk of complications and receiving chemotherapy were selected. The study was conducted from 2002 to 2005 at the Pediatric Oncology Unit of Hospital de Clínicas de Porto ...
journal_title:Jornal de pediatria
pub_type: 杂志文章,随机对照试验
doi:10.2223/JPED.1956
更新日期:2009-11-01 00:00:00
abstract:OBJECTIVE:Interleukin 8 protein promotes inflammatory responses, even in airways. The presence of interleukin 8 gene variants causes altered inflammatory responses and possibly varied responses to inhaled bronchodilators. Thus, this study analyzed the interleukin 8 variants (rs4073, rs2227306, and rs2227307) and their ...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.1016/j.jped.2017.03.005
更新日期:2017-01-01 00:00:00
abstract:OBJECTIVE:To describe intubation procedures in two pediatric and two neonatal intensive care units in the city of Porto Alegre. METHODS:Cross-sectional study divided into a retrospective and a prospective phase. All intubations performed in these units during a 6-month period were considered. Data were collected by in...
journal_title:Jornal de pediatria
pub_type: 杂志文章,多中心研究
doi:
更新日期:2004-09-01 00:00:00
abstract:OBJECTIVE:Meningococcal disease continues to be a serious public health concern, being associated with high morbidity and mortality rates worldwide, particularly in Brazil. In addition to discussing recent changes in the global epidemiology of meningococcal disease, we also analyze the development and impact of new con...
journal_title:Jornal de pediatria
pub_type: 杂志文章,评审
doi:10.2223/JPED.1495
更新日期:2006-07-01 00:00:00
abstract:OBJECTIVE:Duchenne muscular dystrophy, an X-linked genetic disease, leads to progressive muscle weakness mainly in the lower limbs. Motor function tests help to monitor disease progression. Can low-cost, simple assessments help in the diagnostic suspicion of Duchenne muscular dystrophy? The authors aim to define the se...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.1016/j.jped.2019.02.003
更新日期:2020-01-01 00:00:00
abstract:OBJECTIVES:To identify and characterize respiratory viruses that infect children from daycare centers with symptoms of respiratory infection and to evaluate the association of clinical and epidemiological disease data with the identified virus. METHODS:We conducted a study between 2003 and 2005 in 176 children with re...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.2223/JPED.2126
更新日期:2011-09-01 00:00:00
abstract:OBJECTIVE:this study aimed to investigate the incidence of premature rupture of fetal membranes in preterm singleton pregnancies and its association with sociodemographic factors and maternal self-reported genitourinary infections. METHODS:this was a population-based cross-sectional study, which included all mothers o...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.1016/j.jped.2013.08.003
更新日期:2014-03-01 00:00:00
abstract::BCG-test reaction was carried out in 91 non-tuberculous children between 2 and 11 years old, who had received BCG vaccination during the first six months of life to critically evaluate the usefulness of this test in Pediatric practice. The BCG-test profile of the vaccinated group was shown to have a unimodal distribut...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.2223/jped.678
更新日期:1994-11-01 00:00:00
abstract::OBJECTIVE: This study is the result of an inquiry into the grandmother's role in the decision as well as the duration of her daughter's choice to breast-feed. METHOD: This project uses a phenomenological theoretical background which leads one to understand breast-feeding based on the view of the grandmother. Thus, thi...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.2223/jped.340
更新日期:1999-11-01 00:00:00
abstract:OBJECTIVE:To determine the prevalence of pathologic gastroesophageal reflux in a group of regurgitant infants attended at Helena Moura Hospital, Recife, State of Pernambuco, Brazil. The clinical criteria employed were based on Rome II criteria. METHOD:The study design was transversal. The patients were all children of...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:
更新日期:2004-07-01 00:00:00
abstract::OBJECTIVE: Describe the hemodynamic response with rebound of pulmonary hypertension after withdrawal of inhaled nitric oxide (NO) in a pediatric patient with acute respiratory distress syndrome (ARDS). METHODS: Case report of a child with ARDS and pulmonary hypertension evaluated through ecocardiografic with dopller, ...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.2223/jped.59
更新日期:2000-03-01 00:00:00
abstract:OBJECTIVE:to assess the epidemiological and genetic factors associated with severity of acute viral bronchiolitis (AVB) by respiratory syncytial virus (RSV). DATA SOURCE:the key words "bronchiolitis", "risk factor", "genetics" and "respiratory syncytial virus", and all combinations among them were used to perform a se...
journal_title:Jornal de pediatria
pub_type: 杂志文章,评审
doi:10.1016/j.jped.2013.02.022
更新日期:2013-11-01 00:00:00
abstract::OBJECTIVE: To make a brief review about mechanical ventilation in Pediatrics.METHODS: Review of the classification of types of mechanical ventilation, characteristics of pression and flow waves and indications for its installation. In a sequential way we discuss the various modes of ventilation (control ventilation, a...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.2223/jped.476
更新日期:1998-07-01 00:00:00
abstract:OBJECTIVE:To analyze the quality of life of children with stomas according to the children and mothers' point of view; to compare the results related to quality of life in both groups, and to verify the statistical associations between those aspects and children's demographic and clinical data. METHODS:After fulfillin...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:
更新日期:2003-01-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to investigate the effect of different ergonomic desk designs and pencil grip patterns on handwriting performance in children with hemiplegic cerebral palsy and healthy children. METHODS:Twenty-six children with left hemiplegic cerebral palsy and 32 typically developing children wer...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.2223/JPED.1914
更新日期:2009-07-01 00:00:00
abstract:OBJECTIVE:To characterize the deaths of 193 children with sickle cell disease screened by a neonatal program from 1998 to 2012 and contrast the initial years with the final years. METHODS:Deaths were identified by active surveillance of children absent to scheduled appointments in Blood Bank Clinical Centers (Hemomina...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.1016/j.jped.2014.08.006
更新日期:2015-05-01 00:00:00
abstract::OBJECTIVE: Neonatal tetanus is an infection with high mortality, constituting a problem in underdeveloped countries, where there is faulty prenatal attendance. In spite of this and of the decreasing incidence of the disease in the state of Rio Grande do Sul, we report a case of neonatal tetanus identified in 1997. MET...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.2223/jped.80
更新日期:2000-09-01 00:00:00
abstract:OBJECTIVE:To investigate how well the parents of children on cow's milk free diets perform at recognizing whether or not expressions describe and foods contain cow's milk proteins. METHODS:Interviews were conducted with 24 parents of children on cow's milk and by-products exclusion diets and 23 parents of children wit...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.2223/JPED.1697
更新日期:2007-09-01 00:00:00
abstract:OBJECTIVE:To analyze acute splenic sequestration (ASS) in children with sickle cell anemia diagnosed through a newborn screening program in the state of Minas Gerais, Brazil, and followed up at the hematology center in the city of Belo Horizonte, Minas Gerais, Brazil. METHODS:Retrospective cohort of 255 children with ...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.2223/JPED.1885
更新日期:2009-03-01 00:00:00
abstract:OBJECTIVE:To analyze the evolution of pediatric patients chosen for hepatic transplantation. METHODS:A review was made of the clinical charts of the first 65 children and adolescents with chronic liver disease, aged 5 months to 19 years (X = 6.8%), chosen for liver transplantation during the period of August 1994 to M...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.2223/jped.511
更新日期:1997-03-01 00:00:00
abstract:OBJECTIVE:To assess the applicability of salivary C-reactive protein, mean platelet volume, neutrophil-lymphocyte ratio, and platelet lymphocyte ratio in the diagnosis of neonatal sepsis. METHODS:Prospective case-control study of 70 full-term neonates, 35 with sepsis (20 with proven sepsis and 15 with clinical sepsis)...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.1016/j.jped.2017.03.006
更新日期:2018-01-01 00:00:00
abstract:OBJECTIVES:To guide the diagnostic and therapeutic management of severe forms of food allergy. DATA SOURCES:Search in the Medline database using the terms "severe food allergy," "anaphylaxis and food allergy," "generalized urticaria and food allergy," and "food protein-induced enterocolitis syndrome" in the last ten y...
journal_title:Jornal de pediatria
pub_type: 杂志文章,评审
doi:10.1016/j.jped.2017.06.021
更新日期:2017-01-01 00:00:00
abstract:OBJECTIVE:To study the etiology of exanthema cases, with or without fever, in children seen in the emergency room of a hospital located in a region where dengue is endemic. METHODS:Enrollment took place between 21/09/2001 and 20/09/2002 and included 95.9% (71/74) of children presenting with exanthema at the emergency ...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.2223/JPED.1522
更新日期:2006-09-01 00:00:00
abstract:OBJECTIVE:To assess the occurrence of an aggregate risk to cardiometabolic and musculoskeletal health of Brazilian adolescents in the period 2008/09 and 2013/14 and to identify whether there are differences in risk between the genders and in these periods. METHODS:This was a trend epidemiological study with a quantita...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.1016/j.jped.2017.04.006
更新日期:2018-01-01 00:00:00
abstract:OBJECTIVE:To verify the concurrent validity and interobserver reliability of the Alberta Infant Motor Scale (AIMS) in premature infants followed-up at the outpatient clinic of Instituto Fernandes Figueira, Fundação Oswaldo Cruz (IFF/Fiocruz), in Rio de Janeiro, Brazil. METHODS:A total of 88 premature infants were enro...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.2223/JPED.1836
更新日期:2008-09-01 00:00:00
abstract:OBJECTIVE:To review the new options in insulin therapy for controlling diabetes mellitus in children and adolescents. SOURCES:Articles indexed in PubMed were located using the search terms insulin analogs in children and adolescents and reviewed. Information was also obtained from American Diabetes Association and Soc...
journal_title:Jornal de pediatria
pub_type: 杂志文章,评审
doi:10.2223/JPED.1712
更新日期:2007-11-01 00:00:00
abstract:OBJECTIVE:To develop a predictive model capable of identifying which premature infants have the greatest probability of presenting bronchopulmonary dysplasia (BPD), based on assessment at the end of their first week of life. METHODS:Data were collected retrospectively from January 1998 to July 2001, and prospectively ...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.2223/JPED.1599
更新日期:2007-03-01 00:00:00