Abstract:
OBJECTIVE:To compare the use of intravenous vs. oral antibiotic therapy. METHODS:All febrile neutropenic patients younger than 18 years old with low risk of complications and receiving chemotherapy were selected. The study was conducted from 2002 to 2005 at the Pediatric Oncology Unit of Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil. Patients were divided into group A and group B and were randomly assigned to receive oral or intravenous therapy. The empirical antimicrobial treatment used for group A consisted in oral ciprofloxacin plus amoxicillin-clavulanate and intravenous placebo, and group B received cefepime and oral placebo. RESULTS:A total of 91 consecutive episodes of febrile neutropenia in 58 children were included in the study. For patients of group A, treatment failure rate was 51.2%; the mean length of hospital stay was 8 days (range 2-10 days). For patients treated with intravenous antibiotic therapy, treatment failure rate was 45.8%; the mean length of hospital stay was 7 days (range 3-10 days). CONCLUSION:There was no difference in the outcome in oral vs. intravenous therapy. There is need of larger randomized trials before oral empirical therapy administered to this population should be considered the new standard of treatment.
journal_name
J Pediatr (Rio J)journal_title
Jornal de pediatriaauthors
Cagol AR,Castro Junior CG,Martins MC,Machado AL,Ribeiro RC,Gregianin LJ,Brunetto ALdoi
10.2223/JPED.1956subject
Has Abstractpub_date
2009-11-01 00:00:00pages
531-5issue
6eissn
0021-7557issn
1678-4782journal_volume
85pub_type
杂志文章,随机对照试验abstract:OBJECTIVE:To assess the incidence of brain death (BD) and its medical management and adopted protocols after its diagnosis in seven pediatric intensive care units (PICUs) located in three Brazilian regions. METHODS:A cross-sectional and multicenter study was conducted, based on the retrospective review of medical reco...
journal_title:Jornal de pediatria
pub_type: 杂志文章,多中心研究
doi:10.2223/JPED.1594
更新日期:2007-03-01 00:00:00
abstract:OBJECTIVE:To analyze acute splenic sequestration (ASS) in children with sickle cell anemia diagnosed through a newborn screening program in the state of Minas Gerais, Brazil, and followed up at the hematology center in the city of Belo Horizonte, Minas Gerais, Brazil. METHODS:Retrospective cohort of 255 children with ...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.2223/JPED.1885
更新日期:2009-03-01 00:00:00
abstract:OBJECTIVE:to assess the epidemiological and genetic factors associated with severity of acute viral bronchiolitis (AVB) by respiratory syncytial virus (RSV). DATA SOURCE:the key words "bronchiolitis", "risk factor", "genetics" and "respiratory syncytial virus", and all combinations among them were used to perform a se...
journal_title:Jornal de pediatria
pub_type: 杂志文章,评审
doi:10.1016/j.jped.2013.02.022
更新日期:2013-11-01 00:00:00
abstract:OBJECTIVE:To compare the effectiveness of salbutamol administration by metered-dose inhaler with a home-made spacer versus jet nebulizer in children with moderate wheezing attacks. MATERIAL AND METHODS:A randomized, single-blinded trial was performed with a convenience sample of children presenting wheezing. The child...
journal_title:Jornal de pediatria
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:2003-09-01 00:00:00
abstract:OBJECTIVE:To warn pediatricians about the high prevalence of bullying among students, to raise their awareness about the importance of their action in the prevention, diagnosis, and treatment of possible damage to children s health and development, and about the necessity to instruct families and society on how to face...
journal_title:Jornal de pediatria
pub_type: 杂志文章,评审
doi:10.2223/JPED.1403
更新日期:2005-11-01 00:00:00
abstract:OBJECTIVE:this study aimed to investigate the incidence of premature rupture of fetal membranes in preterm singleton pregnancies and its association with sociodemographic factors and maternal self-reported genitourinary infections. METHODS:this was a population-based cross-sectional study, which included all mothers o...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.1016/j.jped.2013.08.003
更新日期:2014-03-01 00:00:00
abstract::Having the purpose of identifying those newborn who have suffered from abnormal intrauterine growth, a standard of intrauterine growth has been drawn at the maternity ward of Hospital Regional da Asa Sul (HRAS-FHDF-Brasília), by studying the variables of weight, length, cephalic perimeter, weight of the placenta (with...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.2223/jped.696
更新日期:1995-01-01 00:00:00
abstract::The author describes television as a factor of influence in the sexual (mis)education in adolescence. He considers the role of eroticism in television as a dysfunctional factor in the sexual education of youth. In accordance with its pervasion, accessibility and attractive and seductive contents TV may be considered a...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.2223/jped.786
更新日期:1995-09-01 00:00:00
abstract:OBJECTIVE:To identify the relationship between admission hyperglycemia and outcome in children with severe brain injury at hospital discharge and 6 months later. METHOD:A retrospective analysis of blood glucose levels was conducted in 61 children with severe brain injury admitted to the Pediatric Intensive Care Unit b...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.2223/JPED.2097
更新日期:2011-07-01 00:00:00
abstract:OBJECTIVE:Plastic bronchitis is an unusual condition in children, associated with formation of mucofibrinous casts and mucous plugging of the tracheobronchial tree. Given that this illness is part of the differential diagnosis of acute respiratory failure, early treatment is important for improved prognosis. The aim of...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.2223/JPED.1425
更新日期:2005-11-01 00:00:00
abstract::OBJECTIVE: To verify the effects of malnutrition and nutritional rehabilitation regarding seizure threshold, body weight and brain weight in rats. METHODS: Pregnant Wistar rats and their pups were used. Part of the rat pups were submitted to a malnutrition protocol and the rest served as nourished controls. At P15, ma...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:
更新日期:2002-01-01 00:00:00
abstract:OBJECTIVE:To meta-analyze health-related quality of life in pediatric patients with chronic kidney disease in comparison to healthy patients according to the dimensions of the PedsQL instrument. SOURCES OF DATA:A systematic review was performed with meta-analysis for the mean difference in each of the health-related q...
journal_title:Jornal de pediatria
pub_type: 杂志文章,评审
doi:10.1016/j.jped.2020.10.013
更新日期:2020-12-17 00:00:00
abstract:OBJECTIVE:To evaluate retinol concentration in colostrum samples collected with a 24 hour interval. METHOD:Colostrum was collected from 24 recently-delivered mothers at two points in time, 0 hours (T0) and 24 hours later (T24), and a pooled sample of colostrum from T0 and T24 was also analyzed. Fat content was determi...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.2223/JPED.1646
更新日期:2007-07-01 00:00:00
abstract:OBJECTIVE:to determine the frequency, complications and seasonality at which respiratory syncytial virus (RSV) infection of the lower respiratory tract causes hospitalization in infants of age 1 year or less in 6 cities of Colombia. METHODS:one-year prospective multicentric observational study that included 717 patien...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.1016/j.jped.2013.04.002
更新日期:2013-11-01 00:00:00
abstract:OBJECTIVES:To assess the prevalence of congenital hypothyroidism and the ability of various neonatal thyroid-stimulating hormone (TSHneo) cutoff values to detect this disease. METHODS:This cohort study was based on the retrospective collection of information available from the Reference Service for Newborn Screening d...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.1016/j.jped.2016.07.006
更新日期:2017-01-01 00:00:00
abstract:OBJECTIVE:To evaluate the incidence of diarrheal disease (DD) and acute respiratory infection (ARI) in children undergoing supplementation of zinc and other micronutrients through the use of sprinkles, as well as their acceptance by these patients. METHOD:This was a randomized double-blinded clinical trial of 143 heal...
journal_title:Jornal de pediatria
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jped.2012.11.004
更新日期:2013-05-01 00:00:00
abstract:OBJECTIVES:To evaluate the possible effects of the introduction of the pneumococcal conjugate 10-valent vaccine schedule in the state of Parana on pneumococcal meningitis cases and to assess the distribution of serotypes among cases. METHOD:Cross-sectional study with retrospective data collection of cases of pneumococ...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.1016/j.jped.2014.07.002
更新日期:2015-03-01 00:00:00
abstract:OBJECTIVES:To describe the prevalence of and factors associated with overweight in children under 4 years of age in Feira de Santana, state of Bahia, Brazil. METHODS:Cross-sectional study nested within a birth cohort of 793 children born in Feira de Santana, Brazil. Independent variables were related to infant charact...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.2223/JPED.2009
更新日期:2010-07-01 00:00:00
abstract::OBJECTIVE: Describe the morbidity associated with a rare disease due to an embryological defect. METHODS: Retrospective revision of medical and necropsy reports. Bibliographic research using MEDLINE, LILACS and Index Medicus databases. RESULTS: 1 year-old male patient, admitted with generalized tonic-clonic seizures, ...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.2223/jped.320
更新日期:1999-07-01 00:00:00
abstract:OBJECTIVE:The main concepts involved in the therapeutic management of intracranial hypertension are revisited, including pathophysiology, monitoring, the traditional approach, and also the presentation of recently proposed therapies. SOURCE OF DATA:The main medical literature data bases (especially Medline and Lilacs)...
journal_title:Jornal de pediatria
pub_type: 杂志文章,评审
doi:10.2223/jped.1090
更新日期:2003-11-01 00:00:00
abstract:OBJECTIVES:To evaluate sleep architecture in children and adolescents with both cystic fibrosis (CF) and a clinical suspicion of sleep-disordered breathing (SDB), and to identify the respiratory polysomnographic profile of these patients. METHODS:Parents or guardians of children with CF filled out a questionnaire desi...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.2223/JPED.2055
更新日期:2011-01-01 00:00:00
abstract:OBJECTIVE:To evaluate the peak inspiratory pressure, tidal volume and respiratory rate achieved during manual ventilation of premature lambs, using a self-inflating bag. METHODS:In this descriptive, experimental study, five pairs of physicians, selected at random among 35 neonatologists working at a neonatal intensive...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.2223/JPED.1517
更新日期:2006-07-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to investigate the effect of different ergonomic desk designs and pencil grip patterns on handwriting performance in children with hemiplegic cerebral palsy and healthy children. METHODS:Twenty-six children with left hemiplegic cerebral palsy and 32 typically developing children wer...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.2223/JPED.1914
更新日期:2009-07-01 00:00:00
abstract:OBJECTIVE:to evaluate changes in the biochemical profile of children treated or being treated for moderate or severe stunting in a nutrition recovery and education center. METHODS:this was a retrospective longitudinal study of 263 children treated at this center between August of 2008 to August of 2011, aged 1 to 6 ye...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.1016/j.jped.2013.12.007
更新日期:2014-07-01 00:00:00
abstract:OBJECTIVE:To describe the characteristics of macrophage activation syndrome associated with juvenile idiopathic arthritis. DESCRIPTION:This is a retrospective study involving 462 patients with juvenile idiopathic arthritis. Seven (1.5%) of those patients suffered from systemic onset juvenile idiopathic arthritis and d...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:
更新日期:2004-11-01 00:00:00
abstract::The purpose of the authors in this article was to evaluate the effects of supplementing maternal milk with two different caloric formulas on the growth of premature newborns until they reached 40 weeks of post-conceptional age. Seventy premature infants weighing < 1750g at birth were randomized: 35 adequate for gestat...
journal_title:Jornal de pediatria
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.2223/jped.607
更新日期:1996-05-01 00:00:00
abstract:OBJECTIVE:To analyze some factors related to injuries and children and adolescents' hospitalization. METHODS:This is a prospective, descriptive and observational research that took place at Marcio Cunha Hospital, Ipatinga, Minas Gerais, in the period of December 1st, 1999 to November 30th, 2000. The sample included 69...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:
更新日期:2004-11-01 00:00:00
abstract:OBJECTIVES:To evaluate the association between the genetic polymorphism of the tumor necrosis factor-alpha (TNF-α) gene and the development of sepsis and septic shock in Thai pediatric patients and to investigate the clinical impacts of TNF-α polymorphisms in this population. METHODS:To perform this genetic associatio...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.2223/JPED.2216
更新日期:2012-09-01 00:00:00
abstract::OBJECTIVE: To present, in practical form and updated terms, the clinical aspects of the varicella and its prevention using either vaccination or isolation precautions. METHOD: Review of the literature using MEDLINE and LILACS referring to the last 10 years; presentation of the most recent aspects in the literature as ...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.2223/jped.379
更新日期:1999-07-01 00:00:00
abstract:OBJECTIVE:To describe the main predictors for excess birth weight in Brazilian children. DATA SOURCES:Systematic review carried out in the bibliographic databases: PubMed/MEDLINE, Cochrane, Scopus, Web of Science, and LILACS. The research in the gray literature was performed using the Google Scholar database. The bias...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.1016/j.jped.2018.04.006
更新日期:2019-01-01 00:00:00