Abstract：
OBJECTIVE:To compare the effectiveness of salbutamol administration by metered-dose inhaler with a home-made spacer versus jet nebulizer in children with moderate wheezing attacks. MATERIAL AND METHODS:A randomized, single-blinded trial was performed with a convenience sample of children presenting wheezing. The children were enrolled in an emergency room and randomly assigned to one of two treatment groups: home-made spacer group or nebulizer group. Clinical scores and oxygen saturation were recorded at baseline and 15 minutes after salbutamol administration. Treatment with salbutamol (100 microg/3 kg in the spacer group, and 250 microg/3 kg in the nebulizer group) was repeated at 20-minute intervals, until the child was considered to have improved significantly, with no need of any further dose, or until three doses were delivered. Treatment cost, time spent to prepare and deliver the drug, and level of parental satisfaction with the treatment were recorded. RESULTS:Fifty-four children with age between 22 days and 11.7 years were enrolled--27 in each group. Baseline and demographic characteristics were similar for both groups. The spacer was as effective as the nebulizer in terms of clinical score and oxygen saturation. The different doses (100 microg/3 kg with the spacer, and 250 microg/3 kg with the nebulizer) were shown to be clinically equivalent. Treatment cost was significantly lower in the spacer group, as was the time to prepare and deliver the drug. Parental satisfaction was similar for both inhaler devices. CONCLUSION:The home-made spacer with a metered-dose inhaler is a cost-effective alternative to a jet nebulizer in the delivery of salbutamol to children with moderate wheezing attacks.
journal_name
J Pediatr (Rio J)journal_title
Jornal de pediatriaauthors
Vilarinho LC,Cardeal Mendes CM,de Freitas Souza LSkeywords:
subject
Has Abstractpub_date
2003-09-01 00:00:00pages
403-12issue
5eissn
0021-7557issn
1678-4782journal_volume
79pub_type
临床试验,杂志文章,随机对照试验abstract：OBJECTIVE:To review the literature on the effects of parental divorce over the psychological maladjustment and physical health problems in children of divorced parents, thus contributing to the integration of existing scientific knowledge based on the biopsychosocial model of the impact of divorce on children's physica...
journal_title：Jornal de pediatria
pub_type： 杂志文章,评审
doi：10.2223/JPED.1925
更新日期：2009-09-01 00:00:00
abstract：OBJECTIVE:The modified shuttle test is a field test that avoids the ceiling effect, and there are no reports of a multidimensional assessment concerning physical activity in asthmatic patients. Thus, the aim was to evaluate functional capacity by MST, additionally to perform a multidimensional assessment as physical ac...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.1016/j.jped.2018.07.011
更新日期：2020-01-01 00:00:00
abstract：OBJECTIVE:A review article was carried out, addressing the clinical and epidemiological characteristics of immune system deficiencies, which are associated with or predispose to recurrent infectious processes, autoimmune diseases, auto inflammatory diseases, or neoplasms, and which are classified as inborn errors of im...
journal_title：Jornal de pediatria
pub_type： 杂志文章,评审
doi：10.1016/j.jped.2020.10.009
更新日期：2020-11-22 00:00:00
abstract：:OBJECTIVE: Neonatal tetanus is an infection with high mortality, constituting a problem in underdeveloped countries, where there is faulty prenatal attendance. In spite of this and of the decreasing incidence of the disease in the state of Rio Grande do Sul, we report a case of neonatal tetanus identified in 1997. MET...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.2223/jped.80
更新日期：2000-09-01 00:00:00
abstract：OBJECTIVE:To evaluate the presence of insulin resistance and its association with other metabolic abnormalities in obese children and adolescents. METHODS:Retrospective study of 220 children and adolescents aged 5-14 years. Anthropometric measurements were performed (weight, height, and waist circumference) and clinic...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.1016/j.jped.2014.03.005
更新日期：2014-11-01 00:00:00
abstract：OBJECTIVE:To analyze the influence of obesity status on immune cell count and concentration of the hormones cortisol and leptin, in order to establish a relationship among the variables analyzed. METHODS:We recruited 27 obese [body mass index (BMI) > or = 95th percentile] and 21 non-obese (BMI < or = 75th percentile) ...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.2223/JPED.1845
更新日期：2008-11-01 00:00:00
abstract：OBJECTIVE:To evaluate the incidence of diarrheal disease (DD) and acute respiratory infection (ARI) in children undergoing supplementation of zinc and other micronutrients through the use of sprinkles, as well as their acceptance by these patients. METHOD:This was a randomized double-blinded clinical trial of 143 heal...
journal_title：Jornal de pediatria
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.jped.2012.11.004
更新日期：2013-05-01 00:00:00
abstract：OBJECTIVE:To evaluate the association of intimate partner violence during the gestational period and the development of externalizing and internalizing behavioral problems in children and adolescents. SOURCE OF DATA:A meta-analysis of cohort and case-control studies was performed, using studies selected from electroni...
journal_title：Jornal de pediatria
pub_type： 杂志文章,评审
doi：10.1016/j.jped.2018.01.007
更新日期：2018-01-01 00:00:00
abstract：OBJECTIVE:To present, in an essay form, two distinct views on well-child care. METHODS:Using several different methods of historical analysis, the two most common views on well-child care are presented: the positivist one, whose foundation is essentially based upon historical facts, and that of social criticism, conce...
journal_title：Jornal de pediatria
pub_type： 历史文章,杂志文章
doi：
更新日期：2005-01-01 00:00:00
abstract：OBJECTIVE:To characterize varicella zoster virus-related deaths and hospitalizations in Brazil before universal vaccination with the tetravalent (measles, mumps, rubella, and varicella) vaccine, attempting to collect baseline data on varicella morbidity and mortality in order to evaluate the impact of the varicella vac...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.1016/j.jped.2015.10.003
更新日期：2016-07-01 00:00:00
abstract：OBJECTIVE:To assess the carotid intima-media thickness and factors associated with cardiovascular disease in children and adolescents with chronic kidney disease. MATERIAL AND METHODS:Observational, cross-sectional study carried out at the Universidade Federal de São Paulo (chronic kidney disease outpatient clinics) w...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.1016/j.jped.2018.06.010
更新日期：2019-01-01 00:00:00
abstract：OBJECTIVES:To perform a bibliometric analysis of theses and dissertations on prematurity in the Capes database from 1987 to 2009. METHODS:This is a descriptive study that used the bibliometric approach for the production of indicators of scientific production. Operationally, the methodology was developed in four steps...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.2223/JPED.2232
更新日期：2012-11-01 00:00:00
abstract：:OBJECTIVES: To identify rubella prevalence in different ages and population groups and rubella susceptibility of pregnant and postpartum women according to age, number of children and spontaneous abortion. METHODS: Cross-sectional study of sero-survey type. Children and students were selected in day-care centers and s...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.2223/jped.470
更新日期：1998-11-01 00:00:00
abstract：:OBJECTIVE: To make a brief review about mechanical ventilation in Pediatrics.METHODS: Review of the classification of types of mechanical ventilation, characteristics of pression and flow waves and indications for its installation. In a sequential way we discuss the various modes of ventilation (control ventilation, a...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.2223/jped.476
更新日期：1998-07-01 00:00:00
abstract：OBJECTIVE:to investigate the pulmonary response to exercise of non-morbidly obese adolescents, considering the gender. METHODS:a prospective cross-sectional study was conducted with 92 adolescents (47 obese and 45 eutrophic), divided in four groups according to obesity and gender. Anthropometric parameters, pulmonary ...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.1016/j.jped.2013.08.005
更新日期：2014-05-01 00:00:00
abstract：OBJECTIVE:To measure the main risk factors associated with the occurrence of accidental injuries in children aged 4-5 years. METHODS:The study included a prospective cohort of children whose parents filled in a diary recording accidents and injuries during a period of one-month. The children represented a systematic s...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：
更新日期：2002-03-01 00:00:00
abstract：OBJECTIVE:Report the incidence, epidemiology, clinical features, death, and vaccination status of patients with whooping cough and perform genotypic characterization of isolates of B. pertussis identified in the state of Paraná, during January 2007 to December 2013. METHODS:Cross-sectional study including 1,209 patien...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.1016/j.jped.2014.09.004
更新日期：2015-07-01 00:00:00
abstract：:OBJECTIVE: To determine ASO titer profile by establishing ARF differential diagnoses of other diseases with high levels of ASO antibodies. METHODS: We investigated 78 patients with ARF at onset and follow-up, 22 with isolated chorea at onset, 45 with recurrent oropharyngeal tonsillitis, and 23 with recent flare of juv...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.2223/jped.185
更新日期：2001-03-01 00:00:00
abstract：OBJECTIVE:To estimate the frequency and describe the clinical characteristics and respective treatments of previous history of wheezing. METHODS:Infants aged 6-23 months with upper respiratory tract complaints and reporting previous wheezing were followed-up retrospectively. Data were registered on a validated standar...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.2223/JPED.2187
更新日期：2012-07-01 00:00:00
abstract：OBJECTIVE:To evaluate the peak inspiratory pressure, tidal volume and respiratory rate achieved during manual ventilation of premature lambs, using a self-inflating bag. METHODS:In this descriptive, experimental study, five pairs of physicians, selected at random among 35 neonatologists working at a neonatal intensive...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.2223/JPED.1517
更新日期：2006-07-01 00:00:00
abstract：:OBJECTIVE: Morbidity and mortality of premature infants have decreased considerably over the last decades, therefore, adequate nutrition of the premature is a major concern. Enteral feeding is the route of choice, but when it is not possible the parenteral route, which contains glucose as one of its main components, i...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.2223/jped.463
更新日期：1998-09-01 00:00:00
abstract：OBJECTIVE:Assess the maternal socio-demographic factors associated with the frequency of use of child care services by low income families. METHODS:Cross-sectional analysis of 393 children between 12 and 16 months old who participated in a randomized field trial during their first year of life in a program of nutritio...
journal_title：Jornal de pediatria
pub_type： 杂志文章,随机对照试验
doi：10.2223/JPED.1966
更新日期：2010-01-01 00:00:00
abstract：OBJECTIVE:To study epidemiological and clinical aspects of American visceral leishmaniasis in hospitalized children in Ceará, Brazil. METHODS:A retrospective and observational study was carried out with children suffering from American visceral leishmaniasis admitted to Hospital Infantil Albert Sabin in Fortaleza. Med...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：
更新日期：2005-01-01 00:00:00
abstract：OBJECTIVE:The aim of this study was to determine the prevalence of infection versus the prevalence of contamination in infants less than 60 days old who had blood cultures positive for CoNS. MATERIAL AND METHODS:Between February and June - 1993, a number of 45 blood cultures positive for CoNS from 41 patients were stu...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.2223/jped.524
更新日期：1997-05-01 00:00:00
abstract：OBJECTIVE:The aim of this study was to perform a review to investigate the influence of breastfeeding as a protective agent against the onset of diabetes in children. SOURCES:non-systematic review of SciELO, LILACS, MEDLINE, Scopus, and VHL databases, and selection of the 52 most relevant studies. A total of 21 articl...
journal_title：Jornal de pediatria
pub_type： 杂志文章,评审
doi：10.1016/j.jped.2013.02.024
更新日期：2014-01-01 00:00:00
abstract：OBJECTIVE:To study bone density as a concomitant factor for obesity in post-pubertal adolescents, controlling for other variables that may interfere in such a relation. METHODS:Study comprising 83 overweight and obese adolescents (BMI > or = P85) and 89 non obese ones (P5 < or = BMI < or = P85). Cases and controls wer...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：
更新日期：2005-07-01 00:00:00
abstract：OBJECTIVE:To review the most important aspects of the clinical presentation and treatment of children with cancer in intensive care units. SOURCE OF DATA:Medline (1970 to 2003); search terms: children, cancer, oncology, intensive care, complications. General and pediatric oncology textbooks. SUMMARY OF THE FINDINGS:P...
journal_title：Jornal de pediatria
pub_type： 杂志文章,评审
doi：10.2223/jped.1100
更新日期：2003-11-01 00:00:00
abstract：OBJECTIVE:Several reports claim that blood pressure (BP) in the radial artery may underestimate the accurate BP in critically ill patients. Here, the authors evaluated differences in mean blood pressure (MBP) between the radial and femoral artery during pediatric cardiac surgery to determine the effectiveness of femora...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.1016/j.jped.2017.03.011
更新日期：2018-01-01 00:00:00
abstract：OBJECTIVE:The aim of this study was to identify the causes of congenital microcephaly in Rio Grande do Sul, a state in southern Brazil, where no ZIKV outbreak was detected, from December 2015 to December 2016, which was the period when ZIKV infection was at its peak in northeast Brazil. METHODS:This was a cross-sectio...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.1016/j.jped.2018.05.013
更新日期：2019-01-01 00:00:00
abstract：OBJECTIVE:To identify risk factors for neonatal mortality, focusing on factors related to assistance care during the prenatal period, childbirth, and maternal reproductive history. METHODS:This was a case-control study conducted in Maceió, Northeastern Brazil. The sample consisted of 136 cases and 272 controls selecte...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.1016/j.jped.2012.11.005
更新日期：2013-05-01 00:00:00
