Abstract：
OBJECTIVE:To assess the applicability of salivary C-reactive protein, mean platelet volume, neutrophil-lymphocyte ratio, and platelet lymphocyte ratio in the diagnosis of neonatal sepsis. METHODS:Prospective case-control study of 70 full-term neonates, 35 with sepsis (20 with proven sepsis and 15 with clinical sepsis) and 35 healthy controls. Serum and salivary C-reactive protein concentrations were measured by enzyme-linked immunosorbent assay while mean platelet volume, neutrophil-lymphocyte ratio, and platelet lymphocyte ratio were measured by automated blood cell counter. RESULTS:This study showed statistically significant difference of mean salivary C-reactive protein between septic neonates and controls (12.0±4.6ng/L vs. 2.8±1.2ng/L) respectively. At a cut-off point of 3.48ng/L, salivary C-reactive protein showed 94.3% sensitivity and 80% specificity. Salivary C-reactive protein also showed good predictive accuracy for predicting elevated serum C-reactive protein values in septic neonates. Mean platelet volume and neutrophil-lymphocyte ratio showed significant difference between septic neonates and controls (10.2±1.2fL vs.8.0±0.5fL; 2.9±1.7 vs. 1.6±0.4, respectively). At a cut-off point of 10.2fL, mean platelet volume presented 80% sensitivity and specificity. At a cut-off point of 2.7, neutrophil-lymphocyte ratio presented 80% sensitivity and 57.1% specificity. CONCLUSION:This study provides support for further studies on the usefulness of salivary C-reactive protein, mean platelet volume, and neutrophil-lymphocyte ratio as diagnostic markers for neonatal sepsis.
journal_name
J Pediatr (Rio J)journal_title
Jornal de pediatriaauthors
Omran A,Maaroof A,Saleh MH,Abdelwahab Adoi
10.1016/j.jped.2017.03.006subject
Has Abstractpub_date
2018-01-01 00:00:00pages
82-87issue
1eissn
0021-7557issn
1678-4782pii
S0021-7557(16)30403-Xjournal_volume
94pub_type
杂志文章abstract：OBJECTIVE:To investigate the extent to which sexual orientation-based bullying relates to self-reported feelings of loneliness and sleeping difficulty among Brazilian middle school students. METHOD:This is a cross-sectional study using data from the 2015 PeNSE (Pesquisa Nacional de Saúde do Escolar), a survey designed...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.1016/j.jped.2020.03.005
更新日期：2020-04-15 00:00:00
abstract：OBJECTIVE:to evaluate neonatal sepsis as a risk factor for abnormal neuromotor and cognitive development in very low birth weight preterm infants at 12 months of corrected age. METHODS:this was a prospective cohort study that followed the neuromotor and cognitive development of 194 very low birth weight preterm infant...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.1016/j.jped.2013.09.006
更新日期：2014-05-01 00:00:00
abstract：OBJECTIVE:The modified shuttle test is a field test that avoids the ceiling effect, and there are no reports of a multidimensional assessment concerning physical activity in asthmatic patients. Thus, the aim was to evaluate functional capacity by MST, additionally to perform a multidimensional assessment as physical ac...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.1016/j.jped.2018.07.011
更新日期：2020-01-01 00:00:00
abstract：:OBJECTIVES: The aims of this review are to present research data about aerosoltherapy and to discuss the optimization of this form of drug administration.METHOD: Review of the literature, covering some of the most important studies about aerosoltherapy, inhaler devices, pharmacokinetics and pharmacodynamics of inhaled...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.2223/jped.428
更新日期：1998-05-01 00:00:00
abstract：OBJECTIVE:The aim of this study was to investigate the effect of different ergonomic desk designs and pencil grip patterns on handwriting performance in children with hemiplegic cerebral palsy and healthy children. METHODS:Twenty-six children with left hemiplegic cerebral palsy and 32 typically developing children wer...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.2223/JPED.1914
更新日期：2009-07-01 00:00:00
abstract：OBJECTIVE:To report the case of two siblings with chronic granulomatous disease. Chronic granulomatous disease is a primary immunodeficiency disorder characterized by abnormal microbicidal activity. Mutations in the p47-phox gene (NCF-1) are present in about 30% of the patients with chronic granulomatous disease; this ...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：
更新日期：2004-09-01 00:00:00
abstract：:OBJECTIVE: To review the use of corticosteroids in the treatment of newborns with chronic lung disease, adrenal insufficiency and upper airway edema. SOURCES: Review of the available medical literature on the use of corticosteroids in newborns. SUMMARY OF THE FINDINGS: Although there is evidence of short-term clinical...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.2223/jped.216
更新日期：2001-07-01 00:00:00
abstract：OBJECTIVE:To determine the prevalence of celiac disease and to describe the histological alterations, clinical manifestations, and conditions associated with a group of first-degree relatives of celiac disease patients in the municipality of Recife, Northeast Brazil. METHOD:The study was conducted in outpatient clinic...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.2223/JPED.2013
更新日期：2010-07-01 00:00:00
abstract：OBJECTIVE:To investigate the immune response of preterm infants to hepatitis B vaccination. METHODS:Three doses of recombinant hepatitis B vaccine (5 micro g dose) were administered to 35 preterm and 21 full-term infants within 24 hours after birth and at one and six months of postnatal age. RESULTS:A protective anti...
journal_title：Jornal de pediatria
pub_type： 临床试验,杂志文章
doi：
更新日期：2004-03-01 00:00:00
abstract：OBJECTIVE:Evaluate the prevalence of retinopathy of prematurity (ROP) in very low birthweight infants (birthweight<1500 g). METHOD:A prospective examination was conducted on 102 neonates with very low birthweight admitted to the BAM-HC (FMUSP) between 01/01/92 and 12/31/93. The mapping of the retina with scleral depre...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.2223/jped.564
更新日期：1997-11-01 00:00:00
abstract：OBJECTIVE:To observe the intensity of the inflammatory reaction caused by urine on the intestinal wall of rats. METHODS:Experimental model, using 20 Wistar rats divided into two groups. All the animals were submitted to abdominal puncture at the right inferior quadrant, twice daily for five days. In Group I (control g...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.2223/jped.1113
更新日期：2003-11-01 00:00:00
abstract：OBJECTIVE:To emphasize the importance of precocious diagnosis of extrahepatic biliary atresia and its direct relationship with the surgical re-establishment of the biliary flow before the second month of life. To discuss several complementary methods with the aim of selecting the ones that present better evidence, and ...
journal_title：Jornal de pediatria
pub_type： 杂志文章,评审
doi：
更新日期：2003-03-01 00:00:00
abstract：OBJECTIVE:To measure the prevalence of children with adequate weight who feel fat and to examine the factors associated with this perception. METHODS:Cross-sectional study with 901 schoolchildren aged 8-11 years selected by cluster sampling. The children had their weight and height measured, and answered a questionnai...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.2223/JPED.1477
更新日期：2006-05-01 00:00:00
abstract：OBJECTIVE:To review the new options in insulin therapy for controlling diabetes mellitus in children and adolescents. SOURCES:Articles indexed in PubMed were located using the search terms insulin analogs in children and adolescents and reviewed. Information was also obtained from American Diabetes Association and Soc...
journal_title：Jornal de pediatria
pub_type： 杂志文章,评审
doi：10.2223/JPED.1712
更新日期：2007-11-01 00:00:00
abstract：:OBJECTIVES: To identify rubella prevalence in different ages and population groups and rubella susceptibility of pregnant and postpartum women according to age, number of children and spontaneous abortion. METHODS: Cross-sectional study of sero-survey type. Children and students were selected in day-care centers and s...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.2223/jped.470
更新日期：1998-11-01 00:00:00
abstract：OBJECTIVE:To evaluate the prevalence of intestinal parasitoses in Native Brazilian children from 2 to 9 years old. METHODS:A search for ova and parasites was conducted in the stools of children between 2 to 9 years old living in six indigenous villages located in the Middle and Lower Xingu River, to wit: Pavuru, Moygu...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.2223/JPED.2036
更新日期：2010-11-01 00:00:00
abstract：OBJECTIVE:To review the most important aspects of the clinical presentation and treatment of children with cancer in intensive care units. SOURCE OF DATA:Medline (1970 to 2003); search terms: children, cancer, oncology, intensive care, complications. General and pediatric oncology textbooks. SUMMARY OF THE FINDINGS:P...
journal_title：Jornal de pediatria
pub_type： 杂志文章,评审
doi：10.2223/jped.1100
更新日期：2003-11-01 00:00:00
abstract：OBJECTIVE:To evaluate the incidence of diarrheal disease (DD) and acute respiratory infection (ARI) in children undergoing supplementation of zinc and other micronutrients through the use of sprinkles, as well as their acceptance by these patients. METHOD:This was a randomized double-blinded clinical trial of 143 heal...
journal_title：Jornal de pediatria
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.jped.2012.11.004
更新日期：2013-05-01 00:00:00
abstract：:OBJECTIVE: To study plasma levels of IL-1beta and IL-6 in order to distinguish the presence of bacterial infection in newborn infants with fever. METHODS: A cohort of 117 newborn infants with postnatal age equal to or less than 5 days, with no previous use of antibiotic therapy, and with clinical suspicion of bacteria...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.2223/jped.253
更新日期：1999-01-01 00:00:00
abstract：OBJECTIVE:To carry out a systematic review on the relationship of bullying with type 1 diabetes in children and adolescents. METHODS:Systematic review, according to the PRISMA methodology, in which the databases PubMed, Web of Science, Scopus, Thomson Reuters, Eighteenth Century Collections Online, Begell House Digita...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.1016/j.jped.2018.10.003
更新日期：2019-01-01 00:00:00
abstract：OBJECTIVE:this study aimed to investigate the incidence of premature rupture of fetal membranes in preterm singleton pregnancies and its association with sociodemographic factors and maternal self-reported genitourinary infections. METHODS:this was a population-based cross-sectional study, which included all mothers o...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.1016/j.jped.2013.08.003
更新日期：2014-03-01 00:00:00
abstract：:OBJECTIVE: Describe the hemodynamic response with rebound of pulmonary hypertension after withdrawal of inhaled nitric oxide (NO) in a pediatric patient with acute respiratory distress syndrome (ARDS). METHODS: Case report of a child with ARDS and pulmonary hypertension evaluated through ecocardiografic with dopller, ...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.2223/jped.59
更新日期：2000-03-01 00:00:00
abstract：OBJECTIVE:To present a wide-ranging review of the literature on broncopulmonary dysplasia, covering new definitions, pathophysiology, prevention, treatment, prognosis and progression. SOURCES OF DATA:The most relevant articles published on the subject since it was first described in 1967 were selected from MEDLINE sea...
journal_title：Jornal de pediatria
pub_type： 杂志文章,评审
doi：
更新日期：2005-03-01 00:00:00
abstract：:OBJECTIVE: To establish the nutritional diagnosis of children living in a low-income community through anthropometric evaluation, detecting insufficient nutrition (low weight-for-age, wasting and stunting) and excessive nutrition (overweight and obesity). METHODS: A community-based survey identified children below 11 ...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.2223/jped.236
更新日期：2001-07-01 00:00:00
abstract：:OBJECTIVE: To assess the prevalence of prenatal exposure to cocaine in a sample of newborns using two methods: fluorescence polarization immunoassay and interview with the mother. METHODS: This cross-sectional study was carried out in a university teaching hospital. The population included all live births between Marc...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.2223/jped.277
更新日期：2001-09-01 00:00:00
abstract：OBJECTIVES:To assess the prevalence of congenital hypothyroidism and the ability of various neonatal thyroid-stimulating hormone (TSHneo) cutoff values to detect this disease. METHODS:This cohort study was based on the retrospective collection of information available from the Reference Service for Newborn Screening d...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.1016/j.jped.2016.07.006
更新日期：2017-01-01 00:00:00
abstract：OBJECTIVE:To correlate different methods of body composition assessment in overweight or obese schoolchildren, using deuterium oxide (D2O) dilution as a reference. METHODS:Percentage of total body water (%TBW), fat free mass (%FFM), and body fat (%BF) were assessed by D2O and tetrapolar electrical bioimpedance analysi...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.1016/j.jped.2015.03.007
更新日期：2016-01-01 00:00:00
abstract：OBJECTIVE:To verify the concurrent validity and interobserver reliability of the Alberta Infant Motor Scale (AIMS) in premature infants followed-up at the outpatient clinic of Instituto Fernandes Figueira, Fundação Oswaldo Cruz (IFF/Fiocruz), in Rio de Janeiro, Brazil. METHODS:A total of 88 premature infants were enro...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.2223/JPED.1836
更新日期：2008-09-01 00:00:00
abstract：:The author describes television as a factor of influence in the sexual (mis)education in adolescence. He considers the role of eroticism in television as a dysfunctional factor in the sexual education of youth. In accordance with its pervasion, accessibility and attractive and seductive contents TV may be considered a...
journal_title：Jornal de pediatria
pub_type： 杂志文章
doi：10.2223/jped.786
更新日期：1995-09-01 00:00:00
abstract：OBJECTIVE:To evaluate the association of intimate partner violence during the gestational period and the development of externalizing and internalizing behavioral problems in children and adolescents. SOURCE OF DATA:A meta-analysis of cohort and case-control studies was performed, using studies selected from electroni...
journal_title：Jornal de pediatria
pub_type： 杂志文章,评审
doi：10.1016/j.jped.2018.01.007
更新日期：2018-01-01 00:00:00
