Abstract：
:It has been half a century since brain volume enlargement was first reported in animals reared in an enriched environment (EE). As EE animals show improved memory task performance, exposure to EE has been a useful model system for studying the effects of experience on brain plasticity. We review EE-induced neural changes in the cerebral cortex and hippocampus focusing mainly on works published in the recent decade. The review is organized in three large domains of changes: anatomical, electrophysiological, and molecular changes. Finally, we discuss open issues and future outlook toward better understanding of EE-induced neural changes.
journal_name
Neurosciencejournal_title
Neuroscienceauthors
Hirase H,Shinohara Ydoi
10.1016/j.neuroscience.2014.09.031subject
Has Abstractpub_date
2014-11-07 00:00:00pages
282-98eissn
0306-4522issn
1873-7544pii
S0306-4522(14)00780-5journal_volume
280pub_type
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