Agrin induced morphological and structural changes in growth cones of cultured hippocampal neurons.

abstract：:Experimental autoimmune dementia is a rat model designed to examine the potential role of anti-cholinergic neurons antibodies in neuronal degeneration in dementia and Alzheimer's disease. We have previously shown that sera of patients with Alzheimer's disease contain antibodies which bind specifically to the high mole...

journal_title：Neuroscience

authors： Eilam D,Szechtman H,Faigon M,Dubovik V,Feldon J,Michaelson DM

更新日期：1993-09-01 00:00:00

abstract：:Our human visual system exploits spatiotemporal regularity to interpret incoming visual signals. With a dynamic stimulus sequence of four collinear bars (predictors) appearing consecutively toward the fovea, followed by a target bar with varying contrasts, we have previously found that this predictable spatiotemporal ...

journal_title：Neuroscience

authors： Roebuck H,Bourke P,Guo K

更新日期：2014-03-28 00:00:00

abstract：:Opiate addiction is a chronic medical disorder characterized by drug tolerance and dependence, behavioral sensitization, vulnerability to compulsive relapse, and high mortality. In laboratory animals, the potential effect of opiate drugs to induce cell death by apoptosis is a controversial topic. This postmortem human...

journal_title：Neuroscience

authors： García-Fuster MJ,Ramos-Miguel A,Rivero G,La Harpe R,Meana JJ,García-Sevilla JA

更新日期：2008-11-11 00:00:00

abstract：:A satisfactory management to ensure a full restoration of peripheral nerve after trauma is not yet available. Using an experimental protocol, in which crush injury was applied 1 cm above the bifurcation of the rat sciatic nerve for 20 s, we here demonstrate that the levels of neuroactive steroids, such as pregnenolone...

journal_title：Neuroscience

authors： Roglio I,Bianchi R,Gotti S,Scurati S,Giatti S,Pesaresi M,Caruso D,Panzica GC,Melcangi RC

更新日期：2008-08-26 00:00:00

abstract：:The midbrain periaqueductal gray matter has been identified as a reflex centre located uppermost in the central organization of diverse defensive reactions. We recently found that when activated, the caudal third of the lateral periaqueductal gray was also capable of provoking a marked increase in cortical blood flow....

journal_title：Neuroscience

authors： Nakai M,Ogata J,Fukui K,Nakai Y,Maeda M

更新日期：1997-07-01 00:00:00

abstract：:Accumulated evidence suggests that the single transmembrane domain insulin-like growth factor-II/mannose 6-phosphate receptor (IGF-II/M6P or IGF-II receptor) plays an important role in the intracellular trafficking of lysosomal enzymes and endocytosis-mediated degradation of insulin like growth factor (IGF-II). Howeve...

journal_title：Neuroscience

authors： Amritraj A,Rauw G,Baker GB,Kar S

更新日期：2010-10-27 00:00:00

abstract：:Dementia, especially Alzheimer's disease, is a rapidly increasing medical condition that presents with enormous challenge for treatment. It is characterized by impairment in memory and cognitive function often accompanied by changes in synaptic transmission and plasticity in relevant brain regions such as the hippocam...

journal_title：Neuroscience

authors： Nashawi H,Bartl T,Bartl P,Novotny L,Oriowo MA,Kombian SB

更新日期：2012-09-18 00:00:00

abstract：:The p38 member of the mitogen-activated protein kinase superfamily is engaged by phosphorylation in response to environmental stress signals, and may have either permissive or inhibitor roles upon cell proliferation. The cell cycle in the proliferative zone of the retina is tightly controlled and proceeds in synchrony...

journal_title：Neuroscience

authors： Campos CB,Bédard PA,Linden R

更新日期：2002-01-01 00:00:00

abstract：:Golgi, Nissl, Bielschowsky and cholinesterase techniques have been used to analyze the optic tectum of the weakly electric teleost fish Eigenmannia virescens and Apteronotus leptorhynchus. Six layers are readily distinguished: a fairly thick stratum marginale, a narrow stratum opticum and stratum fibrosum et griseum s...

journal_title：Neuroscience

authors： Sas E,Maler L

更新日期：1986-05-01 00:00:00

abstract：:Arising from studies on the amnesia that follows site-specific physical or chemical lesions, the acquisition and consolidation of certain behavioral tasks has been demonstrated to be associated with different hippocampal subregions. Although not absolute, spatial learning is reliant on the dorsal region of the hippoca...

journal_title：Neuroscience

authors： Scully D,Fedriani R,Desouza IE,Murphy KJ,Regan CM

更新日期：2012-05-03 00:00:00

abstract：:The zebrafish olfactory system is a valuable model for examining neural regeneration after damage due to the remarkable plasticity of this sensory system and of fish species. We applied detergent to the olfactory organ and examined the effects on both morphology and function of the olfactory system in adult zebrafish....

journal_title：Neuroscience

authors： White EJ,Kounelis SK,Byrd-Jacobs CA

更新日期：2015-01-22 00:00:00

abstract：:Free intracellular calcium concentration ([Ca2+]in) was recorded at 22 degrees C by means of Indo-1 or Fura-2 single-cell microfluorometry in cultured dorsal root ganglion neurons obtained from neonatal rats. The resting [Ca2+]in in dorsal root ganglion neurons was 73 +/- 21 nM (mean +/- S.D., n = 94). Fast applicatio...

journal_title：Neuroscience

authors： Usachev Y,Shmigol A,Pronchuk N,Kostyuk P,Verkhratsky A

更新日期：1993-12-01 00:00:00

abstract：:We recorded the effects of hypoxia combined with relative hypoglycemia on pre- and post-synaptic potentials in the CA1 area of slices from 4-month-old control and diabetic (streptozotocin-treated) Wistar rats. In experiments on slices kept in 10 or 4 mM glucose (at 33 degrees C), hypoxia was applied until the pre-syna...

journal_title：Neuroscience

authors： Tekkök SB,Godfraind JM,Krnjević K

更新日期：2002-01-01 00:00:00

abstract：:The investigation on neurotransmission function during normal and pathologic development is a pivotal component needed to understand the basic mechanisms underlying neurodevelopmental pathologies. To study these diseases, many animal models have been generated which allowed to face the limited availability of human ti...

journal_title：Neuroscience

authors： Ruffolo G,Cifelli P,Miranda-Lourenço C,De Felice E,Limatola C,Sebastião AM,Diógenes MJ,Aronica E,Palma E

更新日期：2020-07-15 00:00:00

abstract：:Latent inhibition, the process whereby pre-exposure to a conditioned stimulus without consequence impairs subsequent learning of an association between the conditioned stimulus and an unconditioned stimulus, is reportedly disrupted in both amphetamine-treated rats and in acute schizophrenics. This has led to the sugge...

journal_title：Neuroscience

authors： Murphy CA,Pezze M,Feldon J,Heidbreder C

更新日期：2000-01-01 00:00:00

abstract：:This paper presents results obtained from experiments performed on two behaving monkeys (Macaca mulatta) viewing correlated and uncorrelated dynamic random dot stereograms. Extracellular single unit activity was recorded from areas V1 and V2. We found that cells sensitive to correlated stereograms (38%) were also sens...

journal_title：Neuroscience

authors： Gonzalez F,Krause F,Perez R,Alonso JM,Acuña C

更新日期：1993-02-01 00:00:00

abstract：:The expression of the messenger RNAs encoding N-methyl-D-aspartate receptor subunits in neurologically normal post-mortem human brain was studied by in situ hybridization. In the caudate, putamen and nucleus accumbens strong hybridization signals were observed for N-methyl-D-aspartate R1-1 messenger RNA but much weake...

journal_title：Neuroscience

authors： Rigby M,Le Bourdellès B,Heavens RP,Kelly S,Smith D,Butler A,Hammans R,Hills R,Xuereb JH,Hill RG,Whiting PJ,Sirinathsinghji DJ

更新日期：1996-07-01 00:00:00

abstract：:Chronic restraint stress produces morphological changes in medial prefrontal cortex and disrupts a prefrontally mediated behavior, retrieval of extinction. To assess potential physiological correlates of these alterations, we compared neural activity in infralimbic and prelimbic cortex of unstressed versus stressed ra...

journal_title：Neuroscience

authors： Wilber AA,Walker AG,Southwood CJ,Farrell MR,Lin GL,Rebec GV,Wellman CL

更新日期：2011-02-03 00:00:00

abstract：:The human brain is composed of complex networks of 100 billion neurons that underlie its higher functions. The set of neural connections in the brain has recently attracted growing interest from the scientific community. It is important to identify individual differences in these neural connections to study the backgr...

journal_title：Neuroscience

authors： Takao H,Hayashi N,Ohtomo K

更新日期：2015-08-20 00:00:00

abstract：OBJECTIVE:Women are more prone to major depressive disorders (MDDs) and the incidence of MDD in women is almost twice that of men. Insular cortex abnormalities are a common finding in neuroanatomical studies of patients with MDD. However, it remains largely unclear whether female MDD patients at different clinical stag...

journal_title：Neuroscience

authors： Liu CH,Jing B,Ma X,Xu PF,Zhang Y,Li F,Wang YP,Tang LR,Wang YJ,Li HY,Wang CY

更新日期：2014-03-14 00:00:00

abstract：:Tau hyperphosphorylation leads to formation of paired helical filament/neurofibrillary tangles, the hallmark lesion seen in Alzheimer's disease (AD) brain. An imbalanced regulation in protein kinases and protein phosphatases in the affected neurons is proposed to be a reasonable causative factor to the disease process...

journal_title：Neuroscience

authors： Sun L,Liu SY,Zhou XW,Wang XC,Liu R,Wang Q,Wang JZ

更新日期：2003-01-01 00:00:00

abstract：:The administration of methamphetamine (METH, 10 mg/kg, i.p.) to male ICR mice induced stereotyped behavior consisting of nail and/or wood chip biting (86.0%), continuous sniffing (12.0%), head bobbing (1.1%), and circling (1.0%) during the observation period of 1 h. Pretreatment of the mice with metoprine (2, 10, and ...

journal_title：Neuroscience

authors： Kitanaka J,Kitanaka N,Tatsuta T,Morita Y,Takemura M

更新日期：2007-07-13 00:00:00

abstract：:Non-synaptic transmission is pervasive throughout the nervous system. It appears especially prevalent in peripheral ganglia, where non-synaptic interactions between neighboring cell bodies have been described in both physiological and pathological conditions, a phenomenon referred to as cross-depolarization (CD) and t...

journal_title：Neuroscience

authors： Carvalho GB,Mulpuri Y,Damasio A,Spigelman I

更新日期：2019-12-15 00:00:00

abstract：:The enkephalin-like immunoreactivity in the retina of chicks has been studied using immunohistochemical and radioimmunoassay techniques. The histochemical experiments showed that the immunoreactivity was confined to a subpopulation of amacrine cells in the inner nuclear layer which projected processes into sublaminae ...

journal_title：Neuroscience

authors： Millar TJ,Salipan N,Oliver JO,Morgan IG,Chubb IW

更新日期：1984-09-01 00:00:00

abstract：:Neural injury triggers changes in the expression of a large number of gene families. Particularly interesting are those encoding proteins involved in the generation, propagation or restoration of electric potentials. The expression of the Na+, K+-ATPase subunit isoforms (alpha, beta and gamma) was studied in dorsal ro...

journal_title：Neuroscience

authors： Arteaga MF,Gutiérrez R,Avila J,Mobasheri A,Díaz-Flores L,Martín-Vasallo P

更新日期：2004-01-01 00:00:00

abstract：:To define mechanisms underlying neurovascular injury following brain embolism-induced neurodegeneration, we investigated temporal and spatial pathological changes in brain microvessels up to 12 weeks after microsphere embolism (ME) induction in aged male rats. Mild ME upregulated endothelial nitric oxide synthase (eNO...

journal_title：Neuroscience

authors： Han F,Ali Raie A,Shioda N,Qin ZH,Fukunaga K

更新日期：2008-05-02 00:00:00

abstract：:The effects of steroid hormones on glutamate neurotoxicity were examined in cultured spinal cord neurons. The extent of neuronal damage, produced by glutamate exposure for 15 min, was estimated based on the activity of lactate dehydrogenase released from degenerated neurons to the media during 24 h of post-exposure in...

journal_title：Neuroscience

authors： Ogata T,Nakamura Y,Tsuji K,Shibata T,Kataoka K

更新日期：1993-07-01 00:00:00

abstract：:Auditory-visual (AV) events often involve a leading visual cue (e.g. auditory-visual speech) that allows the perceiver to generate predictions about the upcoming auditory event. Electrophysiological evidence suggests that when an auditory event is predicted, processing is sped up, i.e., the N1 component of the ERP occ...

journal_title：Neuroscience

authors： Paris T,Kim J,Davis C

更新日期：2017-02-20 00:00:00

abstract：:Significant alterations in glutamatergic neurotransmission have been reported in major depressive disorder (MDD) that could underlie psychiatric traits. Studies were mainly interested in synaptic dysfunction in the prefrontal cortex, a key structure involved in depressive-like behavior, however hippocampus has been sh...

journal_title：Neuroscience

authors： Dutar P,Tolle V,Kervern M,Carcenac C,Carola V,Gross C,Savasta M,Darmon M,Masson J

更新日期：2019-01-01 00:00:00

abstract：:Professional Pingju actors have been shown to exhibit practice-induced plastic changes in spontaneous regional brain activity; however, whether these changes are present in resting-state regional cerebral blood flow (CBF) remains largely unclear. Here, twenty professional Pingju opera actors and 20 age-, sex-, and han...

journal_title：Neuroscience

authors： Zhao F,Zhang W,Zhu D,Wang X,Qin W,Liu F

更新日期：2020-06-01 00:00:00