Abstract:
PURPOSE:Although a role of glycemic index (GI) and glycemic load (GL) in age-related cataract development is plausible, a few studies, all conducted in USA or Australia, provided results on this issue. The aim of the present study was to provide new original data from a Mediterranean population. METHODS:We analyzed data from an Italian case-control study including 761 cases with cataract extraction and 1,522 hospital controls, frequency-matched with cases by center, sex, and age. Multivariate odds ratios (ORs) for GI and GL intakes were obtained from logistic regression models after allowance for major confounding factors, including non carbohydrate energy intake, smoking, and diabetes. RESULTS:The ORs of cataract extraction for the highest versus the lowest tertile were 1.20 (95% confidence interval, CI 0.91-1.57) for GI and 1.57 (95% CI 1.16-2.13) for GL, with a statistically significant trend in risk for GL (p < 0.01). Results were materially unchanged when diabetics were excluded from the analysis. No heterogeneity emerged across strata of sex, age, education, smoking habits and body mass index. CONCLUSIONS:The present study supports a positive association between dietary GL and the risk of cataract extraction, independently from diabetes, and a lack of association for GI.
journal_name
Eur J Nutrjournal_title
European journal of nutritionauthors
Turati F,Filomeno M,Galeone C,Serraino D,Bidoli E,La Vecchia Cdoi
10.1007/s00394-014-0731-ysubject
Has Abstractpub_date
2015-04-01 00:00:00pages
475-81issue
3eissn
1436-6207issn
1436-6215journal_volume
54pub_type
杂志文章,多中心研究abstract:PURPOSE:It is thought that total energy intake in women is increased during the luteal versus follicular phase of the menstrual cycle; however, less is understood regarding changes in diet composition (i.e., macro- and micronutrient intakes) across the cycle. The aim of this study was to investigate changes in macronut...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-015-0931-0
更新日期:2016-04-01 00:00:00
abstract:BACKGROUND:Conifer seeds are used for food preparation in several countries. Aim of the study To assess the lipid-lowering and antiatherogenic properties of maritime pine (Pinuspinaster) seed oil. METHODS:The effects of maritime pine oil supplementation (20% w/w) for 2 weeks were compared to those of coconut and sunfl...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s394-001-8355-6
更新日期:2001-12-01 00:00:00
abstract:PURPOSE:To test the effect of three diets in their ability to sustain weight loss and improve type 2 diabetes (T2D) and cardiovascular disease (CVD) risk markers after 18-month intervention. METHODS:Following a ≥8 % weight loss, 131 healthy, overweight/obese (BMI ± SD 31.5 ± 2.6 kg/m2) men (n = 55) and women (n = 76) ...
journal_title:European journal of nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00394-015-1116-6
更新日期:2017-03-01 00:00:00
abstract:BACKGROUND:The imbalance of n-6 and n-3 polyunsaturated fatty acids in the maternal diet impairs intestinal barrier development and sensitizes the colon response to inflammatory insults in the young rats. With a view to overcoming this issue, we designed this study to investigate the effect of maternal and neonatal int...
journal_title:European journal of nutrition
pub_type: 杂志文章
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更新日期:2016-08-01 00:00:00
abstract:INTRODUCTION:There is growing evidence that a diet low in fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAP) improves symptoms in irritable bowel syndrome (IBS) patients. We aimed to retrospectively investigate the effects of this diet in Irish IBS cohort over a 12-month follow-up period...
journal_title:European journal of nutrition
pub_type: 杂志文章
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abstract:PURPOSE:Previous evidence for the associations of eating frequency and food consumption with clustering of metabolic risk factors among children is limited. We therefore investigated association of the daily number of main meals and snacks and food consumption with a metabolic risk score and individual metabolic risk f...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-013-0646-z
更新日期:2014-09-01 00:00:00
abstract:PURPOSE:This study was aimed to determine the impact of hydroxytyrosol (HT), a minor compound found in olive oil, on breast cancer stem cells (BCSCs) and the migration capacity of triple-negative breast cancer (TNBC) cell lines through the alteration of epithelial-to-mesenchymal transition (EMT) and embryonic signaling...
journal_title:European journal of nutrition
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更新日期:2019-12-01 00:00:00
abstract:PURPOSE:Impaired B vitamin status has been identified as a risk factor for major chronic diseases. This study aims at examining the determinants of plasma folate and vitamin B12 concentrations, considering lifestyle factors and MTHFR polymorphisms. METHODS:A total of 988 women aged 40-65 years from the French E3N coho...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-016-1365-z
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abstract::The purpose of this review was to systematically evaluate the variability of the fatty acid composition of venous cord blood phospholipids in different populations. In an attempt to review published evidence systematically, we found 19 data sets describing fatty acid composition of venous cord blood phospholipids in 1...
journal_title:European journal of nutrition
pub_type: 杂志文章,评审
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更新日期:2002-06-01 00:00:00
abstract:BACKGROUND:Mediterranean diet (MED) is associated with health benefits, yet scarce data exist regarding the role of MED in inflammatory bowel diseases (IBD). Herein, we aimed to evaluate the association between MED and inflammatory markers in patients with IBD after pouch surgery. METHODS:Consecutive patients after po...
journal_title:European journal of nutrition
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abstract:PURPOSE:In vitro and in vivo studies suggested that flavonols, flavones, flavanones and flavan-3-ols have preventive effects on breast carcinogenesis. Epidemiological evidence about the associations between these flavonoid biomarkers and breast cancer risk is limited. This study aimed to investigate the association bet...
journal_title:European journal of nutrition
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更新日期:2020-07-18 00:00:00
abstract:PURPOSE:Evidence of an association between n-3 polyunsaturated fatty acids (PUFAs) and metabolic syndrome (MS) is limited and inconsistent. We investigated the association between n-3 PUFAs in erythrocytes and the presence of MS in Chinese adults. METHODS:The levels of α-linolenic acid (ALA), eicosapentaenoic acid (EP...
journal_title:European journal of nutrition
pub_type: 杂志文章
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journal_title:European journal of nutrition
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doi:10.1007/s00394-018-1883-y
更新日期:2020-02-01 00:00:00
abstract:PURPOSE:The optimal health benefits of curcumin are limited by its low solubility in water and corresponding poor intestinal absorption. Cyclodextrins (CD) can form inclusion complexes on a molecular basis with lipophilic compounds, thereby improving aqueous solubility, dispersibility, and absorption. In this study, we...
journal_title:European journal of nutrition
pub_type: 临床试验,杂志文章,随机对照试验
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journal_title:European journal of nutrition
pub_type: 杂志文章
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更新日期:2018-09-01 00:00:00
abstract:PURPOSE:Heme iron may contribute to the development of atherosclerosis by catalyzing production of hydroxyl-free radicals and promoting low-density lipoprotein oxidation. However, epidemiologic findings regarding the association between heme iron intake and risk of coronary heart disease (CHD) are inconsistent. We aime...
journal_title:European journal of nutrition
pub_type: 杂志文章,meta分析
doi:10.1007/s00394-013-0535-5
更新日期:2014-01-01 00:00:00
abstract:INTRODUCTION:The influence of sex and gender is particularly relevant in cardiovascular diseases (CVD) as well as in several aspects of drug pharmacodynamics and pharmacokinetics. Anatomical and physiological differences between the sexes may influence the activity of many drugs, including the possibility of their inte...
journal_title:European journal of nutrition
pub_type: 杂志文章,评审
doi:10.1007/s00394-018-1695-0
更新日期:2018-12-01 00:00:00
abstract:BACKGROUND:While a relationship between alcohol and cardiovascular risk factors is well established, data suggest that the type of alcoholic beverage could modulate this relationship. AIM OF THE STUDY:To determine whether drinking patterns modulate the relationship between alcohol and cardiovascular risk factors. MET...
journal_title:European journal of nutrition
pub_type: 杂志文章
doi:10.1007/s00394-005-0567-6
更新日期:2006-03-01 00:00:00
abstract:PURPOSE:This project sought to test the role of diet-related inflammation in modulating the risk of oesophageal cancer. METHODS:A nationwide population-based case-control study was conducted from 1 December 1994 through 31 December 1997 in Sweden. All newly diagnosed patients with adenocarcinoma of the oesophagus or g...
journal_title:European journal of nutrition
pub_type: 杂志文章
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abstract:BACKGROUND AND AIMS:Lipid peroxidation is believed to be involved in the pathophysiology of a number of diseases and in the process of aging. This study investigates the effects of dietary supplementation with vitamin E (20 g/kg diet of all-rac-alpha-tocopheryl succinate for 3 weeks) on both non-enzymatic and enzymatic...
journal_title:European journal of nutrition
pub_type: 杂志文章
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journal_title:European journal of nutrition
pub_type: 杂志文章,随机对照试验
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更新日期:2009-04-01 00:00:00
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journal_title:European journal of nutrition
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abstract:PURPOSE:Increasing evidence suggests the potential use of natural antioxidant compounds in the prevention/treatment of osteoporosis. This study was undertaken to investigate the effects of purified delphinidin-3-rutinoside (D3R), isolated from Solanum melongena L., on osteoblast viability and differentiation in basal c...
journal_title:European journal of nutrition
pub_type: 杂志文章
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更新日期:2019-04-01 00:00:00
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journal_title:European journal of nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00394-015-1110-z
更新日期:2017-03-01 00:00:00
abstract:PURPOSE:Pregnancy is characterised by increased bone turnover, but high bone turnover with resorption exceeding formation may lead to negative maternal bone remodelling. Recent studies are conflicting regarding the effect of calcium on skeletal health in pregnancy. The aim of this study was to examine the seasonal effe...
journal_title:European journal of nutrition
pub_type: 杂志文章
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更新日期:2018-04-01 00:00:00
abstract:PURPOSE:Several studies in recent years have investigated the relationship between alcohol intake and melanoma risk, with conflicting results. To help clarify this issue, we conducted a literature review and dose-response meta-analysis of studies published until June 30th, 2017, that examined the association between al...
journal_title:European journal of nutrition
pub_type: 杂志文章,meta分析
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更新日期:2018-10-01 00:00:00
abstract:PURPOSE:Introduction of complementary food usually leads to decreasing intakes of long-chain n-3 polyunsaturated fatty acids (n-3 LC-PUFA), compared to full breastfeeding. In the randomised controlled PINGU intervention trial, we tested the effects of complementary foods with different contents of alpha-linolenic acid ...
journal_title:European journal of nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00394-015-0982-2
更新日期:2016-06-01 00:00:00
abstract:PURPOSE:Critically low skeletal muscle mass and strength, observed in 20% of people with chronic heart failure (CHF), reduces functional capacity, quality of life (QoL) and survival. Protein and essential amino acid (EAA) supplementation could be a viable treatment strategy to prevent declines in muscle strength and pe...
journal_title:European journal of nutrition
pub_type: 杂志文章,评审
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abstract:PURPOSE:Our aim was to characterize the effect of an unfamiliar high-fat diet (HFD) on circadian feeding behaviour, plasma parameters, body weight (BW), and gene expression in the prefrontal cortex (PFC) of adolescent male mice. To this end, mice were allowed to consume a HFD during 48 h, but one group was allowed a fr...
journal_title:European journal of nutrition
pub_type: 杂志文章
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更新日期:2017-08-01 00:00:00
abstract:PURPOSE:The enzymes encoded by fatty acid desaturases (FADS) genes determine the desaturation of long-chain polyunsaturated fatty acids (LCPUFA). We investigated if haplotype and single nucleotide polymorphisms (SNPs) in FADS gene cluster can influence LCPUFA status in infants who received either fish oil or placebo su...
journal_title:European journal of nutrition
pub_type: 杂志文章,随机对照试验
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更新日期:2018-10-01 00:00:00