Abstract：
PURPOSE:Evidence of an association between n-3 polyunsaturated fatty acids (PUFAs) and metabolic syndrome (MS) is limited and inconsistent. We investigated the association between n-3 PUFAs in erythrocytes and the presence of MS in Chinese adults. METHODS:The levels of α-linolenic acid (ALA), eicosapentaenoic acid (EPA), docosapentaenoic acid (DPA), and docosahexaenoic acid (DHA) in erythrocytes were measured using gas chromatography in 3072 participants (900 men and 2172 women) aged 30-75 years from Guangzhou, China. Cardiometabolic factors were determined, and MS was defined using the updated Adult Treatment Panel III criteria. Other covariates were collected via interviewer-administered questionnaires. RESULTS:After adjusting for age and other confounders, higher levels of marine-derived n-3 PUFAs, including EPA, DPA, and DHA, were associated with a lower presence of metabolic syndrome in both men and women. The odds ratios (95 % confidence interval) for MS obtained by comparing extreme quartiles were 0.55 (0.35-0.88) (EPA), 0.54 (0.34-0.87) (DPA), 0.45 (0.27-0.73) (DHA), and 0.52 (0.32-0.84) (total n-3 PUFAs) in men (p trend <0.05 for all results); and 0.74 (0.56-0.99) (EPA), 0.73 (0.55-0.98) (DPA), 0.75 (0.56-1.02) (DHA), and 0.71 (0.53-0.96) (total n-3 PUFAs) in women, respectively. No significant association of ALA with MS was observed (p trend > 0.05). CONCLUSION:Higher levels of total n-3 PUFAs, EPA, DPA, and DHA, but not of ALA, in erythrocyte membranes are associated with a lower presence of metabolic syndrome in Chinese adults.
journal_name
Eur J Nutrjournal_title
European journal of nutritionauthors
Dai XW,Chen YM,Zeng FF,Sun LL,Chen CG,Su YXdoi
10.1007/s00394-015-0912-3subject
Has Abstractpub_date
2016-04-01 00:00:00pages
981-9issue
3eissn
1436-6207issn
1436-6215pii
10.1007/s00394-015-0912-3journal_volume
55pub_type
杂志文章abstract：BACKGROUND:Grapes and wine contain high concentrations of polyphenolic compounds. Although their cancer protective effect has been well documented, their activity as anticarcinogens should be cautiously considered since the molecular bases of action and their applicability to human cancer prevention are still unclear. ...
journal_title：European journal of nutrition
pub_type： 杂志文章
doi：10.1007/s00394-003-0398-2
更新日期：2003-01-01 00:00:00
abstract：PURPOSE:Several studies have demonstrated the properties of hydroxytyrosol, a phenolic compound present in olive oils and olives with a well-characterized impact on human health. Nevertheless, some knowledge gaps remain on its bioavailability and metabolism; overall concerning to the real rate per cent of absorption an...
journal_title：European journal of nutrition
pub_type： 杂志文章
doi：10.1007/s00394-020-02295-0
更新日期：2020-06-10 00:00:00
abstract：BACKGROUND:Iodine fortification programs have been applied in many iodine deficient regions. Iodine excess is also unfavourable, and it is recommended to monitor iodine status by measuring urinary iodine concentration (UIC). The number of samples needed in such monitoring depends on the variation in UIC. However, it is...
journal_title：European journal of nutrition
pub_type： 杂志文章
doi：10.1007/s00394-013-0551-5
更新日期：2014-01-01 00:00:00
abstract：BACKGROUND:Docosahexaenoic (C22:6) and arachidonic acid (C20:4) are long-chain polyunsaturated fatty acids (LC-PUFA), essential to fetal development, and preferentially transported by plasma phospholipids. OBJECTIVE:To characterize fetal and maternal plasma phospholipid changes during gestation, and to investigate whe...
journal_title：European journal of nutrition
pub_type： 杂志文章
doi：10.1007/s00394-015-1036-5
更新日期：2016-10-01 00:00:00
abstract：PURPOSE:To provide a new and efficient at-the-toilet-bowl method of self-assessing urine concentration via urine color (Uc) to identify hypohydration. METHODS:A large athletic population (n = 189) delivered a urine sample, then chose a color panel that was displayed on the back wall of the lavatory stall. Selection wa...
journal_title：European journal of nutrition
pub_type： 杂志文章
doi：10.1007/s00394-020-02460-5
更新日期：2021-01-08 00:00:00
abstract：PURPOSE:Inadequate iodine intake may result in iodine deficiency disorders (IDD). Thus, for more than 50 years, policies for the regulation of salt fortification with iodine have existed in Brazil. In 2003, a study on 6-14-year-old schoolchildren from regions of the state of São Paulo showed a median urinary iodine con...
journal_title：European journal of nutrition
pub_type： 杂志文章
doi：10.1007/s00394-011-0239-7
更新日期：2012-08-01 00:00:00
abstract：PURPOSE:Rebalancing the contribution of animal- and plant-based foods is needed to achieve sustainable diet. However, little is known concerning individual characteristics that may influence intake of plant-based foods and their changes over time. We aimed to assess changes in the contribution of plant-based foods to d...
journal_title：European journal of nutrition
pub_type： 杂志文章
doi：10.1007/s00394-018-1752-8
更新日期：2019-08-01 00:00:00
abstract：BACKGROUND AND AIMS:Lipid peroxidation is believed to be involved in the pathophysiology of a number of diseases and in the process of aging. This study investigates the effects of dietary supplementation with vitamin E (20 g/kg diet of all-rac-alpha-tocopheryl succinate for 3 weeks) on both non-enzymatic and enzymatic...
journal_title：European journal of nutrition
pub_type： 杂志文章
doi：10.1007/pl00007381
更新日期：2001-02-01 00:00:00
abstract：BACKGROUND:Mediterranean diet (MED) is associated with health benefits, yet scarce data exist regarding the role of MED in inflammatory bowel diseases (IBD). Herein, we aimed to evaluate the association between MED and inflammatory markers in patients with IBD after pouch surgery. METHODS:Consecutive patients after po...
journal_title：European journal of nutrition
pub_type： 杂志文章
doi：10.1007/s00394-019-02158-3
更新日期：2020-10-01 00:00:00
abstract：:In domestic animals, acid-base balance may be influenced by nutrition. The major research effort in this area has been made on the prevention of hypocalcemic postparturient paresis in dairy cows. This disorder is caused by the sudden increase of calcium secretion into the colostrum. The manipulation of the dietary cat...
journal_title：European journal of nutrition
pub_type： 杂志文章,评审
doi：10.1007/s394-001-8352-2
更新日期：2001-10-01 00:00:00
abstract：PURPOSE:It is believed that breakfast is an important meal due to its effect on appetite control and cognitive performance, yet little evidence exists to support this hypothesis. METHODS:Using a crossover design, 33 healthy undergraduates (aged 22 ± 2 years with a BMI of 23.5 ± 1.7 kg/m2) were randomized one of four b...
journal_title：European journal of nutrition
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00394-016-1254-5
更新日期：2017-09-01 00:00:00
abstract：PURPOSE:We investigated effects of ground whole flaxseed supplementation on erythrocyte polyunsaturated fatty acids (PUFAs) and serum biomarkers of inflammation, endothelial dysfunction, oxidative stress, and thrombosis in Chinese with risk factors of metabolic syndrome (MetS). METHODS:This study was a secondary analy...
journal_title：European journal of nutrition
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00394-012-0461-y
更新日期：2013-08-01 00:00:00
abstract：BACKGROUND:Bioavailability of fat-soluble vitamins from conventional oral supplements is insufficient in some conditions in which fat digestion and absorption are chronically impaired (e. g. cystic fibrosis). AIM OF THE STUDY:We used a water-soluble form of fatsoluble vitamin E (AQUANOVA solubilisate) to create a nutr...
journal_title：European journal of nutrition
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00394-005-0556-9
更新日期：2006-02-01 00:00:00
abstract：PURPOSE:To explore whether changes in dietary protein sources can lower plasma branched-chain amino acids (BCAAs), aromatic amino acids and sulfur amino acids (SAAs) that are often elevated in the obese, insulin-resistant state and in type 2 diabetes. METHODS:Thirty-six subjects (mean age 31 ± 2 years) underwent a vol...
journal_title：European journal of nutrition
pub_type： 杂志文章
doi：10.1007/s00394-016-1237-6
更新日期：2017-08-01 00:00:00
abstract：BACKGROUND:While naturally occurring inulin has anti-hyperlipidemic effects in animals and humans, health effects of synthetic inulin with different degrees of fructose polymerization remain poorly understood. AIM OF THE STUDY:Our study aimed at distinguishing health effects of synthetic inulin with different degrees ...
journal_title：European journal of nutrition
pub_type： 杂志文章
doi：10.1007/s00394-008-0713-z
更新日期：2008-06-01 00:00:00
abstract：INTRODUCTION:The influence of sex and gender is particularly relevant in cardiovascular diseases (CVD) as well as in several aspects of drug pharmacodynamics and pharmacokinetics. Anatomical and physiological differences between the sexes may influence the activity of many drugs, including the possibility of their inte...
journal_title：European journal of nutrition
pub_type： 杂志文章,评审
doi：10.1007/s00394-018-1695-0
更新日期：2018-12-01 00:00:00
abstract：PURPOSE:Poor sperm quality is a major contributor to infertility in heterosexual couples, but at present there are few empirical therapies. Several studies have examined the role of dietary factors and data from randomized controlled trials suggest that oral antioxidant therapy can improve some sperm parameters. Health...
journal_title：European journal of nutrition
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00394-019-02091-5
更新日期：2020-03-01 00:00:00
abstract：PURPOSE:Considerable variation in 25-hydroxyvitamin D (25(OH)D) in populations worldwide that seems to be independent of latitude has been reported. Therefore, we aimed to assess vitamin D status of a mid-aged German general population and to identify its dietary, lifestyle, anthropometric, and genetic determinants. M...
journal_title：European journal of nutrition
pub_type： 杂志文章
doi：10.1007/s00394-013-0577-8
更新日期：2014-04-01 00:00:00
abstract：PURPOSE:Higher long-chain polyunsaturated fatty acids (LCP) in infant compared with maternal lipids at delivery is named biomagnification. The decline of infant and maternal docosahexaenoic acid (DHA) status during lactation in Western countries suggests maternal depletion. We investigated whether biomagnification pers...
journal_title：European journal of nutrition
pub_type： 杂志文章
doi：10.1007/s00394-011-0245-9
更新日期：2012-09-01 00:00:00
abstract：PURPOSE:Dietary polyphenols have been studied for their potential effects on metabolic disorders, but studies on risk of hypertension are scarce. This study aimed to test the association between total and individual classes of dietary polyphenols and incidence of hypertension in the Polish arm of the Health, Alcohol an...
journal_title：European journal of nutrition
pub_type： 杂志文章
doi：10.1007/s00394-017-1438-7
更新日期：2018-06-01 00:00:00
abstract：PURPOSE:A meal replacement may be an effective strategy in the management of obesity to increase antioxidant intake, attenuating oxidative stress and inflammation. In the present study, we investigated the efficacy of a new nutritional supplement to reduce metabolic risk parameters in obese women. METHODS:In a randomi...
journal_title：European journal of nutrition
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/s00394-013-0598-3
更新日期：2014-04-01 00:00:00
abstract：PURPOSE:Protein-restricted diet during pregnancy is related to oxidative stress and, as a consequence, damage to nephrogenesis. We investigated the effects of vinifera grape skin extract (ACH09)-derived polyphenols on preserving renal morphology of maternal protein-restricted 1-day-old offspring. METHODS:Female C57/Bl...
journal_title：European journal of nutrition
pub_type： 杂志文章
doi：10.1007/s00394-015-0963-5
更新日期：2016-06-01 00:00:00
abstract：PURPOSE:The impact of diet on endurance performance and cognitive function has been extensively researched in controlled settings, but there are limited observational data in field situations. This study examines relationships between nutrient intake and cognitive function following endurance exercise amongst a group o...
journal_title：European journal of nutrition
pub_type： 杂志文章
doi：10.1007/s00394-012-0364-y
更新日期：2013-03-01 00:00:00
abstract：PURPOSE:The interaction between genetics and diet may explain the present disagreement in the protective role of vitamin intake on cardiovascular disease. We cross-sectionally assessed the interaction of habitual dietary intake of β-carotene, vitamin C, folate, and vitamin E with single nucleotide polymorphisms (SNPs) ...
journal_title：European journal of nutrition
pub_type： 杂志文章,多中心研究
doi：10.1007/s00394-015-0896-z
更新日期：2016-03-01 00:00:00
abstract：PURPOSE:Laboratory studies have suggested that vitamin D inadequacy may be implicated in development of hypertension. Evidence from epidemiologic studies remains limited. We aim to examine the prospective associations of circulating vitamin D metabolites, vitamin D receptor (VDR) gene polymorphisms, and their interacti...
journal_title：European journal of nutrition
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00394-012-0480-8
更新日期：2013-10-01 00:00:00
abstract：PURPOSE:In obesity and diabetes the liver is highly susceptible to abnormal uptake and storage of fat. In certain individuals hepatic steatosis predisposes to the development of non-alcoholic steatohepatitis (NASH), a disease marked by hepatic inflammation and fibrosis. Although the precise pathophysiology of NASH is u...
journal_title：European journal of nutrition
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00394-018-1721-2
更新日期：2019-06-01 00:00:00
abstract：BACKGROUND:To investigate whether a low meat content of complementary food as accepted by EU law increases the risk of well-nourished infants to develop iron deficiency during the complementary feeding period. METHODS:Term born, healthy infants were randomized into a 'High Meat' Group (HM, n = 48) receiving commercial...
journal_title：European journal of nutrition
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00394-009-0043-9
更新日期：2010-02-01 00:00:00
abstract：PURPOSE:Type 2 diabetes mellitus (T2DM) is characterized by both impaired pancreatic β-cell function (BCF) and insulin resistance. In the etiology of T2DM, BCF basically determines whether a person with a certain degree of insulin resistance develops T2DM, as β-cells are able to compensatorily increase insulin secretio...
journal_title：European journal of nutrition
pub_type： 杂志文章
doi：10.1007/s00394-018-1644-y
更新日期：2019-03-01 00:00:00
abstract：PURPOSE:L-Theanine is the major free amino acid present in tea (Camellia sinensis L.). The effects of several tea constituents on male reproduction have been investigated, but L-theanine has been overlooked. Sertoli cells (SCs) are essential for the physical and nutritional support of germ cells. In this study, we aime...
journal_title：European journal of nutrition
pub_type： 杂志文章
doi：10.1007/s00394-019-01999-2
更新日期：2019-10-01 00:00:00
abstract：BACKGROUND:At the present time the recommended daily intake or allowance (RDA) and the safe upper level (UL) of intake of micronutrients are given as single values. The recommended daily intake is considered to cover the requirements of 97.5% of the population while the safe upper level is a value for the whole populat...
journal_title：European journal of nutrition
pub_type： 杂志文章
doi：10.1007/s00394-007-0691-6
更新日期：2008-02-01 00:00:00
