The radioprotective effect of Nigella sativa on nitrosative stress in lens tissue in radiation-induced cataract in rat.

abstract：PURPOSE:To investigate the corneal toxicity of Xalatan and three latanoprost generics using transepithelial electrical resistance (TER) and scanning electron microscopy (SEM). METHODS:Corneal TER changes after a 60-s exposure to Xalatan (latanoprost 0.005% preserved with 0.02% BAC), and latanoprost generics (Latanopro...

journal_title：Cutaneous and ocular toxicology

authors： Uematsu M,Mohamed YH,Onizuka N,Ueki R,Inoue D,Fujikawa A,Sasaki H,Kitaoka T

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND/OBJECTIVE:Acne vulgaris is one of the most common diseases of the youth. Systemic isotretinoin is the only drug which acts on all of the etiopathogenic mechanisms of acne. Isotretinoin has some well-known side effects. Besides these, there is a suspicion whether it causes infertility or not. In this study, w...

journal_title：Cutaneous and ocular toxicology

authors： Çinar L,Kartal D,Ergin C,Aksoy H,Karadag MA,Aydin T,Cinar E,Borlu M

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:In our study, we aimed to show the effects of smoking on choroidal thickness and ocular pulse amplitude. It is known that the anatomy and physiologic functions of the choroid is important in ocular diseases like glaucoma and age-related macular degeneration. Choroidal thickness is measured by the spectral do...

journal_title：Cutaneous and ocular toxicology

authors： Dervişoğulları MS,Totan Y,Tenlik A,Yuce A

更新日期：2015-01-01 00:00:00

abstract：:Basal cell carcinoma (BCC), the most frequent malignant skin tumor observed in Caucasian adults, especially males, occurs mainly in sun-exposed areas of the body. BCC in the periungual tissues, such as proximal nail fold, nail matrix, nail bed and hyponychium, is rarely reported. We report a patient with two synchrono...

journal_title：Cutaneous and ocular toxicology

authors： Dika E,Patrizi A,Fanti PA,Alessandrini A,Sorci R,Piraccini BM,Vaccari S,Misciali C,Maibach HI

更新日期：2013-06-01 00:00:00

abstract：:A snakebite is a serious and important problem in tropical and subtropical cities. A vast majority of snakebites are nonvenomous. However, venomous snakebites may cause local tissue destruction, neuroparalysis, systemic hemorrhage, generalized myotoxicity, and acute renal failure. A 10-year-old boy was brought to the ...

journal_title：Cutaneous and ocular toxicology

authors： Ozkol HU,Karadag AS,Bilgili SG,Calka O

更新日期：2011-12-01 00:00:00

abstract：PURPOSES:To study the occurrence of ocular surface diseases on coal miners working under wells and to investigate the relation between xerophthalmia occurrence and coal dust contiguity. METHODS:To observe the influence of coal dust to ocular surface by using Schirmer to detect lacrimal gland secreting function, and br...

journal_title：Cutaneous and ocular toxicology

authors： Sun Z,Hong J,Yang D,Liu G

更新日期：2007-01-01 00:00:00

abstract：:Purpose: Pityriasis rosea (PR) is a common, self-limiting, inflammatory skin disease with an acute onset. The etiology of PR is not yet clearly known but the defect in the oxidation system involved in many papulosquamous skin diseases may play a role. Thiol/disulfide homeostasis is a new marker of oxidative stress and...

journal_title：Cutaneous and ocular toxicology

authors： Yüksel M,Ülfer G

更新日期：2019-12-01 00:00:00

abstract：:The most common adverse effects of oral isotretinoin (>1/10) are: cheilitis, skin dryness, erythema, itching, scaling, bruising, skin atopy, conjunctivitis, dry eyes and eyelid inflammation. The aim of this work was to define an optimal dose regime of the oral isotretinoin allowing for effective reduction of sebum pro...

journal_title：Cutaneous and ocular toxicology

authors： Bergler-Czop B,Brzezińska-Wcisło L

更新日期：2012-09-01 00:00:00

abstract：PURPOSE:To evaluate the treatment of autologous serum eye drops (ASED) on dry eyes in patients with graft-versus-host disease (GVHD). METHODS:A retrospective chart review of 35 patients with a history of ocular GVHD following hematopoietic stem cell transplantation that used ASED to alleviate dry eye symptoms was perf...

journal_title：Cutaneous and ocular toxicology

authors： Azari AA,Karadag R,Kanavi MR,Nehls S,Barney N,Kim K,Longo W,Hematti P,Juckett M

更新日期：2017-06-01 00:00:00

abstract：:The assessment of the potency of a skin sensitizing chemical is a key starting point for its subsequent risk assessment/management. The Local Lymph Node Assay can provide information on the relative skin sensitizing potency of contact allergens by interpolation from the dose response curve the concentration of a chemi...

journal_title：Cutaneous and ocular toxicology

authors： Ryan CA,Chaney JG,Gerberick GF,Kern PS,Dearman RJ,Kimber I,Basketter DA

更新日期：2007-01-01 00:00:00

abstract：:Attempts to improve formulation of topical products are a continuing process and the development of micro- and nanovesicular systems as well as polymeric microparticles has led to marketing of topical drugs and cosmetics using these technologies. Encapsulation of some well-known contact allergens in ethanolic liposome...

journal_title：Cutaneous and ocular toxicology

authors： Madsen JT,Vogel S,Johansen JD,Andersen KE

更新日期：2011-06-01 00:00:00

abstract：:A 56-year-old white woman developed a distinctive skin eruption over her mammary, lumbosacral, and pubic areas 2 weeks after the start of esomeprazole therapy for dyspeptic symptoms. Skin biopsy disclosed a spongiotic dermatitis with predominantly lymphocytic dermal infiltrate. Treatment with a tapering dose of cortic...

journal_title：Cutaneous and ocular toxicology

authors： Morais P,Baudrier T,Mota A,Cunha AP,Cadinha S,Barros AM,Azevedo F

更新日期：2010-09-01 00:00:00

abstract：:The skin is a major exposure route for many potentially toxic chemicals. It is, therefore, important to be able to predict the permeability of compounds through skin under a variety of conditions. Available skin permeability databases are often limited in scope and not conducive to developing effective models. This sp...

journal_title：Cutaneous and ocular toxicology

authors： Keshwani DR,Jones DD,Brand RM

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVE:To describe 8 cases of toxic keratopathy due to abuse of topical anesthetic drugs. METHODS:Clinical findings from patients with toxic keratopathy were investigated retrospectively. RESULTS:Two patients had toxic keratopathy bilaterally. Five of 8 patients had an ocular history of a corneal foreign body, 1 h...

journal_title：Cutaneous and ocular toxicology

authors： Yeniad B,Canturk S,Esin Ozdemir F,Alparslan N,Akarcay K

更新日期：2010-06-01 00:00:00

abstract：PURPOSE:To evaluate the effect of anti-tubercular treatment on retinal nerve fiber layer (RNFL) thickness and the efficiency of optic coherence tomography (OCT) on early diagnosis of optic neuropathy. METHODS:Twenty patients diagnosed with either pulmonary or extra-pulmonary tuberculosis which were treated with anti-t...

journal_title：Cutaneous and ocular toxicology

authors： Gümüş A,Öner V

更新日期：2015-01-01 00:00:00

abstract：:Skin patch testing of menses and venous blood on the vulva (labia majora) and the upper arm was performed to assess the potential contribution of these biological fluids to vulvar irritation during menstruation. After 24 and 48 hours of occlusive exposure, the skin of the labia majora was relatively unaffected by thes...

journal_title：Cutaneous and ocular toxicology

authors： Farage M,Warren R,Wang-Weigand S

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVE:To assess the incidence of seizures induced by cycloplegic ophthalmic drops. MATERIALS AND METHODS:A survey among members of the American Association for Pediatric Ophthalmology and Strabismus yielded five patients who received cycloplegic eye drops between 1998 and 2010 and who consequently developed a seiz...

journal_title：Cutaneous and ocular toxicology

authors： Wygnanski-Jaffe T,Nucci P,Goldchmit M,Mezer E

更新日期：2014-06-01 00:00:00

abstract：:The most common side effects of interferon-beta therapy following subcutaneous administration include pain, inflammation and induration at the injection site, which occur in approximately 20-60% of patients. Besides, transient injection-site erythema is frequently seen in beta-interferon therapy. Less frequent reactio...

journal_title：Cutaneous and ocular toxicology

authors： Ozuguz P,Kacar SD,Karaca S,Tokyol C

更新日期：2014-12-01 00:00:00

abstract：PURPOSE:The aim of this study was to determine the effects of single-dose intravitreal bevacizumab on the levels of vascular endothelial growth factor (VEGF) in serum and distant organs. METHODS:Adult New Zealand albino rabbits (n = 40) were divided into experimental and control groups. Experimental rabbits received a...

journal_title：Cutaneous and ocular toxicology

authors： Dınc E,Yıldırım O,Necat Yılmaz S,Canacankatan N,Ayaz L,Ozcan T,Temel GO

更新日期：2014-12-01 00:00:00

abstract：PURPOSE:The aim of this study was to evaluate and compare the toxicity of six different types of titanium dioxide (TiO2) nanoparticles (NP) on human epidermal keratinocytes (HEK). MATERIALS AND METHODS:Six TiO2 NP (A (10 nm), A*(32 nm), B (27.5 nm), C (200 nm), C*(30-40 nm), and D*(200-400 nm)) were suspended in water...

journal_title：Cutaneous and ocular toxicology

authors： Zhang LW,Monteiro-Riviere NA

更新日期：2019-03-01 00:00:00

abstract：:Psoriasis is a common skin disorder that needs a long-term management, not only because, of its prevalence but also because of the profound impact it can have on patients quality of life. Drugs may result in exacerbation of a preexisting psoriasis, in induction of psoriatic lesions on clinically uninvolved skin in pat...

journal_title：Cutaneous and ocular toxicology

authors： Dika E,Varotti C,Bardazzi F,Maibach HI

更新日期：2006-01-01 00:00:00

abstract：:Ciliary body is responsible for humour aqueous production in posterior chamber. Valproic acid (VPA) has been widely used for the treatment of epilepsy and other neuropsychiatric diseases such as bipolar disease and major depression. Oxcarbazepine (OXC) is a new anti-epileptic agent that has been used recently for chil...

journal_title：Cutaneous and ocular toxicology

authors： Göktaş G,Aktaş Z,Erdoğan D,Seymen CM,Karaca EE,Cansu A,Serdaroğlu A,Kaplanoğlu GT

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:The present cross-sectional study has the purpose to investigate the impact of aromatase inhibitors (AIs) on retinal nerve fiber layer (RNFL) thickness, optic nerve and macular function in patients using AIs for breast cancer treatment. METHODS:Participants in our study were 41 hormone-receptor-positive ear...

journal_title：Cutaneous and ocular toxicology

authors： Moschos MM,Chatziralli IP,Sergentanis T,Zagouri F,Chrysikos D,Ladas I,Zografos G

更新日期：2016-03-01 00:00:00

abstract：:In this report we present a case of erlotinib-induced trichomegaly in a male patient who received erlotinib for his pancreatic cancer. Trichomegaly as a side effect of epidermal growth factor receptor (EGFR) inhibitor therapy is uncommon in male patients. Also, it has not been reported previously in a patient with pan...

journal_title：Cutaneous and ocular toxicology

authors： Saif MW,Gnanaraj J

更新日期：2010-03-01 00:00:00

abstract：OBJECTIVE:To investigate the effects of topiramate on choroidal thickness and anterior chamber parameters using optical coherence tomography in the treatment of patients with migraine. METHODS:A total of 22 eyes of 22 adults (12 females, 10 males) diagnosed with migraine and scheduled to topiramate treatment for pain ...

journal_title：Cutaneous and ocular toxicology

authors： Gok M,Ozdemir O

更新日期：2017-12-01 00:00:00

abstract：:Context Incontinence-associated dermatitis (IAD) is a type of moisture-associated dermatitis caused by repeated skin exposure to urine or stool. A product that could mitigate such symptoms would have a significant impact on cost of care and patients' quality of life. Objective This study compared the clinical efficacy...

journal_title：Cutaneous and ocular toxicology

authors： Matar H,Larner J,Viegas V,Kansagra S,Atkinson KL,Shetage S,Skamarauskas JT,Theivendran B,Goldman VS,Chilcott RP

更新日期：2017-09-01 00:00:00

abstract：:The Organisation for Economic Co-operation and Development (OECD) Test Guideline 429 for the local lymph node assay (LLNA) indicates a minimum of 4 mice per dose group, or of 5 mice if statistics are required. Recent discussions at the Interagency Coordinating Committee for the Validation of Alternative Methods (ICCVA...

journal_title：Cutaneous and ocular toxicology

authors： Basketter DA,Dearman RJ,Kimber I,Gerberick GF,Ryan CA

更新日期：2009-01-01 00:00:00

abstract：INTRODUCTION:Sulfur mustard (SM) has been used as a dangerous chemical warfare agent since the early 20th century. Although many descriptive studies about SM-induced ocular injuries are present in the medical literature, few of them have been conducted over a large group with serious ocular involvement. MATERIALS AND ...

journal_title：Cutaneous and ocular toxicology

authors： Ghasemi H,Ghazanfari T,Ghassemi-Broumand M,Javadi MA,Babaei M,Soroush MR,Yaraee R,Faghihzadeh S,Poorfarzam S,Owlia P,Naghizadeh MM,Etezad-Razavi M,Jadidi K,Naderi M,Hassan ZM

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Hydrofluoric acid (HF) is a small and partially dissociated acid (pK(a) 3.2), able to deeply penetrate into human skin in addition to the corrosiveness of the hydrogen ion (H(+)) and the toxicity of the fluoride ion (F(-)). However, there has been a lack of experimental studies to objectively characterize th...

journal_title：Cutaneous and ocular toxicology

authors： Burgher F,Mathieu L,Lati E,Gasser P,Peno-Mazzarino L,Blomet J,Hall AH,Maibach HI

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:There is increasing interest in minimally invasive skin sampling techniques to assay markers of molecular biology and biochemical processes. OBJECTIVE:This overview examines methodology strengths and limitations, and exciting developments pending in the scientific community. MATERIALS AND METHODS:Publicati...

journal_title：Cutaneous and ocular toxicology

authors： Wang CY,Maibach HI

更新日期：2011-03-01 00:00:00