The impact of LLNA group size on the identification and potency classification of skin sensitizers: a review of published data.

abstract：BACKGROUND:Hydrofluoric acid (HF) is a small and partially dissociated acid (pK(a) 3.2), able to deeply penetrate into human skin in addition to the corrosiveness of the hydrogen ion (H(+)) and the toxicity of the fluoride ion (F(-)). However, there has been a lack of experimental studies to objectively characterize th...

journal_title：Cutaneous and ocular toxicology

authors： Burgher F,Mathieu L,Lati E,Gasser P,Peno-Mazzarino L,Blomet J,Hall AH,Maibach HI

更新日期：2011-06-01 00:00:00

abstract：PURPOSE:The aim of this study is to evaluate the effect of early amniotic membrane transplantation (AMT) in patients with topical proparacaine-related toxic keratopathy. MATERIALS AND METHODS:Between 2008 and 2011, eight eyes of seven patients with toxic keratopathy related to 0.5% proparacaine abuse underwent early A...

journal_title：Cutaneous and ocular toxicology

authors： Burcu A,Dogan E,Yalniz-Akkaya Z,Ornek F

更新日期：2013-09-01 00:00:00

abstract：:Drug-induced lichen planus has been induced by antibiotics, anticonvulsants, antidiabetics, antimalarials, antitubercular drugs, antihypertensives, psychiatric drugs, chemotherapeutic agents, diuretic, heavy metals, NSAIDs, etc. Terbinafine, an antifungal agent, is widely used for dermatophyte infections and onychomyc...

journal_title：Cutaneous and ocular toxicology

authors： Zheng Y,Zhang J,Chen H,Lai W,Maibach HI

更新日期：2017-03-01 00:00:00

abstract：PURPOSE:The aim of this study was to examine the effects of long-term use of hydroxychloroquine (HQ) on the pachymetric, aberrometric, and densitometric values of the cornea and corneal endothelium in lupus patients. METHOD:Twenty-two eyes (study group) of 22 patients using HQ for treatment of lupus and 25 eyes (contr...

journal_title：Cutaneous and ocular toxicology

authors： Çağlayan M,Akyol L,Balcı MA,Öncül H,Alakuş MF,Dağ U

更新日期：2020-12-23 00:00:00

abstract：:Rapid decontamination is vital to alleviate adverse health effects following dermal exposure to hazardous materials. There is an abundance of materials and products which can be utilised to remove hazardous materials from the skin. In this study, a total of 15 products were evaluated, 10 of which were commercial or mi...

journal_title：Cutaneous and ocular toxicology

authors： Matar H,Guerreiro A,Piletsky SA,Price SC,Chilcott RP

更新日期：2016-01-01 00:00:00

abstract：:Ciliary body is responsible for humour aqueous production in posterior chamber. Valproic acid (VPA) has been widely used for the treatment of epilepsy and other neuropsychiatric diseases such as bipolar disease and major depression. Oxcarbazepine (OXC) is a new anti-epileptic agent that has been used recently for chil...

journal_title：Cutaneous and ocular toxicology

authors： Göktaş G,Aktaş Z,Erdoğan D,Seymen CM,Karaca EE,Cansu A,Serdaroğlu A,Kaplanoğlu GT

更新日期：2015-01-01 00:00:00

abstract：:Psoriasis is a common skin disorder that needs a long-term management, not only because, of its prevalence but also because of the profound impact it can have on patients quality of life. Drugs may result in exacerbation of a preexisting psoriasis, in induction of psoriatic lesions on clinically uninvolved skin in pat...

journal_title：Cutaneous and ocular toxicology

authors： Dika E,Varotti C,Bardazzi F,Maibach HI

更新日期：2006-01-01 00:00:00

abstract：PURPOSE:To evaluate the effects of the topical application of nondiluted autologous serum on epithelial healing as an adjuvant therapy in rabbit corneal alkali wounds. METHODS:Central corneal alkali wounds were produced on the right eye of 16 rabbits, by a 60-second application of a 6-mm round filter paper soaked in 1...

journal_title：Cutaneous and ocular toxicology

authors： Salman IA,Gündoğdu C

更新日期：2010-06-01 00:00:00

abstract：:The terrifying dog in the Hound of the Baskervilles is described as having 'blazing eyes' and a 'luminous muzzle', appearances attributed by Watson and Holmes to the application of phosphorus. Review of the toxicity and flammability of white phosphorus make this improbable. It is suggested that Conan Doyle's descripti...

journal_title：Cutaneous and ocular toxicology

authors： Dayan AD

更新日期：2008-01-01 00:00:00

abstract：PURPOSE:To assess the long-term intraocular pressure (IOP) changes after the intravitreal injection of bevacizumab (Avastin; Genentech, Inc., South San Francisco, CA) for treatment of age-related macular degeneration (AMD) and diabetic macular edema (DME) patients and evaluate the correlation factors. MATERIAL AND MET...

journal_title：Cutaneous and ocular toxicology

authors： Baek SU,Park IW,Suh W

更新日期：2016-12-01 00:00:00

abstract：CONTEXT:Nicorandil is an antianginal drug used for 20 years in Japan and introduced in France in 1994. Since 1997, side effects such as mucocutaneous ulcerations have regularly been reported. OBJECTIVE:To describe the first case of a patient with a spontaneous corneal perforation associated with mucocutaneous ulcerati...

journal_title：Cutaneous and ocular toxicology

authors： Campolmi N,Guy C,Cinotti E,Forest F,Gain P,Philippe-Zech C,Gauthier AS,Thuret G

更新日期：2014-06-01 00:00:00

abstract：:The most common adverse effects of oral isotretinoin (>1/10) are: cheilitis, skin dryness, erythema, itching, scaling, bruising, skin atopy, conjunctivitis, dry eyes and eyelid inflammation. The aim of this work was to define an optimal dose regime of the oral isotretinoin allowing for effective reduction of sebum pro...

journal_title：Cutaneous and ocular toxicology

authors： Bergler-Czop B,Brzezińska-Wcisło L

更新日期：2012-09-01 00:00:00

abstract：OBJECTIVE:This report, the second in a series of five, directly compares the efficacy of Reactive Skin Decontamination Lotion (RSDL), the M291 Skin Decontamination Kit (SDK), 0.5% bleach (sodium or calcium hypochlorite solution), 1% soapy water, and Skin Exposure Reduction Paste Against Chemical Warfare Agents (SERPACW...

journal_title：Cutaneous and ocular toxicology

authors： Braue EH Jr,Smith KH,Doxzon BF,Lumpkin HL,Clarkson ED

更新日期：2011-03-01 00:00:00

abstract：PURPOSE:To find the abnormalities in various retinal layers caused by radiation retinopathy using spectral domain optical coherence tomography (SD-OCT). METHODS:We report a case of radiation retinopathy that was imaged using SD-OCT Copernicus (Optopol, Zawiercie, Poland). Analysis and synthesis of the OCT image were d...

journal_title：Cutaneous and ocular toxicology

authors： Raman R,Pal SS,Krishnan T,Laxmi G,Radke N,Sharma T

更新日期：2010-03-01 00:00:00

abstract：PURPOSE:To evaluate the treatment of autologous serum eye drops (ASED) on dry eyes in patients with graft-versus-host disease (GVHD). METHODS:A retrospective chart review of 35 patients with a history of ocular GVHD following hematopoietic stem cell transplantation that used ASED to alleviate dry eye symptoms was perf...

journal_title：Cutaneous and ocular toxicology

authors： Azari AA,Karadag R,Kanavi MR,Nehls S,Barney N,Kim K,Longo W,Hematti P,Juckett M

更新日期：2017-06-01 00:00:00

abstract：:We report a case of ophthalmic antibiotic ointment in the anterior chamber following uneventful phacoemulsification surgery. Antibiotic ointment was observed in the superior angle beneath the clear corneal wound one month later. The patient remained asymptomatic for 26 months after surgery until mild iritis developed....

journal_title：Cutaneous and ocular toxicology

authors： Ugurbas SC,Akova YA

更新日期：2010-09-01 00:00:00

abstract：OBJECTIVE:To describe 8 cases of toxic keratopathy due to abuse of topical anesthetic drugs. METHODS:Clinical findings from patients with toxic keratopathy were investigated retrospectively. RESULTS:Two patients had toxic keratopathy bilaterally. Five of 8 patients had an ocular history of a corneal foreign body, 1 h...

journal_title：Cutaneous and ocular toxicology

authors： Yeniad B,Canturk S,Esin Ozdemir F,Alparslan N,Akarcay K

更新日期：2010-06-01 00:00:00

abstract：:Chemical sensitization is a serious condition caused by small reactive molecules and is characterized by a delayed type hypersensitivity known as allergic contact dermatitis (ACD). Contact with these molecules via dermal exposure represent a significant concern for chemical manufacturers. Recent legislation in the EU ...

journal_title：Cutaneous and ocular toxicology

authors： McKim JM Jr,Keller DJ 3rd,Gorski JR

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:There is increasing interest in minimally invasive skin sampling techniques to assay markers of molecular biology and biochemical processes. OBJECTIVE:This overview examines methodology strengths and limitations, and exciting developments pending in the scientific community. MATERIALS AND METHODS:Publicati...

journal_title：Cutaneous and ocular toxicology

authors： Wang CY,Maibach HI

更新日期：2011-03-01 00:00:00

abstract：:Basal cell carcinoma (BCC), the most frequent malignant skin tumor observed in Caucasian adults, especially males, occurs mainly in sun-exposed areas of the body. BCC in the periungual tissues, such as proximal nail fold, nail matrix, nail bed and hyponychium, is rarely reported. We report a patient with two synchrono...

journal_title：Cutaneous and ocular toxicology

authors： Dika E,Patrizi A,Fanti PA,Alessandrini A,Sorci R,Piraccini BM,Vaccari S,Misciali C,Maibach HI

更新日期：2013-06-01 00:00:00

abstract：:Pustular irritant contact dermatitis is rare and unusual clinic form of contact dermatitis. Dexpanthenol is the stable alcoholic analogue of pantothenic acid. It is widely used in cosmetics and topical medical products for several purposes. We present the case of 8-year-old girl with pustules over erythematous and ecz...

journal_title：Cutaneous and ocular toxicology

authors： Gulec AI,Albayrak H,Uslu E,Başkan E,Aliagaoglu C

更新日期：2015-03-01 00:00:00

abstract：:A brief comment on efficacy and safety of propranolol in the treatment of parotid hemangioma is presented, with illustration of a typical case. ...

journal_title：Cutaneous and ocular toxicology

authors： Zheng JW

更新日期：2011-12-01 00:00:00

abstract：CONTEXT:Assessing the hazards of accidental exposure to toxic industrial chemical (TIC) vapors and evaluating therapeutic compounds or treatment regimens require the development of appropriate animal models. OBJECTIVE:The objective of this project was to develop an exposure system for delivering controlled vapor conce...

journal_title：Cutaneous and ocular toxicology

authors： Snider TH,Perry MR,Richter WR,Plahovinsak JL,Rogers J,Reid FM,Graham JS

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:Fixed drug eruption (FDE) is a special variant of drug reaction seen on skin or mucous membrane, and typically recurs at the same location. Ornidazole-induced FDE cases have been reported extremely rare. CASE:The 48-year-old female patient was diagnosed for ornidazole-induced fixed drug reaction on the sole...

journal_title：Cutaneous and ocular toxicology

authors： Emre S,Ahsen H,Aktaş A

更新日期：2017-09-01 00:00:00

abstract：PURPOSE:Hazelnut and birch pollen are known to destroy tear film components and attack ocular surface cells. We investigated further pollen species from different plant families, whether they show similar effects on human tear fluid and an epithelial cell line in vitro, to provide a broad basis for further research on ...

journal_title：Cutaneous and ocular toxicology

authors： Rabensteiner DF,Rabensteiner J,Horwath-Winter J,Lang-Loidolt D,Wedrich A,Heidinger A,Schwantzer G,Schmut O

更新日期：2019-03-01 00:00:00

abstract：:Fixed drug eruption (FDE) is a rare form of drug allergies that recur at the same cutaneous or mucosal site in every usage of drug. Single or multiple round, sharply demarcated and dusky red plaques appear soon after drug exposure. Ursodeoxycholic acid (UDCA: 3α,7β-dihydroxy-5β-cholanic acid) is used for the treatment...

journal_title：Cutaneous and ocular toxicology

authors： Ozkol HU,Calka O,Dulger AC,Bulut G

更新日期：2014-09-01 00:00:00

abstract：CONTEXT:The acute effects of cigarette smoking on pupil size and ocular wavefront aberrations (OWA) have been previously documented. The accommodation status of the eye is well known to be related to ocular aberrations. No previous study has evaluated the impact of cigarette smoking on the accommodation status of the e...

journal_title：Cutaneous and ocular toxicology

authors： Bardak H,Gunay M,Bardak Y,Ercalik Y,Imamoglu S,Yildiz E,Gunay BO

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:The exact immunopathogenesis of contact hypersensitivity (CH) to mercury remains unclear. OBJECTIVE:The aim of the present study was to assess the role of CD4+ T cells in mercury-induced CH in mice. METHODS:Splenic CD4+ T cells obtained from nonsensitized and mercury-sensitized Balb/c mice were adoptively ...

journal_title：Cutaneous and ocular toxicology

authors： Sumiwi YA,Soesatyo MH,Sosroseno W

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:Paederus dermatitis (PD), which is an irritant contact dermatitis, is common throughout the world and caused by rove beetles. OBJECTIVES:To assess the clinical features of PD and the level of knowledge of patients from the city of Batman and surrounding areas who presented with the condition. METHODS:We de...

journal_title：Cutaneous and ocular toxicology

authors： Turan E

更新日期：2014-09-01 00:00:00

abstract：PURPOSE:Evaluation of retinal and choroidal changes after energy drink consumption by optical coherence tomography and optical coherence tomography angiography. METHODS AND MATERIAL:Forty-two healthy volunteers with neither systemic nor ocular diseases were enrolled in the study. The energy drink (250 mL Red Bull ener...

journal_title：Cutaneous and ocular toxicology

authors： Doğan M,Sabaner MC,Akar AT,Şenel M,Kaşikçi İ,Günal EŞ,Özbay AE,Şarman T,Gobeka HH,Cam Ö

更新日期：2020-12-01 00:00:00