The role of CD4+ T cells in the induction of contact hypersensitivity to mercury in a murine model.

abstract：CONTEXT:Nicorandil is an antianginal drug used for 20 years in Japan and introduced in France in 1994. Since 1997, side effects such as mucocutaneous ulcerations have regularly been reported. OBJECTIVE:To describe the first case of a patient with a spontaneous corneal perforation associated with mucocutaneous ulcerati...

journal_title：Cutaneous and ocular toxicology

authors： Campolmi N,Guy C,Cinotti E,Forest F,Gain P,Philippe-Zech C,Gauthier AS,Thuret G

更新日期：2014-06-01 00:00:00

abstract：:We report a 9-month-old male patient with autoimmune enteropathy treated with intravenous methylprednisolone who developed firm, red, subcutaneous nodules 20 days after abrupt steroid interruption. The diagnosis of poststeroid panniculitis (PSP) was made based on clinical and histological grounds. PSP is an unusual co...

journal_title：Cutaneous and ocular toxicology

authors： Peralta L,Morais P,Trindade E,Barreto F,Canelhas Á,Amil J

更新日期：2012-06-01 00:00:00

abstract：PURPOSE:Warfarin (WF) is an anticoagulant which also affects physiological processes other than hemostasis. Our previous investigations showed the effect of WF which gained access to the organism via skin on resting peripheral blood granulocytes. Based on these data, the aim of the present study was to examine whether ...

journal_title：Cutaneous and ocular toxicology

authors： Mirkov I,Popov Aleksandrov A,Demenesku J,Ninkov M,Mileusnic D,Kataranovski D,Kataranovski M

更新日期：2017-09-01 00:00:00

abstract：PURPOSE:To investigate the corneal toxicity of Xalatan and three latanoprost generics using transepithelial electrical resistance (TER) and scanning electron microscopy (SEM). METHODS:Corneal TER changes after a 60-s exposure to Xalatan (latanoprost 0.005% preserved with 0.02% BAC), and latanoprost generics (Latanopro...

journal_title：Cutaneous and ocular toxicology

authors： Uematsu M,Mohamed YH,Onizuka N,Ueki R,Inoue D,Fujikawa A,Sasaki H,Kitaoka T

更新日期：2016-01-01 00:00:00

abstract：:The skin undergoes a lifetime of degenerative changes with the potential for genetic mutations occurring from exposure to solar radiation. Benign neoplasms afflict virtually every individual over the age of 65, and more often than not afflicted individuals carry large numbers of growths. Malignant neoplasms, which can...

journal_title：Cutaneous and ocular toxicology

authors： Farage MA,Miller KW,Berardesca E,Maibach HI

更新日期：2008-01-01 00:00:00

abstract：PURPOSES:To study the occurrence of ocular surface diseases on coal miners working under wells and to investigate the relation between xerophthalmia occurrence and coal dust contiguity. METHODS:To observe the influence of coal dust to ocular surface by using Schirmer to detect lacrimal gland secreting function, and br...

journal_title：Cutaneous and ocular toxicology

authors： Sun Z,Hong J,Yang D,Liu G

更新日期：2007-01-01 00:00:00

abstract：PURPOSE:The aim of this study was to examine the effects of long-term use of hydroxychloroquine (HQ) on the pachymetric, aberrometric, and densitometric values of the cornea and corneal endothelium in lupus patients. METHOD:Twenty-two eyes (study group) of 22 patients using HQ for treatment of lupus and 25 eyes (contr...

journal_title：Cutaneous and ocular toxicology

authors： Çağlayan M,Akyol L,Balcı MA,Öncül H,Alakuş MF,Dağ U

更新日期：2020-12-23 00:00:00

abstract：BACKGROUND:There is increasing interest in minimally invasive skin sampling techniques to assay markers of molecular biology and biochemical processes. OBJECTIVE:This overview examines methodology strengths and limitations, and exciting developments pending in the scientific community. MATERIALS AND METHODS:Publicati...

journal_title：Cutaneous and ocular toxicology

authors： Wang CY,Maibach HI

更新日期：2011-03-01 00:00:00

abstract：:In this report we present a case of erlotinib-induced trichomegaly in a male patient who received erlotinib for his pancreatic cancer. Trichomegaly as a side effect of epidermal growth factor receptor (EGFR) inhibitor therapy is uncommon in male patients. Also, it has not been reported previously in a patient with pan...

journal_title：Cutaneous and ocular toxicology

authors： Saif MW,Gnanaraj J

更新日期：2010-03-01 00:00:00

abstract：PURPOSE:Welding workers' ophthalmic problems resulting from their professions are frequently observed in ophthalmic emergencies and can cause severe visual impairment. We aimed to investigate the use of topical anesthetic and non-medical alternatives of this population regarding ophthalmic problems in this study. MATE...

journal_title：Cutaneous and ocular toxicology

authors： Aslan L,Sucakli MH,Bozkurt S,Aslankurt M,Aksoy A,Celik M

更新日期：2014-06-01 00:00:00

abstract：CONTEXT:Assessing the hazards of accidental exposure to toxic industrial chemical (TIC) vapors and evaluating therapeutic compounds or treatment regimens require the development of appropriate animal models. OBJECTIVE:The objective of this project was to develop an exposure system for delivering controlled vapor conce...

journal_title：Cutaneous and ocular toxicology

authors： Snider TH,Perry MR,Richter WR,Plahovinsak JL,Rogers J,Reid FM,Graham JS

更新日期：2014-06-01 00:00:00

abstract：PURPOSE:To evaluate the short- and long-term effects of selective serotonin reuptake inhibitors (SSRIs) on intraocular pressure (IOP) and anterior segment parameters in open angle eyes. MATERIALS AND METHODS:This cross-sectional study included 325 eyes of 166 subjects. Subjects were divided into three groups: Group 1 ...

journal_title：Cutaneous and ocular toxicology

authors： Gündüz GU,Parmak Yener N,Kılınçel O,Gündüz C

更新日期：2018-03-01 00:00:00

abstract：PURPOSE:Hazelnut and birch pollen are known to destroy tear film components and attack ocular surface cells. We investigated further pollen species from different plant families, whether they show similar effects on human tear fluid and an epithelial cell line in vitro, to provide a broad basis for further research on ...

journal_title：Cutaneous and ocular toxicology

authors： Rabensteiner DF,Rabensteiner J,Horwath-Winter J,Lang-Loidolt D,Wedrich A,Heidinger A,Schwantzer G,Schmut O

更新日期：2019-03-01 00:00:00

abstract：OBJECTIVE:To investigate the effects of topiramate on choroidal thickness and anterior chamber parameters using optical coherence tomography in the treatment of patients with migraine. METHODS:A total of 22 eyes of 22 adults (12 females, 10 males) diagnosed with migraine and scheduled to topiramate treatment for pain ...

journal_title：Cutaneous and ocular toxicology

authors： Gok M,Ozdemir O

更新日期：2017-12-01 00:00:00

abstract：:Patch testing is an important tool in the diagnosis of allergic contact dermatitis. Although this technique can be accurate, occasionally the results may be inconclusive. A previously positive result to an allergen may become negative upon repeat testing, and this may complicate the process of achieving a definitive d...

journal_title：Cutaneous and ocular toxicology

authors： Zapolanski T,Maibach HI

更新日期：2008-01-01 00:00:00

abstract：:Attempts to improve formulation of topical products are a continuing process and the development of micro- and nanovesicular systems as well as polymeric microparticles has led to marketing of topical drugs and cosmetics using these technologies. Encapsulation of some well-known contact allergens in ethanolic liposome...

journal_title：Cutaneous and ocular toxicology

authors： Madsen JT,Vogel S,Johansen JD,Andersen KE

更新日期：2011-06-01 00:00:00

abstract：PURPOSE:Following methanol intoxication, optic nerve neuropathy may occur, which is currently treated by different therapeutic regimens. Erythropoietin (EPO) has recently been introduced as a good therapeutic option in methanol-induced optic neuropathy. The aim of the current study was to evaluate the efficacy of EPO i...

journal_title：Cutaneous and ocular toxicology

authors： Zamani N,Hassanian-Moghaddam H,Shojaei M,Rahimian S

更新日期：2018-06-01 00:00:00

abstract：:Drug-induced lichen planus has been induced by antibiotics, anticonvulsants, antidiabetics, antimalarials, antitubercular drugs, antihypertensives, psychiatric drugs, chemotherapeutic agents, diuretic, heavy metals, NSAIDs, etc. Terbinafine, an antifungal agent, is widely used for dermatophyte infections and onychomyc...

journal_title：Cutaneous and ocular toxicology

authors： Zheng Y,Zhang J,Chen H,Lai W,Maibach HI

更新日期：2017-03-01 00:00:00

abstract：OBJECTIVE:To describe 8 cases of toxic keratopathy due to abuse of topical anesthetic drugs. METHODS:Clinical findings from patients with toxic keratopathy were investigated retrospectively. RESULTS:Two patients had toxic keratopathy bilaterally. Five of 8 patients had an ocular history of a corneal foreign body, 1 h...

journal_title：Cutaneous and ocular toxicology

authors： Yeniad B,Canturk S,Esin Ozdemir F,Alparslan N,Akarcay K

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:The massive uptake of compatible osmolytes is a self-protective response shared by retina exposed to hypertonic stress and ultraviolet stress. OBJECTIVE:This study aimed to investigate the protective effects of taurine against ultraviolet damage in human retinal pigment epithelium cells. METHODS:Real-time ...

journal_title：Cutaneous and ocular toxicology

authors： Dayang W,Jinsong Z

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:In our study, we aimed to show the effects of smoking on choroidal thickness and ocular pulse amplitude. It is known that the anatomy and physiologic functions of the choroid is important in ocular diseases like glaucoma and age-related macular degeneration. Choroidal thickness is measured by the spectral do...

journal_title：Cutaneous and ocular toxicology

authors： Dervişoğulları MS,Totan Y,Tenlik A,Yuce A

更新日期：2015-01-01 00:00:00

abstract：:There is a concern that peptides in cosmetic creams marketed as anti-aging/anti-wrinkle may penetrate into the deep layers of the skin and potentially stimulate biological activity. Claims for one cosmetic peptide, acetyl hexapeptide-8 (Ac-EEMQRR-amide), suggest interference with neuromuscular signaling as its anti-wr...

journal_title：Cutaneous and ocular toxicology

authors： Kraeling ME,Zhou W,Wang P,Ogunsola OA

更新日期：2015-03-01 00:00:00

abstract：:Pustular irritant contact dermatitis is rare and unusual clinic form of contact dermatitis. Dexpanthenol is the stable alcoholic analogue of pantothenic acid. It is widely used in cosmetics and topical medical products for several purposes. We present the case of 8-year-old girl with pustules over erythematous and ecz...

journal_title：Cutaneous and ocular toxicology

authors： Gulec AI,Albayrak H,Uslu E,Başkan E,Aliagaoglu C

更新日期：2015-03-01 00:00:00

abstract：:Background: Papulopustular rash is the most common cutaneous adverse effect during targeted tumour therapy particularly with epidermal growth factor receptor inhibitors (EGFRIs). Objective: To evaluate the adverse skin reactions, mainly papulopustular rash, caused by targeted tumour therapy. Materials and methods: We ...

journal_title：Cutaneous and ocular toxicology

authors： Yalici-Armagan B,Ayanoglu BT,Demirdag HG

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Systemic isotretinoin (13-cis-retinoic acid) is effective in the treatment of acne vulgaris. The most common side effects are mucocutaneous ones. Hematuria seen secondary to isotretinoin treatment is thought to be due to mucosal dryness in the urinary system. This study aims to determine the frequency of hem...

journal_title：Cutaneous and ocular toxicology

authors： Yesilkaya B,Alli N,Artuz RF,Ulu E,Kartal D,Cinar SL

更新日期：2017-03-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to investigate the antioxidant and radioprotective effects of Nigella sativa oil (NSO) and thymoquinone (TQ) against ionizing radiation-induced cataracts in lens after total cranium irradiation (IR) of rats with a single dose of 5 gray (Gy). MATERIALS AND METHODS:Seventy-four Spragu...

journal_title：Cutaneous and ocular toxicology

authors： Taysi S,Abdulrahman ZK,Okumus S,Demir E,Demir T,Akan M,Saricicek E,Saricicek V,Aksoy A,Tarakcioglu M

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:This report, the second in a series of five, directly compares the efficacy of Reactive Skin Decontamination Lotion (RSDL), the M291 Skin Decontamination Kit (SDK), 0.5% bleach (sodium or calcium hypochlorite solution), 1% soapy water, and Skin Exposure Reduction Paste Against Chemical Warfare Agents (SERPACW...

journal_title：Cutaneous and ocular toxicology

authors： Braue EH Jr,Smith KH,Doxzon BF,Lumpkin HL,Clarkson ED

更新日期：2011-03-01 00:00:00

abstract：:The most common side effects of interferon-beta therapy following subcutaneous administration include pain, inflammation and induration at the injection site, which occur in approximately 20-60% of patients. Besides, transient injection-site erythema is frequently seen in beta-interferon therapy. Less frequent reactio...

journal_title：Cutaneous and ocular toxicology

authors： Ozuguz P,Kacar SD,Karaca S,Tokyol C

更新日期：2014-12-01 00:00:00

abstract：:Purpose: We have previously reported that skin barrier function is disrupted in mice with colonic tumours induced by azoxymethane (AOM) and dextran sodium sulphate (DSS). We postulated that the impaired skin barrier function was associated with reactive oxygen species derived from gp91phox. In this study, we investiga...

journal_title：Cutaneous and ocular toxicology

authors： Yokoyama S,Hiramoto K,Yamate Y

更新日期：2019-12-01 00:00:00

abstract：OBJECTIVE:To assess the incidence of seizures induced by cycloplegic ophthalmic drops. MATERIALS AND METHODS:A survey among members of the American Association for Pediatric Ophthalmology and Strabismus yielded five patients who received cycloplegic eye drops between 1998 and 2010 and who consequently developed a seiz...

journal_title：Cutaneous and ocular toxicology

authors： Wygnanski-Jaffe T,Nucci P,Goldchmit M,Mezer E

更新日期：2014-06-01 00:00:00