Abstract:
OBJECTIVE:To describe 8 cases of toxic keratopathy due to abuse of topical anesthetic drugs. METHODS:Clinical findings from patients with toxic keratopathy were investigated retrospectively. RESULTS:Two patients had toxic keratopathy bilaterally. Five of 8 patients had an ocular history of a corneal foreign body, 1 had basal membrane dystrophy, 1 had ultraviolet radiation, and 1 had chemical burn. All patients had undergone psychiatric consultation. Four patients had anxiety disorder and 1 had bipolar disease. Clinical signs were improved in all patients with discontinuation of topical anesthetic drug use along with adjunctive psychiatric treatment. Penetrating keratoplasty was performed in 2 patients. CONCLUSION:Toxic keratopathy due to topical anesthetic abuse is a curable disease. Early diagnosis and prevention of topical anesthetic drug use are the most important steps in the treatment of this condition. As these patients commonly exhibit psychiatric disorders, adjunctive psychiatric treatment may help to break the chemical addiction.
journal_name
Cutan Ocul Toxicoljournal_title
Cutaneous and ocular toxicologyauthors
Yeniad B,Canturk S,Esin Ozdemir F,Alparslan N,Akarcay Kdoi
10.3109/15569521003631752subject
Has Abstractpub_date
2010-06-01 00:00:00pages
105-9issue
2eissn
1556-9527issn
1556-9535journal_volume
29pub_type
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