Ursodeoxycholic acid induced generalized fixed drug eruption.

Abstract:

:Fixed drug eruption (FDE) is a rare form of drug allergies that recur at the same cutaneous or mucosal site in every usage of drug. Single or multiple round, sharply demarcated and dusky red plaques appear soon after drug exposure. Ursodeoxycholic acid (UDCA: 3α,7β-dihydroxy-5β-cholanic acid) is used for the treatment of cholestatic liver diseases. Some side effects may be observed, such as diarrhea, dyspepsia, pruritus and headaches. We encountered only three cases of lichenoid reaction regarding the use of UDCA among previous studies. In this article, we reported a generalized FDE case related to UDCA intake in a 59-year-old male patient with cholestasis for the first time in the literature.

journal_name

Cutan Ocul Toxicol

authors

Ozkol HU,Calka O,Dulger AC,Bulut G

doi

10.3109/15569527.2013.838253

subject

Has Abstract

pub_date

2014-09-01 00:00:00

pages

256-8

issue

3

eissn

1556-9527

issn

1556-9535

journal_volume

33

pub_type

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