The new therapy schema of the various kinds of acne based on the mucosa-skin side effects of the retinoids.

abstract：:Erlotinib is a tyrosine kinase inhibitor of the epidermal growth factor receptor. Since there is a wide expression of the epidermal growth factor receptors in the epithelial tissues of ocular surface and adnexa, ocular adverse reactions may happen during systemic administration of erlotinib. Previously reported ocular...

journal_title：Cutaneous and ocular toxicology

authors： Kau HC,Tsai CC

更新日期：2016-09-01 00:00:00

abstract：:Basal cell carcinoma (BCC), the most frequent malignant skin tumor observed in Caucasian adults, especially males, occurs mainly in sun-exposed areas of the body. BCC in the periungual tissues, such as proximal nail fold, nail matrix, nail bed and hyponychium, is rarely reported. We report a patient with two synchrono...

journal_title：Cutaneous and ocular toxicology

authors： Dika E,Patrizi A,Fanti PA,Alessandrini A,Sorci R,Piraccini BM,Vaccari S,Misciali C,Maibach HI

更新日期：2013-06-01 00:00:00

abstract：:Erythema multiforme (EM) is an immune-mediated mucocutaneous eruption characterized by symmetrically distributed, polymorphic targetoid lesions, mostly on the distal parts of the extremities. It occurs mostly in the setting of an infection in certain predisposed individuals. A 30-year-old pregnant woman was presented ...

journal_title：Cutaneous and ocular toxicology

authors： Özyurt S,Er O,Afsar FS,Ermete M

更新日期：2013-09-01 00:00:00

abstract：PURPOSE:The aim of this study was to examine the effects of long-term use of hydroxychloroquine (HQ) on the pachymetric, aberrometric, and densitometric values of the cornea and corneal endothelium in lupus patients. METHOD:Twenty-two eyes (study group) of 22 patients using HQ for treatment of lupus and 25 eyes (contr...

journal_title：Cutaneous and ocular toxicology

authors： Çağlayan M,Akyol L,Balcı MA,Öncül H,Alakuş MF,Dağ U

更新日期：2020-12-23 00:00:00

abstract：PURPOSE:Hazelnut and birch pollen are known to destroy tear film components and attack ocular surface cells. We investigated further pollen species from different plant families, whether they show similar effects on human tear fluid and an epithelial cell line in vitro, to provide a broad basis for further research on ...

journal_title：Cutaneous and ocular toxicology

authors： Rabensteiner DF,Rabensteiner J,Horwath-Winter J,Lang-Loidolt D,Wedrich A,Heidinger A,Schwantzer G,Schmut O

更新日期：2019-03-01 00:00:00

abstract：:The skin undergoes a lifetime of degenerative changes with the potential for genetic mutations occurring from exposure to solar radiation. Benign neoplasms afflict virtually every individual over the age of 65, and more often than not afflicted individuals carry large numbers of growths. Malignant neoplasms, which can...

journal_title：Cutaneous and ocular toxicology

authors： Farage MA,Miller KW,Berardesca E,Maibach HI

更新日期：2008-01-01 00:00:00

abstract：:Purpose: We have previously reported that skin barrier function is disrupted in mice with colonic tumours induced by azoxymethane (AOM) and dextran sodium sulphate (DSS). We postulated that the impaired skin barrier function was associated with reactive oxygen species derived from gp91phox. In this study, we investiga...

journal_title：Cutaneous and ocular toxicology

authors： Yokoyama S,Hiramoto K,Yamate Y

更新日期：2019-12-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to investigate the antioxidant and radioprotective effects of Nigella sativa oil (NSO) and thymoquinone (TQ) against ionizing radiation-induced cataracts in lens after total cranium irradiation (IR) of rats with a single dose of 5 gray (Gy). MATERIALS AND METHODS:Seventy-four Spragu...

journal_title：Cutaneous and ocular toxicology

authors： Taysi S,Abdulrahman ZK,Okumus S,Demir E,Demir T,Akan M,Saricicek E,Saricicek V,Aksoy A,Tarakcioglu M

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:The aim of this study is to compare the effect of prostaglandin analogues preserved with either 0.015% or 0.001% benzalkoium chloride (BAK); or 0.001% polyquad (PQ) on the ocular surface of rabbit eyes. METHODS:Forty white rabbits were randomized to receive four-times daily instillation of either 0.0015% taf...

journal_title：Cutaneous and ocular toxicology

authors： Lee HJ,Jun RM,Cho MS,Choi KR

更新日期：2015-01-01 00:00:00

abstract：PURPOSE:To evaluate antioxidant effects of active vitamin D (calcitriol) against high-dose radioiodine (RAI) therapy-associated damage of lacrimal gland. MATERIALS AND METHODS:Wistar albino rats were used and divided into three groups randomly (n = 12/group). The first group was appointed as the negative control group...

journal_title：Cutaneous and ocular toxicology

authors： Eksioglu U,Atilgan HI,Yakin M,Yazihan N,Altiparmak UE,Yumusak N,Korkmaz M,Demir A,Ornek F,Aribal Ayral P,Koca G

更新日期：2019-03-01 00:00:00

abstract：PURPOSE:To evaluate the treatment of autologous serum eye drops (ASED) on dry eyes in patients with graft-versus-host disease (GVHD). METHODS:A retrospective chart review of 35 patients with a history of ocular GVHD following hematopoietic stem cell transplantation that used ASED to alleviate dry eye symptoms was perf...

journal_title：Cutaneous and ocular toxicology

authors： Azari AA,Karadag R,Kanavi MR,Nehls S,Barney N,Kim K,Longo W,Hematti P,Juckett M

更新日期：2017-06-01 00:00:00

abstract：PURPOSE:Welding workers' ophthalmic problems resulting from their professions are frequently observed in ophthalmic emergencies and can cause severe visual impairment. We aimed to investigate the use of topical anesthetic and non-medical alternatives of this population regarding ophthalmic problems in this study. MATE...

journal_title：Cutaneous and ocular toxicology

authors： Aslan L,Sucakli MH,Bozkurt S,Aslankurt M,Aksoy A,Celik M

更新日期：2014-06-01 00:00:00

abstract：PURPOSE:To evaluate the effect of anti-tubercular treatment on retinal nerve fiber layer (RNFL) thickness and the efficiency of optic coherence tomography (OCT) on early diagnosis of optic neuropathy. METHODS:Twenty patients diagnosed with either pulmonary or extra-pulmonary tuberculosis which were treated with anti-t...

journal_title：Cutaneous and ocular toxicology

authors： Gümüş A,Öner V

更新日期：2015-01-01 00:00:00

abstract：PURPOSE:To evaluate the efficacy of heparin eye drops in the treatment of paraquat-induced ocular surface injury. DESIGN AND METHODS:In this retrospective study, we included 25 patients (31 eyes) with paraquat-induced ocular surface injury, who attended the Affiliated Hospital of Weifang Medical University between Oct...

journal_title：Cutaneous and ocular toxicology

authors： Jian-Wei L,Xiu-Yun L,Ai-Jun D

更新日期：2017-12-01 00:00:00

abstract：CONTEXT:Nicorandil is an antianginal drug used for 20 years in Japan and introduced in France in 1994. Since 1997, side effects such as mucocutaneous ulcerations have regularly been reported. OBJECTIVE:To describe the first case of a patient with a spontaneous corneal perforation associated with mucocutaneous ulcerati...

journal_title：Cutaneous and ocular toxicology

authors： Campolmi N,Guy C,Cinotti E,Forest F,Gain P,Philippe-Zech C,Gauthier AS,Thuret G

更新日期：2014-06-01 00:00:00

abstract：:Dermal absorption of some chemicals and drugs can cause systemic toxicity. We evaluated several case reports from the past decade, which discuss the dermal absorption of a specific chemical and potential local and systemic effects. We focused on herbicide and pesticide exposure along with exposure to cutaneous medicat...

journal_title：Cutaneous and ocular toxicology

authors： Alikhan FS,Maibach H

更新日期：2011-09-01 00:00:00

abstract：:The assessment of the potency of a skin sensitizing chemical is a key starting point for its subsequent risk assessment/management. The Local Lymph Node Assay can provide information on the relative skin sensitizing potency of contact allergens by interpolation from the dose response curve the concentration of a chemi...

journal_title：Cutaneous and ocular toxicology

authors： Ryan CA,Chaney JG,Gerberick GF,Kern PS,Dearman RJ,Kimber I,Basketter DA

更新日期：2007-01-01 00:00:00

abstract：:We report a case of iris atrophy and corneal endothelial decompensation following the inadvertent use of water-based ink for capsular staining during cataract surgery. The anterior chamber was thoroughly irrigated with balanced salt solution after the identification of the wrong dye. Phacoemulsification with minimal u...

journal_title：Cutaneous and ocular toxicology

authors： Kugu S,Erdogan G,Kandemir B,Dogan OK

更新日期：2009-01-01 00:00:00

abstract：:In the EU, Methylisothiazolinone (MI) was approved as a preservative in cosmetics and household products in 2005. Since then, several cases of MI contact allergy have been reported. We studied the prevalence of MI sensitization in patients allergic to Methylchloroisothiazolinone/Methylisothiazolinone (MCI/MI). From a ...

journal_title：Cutaneous and ocular toxicology

authors： Macias VC,Fernandes S,Amaro C,Santos R,Cardoso J

更新日期：2013-06-01 00:00:00

abstract：:The skin is a major exposure route for many potentially toxic chemicals. It is, therefore, important to be able to predict the permeability of compounds through skin under a variety of conditions. Available skin permeability databases are often limited in scope and not conducive to developing effective models. This sp...

journal_title：Cutaneous and ocular toxicology

authors： Keshwani DR,Jones DD,Brand RM

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:The exact immunopathogenesis of contact hypersensitivity (CH) to mercury remains unclear. OBJECTIVE:The aim of the present study was to assess the role of CD4+ T cells in mercury-induced CH in mice. METHODS:Splenic CD4+ T cells obtained from nonsensitized and mercury-sensitized Balb/c mice were adoptively ...

journal_title：Cutaneous and ocular toxicology

authors： Sumiwi YA,Soesatyo MH,Sosroseno W

更新日期：2010-03-01 00:00:00

abstract：PURPOSE:To evaluate the short- and long-term effects of selective serotonin reuptake inhibitors (SSRIs) on intraocular pressure (IOP) and anterior segment parameters in open angle eyes. MATERIALS AND METHODS:This cross-sectional study included 325 eyes of 166 subjects. Subjects were divided into three groups: Group 1 ...

journal_title：Cutaneous and ocular toxicology

authors： Gündüz GU,Parmak Yener N,Kılınçel O,Gündüz C

更新日期：2018-03-01 00:00:00

abstract：PURPOSE:Evaluation of retinal and choroidal changes after energy drink consumption by optical coherence tomography and optical coherence tomography angiography. METHODS AND MATERIAL:Forty-two healthy volunteers with neither systemic nor ocular diseases were enrolled in the study. The energy drink (250 mL Red Bull ener...

journal_title：Cutaneous and ocular toxicology

authors： Doğan M,Sabaner MC,Akar AT,Şenel M,Kaşikçi İ,Günal EŞ,Özbay AE,Şarman T,Gobeka HH,Cam Ö

更新日期：2020-12-01 00:00:00

abstract：:The purpose of the present study was to measure and compare permeability coefficients (k(p)) and lag times (tau) in human skin and hairless guinea pig (HGP) skin. Paired experiments employed heat-separated epidermal membranes from human and HGP sources mounted on static in vitro diffusion cells. Infinite-dose, saturat...

journal_title：Cutaneous and ocular toxicology

authors： Frasch HF,Barbero AM

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Hydrofluoric acid (HF) is a small and partially dissociated acid (pK(a) 3.2), able to deeply penetrate into human skin in addition to the corrosiveness of the hydrogen ion (H(+)) and the toxicity of the fluoride ion (F(-)). However, there has been a lack of experimental studies to objectively characterize th...

journal_title：Cutaneous and ocular toxicology

authors： Burgher F,Mathieu L,Lati E,Gasser P,Peno-Mazzarino L,Blomet J,Hall AH,Maibach HI

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND/OBJECTIVE:Acne vulgaris is one of the most common diseases of the youth. Systemic isotretinoin is the only drug which acts on all of the etiopathogenic mechanisms of acne. Isotretinoin has some well-known side effects. Besides these, there is a suspicion whether it causes infertility or not. In this study, w...

journal_title：Cutaneous and ocular toxicology

authors： Çinar L,Kartal D,Ergin C,Aksoy H,Karadag MA,Aydin T,Cinar E,Borlu M

更新日期：2016-12-01 00:00:00

abstract：PURPOSES:To study the occurrence of ocular surface diseases on coal miners working under wells and to investigate the relation between xerophthalmia occurrence and coal dust contiguity. METHODS:To observe the influence of coal dust to ocular surface by using Schirmer to detect lacrimal gland secreting function, and br...

journal_title：Cutaneous and ocular toxicology

authors： Sun Z,Hong J,Yang D,Liu G

更新日期：2007-01-01 00:00:00

abstract：PURPOSE:The aim of this study was to determine the effects of single-dose intravitreal bevacizumab on the levels of vascular endothelial growth factor (VEGF) in serum and distant organs. METHODS:Adult New Zealand albino rabbits (n = 40) were divided into experimental and control groups. Experimental rabbits received a...

journal_title：Cutaneous and ocular toxicology

authors： Dınc E,Yıldırım O,Necat Yılmaz S,Canacankatan N,Ayaz L,Ozcan T,Temel GO

更新日期：2014-12-01 00:00:00

abstract：:Psoriasis is a common skin disorder that needs a long-term management, not only because, of its prevalence but also because of the profound impact it can have on patients quality of life. Drugs may result in exacerbation of a preexisting psoriasis, in induction of psoriatic lesions on clinically uninvolved skin in pat...

journal_title：Cutaneous and ocular toxicology

authors： Dika E,Varotti C,Bardazzi F,Maibach HI

更新日期：2006-01-01 00:00:00

abstract：:Drug-induced lichen planus has been induced by antibiotics, anticonvulsants, antidiabetics, antimalarials, antitubercular drugs, antihypertensives, psychiatric drugs, chemotherapeutic agents, diuretic, heavy metals, NSAIDs, etc. Terbinafine, an antifungal agent, is widely used for dermatophyte infections and onychomyc...

journal_title：Cutaneous and ocular toxicology

authors： Zheng Y,Zhang J,Chen H,Lai W,Maibach HI

更新日期：2017-03-01 00:00:00