Erlotinib-related keratopathy in a patient underwent laser in situ keratomileusis.

abstract：:We report a 9-month-old male patient with autoimmune enteropathy treated with intravenous methylprednisolone who developed firm, red, subcutaneous nodules 20 days after abrupt steroid interruption. The diagnosis of poststeroid panniculitis (PSP) was made based on clinical and histological grounds. PSP is an unusual co...

journal_title：Cutaneous and ocular toxicology

authors： Peralta L,Morais P,Trindade E,Barreto F,Canelhas Á,Amil J

更新日期：2012-06-01 00:00:00

abstract：PURPOSE:The aim of this study was to determine the effects of single-dose intravitreal bevacizumab on the levels of vascular endothelial growth factor (VEGF) in serum and distant organs. METHODS:Adult New Zealand albino rabbits (n = 40) were divided into experimental and control groups. Experimental rabbits received a...

journal_title：Cutaneous and ocular toxicology

authors： Dınc E,Yıldırım O,Necat Yılmaz S,Canacankatan N,Ayaz L,Ozcan T,Temel GO

更新日期：2014-12-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to investigate the antioxidant and radioprotective effects of Nigella sativa oil (NSO) and thymoquinone (TQ) against ionizing radiation-induced cataracts in lens after total cranium irradiation (IR) of rats with a single dose of 5 gray (Gy). MATERIALS AND METHODS:Seventy-four Spragu...

journal_title：Cutaneous and ocular toxicology

authors： Taysi S,Abdulrahman ZK,Okumus S,Demir E,Demir T,Akan M,Saricicek E,Saricicek V,Aksoy A,Tarakcioglu M

更新日期：2015-01-01 00:00:00

abstract：PURPOSE:The purpose of this study was to compare the neovascularization inhibiting the effect of topical bevacizumab and sorafenib and to determine the effective dose of sorafenib. MATERIAL AND METHODS:Forty-two healthy Wistar albino rats were randomly divided into six groups. The right corneas of all rats except grou...

journal_title：Cutaneous and ocular toxicology

authors： Yildirim H,Aydemir O,Balbaba M,Özercan İH,İlhan N

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:To evaluate the effect of tolterodine on pupil diameter and anterior chamber parameters, including volume, depth, and angle, with the Pentacam. METHODS:The 56 eyes of 28 patients who were diagnosed as having overactive bladder and planned to be treated with tolterodine were followed up prospectively in the ...

journal_title：Cutaneous and ocular toxicology

authors： Goktas A

更新日期：2011-03-01 00:00:00

abstract：:A snakebite is a serious and important problem in tropical and subtropical cities. A vast majority of snakebites are nonvenomous. However, venomous snakebites may cause local tissue destruction, neuroparalysis, systemic hemorrhage, generalized myotoxicity, and acute renal failure. A 10-year-old boy was brought to the ...

journal_title：Cutaneous and ocular toxicology

authors： Ozkol HU,Karadag AS,Bilgili SG,Calka O

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:Vancomycin is the gold standard in combination therapy for severe and resistant gram-positive keratitis and in particular for Methicillin-resistant Staphylococcus aureus (MRSA) infections. The aim of this study was to report the ocular surface toxicity and scoring in patients whose treatment shifted to topic...

journal_title：Cutaneous and ocular toxicology

authors： Akova Budak B,Baykara M,Kıvanç SA,Yilmaz H,Cicek S

更新日期：2016-01-01 00:00:00

abstract：PURPOSE:To evaluate the effect of anti-tubercular treatment on retinal nerve fiber layer (RNFL) thickness and the efficiency of optic coherence tomography (OCT) on early diagnosis of optic neuropathy. METHODS:Twenty patients diagnosed with either pulmonary or extra-pulmonary tuberculosis which were treated with anti-t...

journal_title：Cutaneous and ocular toxicology

authors： Gümüş A,Öner V

更新日期：2015-01-01 00:00:00

abstract：:Purpose: To investigate the efficacy and safety of intravitreal dexamethasone implant as initial and only treatment for macular oedema after pars plana vitrectomy (PPV) for rhegmatogenous retinal detachment (RRD).Methods: This study included 14 patients, who were diagnosed with macular oedema after PPV for RRD and who...

journal_title：Cutaneous and ocular toxicology

authors： Chatziralli I,Dimitriou E,Theodossiadis G,Kazantzis D,Alonistiotis D,Theodossiadis P

更新日期：2020-03-01 00:00:00

abstract：CONTEXT:Nicorandil is an antianginal drug used for 20 years in Japan and introduced in France in 1994. Since 1997, side effects such as mucocutaneous ulcerations have regularly been reported. OBJECTIVE:To describe the first case of a patient with a spontaneous corneal perforation associated with mucocutaneous ulcerati...

journal_title：Cutaneous and ocular toxicology

authors： Campolmi N,Guy C,Cinotti E,Forest F,Gain P,Philippe-Zech C,Gauthier AS,Thuret G

更新日期：2014-06-01 00:00:00

abstract：OBJECTIVE:The aim of this study is to compare the effect of prostaglandin analogues preserved with either 0.015% or 0.001% benzalkoium chloride (BAK); or 0.001% polyquad (PQ) on the ocular surface of rabbit eyes. METHODS:Forty white rabbits were randomized to receive four-times daily instillation of either 0.0015% taf...

journal_title：Cutaneous and ocular toxicology

authors： Lee HJ,Jun RM,Cho MS,Choi KR

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:The present cross-sectional study has the purpose to investigate the impact of aromatase inhibitors (AIs) on retinal nerve fiber layer (RNFL) thickness, optic nerve and macular function in patients using AIs for breast cancer treatment. METHODS:Participants in our study were 41 hormone-receptor-positive ear...

journal_title：Cutaneous and ocular toxicology

authors： Moschos MM,Chatziralli IP,Sergentanis T,Zagouri F,Chrysikos D,Ladas I,Zografos G

更新日期：2016-03-01 00:00:00

abstract：PURPOSE:The aim of this study was to evaluate and compare the toxicity of six different types of titanium dioxide (TiO2) nanoparticles (NP) on human epidermal keratinocytes (HEK). MATERIALS AND METHODS:Six TiO2 NP (A (10 nm), A*(32 nm), B (27.5 nm), C (200 nm), C*(30-40 nm), and D*(200-400 nm)) were suspended in water...

journal_title：Cutaneous and ocular toxicology

authors： Zhang LW,Monteiro-Riviere NA

更新日期：2019-03-01 00:00:00

abstract：:Psoriasis is a common skin disorder that needs a long-term management, not only because, of its prevalence but also because of the profound impact it can have on patients quality of life. Drugs may result in exacerbation of a preexisting psoriasis, in induction of psoriatic lesions on clinically uninvolved skin in pat...

journal_title：Cutaneous and ocular toxicology

authors： Dika E,Varotti C,Bardazzi F,Maibach HI

更新日期：2006-01-01 00:00:00

abstract：PURPOSE:To evaluate the efficacy of heparin eye drops in the treatment of paraquat-induced ocular surface injury. DESIGN AND METHODS:In this retrospective study, we included 25 patients (31 eyes) with paraquat-induced ocular surface injury, who attended the Affiliated Hospital of Weifang Medical University between Oct...

journal_title：Cutaneous and ocular toxicology

authors： Jian-Wei L,Xiu-Yun L,Ai-Jun D

更新日期：2017-12-01 00:00:00

abstract：CONTEXT:A number of skin diseases can be observed in chronic renal failure (CRF). Their incidence have changed in different series. OBJECTIVE:To compare the prevalence of cutaneous changes in CRF undergoing hemodialysis (HD) with healthy persons and to study the potential relationship with various parameters in the pa...

journal_title：Cutaneous and ocular toxicology

authors： Onelmis H,Sener S,Sasmaz S,Ozer A

更新日期：2012-12-01 00:00:00

abstract：:Fixed drug eruption (FDE) is a rare form of drug allergies that recur at the same cutaneous or mucosal site in every usage of drug. Single or multiple round, sharply demarcated and dusky red plaques appear soon after drug exposure. Ursodeoxycholic acid (UDCA: 3α,7β-dihydroxy-5β-cholanic acid) is used for the treatment...

journal_title：Cutaneous and ocular toxicology

authors： Ozkol HU,Calka O,Dulger AC,Bulut G

更新日期：2014-09-01 00:00:00

abstract：:This study assesses the possibility of using an in vitro model as an introduction to clinical human models for evaluating the buffering capacity of skin when an irritant is topically applied. Sodium hydroxide (NaOH) was utilized as a model base with a view to elucidate information on preventing and/or treating base-in...

journal_title：Cutaneous and ocular toxicology

authors： Ayer J,Maibach HI

更新日期：2008-01-01 00:00:00

abstract：:Drug-induced lichen planus has been induced by antibiotics, anticonvulsants, antidiabetics, antimalarials, antitubercular drugs, antihypertensives, psychiatric drugs, chemotherapeutic agents, diuretic, heavy metals, NSAIDs, etc. Terbinafine, an antifungal agent, is widely used for dermatophyte infections and onychomyc...

journal_title：Cutaneous and ocular toxicology

authors： Zheng Y,Zhang J,Chen H,Lai W,Maibach HI

更新日期：2017-03-01 00:00:00

abstract：:Purpose: We have previously reported that skin barrier function is disrupted in mice with colonic tumours induced by azoxymethane (AOM) and dextran sodium sulphate (DSS). We postulated that the impaired skin barrier function was associated with reactive oxygen species derived from gp91phox. In this study, we investiga...

journal_title：Cutaneous and ocular toxicology

authors： Yokoyama S,Hiramoto K,Yamate Y

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:The exact immunopathogenesis of contact hypersensitivity (CH) to mercury remains unclear. OBJECTIVE:The aim of the present study was to assess the role of CD4+ T cells in mercury-induced CH in mice. METHODS:Splenic CD4+ T cells obtained from nonsensitized and mercury-sensitized Balb/c mice were adoptively ...

journal_title：Cutaneous and ocular toxicology

authors： Sumiwi YA,Soesatyo MH,Sosroseno W

更新日期：2010-03-01 00:00:00

abstract：PURPOSE:Following methanol intoxication, optic nerve neuropathy may occur, which is currently treated by different therapeutic regimens. Erythropoietin (EPO) has recently been introduced as a good therapeutic option in methanol-induced optic neuropathy. The aim of the current study was to evaluate the efficacy of EPO i...

journal_title：Cutaneous and ocular toxicology

authors： Zamani N,Hassanian-Moghaddam H,Shojaei M,Rahimian S

更新日期：2018-06-01 00:00:00

abstract：:The terrifying dog in the Hound of the Baskervilles is described as having 'blazing eyes' and a 'luminous muzzle', appearances attributed by Watson and Holmes to the application of phosphorus. Review of the toxicity and flammability of white phosphorus make this improbable. It is suggested that Conan Doyle's descripti...

journal_title：Cutaneous and ocular toxicology

authors： Dayan AD

更新日期：2008-01-01 00:00:00

abstract：:In this report we present a case of erlotinib-induced trichomegaly in a male patient who received erlotinib for his pancreatic cancer. Trichomegaly as a side effect of epidermal growth factor receptor (EGFR) inhibitor therapy is uncommon in male patients. Also, it has not been reported previously in a patient with pan...

journal_title：Cutaneous and ocular toxicology

authors： Saif MW,Gnanaraj J

更新日期：2010-03-01 00:00:00

abstract：:Basal cell carcinoma (BCC), the most frequent malignant skin tumor observed in Caucasian adults, especially males, occurs mainly in sun-exposed areas of the body. BCC in the periungual tissues, such as proximal nail fold, nail matrix, nail bed and hyponychium, is rarely reported. We report a patient with two synchrono...

journal_title：Cutaneous and ocular toxicology

authors： Dika E,Patrizi A,Fanti PA,Alessandrini A,Sorci R,Piraccini BM,Vaccari S,Misciali C,Maibach HI

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:Paederus dermatitis (PD), which is an irritant contact dermatitis, is common throughout the world and caused by rove beetles. OBJECTIVES:To assess the clinical features of PD and the level of knowledge of patients from the city of Batman and surrounding areas who presented with the condition. METHODS:We de...

journal_title：Cutaneous and ocular toxicology

authors： Turan E

更新日期：2014-09-01 00:00:00

abstract：:Dermal absorption of some chemicals and drugs can cause systemic toxicity. We evaluated several case reports from the past decade, which discuss the dermal absorption of a specific chemical and potential local and systemic effects. We focused on herbicide and pesticide exposure along with exposure to cutaneous medicat...

journal_title：Cutaneous and ocular toxicology

authors： Alikhan FS,Maibach H

更新日期：2011-09-01 00:00:00

abstract：:A brief comment on efficacy and safety of propranolol in the treatment of parotid hemangioma is presented, with illustration of a typical case. ...

journal_title：Cutaneous and ocular toxicology

authors： Zheng JW

更新日期：2011-12-01 00:00:00

abstract：:Purpose: Pityriasis rosea (PR) is a common, self-limiting, inflammatory skin disease with an acute onset. The etiology of PR is not yet clearly known but the defect in the oxidation system involved in many papulosquamous skin diseases may play a role. Thiol/disulfide homeostasis is a new marker of oxidative stress and...

journal_title：Cutaneous and ocular toxicology

authors： Yüksel M,Ülfer G

更新日期：2019-12-01 00:00:00

abstract：PURPOSE:To investigate the corneal toxicity of Xalatan and three latanoprost generics using transepithelial electrical resistance (TER) and scanning electron microscopy (SEM). METHODS:Corneal TER changes after a 60-s exposure to Xalatan (latanoprost 0.005% preserved with 0.02% BAC), and latanoprost generics (Latanopro...

journal_title：Cutaneous and ocular toxicology

authors： Uematsu M,Mohamed YH,Onizuka N,Ueki R,Inoue D,Fujikawa A,Sasaki H,Kitaoka T

更新日期：2016-01-01 00:00:00