Abstract:
PURPOSES:To study the occurrence of ocular surface diseases on coal miners working under wells and to investigate the relation between xerophthalmia occurrence and coal dust contiguity. METHODS:To observe the influence of coal dust to ocular surface by using Schirmer to detect lacrimal gland secreting function, and breakup time of tear film (BUT) to evaluate the stability of lacrimal film and the quantity of lysozyme in lacrimal fluid. RESULTS:These values were lower for underground coal miners than other workers not contacting coal dust, and showed negative correlation to period of their services. CONCLUSIONS:Conditions in coal miners were worse than that of other workers. Coal dust exposure plays an important role in the development of dry eye.
journal_name
Cutan Ocul Toxicoljournal_title
Cutaneous and ocular toxicologyauthors
Sun Z,Hong J,Yang D,Liu Gdoi
10.1080/15569520701212316subject
Has Abstractpub_date
2007-01-01 00:00:00pages
257-63issue
3eissn
1556-9527issn
1556-9535pii
781181601journal_volume
26pub_type
杂志文章abstract::Rapid decontamination is vital to alleviate adverse health effects following dermal exposure to hazardous materials. There is an abundance of materials and products which can be utilised to remove hazardous materials from the skin. In this study, a total of 15 products were evaluated, 10 of which were commercial or mi...
journal_title:Cutaneous and ocular toxicology
pub_type: 杂志文章
doi:10.3109/15569527.2015.1072544
更新日期:2016-01-01 00:00:00
abstract::Fixed drug eruption (FDE) is a rare form of drug allergies that recur at the same cutaneous or mucosal site in every usage of drug. Single or multiple round, sharply demarcated and dusky red plaques appear soon after drug exposure. Ursodeoxycholic acid (UDCA: 3α,7β-dihydroxy-5β-cholanic acid) is used for the treatment...
journal_title:Cutaneous and ocular toxicology
pub_type: 杂志文章
doi:10.3109/15569527.2013.838253
更新日期:2014-09-01 00:00:00
abstract:PURPOSE:Delayed keratitis is the most dangerous ocular complication of sulfur mustard (SM) exposure. This study aimed to evaluate the role of tear and serum levels of interleukin-8 (IL-8) in SM exposed subjects. DESIGN AND METHODS:In this historical cohort study, the experimental group included 370 participants who ha...
journal_title:Cutaneous and ocular toxicology
pub_type: 杂志文章
doi:10.3109/15569527.2011.618940
更新日期:2012-06-01 00:00:00
abstract:PURPOSE:The purpose of this study was to compare the neovascularization inhibiting the effect of topical bevacizumab and sorafenib and to determine the effective dose of sorafenib. MATERIAL AND METHODS:Forty-two healthy Wistar albino rats were randomly divided into six groups. The right corneas of all rats except grou...
journal_title:Cutaneous and ocular toxicology
pub_type: 杂志文章
doi:10.1080/15569527.2020.1760877
更新日期:2020-09-01 00:00:00
abstract:CONTEXT:A number of skin diseases can be observed in chronic renal failure (CRF). Their incidence have changed in different series. OBJECTIVE:To compare the prevalence of cutaneous changes in CRF undergoing hemodialysis (HD) with healthy persons and to study the potential relationship with various parameters in the pa...
journal_title:Cutaneous and ocular toxicology
pub_type: 杂志文章
doi:10.3109/15569527.2012.657726
更新日期:2012-12-01 00:00:00
abstract::A brief comment on efficacy and safety of propranolol in the treatment of parotid hemangioma is presented, with illustration of a typical case. ...
journal_title:Cutaneous and ocular toxicology
pub_type: 评论,信件
doi:10.3109/15569527.2011.584928
更新日期:2011-12-01 00:00:00
abstract::Chemical sensitization is a serious condition caused by small reactive molecules and is characterized by a delayed type hypersensitivity known as allergic contact dermatitis (ACD). Contact with these molecules via dermal exposure represent a significant concern for chemical manufacturers. Recent legislation in the EU ...
journal_title:Cutaneous and ocular toxicology
pub_type: 杂志文章
doi:10.3109/15569527.2012.667031
更新日期:2012-12-01 00:00:00
abstract:PURPOSE:Hazelnut and birch pollen are known to destroy tear film components and attack ocular surface cells. We investigated further pollen species from different plant families, whether they show similar effects on human tear fluid and an epithelial cell line in vitro, to provide a broad basis for further research on ...
journal_title:Cutaneous and ocular toxicology
pub_type: 杂志文章
doi:10.1080/15569527.2018.1530259
更新日期:2019-03-01 00:00:00
abstract::Background: Papulopustular rash is the most common cutaneous adverse effect during targeted tumour therapy particularly with epidermal growth factor receptor inhibitors (EGFRIs). Objective: To evaluate the adverse skin reactions, mainly papulopustular rash, caused by targeted tumour therapy. Materials and methods: We ...
journal_title:Cutaneous and ocular toxicology
pub_type: 杂志文章
doi:10.1080/15569527.2019.1594874
更新日期:2019-09-01 00:00:00
abstract:OBJECTIVE:To assess the incidence of seizures induced by cycloplegic ophthalmic drops. MATERIALS AND METHODS:A survey among members of the American Association for Pediatric Ophthalmology and Strabismus yielded five patients who received cycloplegic eye drops between 1998 and 2010 and who consequently developed a seiz...
journal_title:Cutaneous and ocular toxicology
pub_type: 杂志文章
doi:10.3109/15569527.2013.808654
更新日期:2014-06-01 00:00:00
abstract:CONTEXT:Assessing the hazards of accidental exposure to toxic industrial chemical (TIC) vapors and evaluating therapeutic compounds or treatment regimens require the development of appropriate animal models. OBJECTIVE:The objective of this project was to develop an exposure system for delivering controlled vapor conce...
journal_title:Cutaneous and ocular toxicology
pub_type: 杂志文章
doi:10.3109/15569527.2013.806524
更新日期:2014-06-01 00:00:00
abstract::The Organisation for Economic Co-operation and Development (OECD) Test Guideline 429 for the local lymph node assay (LLNA) indicates a minimum of 4 mice per dose group, or of 5 mice if statistics are required. Recent discussions at the Interagency Coordinating Committee for the Validation of Alternative Methods (ICCVA...
journal_title:Cutaneous and ocular toxicology
pub_type: 杂志文章,评审
doi:10.1080/15569520802636280
更新日期:2009-01-01 00:00:00
abstract::The purpose of the present study was to measure and compare permeability coefficients (k(p)) and lag times (tau) in human skin and hairless guinea pig (HGP) skin. Paired experiments employed heat-separated epidermal membranes from human and HGP sources mounted on static in vitro diffusion cells. Infinite-dose, saturat...
journal_title:Cutaneous and ocular toxicology
pub_type: 杂志文章
doi:10.1080/15569520902950474
更新日期:2009-01-01 00:00:00
abstract:PURPOSE:To assess the long-term intraocular pressure (IOP) changes after the intravitreal injection of bevacizumab (Avastin; Genentech, Inc., South San Francisco, CA) for treatment of age-related macular degeneration (AMD) and diabetic macular edema (DME) patients and evaluate the correlation factors. MATERIAL AND MET...
journal_title:Cutaneous and ocular toxicology
pub_type: 临床试验,杂志文章
doi:10.3109/15569527.2015.1124886
更新日期:2016-12-01 00:00:00
abstract::A snakebite is a serious and important problem in tropical and subtropical cities. A vast majority of snakebites are nonvenomous. However, venomous snakebites may cause local tissue destruction, neuroparalysis, systemic hemorrhage, generalized myotoxicity, and acute renal failure. A 10-year-old boy was brought to the ...
journal_title:Cutaneous and ocular toxicology
pub_type: 杂志文章
doi:10.3109/15569527.2011.573832
更新日期:2011-12-01 00:00:00
abstract::Context Incontinence-associated dermatitis (IAD) is a type of moisture-associated dermatitis caused by repeated skin exposure to urine or stool. A product that could mitigate such symptoms would have a significant impact on cost of care and patients' quality of life. Objective This study compared the clinical efficacy...
journal_title:Cutaneous and ocular toxicology
pub_type: 临床试验,杂志文章
doi:10.1080/15569527.2016.1257637
更新日期:2017-09-01 00:00:00
abstract:PURPOSE:To evaluate the treatment of autologous serum eye drops (ASED) on dry eyes in patients with graft-versus-host disease (GVHD). METHODS:A retrospective chart review of 35 patients with a history of ocular GVHD following hematopoietic stem cell transplantation that used ASED to alleviate dry eye symptoms was perf...
journal_title:Cutaneous and ocular toxicology
pub_type: 杂志文章
doi:10.1080/15569527.2016.1209770
更新日期:2017-06-01 00:00:00
abstract::Basal cell carcinoma (BCC), the most frequent malignant skin tumor observed in Caucasian adults, especially males, occurs mainly in sun-exposed areas of the body. BCC in the periungual tissues, such as proximal nail fold, nail matrix, nail bed and hyponychium, is rarely reported. We report a patient with two synchrono...
journal_title:Cutaneous and ocular toxicology
pub_type: 杂志文章
doi:10.3109/15569527.2012.708956
更新日期:2013-06-01 00:00:00
abstract:PURPOSE:Warfarin (WF) is an anticoagulant which also affects physiological processes other than hemostasis. Our previous investigations showed the effect of WF which gained access to the organism via skin on resting peripheral blood granulocytes. Based on these data, the aim of the present study was to examine whether ...
journal_title:Cutaneous and ocular toxicology
pub_type: 杂志文章
doi:10.1080/15569527.2016.1275664
更新日期:2017-09-01 00:00:00
abstract:CONTEXT:Nicorandil is an antianginal drug used for 20 years in Japan and introduced in France in 1994. Since 1997, side effects such as mucocutaneous ulcerations have regularly been reported. OBJECTIVE:To describe the first case of a patient with a spontaneous corneal perforation associated with mucocutaneous ulcerati...
journal_title:Cutaneous and ocular toxicology
pub_type: 杂志文章
doi:10.3109/15569527.2013.812105
更新日期:2014-06-01 00:00:00
abstract::Patch testing is an important tool in the diagnosis of allergic contact dermatitis. Although this technique can be accurate, occasionally the results may be inconclusive. A previously positive result to an allergen may become negative upon repeat testing, and this may complicate the process of achieving a definitive d...
journal_title:Cutaneous and ocular toxicology
pub_type: 杂志文章
doi:10.1080/15569520701856757
更新日期:2008-01-01 00:00:00
abstract::Purpose: Pityriasis rosea (PR) is a common, self-limiting, inflammatory skin disease with an acute onset. The etiology of PR is not yet clearly known but the defect in the oxidation system involved in many papulosquamous skin diseases may play a role. Thiol/disulfide homeostasis is a new marker of oxidative stress and...
journal_title:Cutaneous and ocular toxicology
pub_type: 杂志文章
doi:10.1080/15569527.2019.1616748
更新日期:2019-12-01 00:00:00
abstract:BACKGROUND/OBJECTIVE:Acne vulgaris is one of the most common diseases of the youth. Systemic isotretinoin is the only drug which acts on all of the etiopathogenic mechanisms of acne. Isotretinoin has some well-known side effects. Besides these, there is a suspicion whether it causes infertility or not. In this study, w...
journal_title:Cutaneous and ocular toxicology
pub_type: 临床试验,杂志文章
doi:10.3109/15569527.2015.1119839
更新日期:2016-12-01 00:00:00
abstract:BACKGROUND:Hydrofluoric acid (HF) is a small and partially dissociated acid (pK(a) 3.2), able to deeply penetrate into human skin in addition to the corrosiveness of the hydrogen ion (H(+)) and the toxicity of the fluoride ion (F(-)). However, there has been a lack of experimental studies to objectively characterize th...
journal_title:Cutaneous and ocular toxicology
pub_type: 杂志文章
doi:10.3109/15569527.2010.534748
更新日期:2011-06-01 00:00:00
abstract::We report a case of iris atrophy and corneal endothelial decompensation following the inadvertent use of water-based ink for capsular staining during cataract surgery. The anterior chamber was thoroughly irrigated with balanced salt solution after the identification of the wrong dye. Phacoemulsification with minimal u...
journal_title:Cutaneous and ocular toxicology
pub_type: 杂志文章
doi:10.3109/15569520903280129
更新日期:2009-01-01 00:00:00
abstract::Dicyclohexylcarbodiimide (DCC) and Diisopropylcarbodiimide (DIC) are two representative chemicals in the carbodiimide class of chemicals used in industry as stabilizing agents. There is a potential of dermal exposure to these agents in chemical, pharmaceutical and recombinant DNA industries. The National Toxicology Pr...
journal_title:Cutaneous and ocular toxicology
pub_type: 杂志文章
doi:10.3109/15569527.2011.629384
更新日期:2012-09-01 00:00:00
abstract::Skin patch testing of menses and venous blood on the vulva (labia majora) and the upper arm was performed to assess the potential contribution of these biological fluids to vulvar irritation during menstruation. After 24 and 48 hours of occlusive exposure, the skin of the labia majora was relatively unaffected by thes...
journal_title:Cutaneous and ocular toxicology
pub_type: 杂志文章
doi:10.1080/15569520500371735
更新日期:2005-01-01 00:00:00
abstract::Drug-induced lichen planus has been induced by antibiotics, anticonvulsants, antidiabetics, antimalarials, antitubercular drugs, antihypertensives, psychiatric drugs, chemotherapeutic agents, diuretic, heavy metals, NSAIDs, etc. Terbinafine, an antifungal agent, is widely used for dermatophyte infections and onychomyc...
journal_title:Cutaneous and ocular toxicology
pub_type: 杂志文章
doi:10.3109/15569527.2016.1160101
更新日期:2017-03-01 00:00:00
abstract:BACKGROUND:To evaluate the effect of tolterodine on pupil diameter and anterior chamber parameters, including volume, depth, and angle, with the Pentacam. METHODS:The 56 eyes of 28 patients who were diagnosed as having overactive bladder and planned to be treated with tolterodine were followed up prospectively in the ...
journal_title:Cutaneous and ocular toxicology
pub_type: 杂志文章
doi:10.3109/15569527.2010.523036
更新日期:2011-03-01 00:00:00
abstract:BACKGROUND:The present cross-sectional study has the purpose to investigate the impact of aromatase inhibitors (AIs) on retinal nerve fiber layer (RNFL) thickness, optic nerve and macular function in patients using AIs for breast cancer treatment. METHODS:Participants in our study were 41 hormone-receptor-positive ear...
journal_title:Cutaneous and ocular toxicology
pub_type: 杂志文章
doi:10.3109/15569527.2014.1003267
更新日期:2016-03-01 00:00:00