The effect of systemic isotretinoin on male fertility.

abstract：:The terrifying dog in the Hound of the Baskervilles is described as having 'blazing eyes' and a 'luminous muzzle', appearances attributed by Watson and Holmes to the application of phosphorus. Review of the toxicity and flammability of white phosphorus make this improbable. It is suggested that Conan Doyle's descripti...

journal_title：Cutaneous and ocular toxicology

authors： Dayan AD

更新日期：2008-01-01 00:00:00

abstract：:Lichenoid drug eruption (LDE) is a common cutaneous side effect of drugs including antimalarials, antihypertensives, nonsteroids, anti-inflammatory drugs and diuretics. The physiopathologic relationship between colchicine treatment and LDE is unclear. There is very little documentation of LDE induced by colchicine in ...

journal_title：Cutaneous and ocular toxicology

authors： An I,Demir V,Akdeniz S

更新日期：2017-06-01 00:00:00

abstract：:Erythema multiforme (EM) is an immune-mediated mucocutaneous eruption characterized by symmetrically distributed, polymorphic targetoid lesions, mostly on the distal parts of the extremities. It occurs mostly in the setting of an infection in certain predisposed individuals. A 30-year-old pregnant woman was presented ...

journal_title：Cutaneous and ocular toxicology

authors： Özyurt S,Er O,Afsar FS,Ermete M

更新日期：2013-09-01 00:00:00

abstract：:The bullous hemorrhagic dermatosis induced by enoxaparin is a rare adverse reaction, which may be under-reported given its favorable evolution. We report a 71-year-old man who developed hemorrhagic bullae at sites distant from subcutaneous enoxaparin injections. It is important that clinicians be aware of the differen...

journal_title：Cutaneous and ocular toxicology

authors： Gouveia AI,Lopes L,Soares-Almeida L,Filipe P

更新日期：2016-01-01 00:00:00

abstract：:The most common adverse effects of oral isotretinoin (>1/10) are: cheilitis, skin dryness, erythema, itching, scaling, bruising, skin atopy, conjunctivitis, dry eyes and eyelid inflammation. The aim of this work was to define an optimal dose regime of the oral isotretinoin allowing for effective reduction of sebum pro...

journal_title：Cutaneous and ocular toxicology

authors： Bergler-Czop B,Brzezińska-Wcisło L

更新日期：2012-09-01 00:00:00

abstract：:Purpose: To investigate the efficacy and safety of intravitreal dexamethasone implant as initial and only treatment for macular oedema after pars plana vitrectomy (PPV) for rhegmatogenous retinal detachment (RRD).Methods: This study included 14 patients, who were diagnosed with macular oedema after PPV for RRD and who...

journal_title：Cutaneous and ocular toxicology

authors： Chatziralli I,Dimitriou E,Theodossiadis G,Kazantzis D,Alonistiotis D,Theodossiadis P

更新日期：2020-03-01 00:00:00

abstract：:Context Incontinence-associated dermatitis (IAD) is a type of moisture-associated dermatitis caused by repeated skin exposure to urine or stool. A product that could mitigate such symptoms would have a significant impact on cost of care and patients' quality of life. Objective This study compared the clinical efficacy...

journal_title：Cutaneous and ocular toxicology

authors： Matar H,Larner J,Viegas V,Kansagra S,Atkinson KL,Shetage S,Skamarauskas JT,Theivendran B,Goldman VS,Chilcott RP

更新日期：2017-09-01 00:00:00

abstract：:Drug-induced lichen planus has been induced by antibiotics, anticonvulsants, antidiabetics, antimalarials, antitubercular drugs, antihypertensives, psychiatric drugs, chemotherapeutic agents, diuretic, heavy metals, NSAIDs, etc. Terbinafine, an antifungal agent, is widely used for dermatophyte infections and onychomyc...

journal_title：Cutaneous and ocular toxicology

authors： Zheng Y,Zhang J,Chen H,Lai W,Maibach HI

更新日期：2017-03-01 00:00:00

abstract：:Attempts to improve formulation of topical products are a continuing process and the development of micro- and nanovesicular systems as well as polymeric microparticles has led to marketing of topical drugs and cosmetics using these technologies. Encapsulation of some well-known contact allergens in ethanolic liposome...

journal_title：Cutaneous and ocular toxicology

authors： Madsen JT,Vogel S,Johansen JD,Andersen KE

更新日期：2011-06-01 00:00:00

abstract：OBJECTIVE:To investigate the effects of topiramate on choroidal thickness and anterior chamber parameters using optical coherence tomography in the treatment of patients with migraine. METHODS:A total of 22 eyes of 22 adults (12 females, 10 males) diagnosed with migraine and scheduled to topiramate treatment for pain ...

journal_title：Cutaneous and ocular toxicology

authors： Gok M,Ozdemir O

更新日期：2017-12-01 00:00:00

abstract：:This study assesses the possibility of using an in vitro model as an introduction to clinical human models for evaluating the buffering capacity of skin when an irritant is topically applied. Sodium hydroxide (NaOH) was utilized as a model base with a view to elucidate information on preventing and/or treating base-in...

journal_title：Cutaneous and ocular toxicology

authors： Ayer J,Maibach HI

更新日期：2008-01-01 00:00:00

abstract：PURPOSE:To evaluate antioxidant effects of active vitamin D (calcitriol) against high-dose radioiodine (RAI) therapy-associated damage of lacrimal gland. MATERIALS AND METHODS:Wistar albino rats were used and divided into three groups randomly (n = 12/group). The first group was appointed as the negative control group...

journal_title：Cutaneous and ocular toxicology

authors： Eksioglu U,Atilgan HI,Yakin M,Yazihan N,Altiparmak UE,Yumusak N,Korkmaz M,Demir A,Ornek F,Aribal Ayral P,Koca G

更新日期：2019-03-01 00:00:00

abstract：:Rapid decontamination is vital to alleviate adverse health effects following dermal exposure to hazardous materials. There is an abundance of materials and products which can be utilised to remove hazardous materials from the skin. In this study, a total of 15 products were evaluated, 10 of which were commercial or mi...

journal_title：Cutaneous and ocular toxicology

authors： Matar H,Guerreiro A,Piletsky SA,Price SC,Chilcott RP

更新日期：2016-01-01 00:00:00

abstract：PURPOSE:Delayed keratitis is the most dangerous ocular complication of sulfur mustard (SM) exposure. This study aimed to evaluate the role of tear and serum levels of interleukin-8 (IL-8) in SM exposed subjects. DESIGN AND METHODS:In this historical cohort study, the experimental group included 370 participants who ha...

journal_title：Cutaneous and ocular toxicology

authors： Ghasemi H,Ghazanfari T,Yaraee R,Pourfarzam S,Soroush MR,Faghihzadeh S,Babaei M,Naghizadeh MM,Mohammad Hassan Z

更新日期：2012-06-01 00:00:00

abstract：:Erlotinib is a tyrosine kinase inhibitor of the epidermal growth factor receptor. Since there is a wide expression of the epidermal growth factor receptors in the epithelial tissues of ocular surface and adnexa, ocular adverse reactions may happen during systemic administration of erlotinib. Previously reported ocular...

journal_title：Cutaneous and ocular toxicology

authors： Kau HC,Tsai CC

更新日期：2016-09-01 00:00:00

abstract：OBJECTIVE:To assess the incidence of seizures induced by cycloplegic ophthalmic drops. MATERIALS AND METHODS:A survey among members of the American Association for Pediatric Ophthalmology and Strabismus yielded five patients who received cycloplegic eye drops between 1998 and 2010 and who consequently developed a seiz...

journal_title：Cutaneous and ocular toxicology

authors： Wygnanski-Jaffe T,Nucci P,Goldchmit M,Mezer E

更新日期：2014-06-01 00:00:00

abstract：PURPOSE:To evaluate the effect of anti-tubercular treatment on retinal nerve fiber layer (RNFL) thickness and the efficiency of optic coherence tomography (OCT) on early diagnosis of optic neuropathy. METHODS:Twenty patients diagnosed with either pulmonary or extra-pulmonary tuberculosis which were treated with anti-t...

journal_title：Cutaneous and ocular toxicology

authors： Gümüş A,Öner V

更新日期：2015-01-01 00:00:00

abstract：:The anti-inflammatory properties of topical corticosteroids are well documented; additionally, their sensitization potential is also known. We aimed to assess the relative sensitization potential of hydrocortisone and tixocortol pivalate in an animal assay as it relates to potential for sensitization in humans. Using ...

journal_title：Cutaneous and ocular toxicology

authors： Mirshahpanah P,Maibach HI

更新日期：2007-01-01 00:00:00

abstract：PURPOSE:To find the abnormalities in various retinal layers caused by radiation retinopathy using spectral domain optical coherence tomography (SD-OCT). METHODS:We report a case of radiation retinopathy that was imaged using SD-OCT Copernicus (Optopol, Zawiercie, Poland). Analysis and synthesis of the OCT image were d...

journal_title：Cutaneous and ocular toxicology

authors： Raman R,Pal SS,Krishnan T,Laxmi G,Radke N,Sharma T

更新日期：2010-03-01 00:00:00

abstract：PURPOSE:Following methanol intoxication, optic nerve neuropathy may occur, which is currently treated by different therapeutic regimens. Erythropoietin (EPO) has recently been introduced as a good therapeutic option in methanol-induced optic neuropathy. The aim of the current study was to evaluate the efficacy of EPO i...

journal_title：Cutaneous and ocular toxicology

authors： Zamani N,Hassanian-Moghaddam H,Shojaei M,Rahimian S

更新日期：2018-06-01 00:00:00

abstract：PURPOSE:Warfarin (WF) is an anticoagulant which also affects physiological processes other than hemostasis. Our previous investigations showed the effect of WF which gained access to the organism via skin on resting peripheral blood granulocytes. Based on these data, the aim of the present study was to examine whether ...

journal_title：Cutaneous and ocular toxicology

authors： Mirkov I,Popov Aleksandrov A,Demenesku J,Ninkov M,Mileusnic D,Kataranovski D,Kataranovski M

更新日期：2017-09-01 00:00:00

abstract：CONTEXT:The acute effects of cigarette smoking on pupil size and ocular wavefront aberrations (OWA) have been previously documented. The accommodation status of the eye is well known to be related to ocular aberrations. No previous study has evaluated the impact of cigarette smoking on the accommodation status of the e...

journal_title：Cutaneous and ocular toxicology

authors： Bardak H,Gunay M,Bardak Y,Ercalik Y,Imamoglu S,Yildiz E,Gunay BO

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:The present cross-sectional study has the purpose to investigate the impact of aromatase inhibitors (AIs) on retinal nerve fiber layer (RNFL) thickness, optic nerve and macular function in patients using AIs for breast cancer treatment. METHODS:Participants in our study were 41 hormone-receptor-positive ear...

journal_title：Cutaneous and ocular toxicology

authors： Moschos MM,Chatziralli IP,Sergentanis T,Zagouri F,Chrysikos D,Ladas I,Zografos G

更新日期：2016-03-01 00:00:00

abstract：:The Organisation for Economic Co-operation and Development (OECD) Test Guideline 429 for the local lymph node assay (LLNA) indicates a minimum of 4 mice per dose group, or of 5 mice if statistics are required. Recent discussions at the Interagency Coordinating Committee for the Validation of Alternative Methods (ICCVA...

journal_title：Cutaneous and ocular toxicology

authors： Basketter DA,Dearman RJ,Kimber I,Gerberick GF,Ryan CA

更新日期：2009-01-01 00:00:00

abstract：:The skin is a major exposure route for many potentially toxic chemicals. It is, therefore, important to be able to predict the permeability of compounds through skin under a variety of conditions. Available skin permeability databases are often limited in scope and not conducive to developing effective models. This sp...

journal_title：Cutaneous and ocular toxicology

authors： Keshwani DR,Jones DD,Brand RM

更新日期：2005-01-01 00:00:00

abstract：:A brief comment on efficacy and safety of propranolol in the treatment of parotid hemangioma is presented, with illustration of a typical case. ...

journal_title：Cutaneous and ocular toxicology

authors： Zheng JW

更新日期：2011-12-01 00:00:00

abstract：PURPOSE:To evaluate the short- and long-term effects of selective serotonin reuptake inhibitors (SSRIs) on intraocular pressure (IOP) and anterior segment parameters in open angle eyes. MATERIALS AND METHODS:This cross-sectional study included 325 eyes of 166 subjects. Subjects were divided into three groups: Group 1 ...

journal_title：Cutaneous and ocular toxicology

authors： Gündüz GU,Parmak Yener N,Kılınçel O,Gündüz C

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:The massive uptake of compatible osmolytes is a self-protective response shared by retina exposed to hypertonic stress and ultraviolet stress. OBJECTIVE:This study aimed to investigate the protective effects of taurine against ultraviolet damage in human retinal pigment epithelium cells. METHODS:Real-time ...

journal_title：Cutaneous and ocular toxicology

authors： Dayang W,Jinsong Z

更新日期：2015-01-01 00:00:00

abstract：PURPOSE:To assess the long-term intraocular pressure (IOP) changes after the intravitreal injection of bevacizumab (Avastin; Genentech, Inc., South San Francisco, CA) for treatment of age-related macular degeneration (AMD) and diabetic macular edema (DME) patients and evaluate the correlation factors. MATERIAL AND MET...

journal_title：Cutaneous and ocular toxicology

authors： Baek SU,Park IW,Suh W

更新日期：2016-12-01 00:00:00

abstract：:The authors provide a framework for working up and counseling a patient with suspected textile dermatitis, focusing on identifying which textile materials are most likely to be the cause of the eczematous lesions, the current clinical guidelines, the utility and appropriateness of patch testing, the limitations of the...

journal_title：Cutaneous and ocular toxicology

authors： Coman G,Blickenstaff N,Edwards A,Maibach H

更新日期：2015-03-01 00:00:00