High-resolution optical coherence tomography correlates in ischemic radiation retinopathy.

Abstract:

PURPOSE:To find the abnormalities in various retinal layers caused by radiation retinopathy using spectral domain optical coherence tomography (SD-OCT). METHODS:We report a case of radiation retinopathy that was imaged using SD-OCT Copernicus (Optopol, Zawiercie, Poland). Analysis and synthesis of the OCT image were done using information both at the fovea and 2.5 mm temporal to the fovea. RESULTS:The layers that were reduced in thickness included the inner plexiform layer (47 microm vs. 74 microm), the inner nuclear layer (17 microm vs. 48 microm), and the outer plexiform layer (25 microm vs. 45 microm), whereas the layers with comparable thickness included the nerve fiber layer (24 microm vs. 25 microm), the outer nuclear layer (42 microm vs. 43 microm), the outer segment-inner segment junction (52 microm vs. 54 microm), and the retinal pigment epithelium (RPE) choriocapillaris layer (30 microm vs. 28 microm). CONCLUSION:This report suggests that the radiation-induced damage was confined to the inner layers of the retina. However, secondary outer retinal layer changes may also occur, as suggested by functional derangements.

journal_name

Cutan Ocul Toxicol

authors

Raman R,Pal SS,Krishnan T,Laxmi G,Radke N,Sharma T

doi

10.3109/15569520903331674

subject

Has Abstract

pub_date

2010-03-01 00:00:00

pages

57-61

issue

1

eissn

1556-9527

issn

1556-9535

journal_volume

29

pub_type

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