Epithelial healing in experimental corneal alkali wounds with nondiluted autologous serum eye drops.

abstract：PURPOSE:The aim of this study was to evaluate and compare the toxicity of six different types of titanium dioxide (TiO2) nanoparticles (NP) on human epidermal keratinocytes (HEK). MATERIALS AND METHODS:Six TiO2 NP (A (10 nm), A*(32 nm), B (27.5 nm), C (200 nm), C*(30-40 nm), and D*(200-400 nm)) were suspended in water...

journal_title：Cutaneous and ocular toxicology

authors： Zhang LW,Monteiro-Riviere NA

更新日期：2019-03-01 00:00:00

abstract：:The most common adverse effects of oral isotretinoin (>1/10) are: cheilitis, skin dryness, erythema, itching, scaling, bruising, skin atopy, conjunctivitis, dry eyes and eyelid inflammation. The aim of this work was to define an optimal dose regime of the oral isotretinoin allowing for effective reduction of sebum pro...

journal_title：Cutaneous and ocular toxicology

authors： Bergler-Czop B,Brzezińska-Wcisło L

更新日期：2012-09-01 00:00:00

abstract：:We report a case of ophthalmic antibiotic ointment in the anterior chamber following uneventful phacoemulsification surgery. Antibiotic ointment was observed in the superior angle beneath the clear corneal wound one month later. The patient remained asymptomatic for 26 months after surgery until mild iritis developed....

journal_title：Cutaneous and ocular toxicology

authors： Ugurbas SC,Akova YA

更新日期：2010-09-01 00:00:00

abstract：PURPOSE:To evaluate antioxidant effects of active vitamin D (calcitriol) against high-dose radioiodine (RAI) therapy-associated damage of lacrimal gland. MATERIALS AND METHODS:Wistar albino rats were used and divided into three groups randomly (n = 12/group). The first group was appointed as the negative control group...

journal_title：Cutaneous and ocular toxicology

authors： Eksioglu U,Atilgan HI,Yakin M,Yazihan N,Altiparmak UE,Yumusak N,Korkmaz M,Demir A,Ornek F,Aribal Ayral P,Koca G

更新日期：2019-03-01 00:00:00

abstract：:The assessment of the potency of a skin sensitizing chemical is a key starting point for its subsequent risk assessment/management. The Local Lymph Node Assay can provide information on the relative skin sensitizing potency of contact allergens by interpolation from the dose response curve the concentration of a chemi...

journal_title：Cutaneous and ocular toxicology

authors： Ryan CA,Chaney JG,Gerberick GF,Kern PS,Dearman RJ,Kimber I,Basketter DA

更新日期：2007-01-01 00:00:00

abstract：OBJECTIVE:The aim of this study is to compare the effect of prostaglandin analogues preserved with either 0.015% or 0.001% benzalkoium chloride (BAK); or 0.001% polyquad (PQ) on the ocular surface of rabbit eyes. METHODS:Forty white rabbits were randomized to receive four-times daily instillation of either 0.0015% taf...

journal_title：Cutaneous and ocular toxicology

authors： Lee HJ,Jun RM,Cho MS,Choi KR

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Hydrofluoric acid (HF) is a small and partially dissociated acid (pK(a) 3.2), able to deeply penetrate into human skin in addition to the corrosiveness of the hydrogen ion (H(+)) and the toxicity of the fluoride ion (F(-)). However, there has been a lack of experimental studies to objectively characterize th...

journal_title：Cutaneous and ocular toxicology

authors： Burgher F,Mathieu L,Lati E,Gasser P,Peno-Mazzarino L,Blomet J,Hall AH,Maibach HI

更新日期：2011-06-01 00:00:00

abstract：:Purpose: Pityriasis rosea (PR) is a common, self-limiting, inflammatory skin disease with an acute onset. The etiology of PR is not yet clearly known but the defect in the oxidation system involved in many papulosquamous skin diseases may play a role. Thiol/disulfide homeostasis is a new marker of oxidative stress and...

journal_title：Cutaneous and ocular toxicology

authors： Yüksel M,Ülfer G

更新日期：2019-12-01 00:00:00

abstract：INTRODUCTION:Sulfur mustard (SM) has been used as a dangerous chemical warfare agent since the early 20th century. Although many descriptive studies about SM-induced ocular injuries are present in the medical literature, few of them have been conducted over a large group with serious ocular involvement. MATERIALS AND ...

journal_title：Cutaneous and ocular toxicology

authors： Ghasemi H,Ghazanfari T,Ghassemi-Broumand M,Javadi MA,Babaei M,Soroush MR,Yaraee R,Faghihzadeh S,Poorfarzam S,Owlia P,Naghizadeh MM,Etezad-Razavi M,Jadidi K,Naderi M,Hassan ZM

更新日期：2009-01-01 00:00:00

abstract：OBJECTIVE:To describe 8 cases of toxic keratopathy due to abuse of topical anesthetic drugs. METHODS:Clinical findings from patients with toxic keratopathy were investigated retrospectively. RESULTS:Two patients had toxic keratopathy bilaterally. Five of 8 patients had an ocular history of a corneal foreign body, 1 h...

journal_title：Cutaneous and ocular toxicology

authors： Yeniad B,Canturk S,Esin Ozdemir F,Alparslan N,Akarcay K

更新日期：2010-06-01 00:00:00

abstract：:Ciliary body is responsible for humour aqueous production in posterior chamber. Valproic acid (VPA) has been widely used for the treatment of epilepsy and other neuropsychiatric diseases such as bipolar disease and major depression. Oxcarbazepine (OXC) is a new anti-epileptic agent that has been used recently for chil...

journal_title：Cutaneous and ocular toxicology

authors： Göktaş G,Aktaş Z,Erdoğan D,Seymen CM,Karaca EE,Cansu A,Serdaroğlu A,Kaplanoğlu GT

更新日期：2015-01-01 00:00:00

abstract：:Drug-induced lichen planus has been induced by antibiotics, anticonvulsants, antidiabetics, antimalarials, antitubercular drugs, antihypertensives, psychiatric drugs, chemotherapeutic agents, diuretic, heavy metals, NSAIDs, etc. Terbinafine, an antifungal agent, is widely used for dermatophyte infections and onychomyc...

journal_title：Cutaneous and ocular toxicology

authors： Zheng Y,Zhang J,Chen H,Lai W,Maibach HI

更新日期：2017-03-01 00:00:00

abstract：CONTEXT:The acute effects of cigarette smoking on pupil size and ocular wavefront aberrations (OWA) have been previously documented. The accommodation status of the eye is well known to be related to ocular aberrations. No previous study has evaluated the impact of cigarette smoking on the accommodation status of the e...

journal_title：Cutaneous and ocular toxicology

authors： Bardak H,Gunay M,Bardak Y,Ercalik Y,Imamoglu S,Yildiz E,Gunay BO

更新日期：2017-03-01 00:00:00

abstract：:A 63-year-old female with history of a resected frontal lobe meningioma presented with bilaterally decreased vision after a bite from a brown recluse spider. The exam was significant for a left relative afferent pupillary defect, bilateral optic nerve pallor, decreased foveal sensitivity in the left eye and new bilate...

journal_title：Cutaneous and ocular toxicology

authors： Mantopoulos D,Hendershot AJ,Cebulla CM,Hirsh DK

更新日期：2016-01-01 00:00:00

abstract：PURPOSE:The aim of this study was to examine the effects of long-term use of hydroxychloroquine (HQ) on the pachymetric, aberrometric, and densitometric values of the cornea and corneal endothelium in lupus patients. METHOD:Twenty-two eyes (study group) of 22 patients using HQ for treatment of lupus and 25 eyes (contr...

journal_title：Cutaneous and ocular toxicology

authors： Çağlayan M,Akyol L,Balcı MA,Öncül H,Alakuş MF,Dağ U

更新日期：2020-12-23 00:00:00

abstract：:We report a case of iris atrophy and corneal endothelial decompensation following the inadvertent use of water-based ink for capsular staining during cataract surgery. The anterior chamber was thoroughly irrigated with balanced salt solution after the identification of the wrong dye. Phacoemulsification with minimal u...

journal_title：Cutaneous and ocular toxicology

authors： Kugu S,Erdogan G,Kandemir B,Dogan OK

更新日期：2009-01-01 00:00:00

abstract：:There is a concern that peptides in cosmetic creams marketed as anti-aging/anti-wrinkle may penetrate into the deep layers of the skin and potentially stimulate biological activity. Claims for one cosmetic peptide, acetyl hexapeptide-8 (Ac-EEMQRR-amide), suggest interference with neuromuscular signaling as its anti-wr...

journal_title：Cutaneous and ocular toxicology

authors： Kraeling ME,Zhou W,Wang P,Ogunsola OA

更新日期：2015-03-01 00:00:00

abstract：:The purpose of the present study was to measure and compare permeability coefficients (k(p)) and lag times (tau) in human skin and hairless guinea pig (HGP) skin. Paired experiments employed heat-separated epidermal membranes from human and HGP sources mounted on static in vitro diffusion cells. Infinite-dose, saturat...

journal_title：Cutaneous and ocular toxicology

authors： Frasch HF,Barbero AM

更新日期：2009-01-01 00:00:00

abstract：:The anti-inflammatory properties of topical corticosteroids are well documented; additionally, their sensitization potential is also known. We aimed to assess the relative sensitization potential of hydrocortisone and tixocortol pivalate in an animal assay as it relates to potential for sensitization in humans. Using ...

journal_title：Cutaneous and ocular toxicology

authors： Mirshahpanah P,Maibach HI

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Systemic isotretinoin (13-cis-retinoic acid) is effective in the treatment of acne vulgaris. The most common side effects are mucocutaneous ones. Hematuria seen secondary to isotretinoin treatment is thought to be due to mucosal dryness in the urinary system. This study aims to determine the frequency of hem...

journal_title：Cutaneous and ocular toxicology

authors： Yesilkaya B,Alli N,Artuz RF,Ulu E,Kartal D,Cinar SL

更新日期：2017-03-01 00:00:00

abstract：OBJECTIVE:To investigate the effects of topiramate on choroidal thickness and anterior chamber parameters using optical coherence tomography in the treatment of patients with migraine. METHODS:A total of 22 eyes of 22 adults (12 females, 10 males) diagnosed with migraine and scheduled to topiramate treatment for pain ...

journal_title：Cutaneous and ocular toxicology

authors： Gok M,Ozdemir O

更新日期：2017-12-01 00:00:00

abstract：:The most common side effects of interferon-beta therapy following subcutaneous administration include pain, inflammation and induration at the injection site, which occur in approximately 20-60% of patients. Besides, transient injection-site erythema is frequently seen in beta-interferon therapy. Less frequent reactio...

journal_title：Cutaneous and ocular toxicology

authors： Ozuguz P,Kacar SD,Karaca S,Tokyol C

更新日期：2014-12-01 00:00:00

abstract：:Psoriasis is a common skin disorder that needs a long-term management, not only because, of its prevalence but also because of the profound impact it can have on patients quality of life. Drugs may result in exacerbation of a preexisting psoriasis, in induction of psoriatic lesions on clinically uninvolved skin in pat...

journal_title：Cutaneous and ocular toxicology

authors： Dika E,Varotti C,Bardazzi F,Maibach HI

更新日期：2006-01-01 00:00:00

abstract：:In this report we present a case of erlotinib-induced trichomegaly in a male patient who received erlotinib for his pancreatic cancer. Trichomegaly as a side effect of epidermal growth factor receptor (EGFR) inhibitor therapy is uncommon in male patients. Also, it has not been reported previously in a patient with pan...

journal_title：Cutaneous and ocular toxicology

authors： Saif MW,Gnanaraj J

更新日期：2010-03-01 00:00:00

abstract：:Erlotinib is a tyrosine kinase inhibitor of the epidermal growth factor receptor. Since there is a wide expression of the epidermal growth factor receptors in the epithelial tissues of ocular surface and adnexa, ocular adverse reactions may happen during systemic administration of erlotinib. Previously reported ocular...

journal_title：Cutaneous and ocular toxicology

authors： Kau HC,Tsai CC

更新日期：2016-09-01 00:00:00

abstract：:Context Incontinence-associated dermatitis (IAD) is a type of moisture-associated dermatitis caused by repeated skin exposure to urine or stool. A product that could mitigate such symptoms would have a significant impact on cost of care and patients' quality of life. Objective This study compared the clinical efficacy...

journal_title：Cutaneous and ocular toxicology

authors： Matar H,Larner J,Viegas V,Kansagra S,Atkinson KL,Shetage S,Skamarauskas JT,Theivendran B,Goldman VS,Chilcott RP

更新日期：2017-09-01 00:00:00

abstract：PURPOSE:To investigate the corneal toxicity of Xalatan and three latanoprost generics using transepithelial electrical resistance (TER) and scanning electron microscopy (SEM). METHODS:Corneal TER changes after a 60-s exposure to Xalatan (latanoprost 0.005% preserved with 0.02% BAC), and latanoprost generics (Latanopro...

journal_title：Cutaneous and ocular toxicology

authors： Uematsu M,Mohamed YH,Onizuka N,Ueki R,Inoue D,Fujikawa A,Sasaki H,Kitaoka T

更新日期：2016-01-01 00:00:00

abstract：:A 56-year-old white woman developed a distinctive skin eruption over her mammary, lumbosacral, and pubic areas 2 weeks after the start of esomeprazole therapy for dyspeptic symptoms. Skin biopsy disclosed a spongiotic dermatitis with predominantly lymphocytic dermal infiltrate. Treatment with a tapering dose of cortic...

journal_title：Cutaneous and ocular toxicology

authors： Morais P,Baudrier T,Mota A,Cunha AP,Cadinha S,Barros AM,Azevedo F

更新日期：2010-09-01 00:00:00

abstract：OBJECTIVE:This report, the second in a series of five, directly compares the efficacy of Reactive Skin Decontamination Lotion (RSDL), the M291 Skin Decontamination Kit (SDK), 0.5% bleach (sodium or calcium hypochlorite solution), 1% soapy water, and Skin Exposure Reduction Paste Against Chemical Warfare Agents (SERPACW...

journal_title：Cutaneous and ocular toxicology

authors： Braue EH Jr,Smith KH,Doxzon BF,Lumpkin HL,Clarkson ED

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:There is increasing interest in minimally invasive skin sampling techniques to assay markers of molecular biology and biochemical processes. OBJECTIVE:This overview examines methodology strengths and limitations, and exciting developments pending in the scientific community. MATERIALS AND METHODS:Publicati...

journal_title：Cutaneous and ocular toxicology

authors： Wang CY,Maibach HI

更新日期：2011-03-01 00:00:00