Human skin buffering capacity against a reference base sodium hydroxide: in vitro model.

abstract：:Purpose: We have previously reported that skin barrier function is disrupted in mice with colonic tumours induced by azoxymethane (AOM) and dextran sodium sulphate (DSS). We postulated that the impaired skin barrier function was associated with reactive oxygen species derived from gp91phox. In this study, we investiga...

journal_title：Cutaneous and ocular toxicology

authors： Yokoyama S,Hiramoto K,Yamate Y

更新日期：2019-12-01 00:00:00

abstract：:A 63-year-old female with history of a resected frontal lobe meningioma presented with bilaterally decreased vision after a bite from a brown recluse spider. The exam was significant for a left relative afferent pupillary defect, bilateral optic nerve pallor, decreased foveal sensitivity in the left eye and new bilate...

journal_title：Cutaneous and ocular toxicology

authors： Mantopoulos D,Hendershot AJ,Cebulla CM,Hirsh DK

更新日期：2016-01-01 00:00:00

abstract：:The purpose of the present study was to measure and compare permeability coefficients (k(p)) and lag times (tau) in human skin and hairless guinea pig (HGP) skin. Paired experiments employed heat-separated epidermal membranes from human and HGP sources mounted on static in vitro diffusion cells. Infinite-dose, saturat...

journal_title：Cutaneous and ocular toxicology

authors： Frasch HF,Barbero AM

更新日期：2009-01-01 00:00:00

abstract：:Pustular irritant contact dermatitis is rare and unusual clinic form of contact dermatitis. Dexpanthenol is the stable alcoholic analogue of pantothenic acid. It is widely used in cosmetics and topical medical products for several purposes. We present the case of 8-year-old girl with pustules over erythematous and ecz...

journal_title：Cutaneous and ocular toxicology

authors： Gulec AI,Albayrak H,Uslu E,Başkan E,Aliagaoglu C

更新日期：2015-03-01 00:00:00

abstract：PURPOSE:Hazelnut and birch pollen are known to destroy tear film components and attack ocular surface cells. We investigated further pollen species from different plant families, whether they show similar effects on human tear fluid and an epithelial cell line in vitro, to provide a broad basis for further research on ...

journal_title：Cutaneous and ocular toxicology

authors： Rabensteiner DF,Rabensteiner J,Horwath-Winter J,Lang-Loidolt D,Wedrich A,Heidinger A,Schwantzer G,Schmut O

更新日期：2019-03-01 00:00:00

abstract：PURPOSE:To evaluate the treatment of autologous serum eye drops (ASED) on dry eyes in patients with graft-versus-host disease (GVHD). METHODS:A retrospective chart review of 35 patients with a history of ocular GVHD following hematopoietic stem cell transplantation that used ASED to alleviate dry eye symptoms was perf...

journal_title：Cutaneous and ocular toxicology

authors： Azari AA,Karadag R,Kanavi MR,Nehls S,Barney N,Kim K,Longo W,Hematti P,Juckett M

更新日期：2017-06-01 00:00:00

abstract：:A 56-year-old white woman developed a distinctive skin eruption over her mammary, lumbosacral, and pubic areas 2 weeks after the start of esomeprazole therapy for dyspeptic symptoms. Skin biopsy disclosed a spongiotic dermatitis with predominantly lymphocytic dermal infiltrate. Treatment with a tapering dose of cortic...

journal_title：Cutaneous and ocular toxicology

authors： Morais P,Baudrier T,Mota A,Cunha AP,Cadinha S,Barros AM,Azevedo F

更新日期：2010-09-01 00:00:00

abstract：PURPOSE:To evaluate the effects of the topical application of nondiluted autologous serum on epithelial healing as an adjuvant therapy in rabbit corneal alkali wounds. METHODS:Central corneal alkali wounds were produced on the right eye of 16 rabbits, by a 60-second application of a 6-mm round filter paper soaked in 1...

journal_title：Cutaneous and ocular toxicology

authors： Salman IA,Gündoğdu C

更新日期：2010-06-01 00:00:00

abstract：:Dicyclohexylcarbodiimide (DCC) and Diisopropylcarbodiimide (DIC) are two representative chemicals in the carbodiimide class of chemicals used in industry as stabilizing agents. There is a potential of dermal exposure to these agents in chemical, pharmaceutical and recombinant DNA industries. The National Toxicology Pr...

journal_title：Cutaneous and ocular toxicology

authors： Surh I,Behl M,Elmore SA,Chhabra RS

更新日期：2012-09-01 00:00:00

abstract：INTRODUCTION:Sulfur mustard (SM) has been used as a dangerous chemical warfare agent since the early 20th century. Although many descriptive studies about SM-induced ocular injuries are present in the medical literature, few of them have been conducted over a large group with serious ocular involvement. MATERIALS AND ...

journal_title：Cutaneous and ocular toxicology

authors： Ghasemi H,Ghazanfari T,Ghassemi-Broumand M,Javadi MA,Babaei M,Soroush MR,Yaraee R,Faghihzadeh S,Poorfarzam S,Owlia P,Naghizadeh MM,Etezad-Razavi M,Jadidi K,Naderi M,Hassan ZM

更新日期：2009-01-01 00:00:00

abstract：:We report a case of ophthalmic antibiotic ointment in the anterior chamber following uneventful phacoemulsification surgery. Antibiotic ointment was observed in the superior angle beneath the clear corneal wound one month later. The patient remained asymptomatic for 26 months after surgery until mild iritis developed....

journal_title：Cutaneous and ocular toxicology

authors： Ugurbas SC,Akova YA

更新日期：2010-09-01 00:00:00

abstract：PURPOSE:Welding workers' ophthalmic problems resulting from their professions are frequently observed in ophthalmic emergencies and can cause severe visual impairment. We aimed to investigate the use of topical anesthetic and non-medical alternatives of this population regarding ophthalmic problems in this study. MATE...

journal_title：Cutaneous and ocular toxicology

authors： Aslan L,Sucakli MH,Bozkurt S,Aslankurt M,Aksoy A,Celik M

更新日期：2014-06-01 00:00:00

abstract：:Rapid decontamination is vital to alleviate adverse health effects following dermal exposure to hazardous materials. There is an abundance of materials and products which can be utilised to remove hazardous materials from the skin. In this study, a total of 15 products were evaluated, 10 of which were commercial or mi...

journal_title：Cutaneous and ocular toxicology

authors： Matar H,Guerreiro A,Piletsky SA,Price SC,Chilcott RP

更新日期：2016-01-01 00:00:00

abstract：PURPOSE:The purpose of this study was to compare the neovascularization inhibiting the effect of topical bevacizumab and sorafenib and to determine the effective dose of sorafenib. MATERIAL AND METHODS:Forty-two healthy Wistar albino rats were randomly divided into six groups. The right corneas of all rats except grou...

journal_title：Cutaneous and ocular toxicology

authors： Yildirim H,Aydemir O,Balbaba M,Özercan İH,İlhan N

更新日期：2020-09-01 00:00:00

abstract：PURPOSE:The aim of this study was to evaluate and compare the toxicity of six different types of titanium dioxide (TiO2) nanoparticles (NP) on human epidermal keratinocytes (HEK). MATERIALS AND METHODS:Six TiO2 NP (A (10 nm), A*(32 nm), B (27.5 nm), C (200 nm), C*(30-40 nm), and D*(200-400 nm)) were suspended in water...

journal_title：Cutaneous and ocular toxicology

authors： Zhang LW,Monteiro-Riviere NA

更新日期：2019-03-01 00:00:00

abstract：:Purpose: Pityriasis rosea (PR) is a common, self-limiting, inflammatory skin disease with an acute onset. The etiology of PR is not yet clearly known but the defect in the oxidation system involved in many papulosquamous skin diseases may play a role. Thiol/disulfide homeostasis is a new marker of oxidative stress and...

journal_title：Cutaneous and ocular toxicology

authors： Yüksel M,Ülfer G

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:The present cross-sectional study has the purpose to investigate the impact of aromatase inhibitors (AIs) on retinal nerve fiber layer (RNFL) thickness, optic nerve and macular function in patients using AIs for breast cancer treatment. METHODS:Participants in our study were 41 hormone-receptor-positive ear...

journal_title：Cutaneous and ocular toxicology

authors： Moschos MM,Chatziralli IP,Sergentanis T,Zagouri F,Chrysikos D,Ladas I,Zografos G

更新日期：2016-03-01 00:00:00

abstract：PURPOSE:Warfarin (WF) is an anticoagulant which also affects physiological processes other than hemostasis. Our previous investigations showed the effect of WF which gained access to the organism via skin on resting peripheral blood granulocytes. Based on these data, the aim of the present study was to examine whether ...

journal_title：Cutaneous and ocular toxicology

authors： Mirkov I,Popov Aleksandrov A,Demenesku J,Ninkov M,Mileusnic D,Kataranovski D,Kataranovski M

更新日期：2017-09-01 00:00:00

abstract：:Skin patch testing of menses and venous blood on the vulva (labia majora) and the upper arm was performed to assess the potential contribution of these biological fluids to vulvar irritation during menstruation. After 24 and 48 hours of occlusive exposure, the skin of the labia majora was relatively unaffected by thes...

journal_title：Cutaneous and ocular toxicology

authors： Farage M,Warren R,Wang-Weigand S

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:The exact immunopathogenesis of contact hypersensitivity (CH) to mercury remains unclear. OBJECTIVE:The aim of the present study was to assess the role of CD4+ T cells in mercury-induced CH in mice. METHODS:Splenic CD4+ T cells obtained from nonsensitized and mercury-sensitized Balb/c mice were adoptively ...

journal_title：Cutaneous and ocular toxicology

authors： Sumiwi YA,Soesatyo MH,Sosroseno W

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:Vancomycin is the gold standard in combination therapy for severe and resistant gram-positive keratitis and in particular for Methicillin-resistant Staphylococcus aureus (MRSA) infections. The aim of this study was to report the ocular surface toxicity and scoring in patients whose treatment shifted to topic...

journal_title：Cutaneous and ocular toxicology

authors： Akova Budak B,Baykara M,Kıvanç SA,Yilmaz H,Cicek S

更新日期：2016-01-01 00:00:00

abstract：:The skin is a major exposure route for many potentially toxic chemicals. It is, therefore, important to be able to predict the permeability of compounds through skin under a variety of conditions. Available skin permeability databases are often limited in scope and not conducive to developing effective models. This sp...

journal_title：Cutaneous and ocular toxicology

authors： Keshwani DR,Jones DD,Brand RM

更新日期：2005-01-01 00:00:00

abstract：CONTEXT:Nicorandil is an antianginal drug used for 20 years in Japan and introduced in France in 1994. Since 1997, side effects such as mucocutaneous ulcerations have regularly been reported. OBJECTIVE:To describe the first case of a patient with a spontaneous corneal perforation associated with mucocutaneous ulcerati...

journal_title：Cutaneous and ocular toxicology

authors： Campolmi N,Guy C,Cinotti E,Forest F,Gain P,Philippe-Zech C,Gauthier AS,Thuret G

更新日期：2014-06-01 00:00:00

abstract：PURPOSE:Evaluation of retinal and choroidal changes after energy drink consumption by optical coherence tomography and optical coherence tomography angiography. METHODS AND MATERIAL:Forty-two healthy volunteers with neither systemic nor ocular diseases were enrolled in the study. The energy drink (250 mL Red Bull ener...

journal_title：Cutaneous and ocular toxicology

authors： Doğan M,Sabaner MC,Akar AT,Şenel M,Kaşikçi İ,Günal EŞ,Özbay AE,Şarman T,Gobeka HH,Cam Ö

更新日期：2020-12-01 00:00:00

abstract：:In the EU, Methylisothiazolinone (MI) was approved as a preservative in cosmetics and household products in 2005. Since then, several cases of MI contact allergy have been reported. We studied the prevalence of MI sensitization in patients allergic to Methylchloroisothiazolinone/Methylisothiazolinone (MCI/MI). From a ...

journal_title：Cutaneous and ocular toxicology

authors： Macias VC,Fernandes S,Amaro C,Santos R,Cardoso J

更新日期：2013-06-01 00:00:00

abstract：:Ciliary body is responsible for humour aqueous production in posterior chamber. Valproic acid (VPA) has been widely used for the treatment of epilepsy and other neuropsychiatric diseases such as bipolar disease and major depression. Oxcarbazepine (OXC) is a new anti-epileptic agent that has been used recently for chil...

journal_title：Cutaneous and ocular toxicology

authors： Göktaş G,Aktaş Z,Erdoğan D,Seymen CM,Karaca EE,Cansu A,Serdaroğlu A,Kaplanoğlu GT

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND/OBJECTIVE:Acne vulgaris is one of the most common diseases of the youth. Systemic isotretinoin is the only drug which acts on all of the etiopathogenic mechanisms of acne. Isotretinoin has some well-known side effects. Besides these, there is a suspicion whether it causes infertility or not. In this study, w...

journal_title：Cutaneous and ocular toxicology

authors： Çinar L,Kartal D,Ergin C,Aksoy H,Karadag MA,Aydin T,Cinar E,Borlu M

更新日期：2016-12-01 00:00:00

abstract：:Lichenoid drug eruption (LDE) is a common cutaneous side effect of drugs including antimalarials, antihypertensives, nonsteroids, anti-inflammatory drugs and diuretics. The physiopathologic relationship between colchicine treatment and LDE is unclear. There is very little documentation of LDE induced by colchicine in ...

journal_title：Cutaneous and ocular toxicology

authors： An I,Demir V,Akdeniz S

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:Fixed drug eruption (FDE) is a special variant of drug reaction seen on skin or mucous membrane, and typically recurs at the same location. Ornidazole-induced FDE cases have been reported extremely rare. CASE:The 48-year-old female patient was diagnosed for ornidazole-induced fixed drug reaction on the sole...

journal_title：Cutaneous and ocular toxicology

authors： Emre S,Ahsen H,Aktaş A

更新日期：2017-09-01 00:00:00

abstract：PURPOSE:To assess the long-term intraocular pressure (IOP) changes after the intravitreal injection of bevacizumab (Avastin; Genentech, Inc., South San Francisco, CA) for treatment of age-related macular degeneration (AMD) and diabetic macular edema (DME) patients and evaluate the correlation factors. MATERIAL AND MET...

journal_title：Cutaneous and ocular toxicology

authors： Baek SU,Park IW,Suh W

更新日期：2016-12-01 00:00:00