Early amniotic membrane transplantation for toxic keratopathy secondary to topical proparacaine abuse: a report of seven cases.

abstract：:Purpose: We have previously reported that skin barrier function is disrupted in mice with colonic tumours induced by azoxymethane (AOM) and dextran sodium sulphate (DSS). We postulated that the impaired skin barrier function was associated with reactive oxygen species derived from gp91phox. In this study, we investiga...

journal_title：Cutaneous and ocular toxicology

authors： Yokoyama S,Hiramoto K,Yamate Y

更新日期：2019-12-01 00:00:00

abstract：:The purpose of the present study was to measure and compare permeability coefficients (k(p)) and lag times (tau) in human skin and hairless guinea pig (HGP) skin. Paired experiments employed heat-separated epidermal membranes from human and HGP sources mounted on static in vitro diffusion cells. Infinite-dose, saturat...

journal_title：Cutaneous and ocular toxicology

authors： Frasch HF,Barbero AM

更新日期：2009-01-01 00:00:00

abstract：:Attempts to improve formulation of topical products are a continuing process and the development of micro- and nanovesicular systems as well as polymeric microparticles has led to marketing of topical drugs and cosmetics using these technologies. Encapsulation of some well-known contact allergens in ethanolic liposome...

journal_title：Cutaneous and ocular toxicology

authors： Madsen JT,Vogel S,Johansen JD,Andersen KE

更新日期：2011-06-01 00:00:00

abstract：PURPOSE:The aim of this study was to determine the effects of single-dose intravitreal bevacizumab on the levels of vascular endothelial growth factor (VEGF) in serum and distant organs. METHODS:Adult New Zealand albino rabbits (n = 40) were divided into experimental and control groups. Experimental rabbits received a...

journal_title：Cutaneous and ocular toxicology

authors： Dınc E,Yıldırım O,Necat Yılmaz S,Canacankatan N,Ayaz L,Ozcan T,Temel GO

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:In our study, we aimed to show the effects of smoking on choroidal thickness and ocular pulse amplitude. It is known that the anatomy and physiologic functions of the choroid is important in ocular diseases like glaucoma and age-related macular degeneration. Choroidal thickness is measured by the spectral do...

journal_title：Cutaneous and ocular toxicology

authors： Dervişoğulları MS,Totan Y,Tenlik A,Yuce A

更新日期：2015-01-01 00:00:00

abstract：:Psoriasis is a common skin disorder that needs a long-term management, not only because, of its prevalence but also because of the profound impact it can have on patients quality of life. Drugs may result in exacerbation of a preexisting psoriasis, in induction of psoriatic lesions on clinically uninvolved skin in pat...

journal_title：Cutaneous and ocular toxicology

authors： Dika E,Varotti C,Bardazzi F,Maibach HI

更新日期：2006-01-01 00:00:00

abstract：PURPOSE:To evaluate the effect of anti-tubercular treatment on retinal nerve fiber layer (RNFL) thickness and the efficiency of optic coherence tomography (OCT) on early diagnosis of optic neuropathy. METHODS:Twenty patients diagnosed with either pulmonary or extra-pulmonary tuberculosis which were treated with anti-t...

journal_title：Cutaneous and ocular toxicology

authors： Gümüş A,Öner V

更新日期：2015-01-01 00:00:00

abstract：:Dermal absorption of some chemicals and drugs can cause systemic toxicity. We evaluated several case reports from the past decade, which discuss the dermal absorption of a specific chemical and potential local and systemic effects. We focused on herbicide and pesticide exposure along with exposure to cutaneous medicat...

journal_title：Cutaneous and ocular toxicology

authors： Alikhan FS,Maibach H

更新日期：2011-09-01 00:00:00

abstract：PURPOSE:To assess the long-term intraocular pressure (IOP) changes after the intravitreal injection of bevacizumab (Avastin; Genentech, Inc., South San Francisco, CA) for treatment of age-related macular degeneration (AMD) and diabetic macular edema (DME) patients and evaluate the correlation factors. MATERIAL AND MET...

journal_title：Cutaneous and ocular toxicology

authors： Baek SU,Park IW,Suh W

更新日期：2016-12-01 00:00:00

abstract：:Context Incontinence-associated dermatitis (IAD) is a type of moisture-associated dermatitis caused by repeated skin exposure to urine or stool. A product that could mitigate such symptoms would have a significant impact on cost of care and patients' quality of life. Objective This study compared the clinical efficacy...

journal_title：Cutaneous and ocular toxicology

authors： Matar H,Larner J,Viegas V,Kansagra S,Atkinson KL,Shetage S,Skamarauskas JT,Theivendran B,Goldman VS,Chilcott RP

更新日期：2017-09-01 00:00:00

abstract：:Ciliary body is responsible for humour aqueous production in posterior chamber. Valproic acid (VPA) has been widely used for the treatment of epilepsy and other neuropsychiatric diseases such as bipolar disease and major depression. Oxcarbazepine (OXC) is a new anti-epileptic agent that has been used recently for chil...

journal_title：Cutaneous and ocular toxicology

authors： Göktaş G,Aktaş Z,Erdoğan D,Seymen CM,Karaca EE,Cansu A,Serdaroğlu A,Kaplanoğlu GT

更新日期：2015-01-01 00:00:00

abstract：PURPOSE:The purpose of this study was to compare the neovascularization inhibiting the effect of topical bevacizumab and sorafenib and to determine the effective dose of sorafenib. MATERIAL AND METHODS:Forty-two healthy Wistar albino rats were randomly divided into six groups. The right corneas of all rats except grou...

journal_title：Cutaneous and ocular toxicology

authors： Yildirim H,Aydemir O,Balbaba M,Özercan İH,İlhan N

更新日期：2020-09-01 00:00:00

abstract：CONTEXT:Assessing the hazards of accidental exposure to toxic industrial chemical (TIC) vapors and evaluating therapeutic compounds or treatment regimens require the development of appropriate animal models. OBJECTIVE:The objective of this project was to develop an exposure system for delivering controlled vapor conce...

journal_title：Cutaneous and ocular toxicology

authors： Snider TH,Perry MR,Richter WR,Plahovinsak JL,Rogers J,Reid FM,Graham JS

更新日期：2014-06-01 00:00:00

abstract：:Patch testing is an important tool in the diagnosis of allergic contact dermatitis. Although this technique can be accurate, occasionally the results may be inconclusive. A previously positive result to an allergen may become negative upon repeat testing, and this may complicate the process of achieving a definitive d...

journal_title：Cutaneous and ocular toxicology

authors： Zapolanski T,Maibach HI

更新日期：2008-01-01 00:00:00

abstract：PURPOSE:The aim of this study was to examine the effects of long-term use of hydroxychloroquine (HQ) on the pachymetric, aberrometric, and densitometric values of the cornea and corneal endothelium in lupus patients. METHOD:Twenty-two eyes (study group) of 22 patients using HQ for treatment of lupus and 25 eyes (contr...

journal_title：Cutaneous and ocular toxicology

authors： Çağlayan M,Akyol L,Balcı MA,Öncül H,Alakuş MF,Dağ U

更新日期：2020-12-23 00:00:00

abstract：:A snakebite is a serious and important problem in tropical and subtropical cities. A vast majority of snakebites are nonvenomous. However, venomous snakebites may cause local tissue destruction, neuroparalysis, systemic hemorrhage, generalized myotoxicity, and acute renal failure. A 10-year-old boy was brought to the ...

journal_title：Cutaneous and ocular toxicology

authors： Ozkol HU,Karadag AS,Bilgili SG,Calka O

更新日期：2011-12-01 00:00:00

abstract：:The terrifying dog in the Hound of the Baskervilles is described as having 'blazing eyes' and a 'luminous muzzle', appearances attributed by Watson and Holmes to the application of phosphorus. Review of the toxicity and flammability of white phosphorus make this improbable. It is suggested that Conan Doyle's descripti...

journal_title：Cutaneous and ocular toxicology

authors： Dayan AD

更新日期：2008-01-01 00:00:00

abstract：:A 56-year-old white woman developed a distinctive skin eruption over her mammary, lumbosacral, and pubic areas 2 weeks after the start of esomeprazole therapy for dyspeptic symptoms. Skin biopsy disclosed a spongiotic dermatitis with predominantly lymphocytic dermal infiltrate. Treatment with a tapering dose of cortic...

journal_title：Cutaneous and ocular toxicology

authors： Morais P,Baudrier T,Mota A,Cunha AP,Cadinha S,Barros AM,Azevedo F

更新日期：2010-09-01 00:00:00

abstract：:Background: Papulopustular rash is the most common cutaneous adverse effect during targeted tumour therapy particularly with epidermal growth factor receptor inhibitors (EGFRIs). Objective: To evaluate the adverse skin reactions, mainly papulopustular rash, caused by targeted tumour therapy. Materials and methods: We ...

journal_title：Cutaneous and ocular toxicology

authors： Yalici-Armagan B,Ayanoglu BT,Demirdag HG

更新日期：2019-09-01 00:00:00

abstract：OBJECTIVE:The aim of this study is to compare the effect of prostaglandin analogues preserved with either 0.015% or 0.001% benzalkoium chloride (BAK); or 0.001% polyquad (PQ) on the ocular surface of rabbit eyes. METHODS:Forty white rabbits were randomized to receive four-times daily instillation of either 0.0015% taf...

journal_title：Cutaneous and ocular toxicology

authors： Lee HJ,Jun RM,Cho MS,Choi KR

更新日期：2015-01-01 00:00:00

abstract：:The bullous hemorrhagic dermatosis induced by enoxaparin is a rare adverse reaction, which may be under-reported given its favorable evolution. We report a 71-year-old man who developed hemorrhagic bullae at sites distant from subcutaneous enoxaparin injections. It is important that clinicians be aware of the differen...

journal_title：Cutaneous and ocular toxicology

authors： Gouveia AI,Lopes L,Soares-Almeida L,Filipe P

更新日期：2016-01-01 00:00:00

abstract：PURPOSE:Delayed keratitis is the most dangerous ocular complication of sulfur mustard (SM) exposure. This study aimed to evaluate the role of tear and serum levels of interleukin-8 (IL-8) in SM exposed subjects. DESIGN AND METHODS:In this historical cohort study, the experimental group included 370 participants who ha...

journal_title：Cutaneous and ocular toxicology

authors： Ghasemi H,Ghazanfari T,Yaraee R,Pourfarzam S,Soroush MR,Faghihzadeh S,Babaei M,Naghizadeh MM,Mohammad Hassan Z

更新日期：2012-06-01 00:00:00

abstract：PURPOSE:To evaluate antioxidant effects of active vitamin D (calcitriol) against high-dose radioiodine (RAI) therapy-associated damage of lacrimal gland. MATERIALS AND METHODS:Wistar albino rats were used and divided into three groups randomly (n = 12/group). The first group was appointed as the negative control group...

journal_title：Cutaneous and ocular toxicology

authors： Eksioglu U,Atilgan HI,Yakin M,Yazihan N,Altiparmak UE,Yumusak N,Korkmaz M,Demir A,Ornek F,Aribal Ayral P,Koca G

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:Systemic isotretinoin (13-cis-retinoic acid) is effective in the treatment of acne vulgaris. The most common side effects are mucocutaneous ones. Hematuria seen secondary to isotretinoin treatment is thought to be due to mucosal dryness in the urinary system. This study aims to determine the frequency of hem...

journal_title：Cutaneous and ocular toxicology

authors： Yesilkaya B,Alli N,Artuz RF,Ulu E,Kartal D,Cinar SL

更新日期：2017-03-01 00:00:00

abstract：:Chemical sensitization is a serious condition caused by small reactive molecules and is characterized by a delayed type hypersensitivity known as allergic contact dermatitis (ACD). Contact with these molecules via dermal exposure represent a significant concern for chemical manufacturers. Recent legislation in the EU ...

journal_title：Cutaneous and ocular toxicology

authors： McKim JM Jr,Keller DJ 3rd,Gorski JR

更新日期：2012-12-01 00:00:00

abstract：:Skin patch testing of menses and venous blood on the vulva (labia majora) and the upper arm was performed to assess the potential contribution of these biological fluids to vulvar irritation during menstruation. After 24 and 48 hours of occlusive exposure, the skin of the labia majora was relatively unaffected by thes...

journal_title：Cutaneous and ocular toxicology

authors： Farage M,Warren R,Wang-Weigand S

更新日期：2005-01-01 00:00:00

abstract：:The skin is a major exposure route for many potentially toxic chemicals. It is, therefore, important to be able to predict the permeability of compounds through skin under a variety of conditions. Available skin permeability databases are often limited in scope and not conducive to developing effective models. This sp...

journal_title：Cutaneous and ocular toxicology

authors： Keshwani DR,Jones DD,Brand RM

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Fixed drug eruption (FDE) is a special variant of drug reaction seen on skin or mucous membrane, and typically recurs at the same location. Ornidazole-induced FDE cases have been reported extremely rare. CASE:The 48-year-old female patient was diagnosed for ornidazole-induced fixed drug reaction on the sole...

journal_title：Cutaneous and ocular toxicology

authors： Emre S,Ahsen H,Aktaş A

更新日期：2017-09-01 00:00:00

abstract：:We report a case of ophthalmic antibiotic ointment in the anterior chamber following uneventful phacoemulsification surgery. Antibiotic ointment was observed in the superior angle beneath the clear corneal wound one month later. The patient remained asymptomatic for 26 months after surgery until mild iritis developed....

journal_title：Cutaneous and ocular toxicology

authors： Ugurbas SC,Akova YA

更新日期：2010-09-01 00:00:00

abstract：PURPOSES:To study the occurrence of ocular surface diseases on coal miners working under wells and to investigate the relation between xerophthalmia occurrence and coal dust contiguity. METHODS:To observe the influence of coal dust to ocular surface by using Schirmer to detect lacrimal gland secreting function, and br...

journal_title：Cutaneous and ocular toxicology

authors： Sun Z,Hong J,Yang D,Liu G

更新日期：2007-01-01 00:00:00