Abstract：
INTRODUCTION:Osteoporotic vertebral fractures are associated with significant morbidity, excess mortality as well as health and social service expenditure. Additionally, women with a prevalent osteoporotic vertebral fracture have a high risk of experiencing a further one within one year. It is therefore important for the physician to use a diagnostic and therapeutic algorithm for early detection and effective treatment of vertebral fractures. AIMS:The aim of this position statement is to provide and critically appraise evidence on the management of women with a vertebral osteoporotic fracture. MATERIALS AND METHODS:Literature review and consensus of expert opinion. RESULTS AND CONCLUSIONS:The management of women with osteoporotic vertebral fractures includes measures to reduce pain providing early mobility, to support the affected spine ensuring fracture healing, as well as starting treatment for osteoporosis itself. Any other underlying pathology should be sought and treated. Early detection and treatment is essential as there is an increased risk of further fractures in patients with vertebral fractures. Treatment will depend on the underlying causes of bone loss, efficacy in any particular situation, cost and patient preference.
journal_name
Maturitasjournal_title
Maturitasauthors
Triantafyllopoulos IK,Lambropoulou-Adamidou K,Nacopoulos CC,Papaioannou NA,Ceausu I,Depypere H,Erel CT,Pérez-López FR,Schenck-Gustafsson K,van der Schouw YT,Simoncini T,Tremollieres F,Rees M,Lambrinoudaki I,European Menopausedoi
10.1016/j.maturitas.2014.03.002subject
Has Abstractpub_date
2014-06-01 00:00:00pages
131-7issue
2eissn
0378-5122issn
1873-4111pii
S0378-5122(14)00067-Xjournal_volume
78pub_type
杂志文章,实务指引,评审相关文献
MATURITAS文献大全abstract：OBJECTIVES:To review the available information on the action of hormones on the mechanisms involved in thrombotic risk. RESULTS AND CONCLUSIONS:Thrombosis plays a crucial role in the genesis and progression of both coronary heart disease (CHD) and venous thromboembolic disease (VTED), the two main forms of cardiovascu...
journal_title：Maturitas
pub_type： 杂志文章,评审
doi：10.1016/s0378-5122(01)00270-5
更新日期：2001-10-31 00:00:00
abstract：:The extension of life expectancy is a global phenomenon. The growth in the ageing population has created a new health scenario in which there is a higher prevalence of frailty and multimorbidity. The attention received by both conditions derives from their strong association with disability, hospitalization, and death...
journal_title：Maturitas
pub_type： 杂志文章,评审
doi：10.1016/j.maturitas.2016.10.008
更新日期：2017-01-01 00:00:00
abstract：BACKGROUND:With the significant improvement of the cure rate and survival rate of cancer patients, the survivors face quality-of-life problems, such as a significant decline in reproductive system development, ovarian reserves and function, and even fertility loss and early menopause. These problems are often highly as...
journal_title：Maturitas
pub_type： 杂志文章
doi：10.1016/j.maturitas.2020.04.010
更新日期：2020-07-01 00:00:00
abstract：OBJECTIVE:New regimens and routes of administration of hormonal replacement therapy (HRT) in climateric women are becoming available. Since there is no information on the neuroendocrine effects of sequential combined treatment with 17 beta-estradiol and a progestin, the present study evaluated the neuroendocrine, clini...
journal_title：Maturitas
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0378-5122(97)00073-x
更新日期：1997-12-15 00:00:00
abstract：:Using the constant infusion technique we have measured the metabolic clearance rates (MCR) for delta 4-androstenedione (A), testosterone (T), oestrone (E1) and oestradiol (E2) in a large group of post-menopausal women. Their mean +/- SE age was 64.5 +/- 1.6 yr, their ages ranged from 46-90 yr. When the MCRs for each s...
journal_title：Maturitas
pub_type： 杂志文章
doi：10.1016/0378-5122(80)90030-4
更新日期：1980-12-01 00:00:00
abstract：:The aim of this trial was to study the vaginal absorption of oestriol and to investigate whether morning rather than evening oestriol administration would produce different plasma oestriol patterns. The influence of food intake on plasma oestriol levels was also investigated. Nine post-menopausal women were given 0.5 ...
journal_title：Maturitas
pub_type： 杂志文章
doi：10.1016/0378-5122(86)90031-9
更新日期：1986-10-01 00:00:00
abstract：:In a population-based prospective study it was shown that weight, height, overweight, total body size, age at first birth, parity and age at menopause are risk factors for the development of endometrial cancer. The finding that the patients had had a higher oestrogen excretion level than the controls some time before ...
journal_title：Maturitas
pub_type： 杂志文章
doi：10.1016/0378-5122(85)90036-2
更新日期：1985-05-01 00:00:00
abstract：:The change in lumbar vertebral bone mineral density (BMD) during a 2-year study period was examined in 167 healthy middle-aged and elderly Japanese women with reference to age, menopausal status and bone turnover markers at baseline. The perimenopausal and postmenopausal groups of the subjects showed a significant los...
journal_title：Maturitas
pub_type： 杂志文章
doi：10.1016/0378-5122(96)01042-0
更新日期：1996-08-01 00:00:00
abstract：OBJECTIVES:Bone mineral density (BMD) and development of osteoporosis are partly determined by genetic factors. The associations between one of suggested candidate, apolipoprotein E (apo E) genotype to bone mineral density (BMD) and bone biochemical markers was studied in 464 subjects recruited from a population-based ...
journal_title：Maturitas
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0378-5122(99)00084-5
更新日期：2000-01-15 00:00:00
abstract：BACKGROUND/AIM:The aim of this study was to compare the role of quantitative ultrasonography (QUS) and dual energy X-ray absorptiometry (DEXA) in the assessment of osteoporosis. METHODS:From June 1999 to November 2001, 596 women who have not been diagnosed osteoporosis and without previous history of pathologic fractu...
journal_title：Maturitas
pub_type： 杂志文章
doi：10.1016/s0378-5122(02)00036-1
更新日期：2002-06-25 00:00:00
abstract：OBJECTIVE:The role of endogenous testosterone in the pathogenesis of type 2 diabetes mellitus remains vague. We investigated whether associations between endogenous testosterone and diabetes prevalence in men could be partially explained by modifiable risk factors. STUDY DESIGN:A random population-based cross-sectiona...
journal_title：Maturitas
pub_type： 杂志文章
doi：10.1016/j.maturitas.2010.12.007
更新日期：2011-03-01 00:00:00
abstract：:The synthetic progestins used so far for contraception and menopausal hormone therapy are derived either from testosterone (19-nortestosterone derivatives) or from progesterone (17-OH progesterone derivatives and 19-norprogesterone derivatives). Among the 19-nortestosterone derivatives, the estrane group include noret...
journal_title：Maturitas
pub_type： 杂志文章,评审
doi：10.1016/j.maturitas.2004.01.001
更新日期：2004-04-15 00:00:00
abstract：OBJECTIVES:Since the ageing population demands a response to ensure older people remain healthy and active, we studied the dynamics of a recently proposed healthy ageing phenotype. We drew the phenotype's trajectories and tested whether their levels and rates of change are influenced by health behaviours, comorbidities...
journal_title：Maturitas
pub_type： 杂志文章
doi：10.1016/j.maturitas.2016.03.002
更新日期：2016-06-01 00:00:00
abstract：:Burning mouth syndrome associated to vulvodynia (Vulvostomatodynia) is a rare condition and is often difficult to diagnose and treat. Tongue, lips, vestibule and others mucosal sites may be affected by a tiresome burning sensation, especially in menopausal and postmenopausal women. Patients seldom report genital sympt...
journal_title：Maturitas
pub_type： 杂志文章
doi：10.1016/j.maturitas.2007.05.003
更新日期：2007-09-20 00:00:00
abstract：:Although age is the most crucial predictor of a woman's reproductive capacity, it is assumed that there is still a risk of pregnancy in menopause transition, as occasional spontaneous ovulation is possible. Moreover, age alone is not sufficient to contraindicate the use of any contraceptive method, whether hormonal or...
journal_title：Maturitas
pub_type： 杂志文章,评审
doi：10.1016/j.maturitas.2014.02.017
更新日期：2014-05-01 00:00:00
abstract：OBJECTIVE:The use of hormone replacement therapy (HRT) declined strongly in many countries after publication of the WHI-study. The purpose of the present study was to investigate HRT usage patterns and motives for initiation, temporary discontinuation, and permanent discontinuation of HRT use among Norwegian women. ME...
journal_title：Maturitas
pub_type： 杂志文章
doi：10.1016/j.maturitas.2009.07.010
更新日期：2009-09-20 00:00:00
abstract：:Thirty-four post-menopausal women with climacteric complaints were given conjugated equine oestrogens (1.25 mg/day) for 21 days followed by 2 days without hormones and then 5 mg medroxyprogesteroneacetate daily for 5 days. The present trial was designed to study effects on vasomotor symptoms, bleeding patterns and end...
journal_title：Maturitas
pub_type： 杂志文章
doi：10.1016/0378-5122(84)90065-3
更新日期：1984-07-01 00:00:00
abstract：OBJECTIVE:Physical and psychological incapacity, including fear of falling is related to decreased satisfaction with life in osteoporosis (OP). The impact of a balance exercise program on improving the quality of life is not well established. We have, therefore, investigated the effect of 12-month Balance Training Prog...
journal_title：Maturitas
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.maturitas.2010.03.009
更新日期：2010-06-01 00:00:00
abstract：OBJECTIVE:Decision-making during menopause (especially surgical menopause) can be complex given the variability in risk-benefit perceptions of menopausal treatments. Decision aid tools (DATs) help women participate in decision-making about options. Our objective is to identify and evaluate the content and development o...
journal_title：Maturitas
pub_type： 杂志文章,评审
doi：10.1016/j.maturitas.2017.09.006
更新日期：2017-12-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:Cutaneous intrinsic ageing has been shown to be improved by hormone replacement therapy (HRT). Photoageing is, however, unresponsive to such treatment. The present double-blind study was undertaken to compare the beneficial effect of a 1-month topical treatment with 0.05% all-trans-retinoic ac...
journal_title：Maturitas
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/0378-5122(95)00983-3
更新日期：1996-04-01 00:00:00
abstract：:Health care focuses on controlling symptoms and managing risk factors to improve survival by avoiding future complications. Diagnoses describe a group of signs and symptoms, often implying specific aetiologies and underlying pathophysiological disease processes. The diagnosis provides a tool for the health professiona...
journal_title：Maturitas
pub_type： 杂志文章,评审
doi：10.1016/j.maturitas.2019.02.010
更新日期：2019-05-01 00:00:00
abstract：OBJECTIVE:To determine the changes in levels of urinary NTx at the end of the 6th month of oral and transdermal hormone replacement therapy (HRT) and the effects of additional alendronate therapy for osteoporotic women. METHOD:Of 66 postmenopausal women 23 were treated with oral estradiol+norethisterone acetate (E+P),...
journal_title：Maturitas
pub_type： 杂志文章
doi：10.1016/s0378-5122(02)00156-1
更新日期：2002-08-30 00:00:00
abstract：:Serum and urine electrolytes, and biochemical indices of bone metabolism and liver function were measured in 51 post-menopausal women treated with two hormone replacement therapy regimens for 24 wk. Twenty-six of the women were treated continuously with conjugated equine oestrogens (0.625 mg/day) and the remainder wer...
journal_title：Maturitas
pub_type： 杂志文章
doi：10.1016/0378-5122(88)90100-4
更新日期：1988-03-01 00:00:00
abstract：:In the past decade, the leading international cardiology societies have released statements that emphasize the importance of sex-specific reporting of the findings of clinical trials in cardiovascular research. To find out whether this has led to improvement, we compared sex-specific reporting of efficacy and safety o...
journal_title：Maturitas
pub_type： 杂志文章
doi：10.1016/j.maturitas.2020.09.007
更新日期：2021-02-01 00:00:00
abstract：:The management of medications in persons with frailty presents challenges. There is evidence of inappropriate prescribing and a lack of consensus among healthcare professionals on the judicious use of medications, particularly for patients with more severe frailty. This study reviews the evidence on the use of commonl...
journal_title：Maturitas
pub_type： 杂志文章,评审
doi：10.1016/j.maturitas.2019.04.212
更新日期：2019-08-01 00:00:00
abstract：OBJECTIVE:To determine the association between relationship distress and menopausal symptoms. STUDY DESIGN:A retrospective analysis was conducted of questionnaires completed by women 40-65 years of age seeking menopause or sexual health consultation between May, 2015 and May, 2017. MAIN OUTCOME MEASURES:Associations ...
journal_title：Maturitas
pub_type： 杂志文章
doi：10.1016/j.maturitas.2019.09.006
更新日期：2019-12-01 00:00:00
abstract：:The present study had two objectives: (1) to register the prevalence of a number of climacteric complaints in a Danish general population cohort and (2) retrospectively to test the validity of an association between climacteric complaints, menopausal development, occurrence of life events and social background. A post...
journal_title：Maturitas
pub_type： 杂志文章
doi：10.1016/0378-5122(93)90043-h
更新日期：1993-11-01 00:00:00
abstract：OBJECTIVE:To determine the percentage of endometrial hyperplasia positive for p53 expression in both spontaneously occurring cases or following the use of unopposed estradiol. METHODS:Fifty-four postmenopausal patients with endometrial hyperplasia diagnosed by endometrial biopsy and hysteroscopy were recruited to this...
journal_title：Maturitas
pub_type： 杂志文章
doi：10.1016/s0378-5122(02)00326-2
更新日期：2003-03-28 00:00:00
abstract：OBJECTIVES:Estrogen is often prescribed for symptoms and sequelae of ovarian estrogen loss after menopause. METHODS:To assess efficacy and acceptability of a new, highly soluble estrogen-calcium preparation, we formulated a water-soluble powdered combination of estrogen (0.625 mg estrone piperazine sulfate) and calciu...
journal_title：Maturitas
pub_type： 杂志文章
doi：10.1016/s0378-5122(00)00218-8
更新日期：2001-04-20 00:00:00
abstract：:The aim of this chronobiological study was to investigate temporal correlations in the circadian patterns of 6 hormones, namely somatotrophic hormone (STH), prolactin (PRL), cortisol (F), aldosterone (ALD), insulin (IRI) and C-peptide (CP), assayed in systemic blood serum drawn at 07:00, 10:00, 13:00, 16:00, 19:00 and...
journal_title：Maturitas
pub_type： 杂志文章
doi：10.1016/0378-5122(85)90024-6
更新日期：1985-07-01 00:00:00
