Reporting of sex-specific outcomes in trials of interventions for cardiovascular disease: Has there been progress?

abstract：OBJECTIVE:To determine the effects of oral sequential hormone replacement therapy (HRT) on lipid-profile in perimenopausal and early postmenopausal women. METHODS:We performed a single-center, randomized, placebo-controlled trial. The trial was double blind with respect to 17beta-estradiol/desogestrel (17beta-E-D) and...

journal_title：Maturitas

authors： Ossewaarde ME,Bots ML,Bak AA,Van Der Schouw YT,Witteman JC,Planellas J,Bennink HJ,Grobbee DE

更新日期：2001-09-28 00:00:00

abstract：OBJECTIVES:The aim of the present study was to evaluate the effects of low doses of hormone replacement therapy (HRT) in normal young postmenopausal women. METHODS:In an open trial healthy, non-obese postmenopausal women received for 2 years a low-dose continuous combined HRT (LD-HRT) containing 1mg estradiol+0.5 mg n...

journal_title：Maturitas

authors： Gambacciani M,Cappagli B,Ciaponi M,Pepe A,Vacca F,Genazzani AR

更新日期：2008-01-20 00:00:00

abstract：OBJECTIVES:Studies focusing on lifestyle and health factors and stress urinary incontinence (SUI) are scarce in Japan. The aim of this study is to examine the association of lifestyle and health factors in SUI. METHODS:Study subjects were retrieved from Japanese women participating in a health checkup program provided...

journal_title：Maturitas

authors： Masue T,Wada K,Nagata C,Deguchi T,Hayashi M,Takeda N,Yasuda K

更新日期：2010-07-01 00:00:00

abstract：:Sixteen post-menopausal women who had never previously received any hormonal treatment applied Oestrogel cream 1.5 mg/day percutaneously for 1 yr. Skin biopsies were taken from the abdomen and from the lateral aspect of the thigh at 0, 3, 6 and 12 mth, and the changes in skin collagen content were noted. The abdominal...

journal_title：Maturitas

authors： Brincat M,Versi E,O'Dowd T,Moniz CF,Magos A,Kabalan S,Studd JW

更新日期：1987-04-01 00:00:00

abstract：OBJECTIVE:The present study investigated bone turnover with exchange of hormone replacement therapy (HRT) by treatment with 1alpha-hydroxycholecalciferol in early postmenopausal women. METHODS:Subjects included a total of 75 postmenopausal women between 49 and 59 years of age who visited the Department of Obstetrics a...

journal_title：Maturitas

authors： Ushiroyama T,Ikeda A,Sakai M,Higashiyama T,Ueki M

更新日期：2003-06-30 00:00:00

abstract：OBJECTIVES:Frailty and cognitive impairment in late life increase the risk of mortality. Physical frailty is closely associated with cognitive impairment. The aim of the study was to examine the independent and interaction effects of frailty and cognitive impairment in predicting mortality. STUDY DESIGN:A nationally r...

journal_title：Maturitas

authors： Lee Y,Kim J,Chon D,Lee KE,Kim JH,Myeong S,Kim S

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVE:The objective of this study was to evaluate gynecologists' knowledge of the WHI study, and its repercussions on their attitudes and practice 3 years after publication. DESIGN:A self-administered, anonymous questionnaire containing 19 questions was sent to 6000 gynecologists, members of the São Paulo Society ...

journal_title：Maturitas

authors： Lazar F Jr,Costa-Paiva L,Morais SS,Pedro AO,Pinto-Neto AM

更新日期：2007-02-20 00:00:00

abstract：:Gender inequalities in the financial resources in later life result from the combined effect of women's atypical life courses, which include interrupted employment records and periods of care provision, and the fact that pension systems have generally been slow in mitigating 'diversions' from continuous and full-time ...

journal_title：Maturitas

authors： Vlachantoni A

更新日期：2012-06-01 00:00:00

abstract：OBJECTIVE:To determine whether individually tailored acupuncture is an effective treatment option for reducing postmenopausal hot flashes and improving quality of life. METHODS:In a randomized, placebo-controlled pilot study, 29 postmenopausal participants averaging at least seven moderate to severe hot flashes per 24...

journal_title：Maturitas

authors： Nir Y,Huang MI,Schnyer R,Chen B,Manber R

更新日期：2007-04-20 00:00:00

abstract：OBJECTIVES:To better define the longitudinal changes in renal function, to examine the associated risk factors, and to investigate whether there is an independent association of decline in renal function with presence of carotid plaque in a middle-aged and elderly healthy population. METHODS:245 healthy individuals (9...

journal_title：Maturitas

authors： Jiang S,Sun X,Gu H,Chen Y,Xi C,Qiao X,Chen X

更新日期：2012-11-01 00:00:00

abstract：OBJECTIVES:Bone mineral density (BMD) and development of osteoporosis are partly determined by genetic factors. The associations between one of suggested candidate, apolipoprotein E (apo E) genotype to bone mineral density (BMD) and bone biochemical markers was studied in 464 subjects recruited from a population-based ...

journal_title：Maturitas

authors： Heikkinen AM,Kröger H,Niskanen L,Komulainen MH,Ryynänen M,Parviainen MT,Tuppurainen MT,Honkanen R,Saarikoski S

更新日期：2000-01-15 00:00:00

abstract：OBJECTIVES:Osteoprotegerin (OPG) is a recently discovered member of the tumour necrosis factor receptor superfamily. It plays a crucial role in the control of bone resorption and its gene could therefore be a good candidate gene for osteoporosis. The aim of our work was to find polymorphisms in the OPG gene and to inve...

journal_title：Maturitas

authors： Arko B,Prezelj J,Kocijancic A,Komel R,Marc J

更新日期：2005-07-16 00:00:00

abstract：OBJECTIVES:There is evidence that menopausal symptoms manifested at peri-menopause occur less frequently when compared to the symptoms experienced at post-menopause. The aim of this study was to investigate this and to test the hypothesis that depressive symptomatology mediates the relationship between menopausal stage...

journal_title：Maturitas

authors： Borkoles E,Reynolds N,Thompson DR,Ski CF,Stojanovska L,Polman RC

更新日期：2015-06-01 00:00:00

abstract：OBJECTIVES:Our pilot study tested the efficacy, acceptability and tolerability of DHA supplementation in addition to calcium and vitamin D in individuals with osteopenia. STUDY DESIGN:40 participants were randomised to either algal oil containing 400mg docosahexanoic acid (DHA) daily or placebo. All participants recei...

journal_title：Maturitas

authors： Vanlint SJ,Ried K

更新日期：2012-01-01 00:00:00

abstract：INTRODUCTION:The use of menopausal hormone therapy (MHT) has decreased in many countries in the past 10 years. This is a consequence of the initial publication of the results of the Women's Health Initiative (WHI) randomized trial of estrogen plus progestin. In various countries, further studies then analyzed the incid...

journal_title：Maturitas

authors： Antoine C,Ameye L,Paesmans M,de Azambuja E,Rozenberg S

更新日期：2016-02-01 00:00:00

abstract：OBJECTIVES:Estrogen is often prescribed for symptoms and sequelae of ovarian estrogen loss after menopause. METHODS:To assess efficacy and acceptability of a new, highly soluble estrogen-calcium preparation, we formulated a water-soluble powdered combination of estrogen (0.625 mg estrone piperazine sulfate) and calciu...

journal_title：Maturitas

authors： Downey D,Spencer SJ,Deghenghi R,Jaffe RB

更新日期：2001-04-20 00:00:00

abstract：:Since the launch in 2008 by the National Osteoporosis Guideline Group (NOGG), of guidance for the diagnosis and management of osteoporosis in postmenopausal women and older men in the UK there have been significant advances in risk assessment and treatment. These have been incorporated into an updated version of the g...

journal_title：Maturitas

authors： Compston J,Bowring C,Cooper A,Cooper C,Davies C,Francis R,Kanis JA,Marsh D,McCloskey EV,Reid DM,Selby P,National Osteoporosis Guideline Group.

更新日期：2013-08-01 00:00:00

abstract：:Beneficial effects on health of limiting food intake for certain periods of time have been recognized for a long time. While many diets can produce short-term weight loss, most fail to result in a long-lasting impact. Current data suggest that intermittent fasting may be beneficial for overall health and wellbeing. Ho...

journal_title：Maturitas

authors： Skaznik-Wikiel ME,Polotsky AJ

更新日期：2014-11-01 00:00:00

abstract：:The effect of two forms of exogenous estrogen and a placebo on diastolic blood pressure and bodyweight was evaluated in 50 oophorectomized women. There was no significant change in bodyweight on any form of treatment, nor was there any significant elevation in mean diastolic blood pressure. However, 2 out of 49 female...

journal_title：Maturitas

authors： Utian WH

更新日期：1978-06-01 00:00:00

abstract：OBJECTIVE:Decision-making during menopause (especially surgical menopause) can be complex given the variability in risk-benefit perceptions of menopausal treatments. Decision aid tools (DATs) help women participate in decision-making about options. Our objective is to identify and evaluate the content and development o...

journal_title：Maturitas

authors： Siyam T,Sultani H,Ross S,Chatterley T,Yuksel N

更新日期：2017-12-01 00:00:00

abstract：AIM:The aim was to investigate bone mineral density (BMD) in breast cancer patients with positive estrogen receptor (ER) tumor status. METHODS:The participants were 110 postmenopausal breast cancer patients with positive estrogen receptor (ER+) tumor status. Two hundred and sixty-one age-matched, healthy postmenopausa...

journal_title：Maturitas

authors： Douchi T,Yonehara Y,Kosha S,Iwamoto I,Rai Y,Sagara Y,Umekita Y

更新日期：2007-07-20 00:00:00

abstract：OBJECTIVES:This paper aims to report the methodology of a study of a cohort of middle-aged women in Taiwan, their age at menopause, and related factors and prevalence of menopausal symptoms, and to examine the relationships between symptoms and sociodemographic variables. METHODS:An epidemiological study of neuropsych...

journal_title：Maturitas

authors： Fuh JL,Wang SJ,Lu SR,Juang KD,Chiu LM

更新日期：2001-08-25 00:00:00

abstract：:As the debate about the potential benefits and harms of screening mammography continues, it is timely to consider the role of clinical breast examination in screening for women at average risk of breast cancer. This article reviews the results from clinical trials and discusses the varied recommendations around the wo...

journal_title：Maturitas

authors： Brennan ME

更新日期：2016-10-01 00:00:00

abstract：:In direct contrast to the observational studies, both primary and secondary prevention trials of female reproductive hormones have found no benefit for coronary heart disease (CHD). Basic science studies have elucidated several mechanisms by which estrogen may improve coronary arterial physiology and prevent pathology...

journal_title：Maturitas

authors： Rossouw JE

更新日期：2005-05-16 00:00:00

abstract：:Gynecological literature is replete with multiple papers on sexually transmitted infections (STIs) in young women. Although those past the reproductive prime may well be at lower risk for STIs than women in the peak reproductive years, STIs are regularly seen in the older cohort and are a cause for significant morbidi...

journal_title：Maturitas

authors： Minkin MJ

更新日期：2010-10-01 00:00:00

abstract：:Heart disease is a major cause of death, disease and disability in the developed world for both men and women. Women appear to be under-diagnosed and treated both because they fail to visit the doctor or hospital with relevant symptoms and because doctors tend to dismiss the seriousness of women's symptoms of heart di...

journal_title：Maturitas

authors： Clarke J

更新日期：2010-03-01 00:00:00

abstract：OBJECTIVES:mitral annular calcification (MAC) occurs mainly in middle-aged and elderly patients and can lead to serious clinical consequences. Male predominance in the prevalence of coronary disease is well-established. Paradoxically, the prevalence of MAC, which is theoretically based on the same etiological mechanism...

journal_title：Maturitas

authors： Tenenbaum A,Fisman EZ,Pines A,Shemesh J,Shapira I,Adler Y,Frenkel Y,Boyko V,Motro M

更新日期：2000-07-31 00:00:00

abstract：:Despite the clear benefits of long-term hormone replacement therapy (HRT), the majority of patients tend to undergo short-term treatment. The cyclical bleedings induced by the sequential progestogen administration are often unacceptable namely in the elderly postmenopausal women. At the standard doses HRT preparations...

journal_title：Maturitas

authors： Gambacciani M,Genazzani AR

更新日期：2001-12-14 00:00:00

abstract：OBJECTIVES:To review some aspects in the recent literature related to the effects of postmenopausal estrogen and progestin use on major plasma lipoprotein risk factors for coronary heart disease (CHD). METHODS:Collection of relevant information from medical journals, and by the use of Medline and Current Contents. RE...

journal_title：Maturitas

authors： Tikkanen MJ

更新日期：1996-05-01 00:00:00

abstract：:Earlier menopause onset has been linked to a greater risk of cardiovascular disease. Both menopause onset and cardiovascular disease risk vary by geographical region, race/ethnicity and socioeconomic status. As such, it is plausible to hypothesize that these factors may influence the association of menopause onset and...

journal_title：Maturitas

authors： El Khoudary SR

更新日期：2020-11-01 00:00:00