The health pros and cons of continuous versus intermittent calorie restriction: more questions than answers.

abstract：AIMS:Women in the West can now expect to live one third of their life in a postmenopausal state, and consequently in a state of estrogen deficiency. This can have a number of consequences, and many women suffer vasomotor symptoms during the climacteric. Estrogen deficiency can also result in changes to the skin, hair, ...

journal_title：Maturitas

authors： Palacios S

更新日期：1999-11-01 00:00:00

abstract：INTRODUCTION:The use of menopausal hormone therapy (MHT) has decreased in many countries in the past 10 years. This is a consequence of the initial publication of the results of the Women's Health Initiative (WHI) randomized trial of estrogen plus progestin. In various countries, further studies then analyzed the incid...

journal_title：Maturitas

authors： Antoine C,Ameye L,Paesmans M,de Azambuja E,Rozenberg S

更新日期：2016-02-01 00:00:00

abstract：:Worldwide, the number of menopausal women is increasing. They present with complex medical issues that lie beyond the traditional scope of gynaecologists and general practitioners (GPs). The European Menopause and Andropause Society (EMAS) therefore provides a holistic model of care for healthy menopause (HM). The HM ...

journal_title：Maturitas

authors： Stute P,Ceausu I,Depypere H,Lambrinoudaki I,Mueck A,Pérez-López FR,van der Schouw YT,Senturk LM,Simoncini T,Stevenson JC,Rees M

更新日期：2016-10-01 00:00:00

abstract：CONTEXT AND OBJECTIVE:The aim of this study was to describe hot flushes in men with prostate cancer, and their treatment methods. METHOD:A systematic review was conducted of the literature indexed between 1966 and 2009 on the MEDLINE, the ISI Web of Knowledge, Cinahl and PsycINFO. Of 252 articles identified, 32 were s...

journal_title：Maturitas

authors： Frisk J

更新日期：2010-01-01 00:00:00

abstract：OBJECTIVES:The extent to which menopause influences wellbeing is unclear. We investigated the association between moderate-severely bothersome vasomotor symptoms (VMS) and psychological general wellbeing in women, aged 40-65 years, taking into account socio-demographic and lifestyle factors. STUDY DESIGN/MAIN OUTCOME ...

journal_title：Maturitas

authors： Gartoulla P,Bell RJ,Worsley R,Davis SR

更新日期：2015-08-01 00:00:00

abstract：:The specific profile of estrogens on cardiovascular risk, with limiting action on atherogenesis but a less clear protection on cardiovascular episodes, might be improved by other agonists of the estrogen receptor, such as isoflavones. By using a systematic search based on the electronic Medline database plus a hand-se...

journal_title：Maturitas

authors： Cano A,García-Pérez MA,Tarín JJ

更新日期：2010-11-01 00:00:00

abstract：:The incidence of breast cancer has continued to decrease each year at Wilford Hall United States Air Force Medical Center with the ever-increasing use of combined progestogen-oestrogen replacement therapy over the past 12 yr. By 1983, the overall incidence of breast cancer had fallen to 53.9:100 000. The lowest rate f...

journal_title：Maturitas

authors： Gambrell RD Jr

更新日期：1986-07-01 00:00:00

abstract：OBJECTIVES:We studied the effect of hormonal treatment on skin ageing in menopausal women. METHODS:Twenty-four patients (45-68 years; mean age, 54.9 years) without hormone treatment for at least 6 months were included. Patients were assigned to three therapy groups: 1, oestrogen only (Estraderm TTS 50) (n=6); 2, trans...

journal_title：Maturitas

authors： Sator PG,Schmidt JB,Sator MO,Huber JC,Hönigsmann H

更新日期：2001-07-25 00:00:00

abstract：:In Belgium, the contraceptive choices and views on completed family size were studied. The study involved a 2-page questionnaire; the 1st part was self-administered while the 2nd half of the questionnaire allowed for the physician to interview the respondents. The survey studied the demographic characteristics of th...

journal_title：Maturitas

authors： van Keep PA,Dewilde DM

更新日期：1988-01-01 00:00:00

abstract：INTRODUCTION:Strategies in case of high risk of breast cancer in BRCA1/2 mutation carriers are either intensive breast cancer screening or risk-reducing mastectomy (RRM). Both options have a high physical and psychosexual impact. The aim of this study is to investigate who chooses when to undergo RRM. METHODS:BRCA1/2 ...

journal_title：Maturitas

authors： van Driel CM,Eltahir Y,de Vries J,Jaspers JP,Oosterwijk JC,Mourits MJ,de Bock GH

更新日期：2014-02-01 00:00:00

abstract：:The present study had two objectives: (1) to register the prevalence of a number of climacteric complaints in a Danish general population cohort and (2) retrospectively to test the validity of an association between climacteric complaints, menopausal development, occurrence of life events and social background. A post...

journal_title：Maturitas

authors： Køster A,Davidsen M

更新日期：1993-11-01 00:00:00

abstract：OBJECTIVES:To develop and evaluate a 30-min online training for managers, in order to improve menopause-related knowledge, attitudes and confidence in having supportive discussions with women experiencing menopausal symptoms at work. The study also explored intentions and behaviour in terms of having conversations. ST...

journal_title：Maturitas

authors： Hardy C,Griffiths A,Hunter MS

更新日期：2019-02-01 00:00:00

abstract：:Tibolone (Livial) has advantages over other forms of hormone replacement therapy (HRT); it is easy to use and does not induce withdrawal bleeding in postmenopausal women. The evidence for the effect of tibolone on climacteric symptoms is reviewed and shows that tibolone is effective in reducing vasomotor symptoms and ...

journal_title：Maturitas

authors： Ross LA,Alder EM

更新日期：1995-02-01 00:00:00

abstract：OBJECTIVE:To analyze the effects of statin use on bone turnover markers (BTM), in participants from a large population-based cohort. SUBJECTS AND METHODS:Cross-sectional study that included 2431 subjects (1401 women and 930 men) from the Camargo Cohort. We analyzed the differences in serum BTM between statin or non-st...

journal_title：Maturitas

authors： Hernández JL,Olmos JM,Romaña G,Martinez J,Castillo J,Yezerska I,Ramos C,González-Macías J

更新日期：2013-05-01 00:00:00

abstract：:By establishing a statistical profile of the average sexual behaviour of women during the climacteric period, an attempt was made to determine what influence the climacteric had on female sexual activity. With the advancement of age, the sexual activity of women tends to decline. The menopause itself tends to further ...

journal_title：Maturitas

authors： Bottiglioni F,De Aloysio D

更新日期：1982-04-01 00:00:00

abstract：INTRODUCTION:Loss of muscle strength is associated with falls, which, in turn, are the main cause of hip fractures in elderly people. The factors that most influence loss of strength in elderly people are a decrease in muscle mass, i.e. sarcopenia, and an increase in fat, i.e. obesity. METHODS:A prospective randomized...

journal_title：Maturitas

authors： Malafarina V,Uriz-Otano F,Gil-Guerrero L,Iniesta R,Zulet MA,Martinez JA

更新日期：2013-10-01 00:00:00

abstract：:This study investigated the effect of ageing and reduction in ovarian function on whole blood serotonin levels and the effect of the oestrogen replacement in postmenopausal women on blood serotonin levels. Amenorrheic, natural postmenopausal and ovariectomised women had lower blood serotonin levels than regularly mens...

journal_title：Maturitas

authors： Gonzales GF,Carrillo C

更新日期：1993-07-01 00:00:00

abstract：:Dementia has often thought to be unavoidable and incurable. In recent years, risk factors, including lifestyle attributes, have been associated with the two commonest forms of dementia, Alzheimer's Disease and vascular dementia. There is also new evidence that the adult brain maintains plasticity and response to exter...

journal_title：Maturitas

authors： Flicker L

更新日期：2009-08-20 00:00:00

abstract：:Elderly subjects with cognitive disorders are at particularly high risk of adverse drug reactions (ADRs). The objectives of our systematic review were to describe the prevalence of ADRs in elderly patients with cognitive disorders, the different types of ADRs and the medications suspected of involvement; to describe w...

journal_title：Maturitas

authors： Kanagaratnam L,Dramé M,Trenque T,Oubaya N,Nazeyrollas P,Novella JL,Jolly D,Mahmoudi R

更新日期：2016-03-01 00:00:00

abstract：:In a population-based prospective study it was shown that weight, height, overweight, total body size, age at first birth, parity and age at menopause are risk factors for the development of endometrial cancer. The finding that the patients had had a higher oestrogen excretion level than the controls some time before ...

journal_title：Maturitas

authors： Baanders-van Halewijn EA,Poortman J

更新日期：1985-05-01 00:00:00

abstract：:Osteoarthritis (OA) is a common age-related disease that affects the tissues of the synovial joint, leading to loss of function and pain. It impacts on both patient morbidity and mortality. It is a complex, polygenic disease that lacks any large-effect susceptibility loci. Instead, OA susceptibility alleles individual...

journal_title：Maturitas

authors： Reynard LN,Loughlin J

更新日期：2012-03-01 00:00:00

abstract：OBJECTIVE:To determine the changes in levels of urinary NTx at the end of the 6th month of oral and transdermal hormone replacement therapy (HRT) and the effects of additional alendronate therapy for osteoporotic women. METHOD:Of 66 postmenopausal women 23 were treated with oral estradiol+norethisterone acetate (E+P),...

journal_title：Maturitas

authors： Posaci C,Altunyurt S,Islekel H,Saygili U,Altekin E,Onvural A,Onvural B

更新日期：2002-08-30 00:00:00

abstract：:Hormone replacement therapy may increase the quality of life of postmenopausal women. Any regimen need to offer long-term endometrial safety. It is a standard to consider the co-administration of a sequential progestogen when estrogen replacement should be initiated in non-hysterectomized women. It is almost impossibl...

journal_title：Maturitas

authors： Dören M

更新日期：2000-01-01 00:00:00

abstract：:The management of medications in persons with frailty presents challenges. There is evidence of inappropriate prescribing and a lack of consensus among healthcare professionals on the judicious use of medications, particularly for patients with more severe frailty. This study reviews the evidence on the use of commonl...

journal_title：Maturitas

authors： O'Caoimh R,Cornally N,McGlade C,Gao Y,O'Herlihy E,Svendrovski A,Clarnette R,Lavan AH,Gallagher P,William Molloy D

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND:The higher risk of women developing autoimmune diseases suggests that immune system is mediated by sex steroids. OBJECTIVE:To review the effects of aging and menopause in immune system. METHODS:A systematic review of in vitro, animal and human studies involving aging and menopause and immune system was car...

journal_title：Maturitas

authors： Gameiro CM,Romão F,Castelo-Branco C

更新日期：2010-12-01 00:00:00

abstract：OBJECTIVES:The purpose of this study was to determine the frequency with which hormone replacement therapy (HRT) was prescribed and to identify physician-related factors associated with the prescription of HRT in Spain. STUDY DESIGN:A descriptive cross-sectional survey based on a personal interview with a structured q...

journal_title：Maturitas

authors： Castelo-Branco C,Ferrer J,Palacios S,Cornago S

更新日期：2006-11-20 00:00:00

abstract：:Heart disease is a major cause of death, disease and disability in the developed world for both men and women. Women appear to be under-diagnosed and treated both because they fail to visit the doctor or hospital with relevant symptoms and because doctors tend to dismiss the seriousness of women's symptoms of heart di...

journal_title：Maturitas

authors： Clarke J

更新日期：2010-03-01 00:00:00

abstract：:Androgen insensitivity syndrome (AIS) is one of the most common sexual developmental disorders. According to the grade of the remaining androgen receptor (AR) function, AIS is classified as complete (CAIS), partial (PAIS) or mild (MAIS). In CAIS, the prevalence of germ cell tumours is increased compared with the gener...

journal_title：Maturitas

authors： Kosti K,Athanasiadis L,Goulis DG

更新日期：2019-09-01 00:00:00

abstract：OBJECTIVES:The aim of the study was to document sexual function in Kelantanese postmenopausal women. METHOD:A semi-structured questionnaire in Malay language was administered to 326 women (mean age of 57.1+/-6.58 (S.D.) years) residing in Kelantan. The subjects comprised of naturally menopaused, healthy women. RESULT...

journal_title：Maturitas

authors： Dhillon HK,Singh HJ,Ghaffar NA

更新日期：2005-11-01 00:00:00

abstract：OBJECTIVES:The aim of the present study was to evaluate the effects of low doses of hormone replacement therapy (HRT) in normal young postmenopausal women. METHODS:In an open trial healthy, non-obese postmenopausal women received for 2 years a low-dose continuous combined HRT (LD-HRT) containing 1mg estradiol+0.5 mg n...

journal_title：Maturitas

authors： Gambacciani M,Cappagli B,Ciaponi M,Pepe A,Vacca F,Genazzani AR

更新日期：2008-01-20 00:00:00