Abstract：
:The incidence of breast cancer has continued to decrease each year at Wilford Hall United States Air Force Medical Center with the ever-increasing use of combined progestogen-oestrogen replacement therapy over the past 12 yr. By 1983, the overall incidence of breast cancer had fallen to 53.9:100 000. The lowest rate for the 9 yr of a prospective study to 1983 was seen among the oestrogen-progestogen users (66.8:100 000) although it was also slightly reduced in both the unopposed oestrogen users (142.3:100 000 and the oestrogen vaginal cream users (116.3:100 000). The incidence was significantly lower in both the oestrogen-progestogen users and the oestrogen users (P less than or equal to 0.01) as compared with untreated women (343.5:100 000). These data further strengthen the growing evidence that the addition of progestogen to oestrogen decreases the risk of mammary malignancy.
journal_name
Maturitasjournal_title
Maturitasauthors
Gambrell RD Jrdoi
10.1016/0378-5122(86)90023-xsubject
Has Abstractpub_date
1986-07-01 00:00:00pages
169-76issue
2eissn
0378-5122issn
1873-4111pii
0378-5122(86)90023-Xjournal_volume
8pub_type
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