Abstract:
BACKGROUND AND OBJECTIVES:Cutaneous intrinsic ageing has been shown to be improved by hormone replacement therapy (HRT). Photoageing is, however, unresponsive to such treatment. The present double-blind study was undertaken to compare the beneficial effect of a 1-month topical treatment with 0.05% all-trans-retinoic acid or 6% glycolic acid. METHOD:Biomechanical properties were measured on facial skin of HRT-treated menopausal women using both topical products on the hemifaces for 1 month. RESULTS:Skin elasticity proved to be significantly higher at the tretinoin-treated site than at the glycolic acid-treated site. CONCLUSION:Objective non-invasive measurements of the biomechanical properties of facial skin show the superiority of retinoic acid over glycolic acid in improving a deleterious effect of ageing.
journal_name
Maturitasjournal_title
Maturitasauthors
Piérard GE,Henry F,Piérard-Franchimont Cdoi
10.1016/0378-5122(95)00983-3subject
Has Abstractpub_date
1996-04-01 00:00:00pages
273-7issue
3eissn
0378-5122issn
1873-4111pii
0378512295009833journal_volume
23pub_type
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