Models for estimating the biological age of five organs using clinical biomarkers that are commonly measured in clinical practice settings.

abstract：:Peyronie's disease is an incurable, sexually debilitating fibrotic disease of the penis that results in penile curvature, coital failure, and significant psychological stress for patients and their partners. Appropriate treatment should be individualized and tailored to the patient's goals and expectations, disease hi...

journal_title：Maturitas

authors： Langston JP,Carson CC 3rd

更新日期：2014-08-01 00:00:00

abstract：:The menopausal syndrome is characterized by a variety of emotional and physical symptoms of varying intensity. A total of 1287 women who attended the Outpatient Department for Climacteric Symptoms and Osteoporosis Prophylaxis (1st Department of Gynaecology and Obstetrics, University of Vienna Medical School) constitut...

journal_title：Maturitas

authors： Metka M,Enzelsberger H,Knogler W,Schurz B,Aichmair H

更新日期：1991-12-01 00:00:00

abstract：:Within the last decade, breast cancer is increasingly understood as a heterogeneous disease comprising distinct entities that vary significantly with regard to molecular biology and clinical features. Despite impressive advances in the treatment of patients with breast cancer, not all patients derive equal benefits fr...

journal_title：Maturitas

authors： Liedtke C,Kiesel L

更新日期：2012-12-01 00:00:00

abstract：OBJECTIVES:To evaluate the association between treatments for vulvovaginal atrophy (VVA) and symptom frequency and severity, quality of life (QoL) and sexual functioning in postmenopausal women. STUDY DESIGN:Cross-sectional survey conducted in postmenopausal women aged 45-75 years. Data on demographic and clinical var...

journal_title：Maturitas

authors： Panay N,Palacios S,Bruyniks N,Particco M,Nappi RE,EVES Study investigators.

更新日期：2019-06-01 00:00:00

abstract：:Components of the metabolic syndrome (MetS), including abdominal obesity, low-grade chronic systemic inflammation, altered glucose metabolism, dyslipidemia and high blood pressure, are major threats to healthy aging in modern societies. The connection between MetS components and gut microflora is now acknowledged and ...

journal_title：Maturitas

authors： O'Connor S,Chouinard-Castonguay S,Gagnon C,Rudkowska I

更新日期：2017-10-01 00:00:00

abstract：:Epidemiological studies have shown that cigarette smoking is associated with an increased risk of midlife hot flashes; however, the effect of quitting smoking on this risk is unclear. The purpose of this study was to examine the effect of quitting smoking on hot flashes using data from 761 women aged 45 to 54 years of...

journal_title：Maturitas

authors： Smith RL,Flaws JA,Gallicchio L

更新日期：2015-09-01 00:00:00

abstract：:Gonadotropin levels were determined in 17 postmenopausal women before and after administering a single depot-dose of the GnRH agonist triptorelin. E2 levels of all samples were in the normal (low) postmenopausal range and no differences were found when the patients were grouped according to chronological age, or time ...

journal_title：Maturitas

authors： Sluijmer AV,Heineman MJ,De Leeuw R,Evers JL

更新日期：1994-11-01 00:00:00

abstract：OBJECTIVE:To evaluate changes in mammographic density and (99m)Tc-sestamibi scintimammographic uptake in postmenopausal women on hormone replacement therapy (HRT). METHODS:Seventy-five postmenopausal women were prospectively studied and allocated into three groups: 50 women were randomized to either Group 1 (G1, n=25)...

journal_title：Maturitas

authors： Nahas-Neto J,Luca LA,Griva BL,Morceli J,Nahas EA,Moriguchi SM,Uemura G,Traiman P

更新日期：2006-01-10 00:00:00

abstract：:In direct contrast to the observational studies, both primary and secondary prevention trials of female reproductive hormones have found no benefit for coronary heart disease (CHD). Basic science studies have elucidated several mechanisms by which estrogen may improve coronary arterial physiology and prevent pathology...

journal_title：Maturitas

authors： Rossouw JE

更新日期：2005-05-16 00:00:00

abstract：OBJECTIVES:To explore any feelings and symptoms surrounding menopause among Mayan women in three ethnolinguistic groups in highland Guatemala and compare these with previous reports from Mexico. METHODS:This was a qualitative exploratory study of the experiences around menopause of eight middle aged women and one loca...

journal_title：Maturitas

authors： Stewart DE

更新日期：2003-04-25 00:00:00

abstract：:Age-related changes in the concentrations of the main plasma electrolytes and in the urinary excretion of some of these ions have been examined in 436 pre-menopausal and 117 post-menopausal women. The main changes up to the menopause were decreases in the mean plasma potassium, calcium and total protein concentrations...

journal_title：Maturitas

authors： Hodgkinson A

更新日期：1982-12-01 00:00:00

abstract：:Tibolone appears to be at least as efficacious as other forms of hormonal replacement therapy (HRT) on climacteric symptoms. It does not cause withdrawal bleeding when used in women with at least 1 year of amenorrhea. It is, therefore, not indicated in perimenopause because it may cause irregular bleeding. The androge...

journal_title：Maturitas

authors： Albertazzi P,Di Micco R,Zanardi E

更新日期：1998-11-16 00:00:00

abstract：OBJECTIVES:To study the fracture reducing potential of hormonal replacement therapy (HRT) in recent postmenopausal women in a primary preventive scenario. METHODS:Prospective controlled comprehensive cohort trial: 2016 healthy women aged 45-58 years, from three to 24 months past last menstrual bleeding were recruited ...

journal_title：Maturitas

authors： Mosekilde L,Beck-Nielsen H,Sørensen OH,Nielsen SP,Charles P,Vestergaard P,Hermann AP,Gram J,Hansen TB,Abrahamsen B,Ebbesen EN,Stilgren L,Jensen LB,Brot C,Hansen B,Tofteng CL,Eiken P,Kolthoff N

更新日期：2000-10-31 00:00:00

abstract：:The aim of this review was to systematically assess the effectiveness of aromatherapy for stress management. Seven databases were searched from their inception through April 2014. RCTs testing aromatherapy against any type of controls in healthy human person that assessed stress level and cortisol level were considere...

journal_title：Maturitas

authors： Hur MH,Song JA,Lee J,Lee MS

更新日期：2014-12-01 00:00:00

abstract：OBJECTIVES:25-hydroxyvitamin D [25(OH)D] deficiency is related to an increase in cardiovascular risk but the association between low 25(OH)D and hospitalization and mortality in heart failure (HF) patients remains unclear. The objective of this study was therefore to determine whether 25(OH)D deficiency is associated w...

journal_title：Maturitas

authors： Aparicio-Ugarriza R,Salguero D,Mohammed YN,Ferri-Guerra J,Baskaran DJ,Mirabbasi SA,Rodriguez A,Ruiz JG

更新日期：2020-02-01 00:00:00

abstract：OBJECTIVES:It is still controversial whether hormone replacement therapy (HRT) can affect the onset of uterine myomas or their growth in postmenopause. It is likely that some therapeutic schedules can influence the myometrial growth differently, due to a more potent stimulation of the uterine receptors. The aim of the ...

journal_title：Maturitas

authors： Polatti F,Viazzo F,Colleoni R,Nappi RE

更新日期：2000-11-30 00:00:00

abstract：:Climacteric symptoms were investigated among healthy women living in and around a small town in Tanzania. The incidence of symptoms was high and similar to that recorded in Western societies. Statistically significant associations were observed between some symptoms and the number of years since menopause. More attent...

journal_title：Maturitas

authors： Moore B,Kombe H

更新日期：1991-09-01 00:00:00

abstract：OBJECTIVES:Study to compare the effects of tibolone and raloxifene on health-related quality of life, sexuality and vaginal atrophy. METHODS:A double-blind, randomized study was conducted in 308 osteopenic, but otherwise healthy, postmenopausal women (mean age 66 years) who received tibolone 1.25mg/day or raloxifene 6...

journal_title：Maturitas

authors： Nijland EA,Weijmar Schultz WC,Davis SR

更新日期：2007-10-20 00:00:00

abstract：OBJECTIVE:The objective of this study was to determine the relationships of serum estrogen levels after hormone replacement therapy (HRT) every other day and every day with body mass index (BMI) in postmenopausal and bilaterally ovariectomized women. METHODS:Eighty-six postmenopausal and 51 bilaterally ovariectomized ...

journal_title：Maturitas

authors： Yasui T,Uemura H,Umino Y,Takikawa M,Saito S,Kuwahara A,Matsuzaki T,Maegawa M,Furumoto H,Miura M,Irahara M

更新日期：2005-01-10 00:00:00

abstract：OBJECTIVES:The objectives of the study were to find the prevalence of major depressive disorder (MDD) in male climacteric outpatients in Japan, and to determine whether symptoms on the Aging Males' Symptoms (AMS) scale scores differed between patients with and without MDD, with the aim of increasing the specificity of ...

journal_title：Maturitas

authors： Yoshida NM,Kumano H,Kuboki T

更新日期：2006-01-20 00:00:00

abstract：:Most health decisions occur in contexts of scientific uncertainty, the "grey zone" of decision-making and many decisions faced by menopausal women are no exception. These contexts are characterized either by scientific evidence that points to a balance between harms and benefits within or between options, or by the ab...

journal_title：Maturitas

authors： Légaré F,Brouillette MH

更新日期：2009-07-20 00:00:00

abstract：:This is a scoping review of the notions of authenticity and citizenship in the context of understanding dementia. Authenticity suggests being true to yourself. Social citizenship suggests engagement, relationships and rights. The literature which links authenticity to dementia is scanty, albeit the notion suggests num...

journal_title：Maturitas

authors： Hughes JC

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:Previously, the REDLINC VI study showed that the main reason for the low use of menopausal hormone therapy (MHT) was its low rate of prescription by doctors. OBJECTIVE:To determine the use of MHT and perceived related risks among gynecologists. METHODS:A self-administered and anonymous questionnaire was de...

journal_title：Maturitas

authors： Danckers L,Blümel JE,Witis S,Vallejo MS,Tserotas K,Sánchez H,Salinas C,Saavedra J,Rojas JA,Onatra W,Ojeda E,Mostajo D,Morera F,Monterrosa A,Montaño A,Meruvia N,Martino M,Martínez J,Lima S,González E,Gómez G,Espi

更新日期：2016-05-01 00:00:00

abstract：:Androgen insensitivity syndrome (AIS) is one of the most common sexual developmental disorders. According to the grade of the remaining androgen receptor (AR) function, AIS is classified as complete (CAIS), partial (PAIS) or mild (MAIS). In CAIS, the prevalence of germ cell tumours is increased compared with the gener...

journal_title：Maturitas

authors： Kosti K,Athanasiadis L,Goulis DG

更新日期：2019-09-01 00:00:00

abstract：:The aim of this trial was to study the vaginal absorption of oestriol and to investigate whether morning rather than evening oestriol administration would produce different plasma oestriol patterns. The influence of food intake on plasma oestriol levels was also investigated. Nine post-menopausal women were given 0.5 ...

journal_title：Maturitas

authors： Heimer GM,Englund DE

更新日期：1986-10-01 00:00:00

abstract：:Gynaecologists have been criticized in recent years because of their attitude towards hysterectomy; it is often stated that they are too ready to consider hysterectomy to be indicated and that hysterectomies are carried out too frequently. In order to obtain insight into the incidence of hysterectomy, 2066 women betwe...

journal_title：Maturitas

authors： van Keep PA,Wildemeersch D,Lehert P

更新日期：1983-08-01 00:00:00

abstract：OBJECTIVES:Qualitative studies show that women link menopause to the ageing process, and yet surprisingly little research has investigated how attitudes to ageing might shape women's experience of menopause, as well as their overall well-being at midlife. This study validated the Attitudes to Ageing Questionnaire (AAQ)...

journal_title：Maturitas

authors： Brown L,Bowden S,Bryant C,Brown V,Bei B,Gilson KM,Komiti A,Judd F

更新日期：2015-10-01 00:00:00

abstract：OBJECTIVES:The purpose of this review is to focus on the importance of metabolic syndrome (MBS) and its increased prevalence in postmenopausal (PM) women. Also the role of hormonal therapy in PM women with MBS will be discussed. METHODS:Review of the relevant literature and results from recent clinical trials. RESULT...

journal_title：Maturitas

authors： Lobo RA

更新日期：2008-05-20 00:00:00

abstract：:The endometrial effect of long-term vaginal oestriol (E3) therapy for urogenital atrophy was assessed in 23 post-menopausal women. Hysteroscopic and histological examinations were performed in each patient to assess endometrial atrophy before treatment and after 6 and 12 months of therapy (0.5 mg vaginal E3 for 21 day...

journal_title：Maturitas

authors： Gerbaldo D,Ferraiolo A,Croce S,Truini M,Capitanio GL

更新日期：1991-10-01 00:00:00

abstract：OBJECTIVES:To compare the metabolic and endocrinological effects of estradiol valerate/cyproterone acetate (EV/CPA) to a regimen of conjugated estrogens/medroxyprogesterone acetate (CE/MPA) in postmenopausal women. METHODS:Lipid profile, endocrinological parameters, coagulation factors, renin and angiotensinogen were ...

journal_title：Maturitas

authors： Bissonnette F,Lussier-Cacan S,Fugère P,Bérubé S

更新日期：1997-07-01 00:00:00