Abstract：
OBJECTIVE:The use of hormone replacement therapy (HRT) declined strongly in many countries after publication of the WHI-study. The purpose of the present study was to investigate HRT usage patterns and motives for initiation, temporary discontinuation, and permanent discontinuation of HRT use among Norwegian women. METHODS:A questionnaire study about use and attitudes towards HRT was carried out in 2005. Women 45-64 years old were invited to the study (n=2325, response rate 47%). RESULTS:Women initiated HRT use mainly due to climacteric complaints (74%), while prophylactic motives were less frequently reported (27%). The most often reported benefits of HRT use were reduced climacterical symptoms, especially hot flushes/sweating (83%), and improved quality of life (59%). The major proportion of ever-users (57%) had at some point temporarily discontinued HRT use. The motive for temporary discontinuation of HRT use most frequently reported was to see if climacterical symptoms had ceased (58%). Permanent discontinuation of HRT use was most often motivated by anxiety to side effects (55%). In multivariable analyses, women using HRT prophylactically were less likely to temporarily discontinue use. Women with a positive attitude towards HRT were the most unlikely ones to permanently discontinue HRT use. CONCLUSIONS:Temporary discontinuation of HRT use was common among Norwegian women. The majority of HRT users reported a reduction in climacteric complaints after initiation of HRT use but many women were afraid of side effects.
journal_name
Maturitasjournal_title
Maturitasauthors
Øren Adoi
10.1016/j.maturitas.2009.07.010subject
Has Abstractpub_date
2009-09-20 00:00:00pages
33-7issue
1eissn
0378-5122issn
1873-4111pii
S0378-5122(09)00229-1journal_volume
64pub_type
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