Hearing loss and the risk of dementia in later life.

abstract：:In the present study, unopposed oestrogens were given to 184 non-hysterectomized women, for a duration varying from four weeks to 24 months, while the endometrial responses were monitored by transvaginal sonography (TVS) and backed up by endometrial sampling (conducted when the endometrial thickness reached 8 mm (doub...

journal_title：Maturitas

authors： Meuwissen JH,Oddens BJ,Klinkhamer PJ

更新日期：1996-05-01 00:00:00

abstract：:Within the last decade, breast cancer is increasingly understood as a heterogeneous disease comprising distinct entities that vary significantly with regard to molecular biology and clinical features. Despite impressive advances in the treatment of patients with breast cancer, not all patients derive equal benefits fr...

journal_title：Maturitas

authors： Liedtke C,Kiesel L

更新日期：2012-12-01 00:00:00

abstract：AIMS:Women in the West can now expect to live one third of their life in a postmenopausal state, and consequently in a state of estrogen deficiency. This can have a number of consequences, and many women suffer vasomotor symptoms during the climacteric. Estrogen deficiency can also result in changes to the skin, hair, ...

journal_title：Maturitas

authors： Palacios S

更新日期：1999-11-01 00:00:00

abstract：OBJECTIVE:Early onset of menopause results in the premature exposure to low estrogen levels and is associated with a number of postmenopausal health problems and higher risk of mortality. The aim of this study was to determine genetic and environmental factors associated with age at natural and surgical menopause. MET...

journal_title：Maturitas

authors： Dvornyk V,Long JR,Liu PY,Zhao LJ,Shen H,Recker RR,Deng HW

更新日期：2006-04-20 00:00:00

abstract：OBJECTIVE:Social support interventions for caregivers of persons with dementia (PwD) are important because informal carers often rely on their social networks for support. This systematic review synthesises findings from research on social support interventions, and examines their methodological quality and effectivene...

journal_title：Maturitas

authors： Dam AE,de Vugt ME,Klinkenberg IP,Verhey FR,van Boxtel MP

更新日期：2016-03-01 00:00:00

abstract：OBJECTIVES:To analyze independently in men and women the incidence rate of and risk factors for hip fracture in a southern European population. Illiteracy, dementia, clinically significant depression and disability were factors to receive special emphasis. STUDY DESIGN:A community sample of 4803 individuals aged over ...

journal_title：Maturitas

authors： Lobo E,Marcos G,Santabárbara J,Salvador-Rosés H,Lobo-Escolar L,De la Cámara C,Aso A,Lobo-Escolar A,ZARADEMP Workgroup.

更新日期：2017-03-01 00:00:00

abstract：:The effect of two forms of exogenous estrogen and a placebo on diastolic blood pressure and bodyweight was evaluated in 50 oophorectomized women. There was no significant change in bodyweight on any form of treatment, nor was there any significant elevation in mean diastolic blood pressure. However, 2 out of 49 female...

journal_title：Maturitas

authors： Utian WH

更新日期：1978-06-01 00:00:00

abstract：:Insomnia, vasomotor symptoms (VMS) and depression often co-occur after the menopause, with consequent health problems and reductions in quality of life. The aim of this position statement is to provide evidence-based advice on the management of postmenopausal sleep disorders derived from a systematic review of the lit...

journal_title：Maturitas

authors： Silvestri R,Aricò I,Bonanni E,Bonsignore M,Caretto M,Caruso D,Di Perri MC,Galletta S,Lecca RM,Lombardi C,Maestri M,Miccoli M,Palagini L,Provini F,Puligheddu M,Savarese M,Spaggiari MC,Simoncini T

更新日期：2019-11-01 00:00:00

abstract：:Ageing is accompanied with a progressive loss of muscle mass and force generating capacity. Ultimately, the muscle wasting and weakness may dramatically impact on mobility and the quality of life, where the elderly has increasing problems with performing activities of daily life, such as rising from a chair or climbin...

journal_title：Maturitas

authors： Degens H,Korhonen MT

更新日期：2012-11-01 00:00:00

abstract：OBJECTIVES:To study whether dose adjustments in transdermal estradiol gel treatment would result in proportional changes in estradiol bioavailability and concentrations. METHODS:In an open study, 23 healthy postmenopausal women were treated consecutively with 0.5, 1.0 and 1.5 mg estradiol daily as a transdermal gel. E...

journal_title：Maturitas

authors： Järvinen A,Granander M,Laine T,Viitanen A

更新日期：2000-04-28 00:00:00

abstract：:The aim of the study was to investigate the influence of long-term administration of oral contraceptives on bone density in climacteric women. The existence of a correlation between long-term use and bone density was confirmed. ...

journal_title：Maturitas

authors： Enzelsberger H,Metka M,Heytmanek G,Schurz B,Kurz C,Kusztrich M

更新日期：1988-03-01 00:00:00

abstract：OBJECTIVE:Elevation of blood pressure and heart rate increase the risk of cardiovascular disease. Administration of estrogens does not affect heart rate but may decrease 24 h blood pressure. In this study, we tested the effect of the estro-progestogenic compound tibolone. METHODS:Thirty healthy, post-menopausal women ...

journal_title：Maturitas

authors： Cagnacci A,Baldassari F,Arangino S,Alessandrini C,Volpe A

更新日期：2004-06-15 00:00:00

abstract：:Hormone replacement therapy (HRT) in postmenopausal women is associated with a reduction in the risk of developing coronary artery disease (CAD) of about 50%. Women with an elevated risk for CAD appear to benefit most by HRT. The HRT-associated cardiovascular protection may be related to favourable changes in several ...

journal_title：Maturitas

authors： van der Mooren MJ,Mijatovic V,van Baal WM,Stehouwer CD

更新日期：1998-09-20 00:00:00

abstract：:Stroke represents one of the most important menaces to public health. A number of modifiable and non-modifiable risk factors have been identified and studied in detail; among those, obesity, the new world epidemic, seems to be one of the most important in terms of prevention. The discovery of the secretory role of the...

journal_title：Maturitas

authors： Savopoulos C,Michalakis K,Apostolopoulou M,Miras A,Hatzitolios A

更新日期：2011-12-01 00:00:00

abstract：:With ageing populations a major challenge is to maintain physical and cognitive function, quality of life and independence. The literature does not only indicate important gender differences in lifestyle behaviours, but also how these behaviours might affect health outcomes. The current review has a male perspective w...

journal_title：Maturitas

authors： Södergren M

更新日期：2013-06-01 00:00:00

abstract：:Similar to their US counterparts, Costa Rican women enter menopause at ∼50 years of age, have similar symptoms, including hot flashes and night sweats, as well as an overall negative attitude toward the menopausal transition. One study of rural women in Monteverde reported that women knew little about the menopausal t...

journal_title：Maturitas

authors： Locklear TD,Doyle BJ,Perez AL,Wicks SM,Mahady GB

更新日期：2017-10-01 00:00:00

abstract：:Unpaid, informal carers play a vital role in supporting people with long-term conditions. Being a carer can be challenging and carers may need support but they frequently fail to access it. Compared to research investigating the experiences of female carers, research with male carers is underdeveloped. The available e...

journal_title：Maturitas

authors： Greenwood N,Smith R

更新日期：2015-10-01 00:00:00

abstract：:A group of 72 postmenopausal women were treated for 4 weeks with vaginal suppositories containing 0.5 or 1.0 mg of estriol. The two different doses achieved an identical significant improvement of urogenital symptoms, while a dose-related effect seen to be on climacteric complaints, according to a good absorption of e...

journal_title：Maturitas

authors： Bottiglione F,Volpe A,Esposito G,Aloysio DD

更新日期：1995-11-01 00:00:00

abstract：:The endometrial effect of long-term vaginal oestriol (E3) therapy for urogenital atrophy was assessed in 23 post-menopausal women. Hysteroscopic and histological examinations were performed in each patient to assess endometrial atrophy before treatment and after 6 and 12 months of therapy (0.5 mg vaginal E3 for 21 day...

journal_title：Maturitas

authors： Gerbaldo D,Ferraiolo A,Croce S,Truini M,Capitanio GL

更新日期：1991-10-01 00:00:00

abstract：OBJECTIVE:To assess beneficial effects of a soy rich diet on the main biomarkers of cardiovascular health in menopause, compared with the effects of the hormone replacement therapy (HRT). METHODS:187 healthy asymptomatic postmenopausal women, aged 39-60, were recruited and randomized into three groups: a soy rich diet...

journal_title：Maturitas

authors： Chiechi LM,Secreto G,Vimercati A,Greco P,Venturelli E,Pansini F,Fanelli M,Loizzi P,Selvaggi L

更新日期：2002-02-26 00:00:00

abstract：:From a longitudinal prospective study, 160 women with spontaneous menopause and without steroid medication were followed during the transition from pre- to postmenopause. After 12 years 152 women were still participating in the study. Blood samples were drawn every 6 months until 1 year after the menopause and every 1...

journal_title：Maturitas

authors： Rannevik G,Jeppsson S,Johnell O,Bjerre B,Laurell-Borulf Y,Svanberg L

更新日期：2008-09-01 00:00:00

abstract：OBJECTIVES:C-telopeptide crosslaps (CTX) and bone-specific alkaline phosphatase (BAP) do not provide sufficient sensitivity and specificity for diagnosis of osteoporosis. Cathepsin K (CatK), osteoprotegerin (OPG), and receptor activator of nuclear factor κB ligand (total (t) and soluble (s) RANKL) play an important rol...

journal_title：Maturitas

authors： Piatek S,Adolf D,Wex T,Halangk W,Klose S,Westphal S,Amthauer H,Winckler S

更新日期：2013-04-01 00:00:00

abstract：OBJECTIVE:New regimens and routes of administration of hormonal replacement therapy (HRT) in climateric women are becoming available. Since there is no information on the neuroendocrine effects of sequential combined treatment with 17 beta-estradiol and a progestin, the present study evaluated the neuroendocrine, clini...

journal_title：Maturitas

authors： Stomati M,Bersi C,Rubino S,Palumbo M,Comitini G,Genazzani AD,Santuz M,Petraglia F,Genazzani AR

更新日期：1997-12-15 00:00:00

abstract：:Burning mouth syndrome associated to vulvodynia (Vulvostomatodynia) is a rare condition and is often difficult to diagnose and treat. Tongue, lips, vestibule and others mucosal sites may be affected by a tiresome burning sensation, especially in menopausal and postmenopausal women. Patients seldom report genital sympt...

journal_title：Maturitas

authors： Petruzzi M,De Benedittis M,Pastore L,Serpico R

更新日期：2007-09-20 00:00:00

abstract：:In direct contrast to the observational studies, both primary and secondary prevention trials of female reproductive hormones have found no benefit for coronary heart disease (CHD). Basic science studies have elucidated several mechanisms by which estrogen may improve coronary arterial physiology and prevent pathology...

journal_title：Maturitas

authors： Rossouw JE

更新日期：2005-05-16 00:00:00

abstract：OBJECTIVES:It has become popular to assert that Asian women in general have low midlife rates of reporting a wide variety of symptoms and that these rates are much lower than those found among women in western countries. Comparable data from mainland China remains sparse, however. This study aimed to uncover the sympto...

journal_title：Maturitas

authors： Shea JL

更新日期：2006-08-20 00:00:00

abstract：OBJECTIVES:The aim of the study was to document sexual function in Kelantanese postmenopausal women. METHOD:A semi-structured questionnaire in Malay language was administered to 326 women (mean age of 57.1+/-6.58 (S.D.) years) residing in Kelantan. The subjects comprised of naturally menopaused, healthy women. RESULT...

journal_title：Maturitas

authors： Dhillon HK,Singh HJ,Ghaffar NA

更新日期：2005-11-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to evaluate the prevalence of depressive symptoms in peri- and post-menopausal Taiwanese women, and to investigate the relation between depressive symptoms and demographic variables, chronic disease status, health habits, stress management, menopausal symptoms, and attitudes towa...

journal_title：Maturitas

authors： Wang HL,Booth-LaForce C,Tang SM,Wu WR,Chen CH

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:Cardiovascular disease (CVD) is the leading cause of death in women after menopause. In essence major risk factors for CVD are similar in women as for men inclusive of serum lipid perturbations. The effects of estrogens and hormone replacement therapy on lipid metabolism is widely discussed and warrant furth...

journal_title：Maturitas

authors： Nerbrand C,Nyberg P,Nordström L,Samsioe G

更新日期：2002-05-20 00:00:00

abstract：OBJECTIVES:The purpose of this review is to summarize the effectiveness of select vitamins, minerals and trace elements in postmenopausal women for their effects on bone health, cardiovascular health, breast cancer, cognition and vasomotor symptoms. METHODS:Review of the relevant literature and results from recent cli...

journal_title：Maturitas

authors： Dennehy C,Tsourounis C

更新日期：2010-08-01 00:00:00