Deprescribing in older people.

abstract：OBJECTIVES:To evaluate the effect of estrogen replacement therapy (ERT) on postmenopausal bone loss by multi-site ultrasound measurement. METHODS:A cross-sectional comparison of postmenopausal women, ERT users and non-users. The two study groups were enrolled for the reference database collection for the Sunlight Omni...

journal_title：Maturitas

authors： Weiss M,Ben Shlomo A,Hagag P,Rapoport M,Ish-Shalom S

更新日期：2000-06-30 00:00:00

abstract：OBJECTIVES:Estrogens modulate lipid metabolism and the increased risk of atherosclerosis in postmenopausal women is at least partly due to the reduction of estrogen production after menopause. We studied the effect of menopause on the contents of long-chain fatty acids, free cholesterol (FC) and cholesterol ester (CE) ...

journal_title：Maturitas

authors： Jokela H,Salomäki A,Lehtimäki T,Teisala K,Heinonen PK,Aine R,Rontu R,Punnonen R

更新日期：2004-02-20 00:00:00

abstract：OBJECTIVES:The purpose of this study was to determine the frequency with which hormone replacement therapy (HRT) was prescribed and to identify physician-related factors associated with the prescription of HRT in Spain. STUDY DESIGN:A descriptive cross-sectional survey based on a personal interview with a structured q...

journal_title：Maturitas

authors： Castelo-Branco C,Ferrer J,Palacios S,Cornago S

更新日期：2006-11-20 00:00:00

abstract：:Epidemiological studies have shown that cigarette smoking is associated with an increased risk of midlife hot flashes; however, the effect of quitting smoking on this risk is unclear. The purpose of this study was to examine the effect of quitting smoking on hot flashes using data from 761 women aged 45 to 54 years of...

journal_title：Maturitas

authors： Smith RL,Flaws JA,Gallicchio L

更新日期：2015-09-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to evaluate the prevalence of depressive symptoms in peri- and post-menopausal Taiwanese women, and to investigate the relation between depressive symptoms and demographic variables, chronic disease status, health habits, stress management, menopausal symptoms, and attitudes towa...

journal_title：Maturitas

authors： Wang HL,Booth-LaForce C,Tang SM,Wu WR,Chen CH

更新日期：2013-08-01 00:00:00

abstract：:With ageing populations a major challenge is to maintain physical and cognitive function, quality of life and independence. The literature does not only indicate important gender differences in lifestyle behaviours, but also how these behaviours might affect health outcomes. The current review has a male perspective w...

journal_title：Maturitas

authors： Södergren M

更新日期：2013-06-01 00:00:00

abstract：:Tibolone appears to be at least as efficacious as other forms of hormonal replacement therapy (HRT) on climacteric symptoms. It does not cause withdrawal bleeding when used in women with at least 1 year of amenorrhea. It is, therefore, not indicated in perimenopause because it may cause irregular bleeding. The androge...

journal_title：Maturitas

authors： Albertazzi P,Di Micco R,Zanardi E

更新日期：1998-11-16 00:00:00

abstract：:The mean plasma anion gap (Na + K + Ca + Mg)--(Cl + HCO3(-) + HPO4(2-) + protein), was significantly higher in post-menopausal women compared with pre-menopausal women (8.04 mEq/l compared with 7.03 mEq/l). This change was due, in part, to an increase in the plasma lactate concentration and to smaller increases in cit...

journal_title：Maturitas

authors： Hodgkinson A,Jones MM,Marshall RW,Skerrow SM

更新日期：1984-03-01 00:00:00

abstract：OBJECTIVES:To study the fracture reducing potential of hormonal replacement therapy (HRT) in recent postmenopausal women in a primary preventive scenario. METHODS:Prospective controlled comprehensive cohort trial: 2016 healthy women aged 45-58 years, from three to 24 months past last menstrual bleeding were recruited ...

journal_title：Maturitas

authors： Mosekilde L,Beck-Nielsen H,Sørensen OH,Nielsen SP,Charles P,Vestergaard P,Hermann AP,Gram J,Hansen TB,Abrahamsen B,Ebbesen EN,Stilgren L,Jensen LB,Brot C,Hansen B,Tofteng CL,Eiken P,Kolthoff N

更新日期：2000-10-31 00:00:00

abstract：:The increasing prevalence of diabetes especially type 2 diabetes worldwide is indisputable. Diabetics suffer increased morbidity and mortality, compared to their non-diabetic counterparts, not only because of vascular complications, but also because of an increased fracture incidence. Both types 1 and 2 diabetes and s...

journal_title：Maturitas

authors： Antonopoulou M,Bahtiyar G,Banerji MA,Sacerdote AS

更新日期：2013-11-01 00:00:00

abstract：OBJECTIVE:To determine whether individually tailored acupuncture is an effective treatment option for reducing postmenopausal hot flashes and improving quality of life. METHODS:In a randomized, placebo-controlled pilot study, 29 postmenopausal participants averaging at least seven moderate to severe hot flashes per 24...

journal_title：Maturitas

authors： Nir Y,Huang MI,Schnyer R,Chen B,Manber R

更新日期：2007-04-20 00:00:00

abstract：OBJECTIVES:Pilot study to compare the effects of a continuous combined hormone replacement therapy (HRT) regimen with an interrupted progestogen regimen administered transdermally, upon the endometrium of postmenopausal women, the incidence of amenorrhoea and relief of menopausal symptoms. METHODS:Fifty-nine postmenop...

journal_title：Maturitas

authors： Cameron ST,Glasier AF,Gebbie A,Dewart H,Baird DT

更新日期：2006-01-10 00:00:00

abstract：OBJECTIVES:Study to compare the effects of tibolone and raloxifene on health-related quality of life, sexuality and vaginal atrophy. METHODS:A double-blind, randomized study was conducted in 308 osteopenic, but otherwise healthy, postmenopausal women (mean age 66 years) who received tibolone 1.25mg/day or raloxifene 6...

journal_title：Maturitas

authors： Nijland EA,Weijmar Schultz WC,Davis SR

更新日期：2007-10-20 00:00:00

abstract：:This study was a cross-sectional survey of mid-aged Thai women with the following aims: to describe their experience of symptoms and attitudes to menopause and to examine the relationships between symptoms, attitudes to menopause, sociodemographic variables and menopausal status. The sample was 268 women aged between ...

journal_title：Maturitas

authors： Punyahotra S,Dennerstein L,Lehert P

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:Participation in regular physical activity is among the most promising and cost effective strategies to reduce physical and cognitive decline and premature death. However, confusion remains about the amount, frequency, and duration of physical activity that is likely to provide maximum benefit as well as the...

journal_title：Maturitas

authors： Anderson D,Seib C,Rasmussen L

更新日期：2014-09-01 00:00:00

abstract：:Most therapy for osteoporosis has been aimed at decreasing bone resorption and is capable of preventing further bone loss. Recently, anabolic steroids have been claimed to cause increased bone mass in osteoporosis, but the mechanism for this effect is not understood. In this study calcium, and calcium with calcitriol,...

journal_title：Maturitas

authors： Need AG,Chatterton BE,Walker CJ,Steurer TA,Horowitz M,Nordin BE

更新日期：1986-12-01 00:00:00

abstract：OBJECTIVES:The purpose of this study was to evaluate endothelium-dependent flow-mediated dilation (FMD) in the brachial artery and the plasma levels of endothelin-1 in postmenopausal women at risk for coronary artery disease before and after treatment with both estradiol and estradiol plus dydrogesterone. METHODS:Sixt...

journal_title：Maturitas

authors： Gambacciani M,Monteleone P,Vitale C,Silvestri A,Fini M,Genazzani AR,Rosano GM

更新日期：2002-10-25 00:00:00

abstract：:The reduction of gonadotrophin levels, urinary calcium and hot flushes in post-menopausal patients by ethinyl oestradiol is shown to be dose dependent, near maximum response being achieved by a dose of 15 micrograms daily. Equivalent ethinyl oestradiol doses to a number of other gonadal hormone preparations have been ...

journal_title：Maturitas

authors： Jones MM,Pearlman B,Marshall DH,Crilly RG,Nordin BE

更新日期：1982-12-01 00:00:00

abstract：OBJECTIVE:To compare clinical characteristics and management of adnexal torsion in postmenopausal patients as compared to premenopausal ones. METHODS:A retrospective 22 year cohort of all cases of surgically verified adnexal torsion in postmenopausal and premenopausal patients, comparing presentation, imaging, surgica...

journal_title：Maturitas

authors： Ganer Herman H,Shalev A,Ginath S,Kerner R,Keidar R,Bar J,Sagiv R

更新日期：2015-05-01 00:00:00

abstract：OBJECTIVES:To study whether dose adjustments in transdermal estradiol gel treatment would result in proportional changes in estradiol bioavailability and concentrations. METHODS:In an open study, 23 healthy postmenopausal women were treated consecutively with 0.5, 1.0 and 1.5 mg estradiol daily as a transdermal gel. E...

journal_title：Maturitas

authors： Järvinen A,Granander M,Laine T,Viitanen A

更新日期：2000-04-28 00:00:00

abstract：:Estrogen is a well-known mitogen in human breast epithelium but the action of progestogen is complex and incompletely understood. During the last years, accumulating data from animal, clinical and observational studies suggest a proliferative effect in breast tissue when progestogen is added to estrogen. Findings in s...

journal_title：Maturitas

authors： Söderqvist G,von Schoultz B

更新日期：2004-09-24 00:00:00

abstract：OBJECTIVE:In this study we aimed to pilot test the hypothesis that in women who are severely bothered by their menopausal complaints, improvement of menopausal symptoms is associated with an improvement in self-perceived work ability. STUDY DESIGN:This retrospective cohort study assessed the work ability of first-time...

journal_title：Maturitas

authors： Geukes M,Anema JR,van Aalst MP,de Menezes RX,Oosterhof H

更新日期：2019-02-01 00:00:00

abstract：OBJECTIVES:Bone mineral density (BMD) and development of osteoporosis are partly determined by genetic factors. The associations between one of suggested candidate, apolipoprotein E (apo E) genotype to bone mineral density (BMD) and bone biochemical markers was studied in 464 subjects recruited from a population-based ...

journal_title：Maturitas

authors： Heikkinen AM,Kröger H,Niskanen L,Komulainen MH,Ryynänen M,Parviainen MT,Tuppurainen MT,Honkanen R,Saarikoski S

更新日期：2000-01-15 00:00:00

abstract：OBJECTIVE:Alterations in sleep quality and metabolism during menopause are improved by menopausal hormone therapy (MHT). The mechanisms mediating these effects remain unclear. Orexin A (OxA) is a neuro-peptide that regulates sleep/wakefulness, food intake and metabolism. This study examined changes in plasma OxA levels...

journal_title：Maturitas

authors： Cintron D,Beckman JP,Bailey KR,Lahr BD,Jayachandran M,Miller VM

更新日期：2017-05-01 00:00:00

abstract：:Fifty postmenopausal women requiring hormone replacement therapy for the treatment of climacteric symptoms were recruited in six centers. All patients received a new combined norethisterone acetate (NETA)/oestradiol (E2)-TTS, (Estragest TTS, Ciba-Geigy Ltd), delivering 0.25 mg NETA and 50 micrograms E2 per day, contin...

journal_title：Maturitas

authors： Oosterbaan HP,van Buuren AH,Schram JH,van Kempen PJ,Ubachs JM,van Leusden HA,Beyer GP

更新日期：1995-04-01 00:00:00

abstract：OBJECTIVES:The study purpose was to evaluate the longitudinal effects, after 3 months and 1-year, of a perimenopausal health education intervention for mid-life women in Taiwan. METHODS:This study was conducted at two hospitals and their neighborhood communities (each included three subgroups, traditional Chinese, gyn...

journal_title：Maturitas

authors： Tsao LI,Su MC,Hsiao PJ,Gau YM,An C,Lin KC

更新日期：2007-07-20 00:00:00

abstract：:The uterine environment is often viewed as a relatively safe haven, being guarded by the placenta which acts as a filter, permitting required materials to enter and unwanted products to be removed. However, this defensive barrier is sometimes breached by potential chemical hazards to which the mother may be subjected....

journal_title：Maturitas

authors： Waring RH,Harris RM,Mitchell SC

更新日期：2016-04-01 00:00:00

abstract：AIMS:Women in the West can now expect to live one third of their life in a postmenopausal state, and consequently in a state of estrogen deficiency. This can have a number of consequences, and many women suffer vasomotor symptoms during the climacteric. Estrogen deficiency can also result in changes to the skin, hair, ...

journal_title：Maturitas

authors： Palacios S

更新日期：1999-11-01 00:00:00

abstract：:Hormone replacement therapy (HRT) in postmenopausal women is associated with a reduction in the risk of developing coronary artery disease (CAD) of about 50%. Women with an elevated risk for CAD appear to benefit most by HRT. The HRT-associated cardiovascular protection may be related to favourable changes in several ...

journal_title：Maturitas

authors： van der Mooren MJ,Mijatovic V,van Baal WM,Stehouwer CD

更新日期：1998-09-20 00:00:00

abstract：OBJECTIVES:To examine the effect of Cimicifuga racemosa (CR BNO 1055) on hot flushes caused by tamoxifen adjuvant therapy in young premenopausal breast cancer survivors. This treatment presents an off-label use of CR BNO 1055. METHODS:Between May 1999 and December 2001, we accrued 136 breast cancer survivors aged 35-5...

journal_title：Maturitas

authors： Hernández Muñoz G,Pluchino S

更新日期：2003-03-14 00:00:00