Abstract:
:The mean plasma anion gap (Na + K + Ca + Mg)--(Cl + HCO3(-) + HPO4(2-) + protein), was significantly higher in post-menopausal women compared with pre-menopausal women (8.04 mEq/l compared with 7.03 mEq/l). This change was due, in part, to an increase in the plasma lactate concentration and to smaller increases in citrate and pyruvate concentrations. There were also changes in bicarbonate and chloride concentrations which suggested an increase pH of approximately 0.02 U. Together, these changes accounted for 46% of the increase in the "anion gap", leaving 54% unexplained. It is suggested that the rise in plasma lactate concentration may be due to mild alkalosis and that this change may account for the rise in plasma urate concentration which also occurs at the menopause.
journal_name
Maturitasjournal_title
Maturitasauthors
Hodgkinson A,Jones MM,Marshall RW,Skerrow SMdoi
10.1016/0378-5122(84)90049-5subject
Has Abstractpub_date
1984-03-01 00:00:00pages
171-6issue
3eissn
0378-5122issn
1873-4111journal_volume
5pub_type
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