Clinical audit of estradiol implant therapy: Long duration of action and implications in non-hysterectomised women.

Abstract:

:We audited the files of 114 postmenopausal women who had been treated with subcutaneous Estrapel (50mg oestradiol implants). Of the 92 women who received more than one implant, the median number of days between implants was 223.5 (range 49-875), with an estimated median time to return to baseline of 311days (range 108-1228). Although oestradiol implants can provide an excellent non-oral treatment option, their prolonged action makes patient selection important, as the implants cannot easily be removed. In women with an intact uterus, the continuation of progestin therapy after cessation of implant therapy is imperative.

journal_name

Maturitas

journal_title

Maturitas

authors

Wheatley S,Bell RJ,Stuckey BG,Robinson PJ,Davis SR

doi

10.1016/j.maturitas.2016.09.008

subject

Has Abstract

pub_date

2016-12-01 00:00:00

pages

84-86

eissn

0378-5122

issn

1873-4111

pii

S0378-5122(16)30225-0

journal_volume

94

pub_type

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