The current state of stem cell therapy for peripheral artery disease.

abstract：PURPOSE OF REVIEW:Monoclonal antibodies that inhibit proprotein convertase subtilisin/kexin type 9 (PCSK9) have emerged as a novel approach to low-density lipoprotein cholesterol (LDL-C) lowering. The potential role of PCSK9 inhibitors in clinical practice will be reviewed. RECENT FINDINGS:Clinical trials have demonst...

journal_title：Current cardiology reports

authors： King P,Nicholls SJ

更新日期：2017-08-01 00:00:00

abstract：:Gut microbiota has been recently established to have a contributory role in the development of cardiometabolic disorders, such as atherosclerosis, obesity, and type 2 diabetes. Growing interest has focused on the modulation of gut microbiota as a therapeutic strategy in cardiovascular diseases and metabolic disorders....

journal_title：Current cardiology reports

authors： Miele L,Giorgio V,Alberelli MA,De Candia E,Gasbarrini A,Grieco A

更新日期：2015-12-01 00:00:00

abstract：:Radiofrequency ablation is a valuable adjunctive therapy to implantable defibrillators in patients with recurrent monomorphic ventricular tachycardia (VT) after myocardial infarction. Episodes of VT are markedly reduced in most patients, and the major complications are less than 5%. Newer approaches allow successful a...

journal_title：Current cardiology reports

authors： Soejima K,Stevenson WG

更新日期：2003-09-01 00:00:00

abstract：:Patients from racial and ethnic minorities experience higher mortality after cardiac surgery compared to white patients, both during the early postoperative phase as well as long term. A number of factors likely explain poor outcomes in black and minority patients, which include differences in biology, comorbid health...

journal_title：Current cardiology reports

authors： Khera R,Vaughan-Sarrazin M,Rosenthal GE,Girotra S

更新日期：2015-05-01 00:00:00

abstract：:Plasminogen activation potential in the blood is controlled by an equilibrium between plasminogen activators, mainly tissue-type plasminogen activator (t-PA), and inhibitors, mainly plasminogen activator inhibitor (PAI)-1. In cardiovascular practice, imbalance of this fibrinolytic potential is encountered primarily in...

journal_title：Current cardiology reports

authors： Juhan-Vague I,Morange P,Christine Alessi M

更新日期：1999-07-01 00:00:00

abstract：:Biventricular pacing (cardiac resynchronization therapy ) has been shown to be a very effective therapy for patients with heart failure and dyssynchrony, with improved survival now shown in a recent trial. Electrical dyssynchrony, usually quantified by the duration of the QRS complex, is distinct from mechanical dyssy...

journal_title：Current cardiology reports

authors： Bilchick KC,Helm RH,Kass DA

更新日期：2007-09-01 00:00:00

abstract：:Cardiovascular mortality continues to be high and events continue to occur in patients taking antiplatelet medications. Aspirin and clopidogrel have become integral parts of management in patients with coronary artery disease and after percutaneous angioplasty. However, the platelet responses to aspirin and clopidogre...

journal_title：Current cardiology reports

authors： Guthikonda S,Lev EI,Kleiman NS

更新日期：2005-07-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review was to synthesize research findings from recently published randomized controlled trials (RCTs) targeting any phase of medication adherence, from initiation to discontinuation, among patients with coronary heart disease (CHD). RECENT FINDINGS:We identified successful strate...

journal_title：Current cardiology reports

authors： Zullig LL,Ramos K,Bosworth HB

更新日期：2017-09-22 00:00:00

abstract：:The heart and kidney interact in terms of hemodynamics and neurohumoral regulatory mechanisms, and this helps to maintain circulatory homeostasis under normal conditions. However, the normal regulatory mechanisms become inappropriate in the setting of congestive heart failure (CHF), and significant renal dysfunction o...

journal_title：Current cardiology reports

authors： Sobotka PA,Krum H,Böhm M,Francis DP,Schlaich MP

更新日期：2012-06-01 00:00:00

abstract：:Lifestyle modification is primary in cardiovascular (CV) disease prevention. A major contribution is the Mediterranean diet (MedDiet), defined by two of seven components. Italian investigators determined a significant decrease in peripheral arterial disease of 56 % for a high score. Multiple specific CV risk factors a...

journal_title：Current cardiology reports

authors： Whayne TF Jr

更新日期：2014-01-01 00:00:00

abstract：:The prevalence of atrial fibrillation increases significantly with age, affecting nearly 10 % of adults greater than 80 years of age. Complications from atrial fibrillation, including stroke, also increase with age. Medical therapy includes anticoagulation, ventricular rate control, and if symptoms persist, maintenanc...

journal_title：Current cardiology reports

authors： Stepanyan G,Gerstenfeld EP

更新日期：2013-10-01 00:00:00

abstract：PURPOSE OF REVIEW:There is a broad spectrum of coronary artery anomalies that cardiologists may encounter either incidentally or during evaluation for cardiac symptoms. These anomalies include anomalous coronary arteries arising from the opposite sinus of Valsalva (ACAOS), coronary fistulae, and coronary artery aneurys...

journal_title：Current cardiology reports

authors： Kochar A,Kiefer T

更新日期：2017-05-01 00:00:00

abstract：:Recent advances in clinical cardiac SPECT instrumentation are reviewed from a systems perspective. New hardware technologies include pixelated scintillator and semiconductor detector elements; photodetectors such as position-sensitive photomultiplier tubes (PSPMT), avalanche photodiodes (APD) and silicon photomultipli...

journal_title：Current cardiology reports

authors： Smith MF

更新日期：2013-08-01 00:00:00

abstract：:Basic and animal research implicate inflammatory mechanisms in the pathogenesis and progression of atherosclerosis, plaque rupture, thrombosis, and stroke. Inflammatory biomarkers, particularly high-sensitivity C-reactive protein and lipoprotein-associated phospholipase A2, have been identified as potential predictors...

journal_title：Current cardiology reports

authors： Elkind MS

更新日期：2009-01-01 00:00:00

abstract：:The scientific selection of antithrombotic therapy has been dominated by group-based interpretation of data in the form of probability-based statistics in evidence-based medicine. Because the data in large randomized trials are grouped and averaged, the relationship to initial conditions of the patient is lost. There ...

journal_title：Current cardiology reports

authors： Helgason CM

更新日期：2003-03-01 00:00:00

abstract：:The Fontan operation has been nothing short of revolutionary in its influence on the modern management of patients born with functionally univentricular hearts. The vast majority of these individuals are now surviving well into adulthood. In the 45 years since its introduction, however, there has been increasing recog...

journal_title：Current cardiology reports

authors： Elder RW,Wu FM

更新日期：2016-05-01 00:00:00

abstract：:Chronic total occlusion (CTO) represents one of the most challenging lesion subsets faced by the interventional cardiologist. CTO is a common problem, being present in more than 30% of patients undergoing coronary angiography. Over the past 10 years, the success rate of recanalization has increased from approximately ...

journal_title：Current cardiology reports

authors： Genereux P,Dangas G

更新日期：2010-09-01 00:00:00

abstract：:Cardiac resynchronization therapy has become part of the treatment strategy for advanced, symptomatic heart failure, but newly published trials show that more patients than previously realized may benefit from this therapy, including those with mild heart failure symptoms. The REVERSE and MADIT-CRT trials showed that ...

journal_title：Current cardiology reports

authors： Reynolds CR,Gold MR

更新日期：2010-09-01 00:00:00

abstract：PURPOSE OF REVIEW:An examination of the current ACC/AHA and ESC/EAS Guidelines on the management of dyslipidemias for common ground and differences. RECENT FINDINGS:There is much common ground. Both note that ASCVD is, in most people, the product of a number of risk factors, notably tobacco exposure, hyperlipidemia, h...

journal_title：Current cardiology reports

authors： Graham IM,Catapano AL

更新日期：2017-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Coronary artery bypass grafting is a preferred strategy for complete coronary revascularization in patients who have multi-vessel coronary artery disease, left ventricular dysfunction, and/or diabetes. Both arterial (internal thoracic artery/radial artery) and venous grafts are utilized to bypass the ...

journal_title：Current cardiology reports

authors： Virk HUH,Lakhter V,Ahmed M,O' Murchu B,Chatterjee S

更新日期：2019-03-22 00:00:00

abstract：PURPOSE OF REVIEW:To summarize lifestyle interventions including pharmacological and non-pharmacological methods targeting modifiable risk factors and their impact on the future cardiovascular events in patients who have suffered transient ischemic attack (TIA) and/or ischemic stroke (IS). RECENT FINDINGS:The latest r...

journal_title：Current cardiology reports

authors： Vellipuram AR,Rodriguez G,Rawla P,Maud A,Cruz-Flores S,Khatri R

更新日期：2019-04-22 00:00:00

abstract：:The decline in the use of sodium channel blockers has led to an expanding use of b-blockers and complex class III agents such as sotalol and amiodarone for controlling cardiac arrhythmias. Success with these agents in the context of their side effects has spurred the development of compounds with simpler ion channel-b...

journal_title：Current cardiology reports

authors： Singh BN,Sarma JS

更新日期：2001-07-01 00:00:00

abstract：:Sudden cardiac death (SCD) is the leading cause of death in the United States. Although SCD occurs most commonly in patients with established heart disease, SCD can also be the initial manifestation of cardiovascular disease. Efforts to reduce the incidence of SCD include aggressive treatment of heart disease and its ...

journal_title：Current cardiology reports

authors： Ganz LI

更新日期：2004-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Congenital heart disease is the most common birth defect and acquired heart disease is the leading cause of death in adults. Understanding the mechanisms that drive cardiomyocyte proliferation and differentiation has the potential to advance the understanding and potentially the treatment of different...

journal_title：Current cardiology reports

authors： Yester JW,Kühn B

更新日期：2017-02-01 00:00:00

abstract：:The management of chronic stable angina has undergone considerable evolution over the past two decades. This article highlights the need for a comprehensive approach to management that includes carefully identifying cardiac risk factors, using therapeutic lifestyle interventions, aggressive, multifaceted medical thera...

journal_title：Current cardiology reports

authors： Eid F,Boden WE

更新日期：2008-07-01 00:00:00

abstract：:Transcatheter aortic valve replacement (TAVR) has become an alternative to surgical intervention for symptomatic or severe aortic valve stenosis in patients with high surgical risk. Successful TAVR requires a multimodality imaging approach for appropriate patient selection and prosthesis sizing. Here, we describe indi...

journal_title：Current cardiology reports

authors： Caruso D,Rosenberg RD,De Cecco CN,Mangold S,Wichmann JL,Varga-Szemes A,Steinberg DH,Laghi A,Schoepf UJ

更新日期：2016-02-01 00:00:00

abstract：:Aortic stenosis is a common valvular abnormality. Surgical valve replacement is the standard of care for symptomatic patients with severe aortic stenosis and is appropriate for certain asymptomatic patients. Statin therapy may slow progression of the disease. Contrary to conventional wisdom, vasodilator therapy may in...

journal_title：Current cardiology reports

authors： Botkin NF,Aurigemma GP

更新日期：2004-03-01 00:00:00

abstract：PURPOSE OF REVIEW:To analyze the current state of the art of functional mitral regurgitation (FMR) treatment. RECENT FINDINGS:The first-line treatment of severe FMR consists of guideline medical therapy (GMT) and resynchronization therapy when indicated; the impact of new medical therapies like sacubitril/valsartan ne...

journal_title：Current cardiology reports

authors： Fabris E,De Luca A,Vitrella G,Stolfo D,Masè M,Korcova R,Merlo M,Rakar S,Van't Hof AWJ,Kedhi E,Perkan A,Sinagra G

更新日期：2019-11-16 00:00:00

abstract：:Therapy to prevent deep venous thrombosis (DVT) and pulmonary embolism remains essential for inpatients, despite short periods of bedrest and hospitalization. Although most available data pertain to surgical patients, subgroups of medical patients are at moderate, high, and very high risk for DVT. These include patien...

journal_title：Current cardiology reports

authors： Shively BK

更新日期：2001-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Angiotensin-converting enzyme inhibitors and angiotensin receptor blockers are commonly used anti-hypertensive medications in a number of clinical settings. They are often used interchangeably, but we pose the provocative question as to whether they should be. We review the literature to evaluate for ...

journal_title：Current cardiology reports

authors： Turner JM,Kodali R

更新日期：2020-07-09 00:00:00