Resistance to antiplatelet therapy.

abstract：:On page 2 of the original publication, in the section on TTR Silencers dosing of patisiran in the APOLLO study was stated as being given every 3 months; this is inaccurate as patisiran was dosed every 3 weeks in the APOLLO study. ...

journal_title：Current cardiology reports

authors： Hough A,Wearden J,de Almeida K,Kaiser S

更新日期：2020-09-28 00:00:00

abstract：:Although clinical evidence indicates that many of the electrophysiologic and functional changes associated with atrial fibrillation (AF) can be reversed by maintaining normal sinus rhythm (NSR), a series of large-scale randomized trials failed to demonstrate that this strategy provides a survival advantage. These stud...

journal_title：Current cardiology reports

authors： Zimetbaum P

更新日期：2006-09-01 00:00:00

abstract：PURPOSE OF REVIEW:To analyze the current state of the art of functional mitral regurgitation (FMR) treatment. RECENT FINDINGS:The first-line treatment of severe FMR consists of guideline medical therapy (GMT) and resynchronization therapy when indicated; the impact of new medical therapies like sacubitril/valsartan ne...

journal_title：Current cardiology reports

authors： Fabris E,De Luca A,Vitrella G,Stolfo D,Masè M,Korcova R,Merlo M,Rakar S,Van't Hof AWJ,Kedhi E,Perkan A,Sinagra G

更新日期：2019-11-16 00:00:00

abstract：:Medical management of patients with atrial fibrillation (AF) at high risk for stroke is limited by problems of imperfect tools for assessment of thromboembolism and bleeding risks. Improved instruments, such as the CHA₂DS₂VASc and HAS-BLED risk stratification scores, have been incorporated into European practice guide...

journal_title：Current cardiology reports

authors： Broukhim M,Halperin JL

更新日期：2011-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Comprehensive discussion of alternative techniques in imaging coronary artery anomalies (CAAs) in different diagnostic scenarios. RECENT FINDINGS:At primary screening, intramural course essentially correlates with stenosis and clinical repercussion in some types of CAAs. Potential clinical aims in im...

journal_title：Current cardiology reports

authors： Angelini P

更新日期：2019-07-29 00:00:00

abstract：:Cardiac implantable electronic device (CIED) infections are complex medical problems that are increasingly encountered. They are associated with significant morbidity and mortality with tremendous economic cost. The current review will emphasize the prevention, diagnosis, and treatment of this clinical entity using th...

journal_title：Current cardiology reports

authors： Leung S,Danik S

更新日期：2016-06-01 00:00:00

abstract：:Although advanced heart failure has been considered the main indication for heart transplantation, the increasing number of candidates and shortage of organs for transplantation, with accumulating waiting lists, has originated another look into more conventional surgery, previously considered of prohibitive risk. In f...

journal_title：Current cardiology reports

authors： Ferrão de Oliveira J,Antunes MJ

更新日期：2004-05-01 00:00:00

abstract：:The feasibility and safety of transradial coronary intervention was demonstrated soon after the description of the transfemoral approach, despite which the use of the femoral artery still dominates in acute coronary syndrome intervention. The advantages of using the radial artery are virtual elimination of access site...

journal_title：Current cardiology reports

authors： Routledge H,Sastry S

更新日期：2015-12-01 00:00:00

abstract：:Heart failure management is complex and costly. Genetic variations that alter drug absorption, metabolism, and receptor-ligand interactions have the potential to modify drug response and safety. Evidence shows that genetic factors interact with numerous heart failure medications, including vasodilators, beta blockers,...

journal_title：Current cardiology reports

authors： Lowes BD,Buttrick PM

更新日期：2008-05-01 00:00:00

abstract：:Fifty thousand Americans suffer an intracerebral hemorrhage (ICH) annually, one third of whom die as a result. Poorly controlled hypertension is the most important risk factor for ICH. Over time it results in pathologic changes to small intracranial vessels, leading to their rupture. All stroke patients, including tho...

journal_title：Current cardiology reports

authors： Tuhrim S

更新日期：2002-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Interventional cardiology and in particular the field of renal denervation is subject to constant change. This review provides an up to date overview of renal denervation trials and an outlook on what to expect in the future. RECENT FINDINGS:After the sham-controlled SYMPLICITY HTN-3 trial dampened t...

journal_title：Current cardiology reports

authors： Lauder L,Wolf MA,Scholz SS,Hohl M,Mahfoud F,Böhm M

更新日期：2019-07-05 00:00:00

abstract：:Recurrent pericarditis is one of the most troublesome complications of pericarditis occurring in about one third of patients with a previous attack of pericarditis. The pathogenesis is presumed to be autoimmune and/or autoinflammatory in most cases. The mainstay of therapy for recurrences is physical restriction and a...

journal_title：Current cardiology reports

authors： Imazio M,Adler Y,Charron P

更新日期：2016-06-01 00:00:00

abstract：PURPOSE OF REVIEW:To establish the actual role of CT in the growing field of transcatheter valve interventions (THV). RECENT FINDINGS:The development of empirical CT measurements, which are linked with outcomes. CT is a reliable technique for assessing risk and planning transcatheter valve interventions for mitral and...

journal_title：Current cardiology reports

authors： Godoy M,Mugharbil A,Anastasius M,Leipsic J

更新日期：2019-11-25 00:00:00

abstract：:Basic and animal research implicate inflammatory mechanisms in the pathogenesis and progression of atherosclerosis, plaque rupture, thrombosis, and stroke. Inflammatory biomarkers, particularly high-sensitivity C-reactive protein and lipoprotein-associated phospholipase A2, have been identified as potential predictors...

journal_title：Current cardiology reports

authors： Elkind MS

更新日期：2009-01-01 00:00:00

abstract：:Patients with pre-diabetes have a tenfold higher risk of developing Type 2 DM and a twofold higher risk of developing coronary heart disease compared to non-diabetics. Interventions targeted at those in an early stage of impaired glucose metabolism can delay or prevent diabetes. Effects of these interventions on cardi...

journal_title：Current cardiology reports

authors： Popp Switzer M,Elhanafi S,San Juan ZT

更新日期：2015-03-01 00:00:00

abstract：:Heart failure is a major public health concern that is frequently complicated by ventricular arrhythmias. Sustained ventricular tachycardia is associated with an increased risk for progressive heart failure and sudden death. We summarize the current management strategies for ventricular tachycardia in heart failure pa...

journal_title：Current cardiology reports

authors： Fong MW,Grazette L,Cesario D,Cao M,Saxon L

更新日期：2011-06-01 00:00:00

abstract：:Understanding the genetic risk factors for stroke is an essential step to decipher the underlying mechanisms, facilitate the identification of novel therapeutic targets, and optimize the design of prevention strategies. A very small proportion of strokes are attributable to monogenic conditions, the vast majority bein...

journal_title：Current cardiology reports

authors： Chauhan G,Debette S

更新日期：2016-12-01 00:00:00

abstract：:Controlled clinical trials, performed in more than 13,000 patients, have consistently shown the beneficial effects of long-term beta-blocker therapy in patients with chronic heart failure. However, it is not clear whether this is a class effect or if it is specific only for some agents. Beneficial effects on the progn...

journal_title：Current cardiology reports

authors： Metra M,Nodari S,Boldi E,Dei Cas L

更新日期：2000-05-01 00:00:00

abstract：:Shared decision-making, central to evidence-based medicine and good patient care, begins and ends with the patient. It is the process by which a clinician and a patient jointly make a health decision after discussing options, potential benefits and harms, and considering the patient's values and preferences. Patient e...

journal_title：Current cardiology reports

authors： Kambhampati S,Ashvetiya T,Stone NJ,Blumenthal RS,Martin SS

更新日期：2016-05-01 00:00:00

abstract：:Therapy to prevent deep venous thrombosis (DVT) and pulmonary embolism remains essential for inpatients, despite short periods of bedrest and hospitalization. Although most available data pertain to surgical patients, subgroups of medical patients are at moderate, high, and very high risk for DVT. These include patien...

journal_title：Current cardiology reports

authors： Shively BK

更新日期：2001-01-01 00:00:00

abstract：:Gut microbiota has been recently established to have a contributory role in the development of cardiometabolic disorders, such as atherosclerosis, obesity, and type 2 diabetes. Growing interest has focused on the modulation of gut microbiota as a therapeutic strategy in cardiovascular diseases and metabolic disorders....

journal_title：Current cardiology reports

authors： Miele L,Giorgio V,Alberelli MA,De Candia E,Gasbarrini A,Grieco A

更新日期：2015-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The review is focused on "digital health", which means advanced analytics based on multi-modal data. The "Health Care Internet of Things", which uses sensors, apps, and remote monitoring could provide continuous clinical information in the cloud that enables clinicians to access the information they n...

journal_title：Current cardiology reports

authors： Mazzanti M,Shirka E,Gjergo H,Hasimi E

更新日期：2018-05-10 00:00:00

abstract：:The Fontan operation has been nothing short of revolutionary in its influence on the modern management of patients born with functionally univentricular hearts. The vast majority of these individuals are now surviving well into adulthood. In the 45 years since its introduction, however, there has been increasing recog...

journal_title：Current cardiology reports

authors： Elder RW,Wu FM

更新日期：2016-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Innovation for transcatheter aortic valve replacement (TAVR) has transformed a medically complex treatment into a standardized procedure. While Edwards SAPIEN and Medtronic CoreValve occupy the market for TAVR in the United States (US), additional valve systems are being developed. The Boston Scientif...

journal_title：Current cardiology reports

authors： Seigerman ME,Nathan A,Anwaruddin S

更新日期：2019-11-25 00:00:00

abstract：:Atherosclerosis is the proximate cause of arterial thrombosis, leading to acute occlusive cardiovascular syndromes. Thrombosis in atherosclerosis usually results from rupture of the fibrous cap of atherosclerotic plaques with a smaller proportion resulting from superficial endothelial erosion. Ruptured plaques are oft...

journal_title：Current cardiology reports

authors： Shah PK

更新日期：2014-12-01 00:00:00

abstract：:Although overall stroke incidence has been declining in developed countries, there is evidence that stroke in the young is increasing. Increasing incidence may be particularly pronounced among minorities in whom historically a higher burden of stroke has been reported. Compared with older adults, time spent with disab...

journal_title：Current cardiology reports

authors： Sultan S,Elkind MS

更新日期：2013-12-01 00:00:00

abstract：:Conventional algorithms and noninvasive imaging tests for the identification of stable, hemodynamically significant coronary artery disease offer little insight into the detection of potentially vulnerable and inflamed coronary plaques, those most likely to rupture and cause acute coronary syndromes. Positron emission...

journal_title：Current cardiology reports

authors： Rogers IS,Tawakol A

更新日期：2011-04-01 00:00:00

abstract：:Leukocytes play a critical role in both the initial steps of atherogenesis and the late events of plaque instability and thrombosis. Leukocyte-endothelial cell adhesion molecules (CAMs) modulate the interaction between circulating leukocytes and the vessel wall. Levels of soluble CAMs are increased in patients with dy...

journal_title：Current cardiology reports

authors： Ballantyne CM,Abe Y

更新日期：1999-09-01 00:00:00

abstract：:Imaging with radionuclides has historically played an important role in detection of cardiovascular disease as well as in risk stratification and prognostication. With the growth of molecular biology have come new therapeutic interventions and the requirement for new diagnostic imaging approaches. Noninvasive targeted...

journal_title：Current cardiology reports

authors： Dobrucki LW,Sinusas AJ

更新日期：2005-03-01 00:00:00

abstract：:Diastolic dysfunction in patients with hypertension may present as asymptomatic findings on noninvasive testing, or as fulminant pulmonary edema, despite normal left ventricular systolic function. Up to 40% of hypertensive patients presenting with clinical signs of congestive heart failure have normal systolic left ve...

journal_title：Current cardiology reports

authors： Phillips RA,Diamond JA

更新日期：2001-11-01 00:00:00