Genetic determinants of drug response in heart failure.

abstract：:A natural extension of current imaging paradigms for diagnosing coronary artery disease may well be the integration of CT with myocardial perfusion single-photon CT (SPECT). Although there is a wealth of clinical information regarding the utility of SPECT, the value of CT in the cardiology arena has only recently been...

journal_title：Current cardiology reports

authors： Mahmarian JJ

更新日期：2007-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Cardiac troponin (cTn) plays an essential role for assessment of outcome in acute coronary syndrome (ACS). However, the prognostic value of cTn is not absolute. In this mini-review, we summarize the evidence on the utility of established biomarkers of left-ventricular dysfunction, hemodynamic stress, ...

journal_title：Current cardiology reports

authors： Eggers KM,Lindahl B

更新日期：2017-04-01 00:00:00

abstract：:There has been considerable attention in recent years to the intriguing hypothesis that coronary heart disease and other atherosclerotic diseases may be caused by infection with pathogens such as Chlamydia pneumoniae, Helicobacter pylori, and cytomegalovirus. Supporting this hypothesis are studies that localize bacter...

journal_title：Current cardiology reports

authors： O'Donnell CJ,Levy D

更新日期：2000-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Congenital heart disease is the most common birth defect and acquired heart disease is the leading cause of death in adults. Understanding the mechanisms that drive cardiomyocyte proliferation and differentiation has the potential to advance the understanding and potentially the treatment of different...

journal_title：Current cardiology reports

authors： Yester JW,Kühn B

更新日期：2017-02-01 00:00:00

abstract：:Significant progress in research has been made in the areas of sex-specific aspects of cardiovascular disease. Despite these advances, coronary artery disease (CAD) is the leading cause of death of women in the Western world. Over the past decade, the focused research on women at risk for ischemic heart disease has he...

journal_title：Current cardiology reports

authors： Phillips LM,Mieres JH

更新日期：2010-03-01 00:00:00

abstract：:Understanding the genetic risk factors for stroke is an essential step to decipher the underlying mechanisms, facilitate the identification of novel therapeutic targets, and optimize the design of prevention strategies. A very small proportion of strokes are attributable to monogenic conditions, the vast majority bein...

journal_title：Current cardiology reports

authors： Chauhan G,Debette S

更新日期：2016-12-01 00:00:00

abstract：:The risk of stroke associated with carotid artery stenosis can be reduced with carotid endarterectomy or carotid artery stenting in carefully selected patients. While surgery has been the traditional treatment there have been many trials comparing carotid endarterectomy with carotid artery stenting, and stenting has s...

journal_title：Current cardiology reports

authors： Buschur M,Gurm HS

更新日期：2012-02-05 00:00:00

abstract：:Aldosterone is the principal circulating mineralocorticoid in humans, and aldosterone synthesis normally occurs in the face of volume depletion and renin stimulation. In primary and secondary aldosteronism, aldosterone synthesis continues despite volume expansion and causes hypertension. Other steroid hormones that ar...

journal_title：Current cardiology reports

authors： Auchus RJ

更新日期：2005-11-01 00:00:00

abstract：:Primary aldosteronism with a prevalence of 8 % of hypertension and 20 % of pharmacologically resistant hypertension is the most common secondary cause of hypertension. Yet, the diagnosis is missed in the vast majority of patients. Current clinical practice guidelines recommend screening for primary aldosteronism in pa...

journal_title：Current cardiology reports

authors： Carey RM

更新日期：2016-10-01 00:00:00

abstract：:Although overall stroke incidence has been declining in developed countries, there is evidence that stroke in the young is increasing. Increasing incidence may be particularly pronounced among minorities in whom historically a higher burden of stroke has been reported. Compared with older adults, time spent with disab...

journal_title：Current cardiology reports

authors： Sultan S,Elkind MS

更新日期：2013-12-01 00:00:00

abstract：:There are a number of limitations associated with conventional mapping for ablation of ventricular tachycardia (VT) in ischemic heart disease, such as the high recurrence rates after initially successful ablation. The development of a noncontact mapping system capable of producing high-resolution isopotential maps of ...

journal_title：Current cardiology reports

authors： Chow AW,Schilling RJ,Peters NS,Davies DW

更新日期：2000-11-01 00:00:00

abstract：PURPOSE OF REVIEW:The goal was to evaluate published data on the incidence, diagnosis, and management of symptomatic combined mitral and aortic valvular disease. Furthermore, to identify the role of treatment using contemporary transcatheter techniques. RECENT FINDINGS:Up to a quarter of symptomatic adult valvular dis...

journal_title：Current cardiology reports

authors： De Palma R,O'Sullivan CJ,Settergren M

更新日期：2019-09-13 00:00:00

abstract：PURPOSE OF REVIEW:To review the clinical evidence on the use of percutaneous coronary intervention (PCI) revascularization options in left main (LM) disease in comparison with coronary artery bypass graft (CABG). Coronary artery disease (CAD) involving the LM is associated with high morbidity and mortality. Though CABG...

journal_title：Current cardiology reports

authors： Nagarajarao HS,Ojha CP,Mulukutla V,Ibrahim A,Mares AC,Paul TK

更新日期：2020-02-08 00:00:00

abstract：:Cardiovascular mortality continues to be high and events continue to occur in patients taking antiplatelet medications. Aspirin and clopidogrel have become integral parts of management in patients with coronary artery disease and after percutaneous angioplasty. However, the platelet responses to aspirin and clopidogre...

journal_title：Current cardiology reports

authors： Guthikonda S,Lev EI,Kleiman NS

更新日期：2005-07-01 00:00:00

abstract：:Since 1971, the Fontan operation has been performed for the repair of single-ventricle physiology. This ingenious operation commits a single ventricle to the systemic circulation and takes advantage of cardiovascular and respiratory physiology to propel deoxygenated blood to the lungs, thus minimizing right-to-left sh...

journal_title：Current cardiology reports

authors： Aboulhosn J,Child JS

更新日期：2007-07-01 00:00:00

abstract：:Thrombolytic therapy aims to achieve rapid and sustained infarct-related artery patency, although this results in a procoagulant state. Heparin has limitations as an antithrombin agent, which has led to clinical investigation of alternative agents. Direct thrombin inhibitors, as adjuncts to thrombolytic therapy, have ...

journal_title：Current cardiology reports

authors： French JK,White HD

更新日期：1999-09-01 00:00:00

abstract：:While pulmonary arterial hypertension is a disease primarily affecting the pulmonary vasculature, the right ventricle plays an integral part in the disease process. Although widely used, two-dimensional echocardiography is limited in visualizing the right ventricle and, therefore, assessment of its structure and funct...

journal_title：Current cardiology reports

authors： Freed BH,Patel AR,Lang RM

更新日期：2012-06-01 00:00:00

abstract：PURPOSE OF REVIEW:To create awareness for the devastating influence of high cholesterol in familial hypercholesterolaemia (FH) on vessel walls. Persons with high LDL-C and a known mutation associated with FH have a 22-fold increase in CVD compared with those with a normal LDL-C and no genetic mutation. If the awareness...

journal_title：Current cardiology reports

authors： Wiegman A

更新日期：2018-08-09 00:00:00

abstract：:Imaging with radionuclides has historically played an important role in detection of cardiovascular disease as well as in risk stratification and prognostication. With the growth of molecular biology have come new therapeutic interventions and the requirement for new diagnostic imaging approaches. Noninvasive targeted...

journal_title：Current cardiology reports

authors： Dobrucki LW,Sinusas AJ

更新日期：2005-03-01 00:00:00

abstract：:Implantable cardioverter-defibrillators (ICDs) significantly reduce mortality in patients with depressed left ventricular ejection fraction (LVEF) and heart failure (HF). However, shortcomings of LVEF to accurately identify those at greatest risk of ventricular tachyarrhythmias have led to the pursuit of alternative m...

journal_title：Current cardiology reports

authors： Klein T,Dilsizian V,Cao Q,Chen W,Dickfeld TM

更新日期：2013-05-01 00:00:00

abstract：:Four non-communicable diseases-cardiovascular disease, chronic respiratory disease, diabetes mellitus, and cancer-account for over 60 % of all deaths globally. In recognition of this significant epidemic, the United Nations set forth a target of reducing the four major NCDs by 25 % by 2025. Cardiovascular disease alon...

journal_title：Current cardiology reports

authors： Dugani S,Gaziano TA

更新日期：2016-01-01 00:00:00

abstract：:Diabetic patients who present with an acute coronary syndrome (ACS) have a particularly adverse prognosis, largely contributed by increased platelet reactivity and higher burden of disease severity. Diabetic patients with ACS derive a greater benefit from established therapies, particularly platelet-inhibiting therapi...

journal_title：Current cardiology reports

authors： Amin AP,Marso SP

更新日期：2010-07-01 00:00:00

abstract：:True aneurysms of the pulmonary artery are rare, and are most often due to pulmonary hypertension arising from congenital heart defects. We report the case of a 40-year-old man with an uncorrected patent ductus arteriosus who presented with pulmonary infarction and pneumonia, and subsequently died of cardiac arrest. A...

journal_title：Current cardiology reports

authors： Khush KK,Randhawa R,Israel E

更新日期：2005-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Magnetic resonance imaging (MRI) has enabled non-invasive myocardial tissue characterization in a wide range of cardiovascular diseases by quantifying several tissue specific parameters such as T1, T2, and T2* relaxation times. Simultaneous assessment of these parameters has recently gained interest t...

journal_title：Current cardiology reports

authors： Cruz G,Jaubert O,Botnar RM,Prieto C

更新日期：2019-07-27 00:00:00

abstract：PURPOSE OF REVIEW:Acute pulmonary embolism (PE) is a common condition associated with high morbidity and mortality. Prior studies have evaluated the role of systemic fibrinolysis and catheter-directed therapy (CDT) in the management of PE. In this review, we examine current data on risk stratification and the appropria...

journal_title：Current cardiology reports

authors： Kosova EC,Desai KR,Schimmel DR

更新日期：2017-06-01 00:00:00

abstract：:Hypertension in children and adolescents is becoming a greater problem in the developed world. Although traditionally thought of as usually secondary to renal, vascular, or endocrine causes, primary hypertension is becoming the most common form seen in childhood. This changing epidemiology is related to the recent obe...

journal_title：Current cardiology reports

authors： Samuels J,Bell C,Samuel J,Swinford R

更新日期：2015-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Interventional cardiology and in particular the field of renal denervation is subject to constant change. This review provides an up to date overview of renal denervation trials and an outlook on what to expect in the future. RECENT FINDINGS:After the sham-controlled SYMPLICITY HTN-3 trial dampened t...

journal_title：Current cardiology reports

authors： Lauder L,Wolf MA,Scholz SS,Hohl M,Mahfoud F,Böhm M

更新日期：2019-07-05 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review was to synthesize research findings from recently published randomized controlled trials (RCTs) targeting any phase of medication adherence, from initiation to discontinuation, among patients with coronary heart disease (CHD). RECENT FINDINGS:We identified successful strate...

journal_title：Current cardiology reports

authors： Zullig LL,Ramos K,Bosworth HB

更新日期：2017-09-22 00:00:00

abstract：:It has been known for many decades that multiple abnormalities of the autonomic nervous system (ANS) are present in heart failure (HF). Moreover, many of the effective therapies currently used to treat HF have either direct or indirect effects on the ANS. While therapies that block over-activity of the sympathetic ner...

journal_title：Current cardiology reports

authors： Dunlap ME,Bhardwaj A,Hauptman PJ

更新日期：2015-11-01 00:00:00

abstract：:Exercise training is beneficial in healthy adults as well as patients with acquired cardiovascular disease such as coronary artery disease and heart failure. While a reduced exercise capacity is common in adults with congenital heart disease, it is not clear if these patients stand to benefit from exercise training or...

journal_title：Current cardiology reports

authors： Tutarel O,Gabriel H,Diller GP

更新日期：2013-11-01 00:00:00