Direct thrombin inhibitors as adjuncts to thrombolytic therapy.

abstract：:Aldosterone is the principal circulating mineralocorticoid in humans, and aldosterone synthesis normally occurs in the face of volume depletion and renin stimulation. In primary and secondary aldosteronism, aldosterone synthesis continues despite volume expansion and causes hypertension. Other steroid hormones that ar...

journal_title：Current cardiology reports

authors： Auchus RJ

更新日期：2005-11-01 00:00:00

abstract：:Synthesized as an antianginal compound 40 years ago, amiodarone has emerged as a uniquely effective antiarrhythmic compound in recent years. It has numerous properties, the most prominent being the ability to lengthen repolarization in the atria and ventricles associated with bradycardia without the significant potent...

journal_title：Current cardiology reports

authors： Singh BN

更新日期：2006-09-01 00:00:00

abstract：:Congestive heart failure increasingly contributes to the overall morbidity and mortality associated with cardiovascular disease. Although significant advances in therapies allow patients to feel better and have improved functional status and survival, not all patients respond equally to these therapies. Moreover, for ...

journal_title：Current cardiology reports

authors： Chen GP,Caldwell JH

更新日期：2009-03-01 00:00:00

abstract：:There are a number of limitations associated with conventional mapping for ablation of ventricular tachycardia (VT) in ischemic heart disease, such as the high recurrence rates after initially successful ablation. The development of a noncontact mapping system capable of producing high-resolution isopotential maps of ...

journal_title：Current cardiology reports

authors： Chow AW,Schilling RJ,Peters NS,Davies DW

更新日期：2000-11-01 00:00:00

abstract：PURPOSE OF REVIEW:This study aims to describe the current state of telestroke clinical applications and policies, in addition to key technical and operational aspects of the telemedicine practice. RECENT FINDINGS:Delivery of telestroke services for neurovascular care expanded from the intravenous alteplase decision an...

journal_title：Current cardiology reports

authors： Dumitrascu OM,Demaerschalk BM

更新日期：2017-09-01 00:00:00

abstract：:Aortic stenosis is a common valvular abnormality. Surgical valve replacement is the standard of care for symptomatic patients with severe aortic stenosis and is appropriate for certain asymptomatic patients. Statin therapy may slow progression of the disease. Contrary to conventional wisdom, vasodilator therapy may in...

journal_title：Current cardiology reports

authors： Botkin NF,Aurigemma GP

更新日期：2004-03-01 00:00:00

abstract：:Medical management of patients with atrial fibrillation (AF) at high risk for stroke is limited by problems of imperfect tools for assessment of thromboembolism and bleeding risks. Improved instruments, such as the CHA₂DS₂VASc and HAS-BLED risk stratification scores, have been incorporated into European practice guide...

journal_title：Current cardiology reports

authors： Broukhim M,Halperin JL

更新日期：2011-02-01 00:00:00

abstract：:The article title in the original publication contains a mistake. ...

journal_title：Current cardiology reports

authors： Edelson JB,Genuardi MV,Santangeli P,Birati EY

更新日期：2020-09-08 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review was to synthesize research findings from recently published randomized controlled trials (RCTs) targeting any phase of medication adherence, from initiation to discontinuation, among patients with coronary heart disease (CHD). RECENT FINDINGS:We identified successful strate...

journal_title：Current cardiology reports

authors： Zullig LL,Ramos K,Bosworth HB

更新日期：2017-09-22 00:00:00

abstract：:Understanding the genetic risk factors for stroke is an essential step to decipher the underlying mechanisms, facilitate the identification of novel therapeutic targets, and optimize the design of prevention strategies. A very small proportion of strokes are attributable to monogenic conditions, the vast majority bein...

journal_title：Current cardiology reports

authors： Chauhan G,Debette S

更新日期：2016-12-01 00:00:00

abstract：:Aortic stenosis affects many people worldwide with a significant impact on morbidity and mortality with uncorrected, symptomatic aortic valve stenosis carrying mortality of 50% at one year. Degenerative calcific pathology, the most common cause of aortic stenosis, increases in prevalence with age; estimated prevalence...

journal_title：Current cardiology reports

authors： Halim SA,Kiefer TL,Hughes GC,Hurwitz LM,Harrison JK

更新日期：2013-06-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of low-density lipoprotein-cholesterol (LDL-C) lowering therapies is to safely achieve a consistent and long-term reduction in exposure of the vasculature to atherogenic lipoproteins in order to reduce the risk of atherosclerotic cardiovascular (CV) disease and the associated CV events, such a...

journal_title：Current cardiology reports

authors： Sinning D,Landmesser U

更新日期：2020-10-21 00:00:00

abstract：PURPOSE:This paper reviews the double-kiss crush (DK crush) technique in coronary artery bifurcation lesions. The technical aspects of the procedure and the clinical data supporting its use are summarized. RECENT FINDINGS:Randomized studies support the adoption of DK technique in complex bifurcation lesions for both l...

journal_title：Current cardiology reports

authors： Lynn BS,Hermiller JB

更新日期：2018-09-01 00:00:00

abstract：:Cardiovascular mortality continues to be high and events continue to occur in patients taking antiplatelet medications. Aspirin and clopidogrel have become integral parts of management in patients with coronary artery disease and after percutaneous angioplasty. However, the platelet responses to aspirin and clopidogre...

journal_title：Current cardiology reports

authors： Guthikonda S,Lev EI,Kleiman NS

更新日期：2005-07-01 00:00:00

abstract：PURPOSE OF REVIEW:This review provides an update on rheumatic mitral stenosis. Acute rheumatic fever (RF), the sequela of group A β-hemolytic streptococcal infection, is the major etiology for mitral stenosis (MS). RECENT FINDINGS:While the incidence of acute RF in the Western world had substantially declined over the...

journal_title：Current cardiology reports

authors： Wunderlich NC,Dalvi B,Ho SY,Küx H,Siegel RJ

更新日期：2019-02-28 00:00:00

abstract：:Angiotensin-converting enzyme (ACE) inhibitors have become the cornerstone of therapy for congestive heart failure (CHF). Because ischemic heart disease is the most common cause of CHF, aspirin is frequently given concomitantly with ACE inhibitors in patients with CHF. Increased bradykinin levels, with the consequent ...

journal_title：Current cardiology reports

authors： Moskowitz R

更新日期：2001-05-01 00:00:00

abstract：:The excess risk of hypertension in black Americans continues to be a major health concern. Although there is considerable information regarding these disease trends, much of the major underpinnings of the etiology of hypertension remain unclear. The excess mortality in blacks due to heart disease, renal failure, and s...

journal_title：Current cardiology reports

authors： Nesbitt SD

更新日期：2004-11-01 00:00:00

abstract：:The decline in the use of sodium channel blockers has led to an expanding use of b-blockers and complex class III agents such as sotalol and amiodarone for controlling cardiac arrhythmias. Success with these agents in the context of their side effects has spurred the development of compounds with simpler ion channel-b...

journal_title：Current cardiology reports

authors： Singh BN,Sarma JS

更新日期：2001-07-01 00:00:00

abstract：:Increasing barriers to medical device innovation in the United States including constrained financial resources and rising research costs require that physicians take on greater involvement in medical device development, evaluation, and regulatory processes. Such involvement requires that physicians understand basic a...

journal_title：Current cardiology reports

authors： Sastry A

更新日期：2014-01-01 00:00:00

abstract：:The accurate differentiation of viable and nonviable myocardium is crucial for therapy planning in patients with coronary artery disease and left ventricular dysfunction. Traditional techniques such as echocardiography, positron emission tomography, single photon emission computed tomography, and dobutamine echocardio...

journal_title：Current cardiology reports

authors： Wagner A,Mahrholdt H,Kim RJ,Judd RM

更新日期：2005-01-01 00:00:00

abstract：PURPOSE OF REVIEW:To establish the actual role of CT in the growing field of transcatheter valve interventions (THV). RECENT FINDINGS:The development of empirical CT measurements, which are linked with outcomes. CT is a reliable technique for assessing risk and planning transcatheter valve interventions for mitral and...

journal_title：Current cardiology reports

authors： Godoy M,Mugharbil A,Anastasius M,Leipsic J

更新日期：2019-11-25 00:00:00

abstract：:Cardiac surgery (CS) with cardiopulmonary bypass (CPB) is currently the most common surgery in the United States. Understanding, avoiding, and preventing postoperative complications, including neurologic deficits following CS, represents a great public and economic benefit for society, especially considering our aging...

journal_title：Current cardiology reports

authors： Razumovsky AY,Gugino LD,Owen JH

更新日期：2006-02-01 00:00:00

abstract：:Significant progress in research has been made in the areas of sex-specific aspects of cardiovascular disease. Despite these advances, coronary artery disease (CAD) is the leading cause of death of women in the Western world. Over the past decade, the focused research on women at risk for ischemic heart disease has he...

journal_title：Current cardiology reports

authors： Phillips LM,Mieres JH

更新日期：2010-03-01 00:00:00

abstract：:Management of severe chronic mitral regurgitation (MR) in severe heart failure is challenging. There are controversies over the efficacy of surgical correction of MR in the presence of severely depressed left ventricular (LV) function. The etiology of MR plays an important role in clinical decision making. In organic ...

journal_title：Current cardiology reports

authors： Pu M

更新日期：2006-05-01 00:00:00

abstract：:Despite a vast body of research on antithrombotic therapy for patients with cardiac disease, there are few clinical settings where robust evidence of their benefit exists. Patients with heart failure often have vascular disease and atrial fibrillation contributing to their poor prognosis. For patients with heart failu...

journal_title：Current cardiology reports

authors： Cleland JG,Mumtaz S,Cecchini L

更新日期：2012-06-01 00:00:00

abstract：:Noninvasive cardiac imaging techniques have made a striking impact on the evaluation and management of pericardial disorders. Two-dimensional and Doppler echocardiography are the methods of choice in the evaluation of pericardial effusion and cardiac tamponade. Magnetic resonance imaging, computed tomography, and tran...

journal_title：Current cardiology reports

authors： Karia DH,Xing YQ,Kuvin JT,Nesser HJ,Pandian NG

更新日期：2002-01-01 00:00:00

abstract：PURPOSE OF REVIEW:The goal of this paper is to review present knowledge regarding biological pacemakers created by somatic reprogramming as a platform for mechanistic and metabolic understanding of the rare subpopulation of pacemaker cells, with the ultimate goal of creating biological alternatives to electronic pacing...

journal_title：Current cardiology reports

authors： Xiao A,Cho HC

更新日期：2020-03-30 00:00:00

abstract：PURPOSE OF REVIEW:In this review, we summarise the evidence on the association between cardiovascular disease (CVD) and cognitive impairment and explore the role of the nitric oxide (NO) pathway as a causal mechanism. RECENT FINDINGS:Evidence from epidemiological studies suggests that the presence of CVD and its risk ...

journal_title：Current cardiology reports

authors： Stephan BCM,Harrison SL,Keage HAD,Babateen A,Robinson L,Siervo M

更新日期：2017-08-11 00:00:00

abstract：PURPOSE OF REVIEW:This review summarises and discusses the epidemiological evidence suggesting a causal relationship between sleep duration and cardio-metabolic risk and outcomes in population. RECENT FINDINGS:Sleep duration is affected by a variety of cultural, social, psychological, behavioural, pathophysiological a...

journal_title：Current cardiology reports

authors： Cappuccio FP,Miller MA

更新日期：2017-09-19 00:00:00

abstract：PURPOSE OF REVIEW:We provide a concise update on the contemporary management of cardiogenic shock in the setting of acute coronary syndrome (ACS). Early shock recognition, optimal selection and initiation of mechanical circulatory support (MCS), early coronary revascularization, and a team-based, protocol-driven approa...

journal_title：Current cardiology reports

authors： Bagai J,Brilakis ES

更新日期：2019-03-04 00:00:00