Prognostic Biomarkers in Acute Coronary Syndromes: Risk Stratification Beyond Cardiac Troponins.

abstract：:The long QT syndrome (LQTS) and the Brugada syndrome (BrS) are the most common genetic causes of malignant ventricular arrhythmias and sudden cardiac death in young patients with normal cardiac morphology. To date, more than 250 different mutations in seven genes have been identified as causing LQTS, whereas the only ...

journal_title：Current cardiology reports

authors： Goldenberg I,Moss AJ,Zareba W

更新日期：2005-09-01 00:00:00

abstract：PURPOSE OF REVIEW:To describe lipid abnormalities in diabetes, when they occur and the evidence base for lipid management with established and new drugs to prevent diabetes complications. We also discuss how to manage statin intolerance. RECENT FINDINGS:Statins remain first-line therapy in patients with diabetes, thou...

journal_title：Current cardiology reports

authors： Sillars A,Sattar N

更新日期：2019-11-22 00:00:00

abstract：PURPOSE OF REVIEW:The review is focused on "digital health", which means advanced analytics based on multi-modal data. The "Health Care Internet of Things", which uses sensors, apps, and remote monitoring could provide continuous clinical information in the cloud that enables clinicians to access the information they n...

journal_title：Current cardiology reports

authors： Mazzanti M,Shirka E,Gjergo H,Hasimi E

更新日期：2018-05-10 00:00:00

abstract：PURPOSE OF REVIEW:Results from cardiovascular (CV) outcome trials have revealed important insights into the CV safety and efficacy of glucose-lowering agents, including dipeptidyl peptidase-4 inhibitors (DPP-4i) and glucagon-like peptide-1 receptor agonists (GLP-1RA). RECENT FINDINGS:Among patients with T2DM, DPP-4i h...

journal_title：Current cardiology reports

authors： Patel KV,Sarraju A,Neeland IJ,McGuire DK

更新日期：2020-08-08 00:00:00

abstract：PURPOSE OF REVIEW:To assess current management strategies for advanced heart failure in adults with congenital heart disease, including heart transplantation and mechanical circulatory support. RECENT FINDINGS:Current data demonstrate that adults with CHD generally experience higher short-term mortality after heart tr...

journal_title：Current cardiology reports

authors： Serfas JD,Patel PA,Krasuski RA

更新日期：2018-08-09 00:00:00

abstract：:Catheter-based aortic valve implantation is increasingly being performed in high-risk patients with symptomatic aortic valve stenosis. For successful planning of the procedure, CT has been shown to provide crucial information concerning the aortic root as well as the peripheral access vessels. This article illustrates...

journal_title：Current cardiology reports

authors： Marwan M,Achenbach S

更新日期：2016-02-01 00:00:00

abstract：:Randomized clinical trials have established that lipid- lowering pharmacologic therapy can substantially reduce morbidity and mortality in patients with known coronary artery disease (CAD). Researchers are now working to define the role of lipid-lowering agents in the primary prevention of CAD to extend their benefit ...

journal_title：Current cardiology reports

authors： Nass CM,Wiviott SD,Allen JK,Post WS,Blumenthal aR

更新日期：2000-09-01 00:00:00

abstract：:Patients with severe carotid and coronary disease-especially if they require coronary artery bypass grafting (CABG)-are at high risk of cardiac events and stroke. Carotid revascularization should be considered for patients with symptomatic carotid disease and bilateral severe asymptomatic carotid stenosis. In patients...

journal_title：Current cardiology reports

authors： Roffi M,Ribichini F,Castriota F,Cremonesi A

更新日期：2012-04-01 00:00:00

abstract：:Dual antiplatelet therapy with aspirin and clopidogrel is a well-established standard of care for patients with acute coronary syndromes. Whether there are other drug strategies or therapies that will achieve fewer ischemic events, and at the same time be associated with fewer bleeding complications, is a question rec...

journal_title：Current cardiology reports

authors： Rajan L,Moliterno DJ

更新日期：2011-08-01 00:00:00

abstract：PURPOSE OF REVIEW:The cardiovascular (CV) risk related to lipid disorders is well established and is based on a robust body of evidence from well-designed randomized clinical trials, as well as prospective observational studies. In the last two decades, significant advances have been made in understanding the genetic b...

journal_title：Current cardiology reports

authors： Stein R,Ferrari F,Scolari F

更新日期：2019-06-21 00:00:00

abstract：PURPOSE OF REVIEW:An examination of the current ACC/AHA and ESC/EAS Guidelines on the management of dyslipidemias for common ground and differences. RECENT FINDINGS:There is much common ground. Both note that ASCVD is, in most people, the product of a number of risk factors, notably tobacco exposure, hyperlipidemia, h...

journal_title：Current cardiology reports

authors： Graham IM,Catapano AL

更新日期：2017-06-01 00:00:00

abstract：:Observational studies have established a strong association between the presence of patent foramen ovale (PFO) and increased risk of ischemic stroke. The mechanism involved is presumed to be a paradoxical embolism from a venous thrombus that travels via the PFO to the systemic circulation. The best treatment modality ...

journal_title：Current cardiology reports

authors： Rodriguez CJ,Homma S

更新日期：2004-03-01 00:00:00

abstract：:Chronic total occlusion (CTO) represents one of the most challenging lesion subsets faced by the interventional cardiologist. CTO is a common problem, being present in more than 30% of patients undergoing coronary angiography. Over the past 10 years, the success rate of recanalization has increased from approximately ...

journal_title：Current cardiology reports

authors： Genereux P,Dangas G

更新日期：2010-09-01 00:00:00

abstract：:The risk of stroke associated with carotid artery stenosis can be reduced with carotid endarterectomy or carotid artery stenting in carefully selected patients. While surgery has been the traditional treatment there have been many trials comparing carotid endarterectomy with carotid artery stenting, and stenting has s...

journal_title：Current cardiology reports

authors： Buschur M,Gurm HS

更新日期：2012-02-05 00:00:00

abstract：:Basic and animal research implicate inflammatory mechanisms in the pathogenesis and progression of atherosclerosis, plaque rupture, thrombosis, and stroke. Inflammatory biomarkers, particularly high-sensitivity C-reactive protein and lipoprotein-associated phospholipase A2, have been identified as potential predictors...

journal_title：Current cardiology reports

authors： Elkind MS

更新日期：2009-01-01 00:00:00

abstract：:Echocardiography is the most common noninvasive tool used in assessing cardiac masses. Real-time three-dimensional echocardiography expands the diagnostic capabilities of cardiac ultrasound in assessing the location, composition, size, and relationship to other structures of cardiac masses. The improved characterizati...

journal_title：Current cardiology reports

authors： Plana JC

更新日期：2009-05-01 00:00:00

abstract：:Management of severe chronic mitral regurgitation (MR) in severe heart failure is challenging. There are controversies over the efficacy of surgical correction of MR in the presence of severely depressed left ventricular (LV) function. The etiology of MR plays an important role in clinical decision making. In organic ...

journal_title：Current cardiology reports

authors： Pu M

更新日期：2006-05-01 00:00:00

abstract：PURPOSE OF REVIEW:To determine if subsidizing the cost of a food-based intervention for managing hyperlipidemia could be cost-effective under commercial insurance and/or Medicare coverage scenarios. RECENT FINDINGS:A large number of patients eligible for pharmaceutical treatment of hyperlipidemia either cannot or will...

journal_title：Current cardiology reports

authors： Dong I,Klodas E

更新日期：2020-09-10 00:00:00

abstract：PURPOSE OF THE REVIEW:The aim of this review was to discuss the role of cardiac magnetic resonance (CMR) for the prognostic stratification of cardiomyopathies, highlighting strengths and limitations. RECENT FINDINGS:CMR is considered as a diagnostic pillar in the management of non-ischemic cardiomyopathies. Over the l...

journal_title：Current cardiology reports

authors： Grigoratos C,Todiere G,Barison A,Aquaro GD

更新日期：2020-06-19 00:00:00

abstract：PURPOSE OF REVIEW:This review discusses the benefits of a completely percutaneous approach to endovascular aortic aneurysm repair (EVAR), and provides an outline as to how this is performed by a multidisciplinary team of cardiologists and cardiovascular surgeons at a quaternary care community hospital. RECENT FINDINGS...

journal_title：Current cardiology reports

authors： Huff CM,Silver MJ,Ansel GM

更新日期：2018-07-26 00:00:00

abstract：:The accurate differentiation of viable and nonviable myocardium is crucial for therapy planning in patients with coronary artery disease and left ventricular dysfunction. Traditional techniques such as echocardiography, positron emission tomography, single photon emission computed tomography, and dobutamine echocardio...

journal_title：Current cardiology reports

authors： Wagner A,Mahrholdt H,Kim RJ,Judd RM

更新日期：2005-01-01 00:00:00

abstract：:The most common cause of acute coronary syndrome (ACS) is rupture of an atherosclerotic lesion containing a large necrotic core and a thin fibrous cap followed by acute luminal thrombosis because the rupture of the thin fibrous cap allows contact of the platelets with the highly thrombogenic necrotic core. Pathologic ...

journal_title：Current cardiology reports

authors： Choi SY,Mintz GS

更新日期：2010-07-01 00:00:00

abstract：:Due to an increase in the number of patients with heart failure and ventricular arrhythmias, ventricular tachycardia ablation has a growing clinical role. Long-term success rates remain suboptimal and require creating a detailed electroanatomic map during the procedure to identify fibrotic areas responsible for arrhyt...

journal_title：Current cardiology reports

authors： Duell J,Dilsizian V,Smith M,Chen W,Dickfeld T

更新日期：2016-02-01 00:00:00

abstract：PURPOSE OF REVIEW:The last 40 years of clinical research in interventional cardiology were extraordinarily innovative. This article will review the most promising up and coming interventional cardiovascular therapies, with a primary focus on the treatment of coronary artery disease. RECENT FINDINGS:From the first sten...

journal_title：Current cardiology reports

authors： Kerneis M,Nafee T,Yee MK,Kazmi HA,Datta S,Zeitouni M,Afzal MK,Jafarizade M,Walia SS,Qamar I,Pitliya A,Kalayci A,Al Khalfan F,Gibson CM

更新日期：2019-03-13 00:00:00

abstract：PURPOSE OF REVIEW:The number of pregnancies complicated by valvular heart disease is increasing. This review describes the hemodynamic effects of clinically important valvular abnormalities during pregnancy and reviews current guideline-driven management strategies. RECENT FINDINGS:Valvular heart disease in women of c...

journal_title：Current cardiology reports

authors： Goldstein SA,Ward CC

更新日期：2017-08-24 00:00:00

abstract：:Leukocytes play a critical role in both the initial steps of atherogenesis and the late events of plaque instability and thrombosis. Leukocyte-endothelial cell adhesion molecules (CAMs) modulate the interaction between circulating leukocytes and the vessel wall. Levels of soluble CAMs are increased in patients with dy...

journal_title：Current cardiology reports

authors： Ballantyne CM,Abe Y

更新日期：1999-09-01 00:00:00

abstract：:Although clinical evidence indicates that many of the electrophysiologic and functional changes associated with atrial fibrillation (AF) can be reversed by maintaining normal sinus rhythm (NSR), a series of large-scale randomized trials failed to demonstrate that this strategy provides a survival advantage. These stud...

journal_title：Current cardiology reports

authors： Zimetbaum P

更新日期：2006-09-01 00:00:00

abstract：:Thrombolytic therapy aims to achieve rapid and sustained infarct-related artery patency, although this results in a procoagulant state. Heparin has limitations as an antithrombin agent, which has led to clinical investigation of alternative agents. Direct thrombin inhibitors, as adjuncts to thrombolytic therapy, have ...

journal_title：Current cardiology reports

authors： French JK,White HD

更新日期：1999-09-01 00:00:00

abstract：:Four non-communicable diseases-cardiovascular disease, chronic respiratory disease, diabetes mellitus, and cancer-account for over 60 % of all deaths globally. In recognition of this significant epidemic, the United Nations set forth a target of reducing the four major NCDs by 25 % by 2025. Cardiovascular disease alon...

journal_title：Current cardiology reports

authors： Dugani S,Gaziano TA

更新日期：2016-01-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of this report is to describe the main aspects of sex-related differences in non-ischemic dilated cardiomyopathies (DCM), focusing on chemotherapy-induced heart failure (HF) and investigating the possible therapeutic implications and clinical management applications in the era of personalized ...

journal_title：Current cardiology reports

authors： D'Amario D,Camilli M,Migliaro S,Canonico F,Galli M,Arcudi A,Montone RA,Borovac JA,Crea F,Savarese G

更新日期：2020-08-08 00:00:00