Heart Transplantation and Mechanical Circulatory Support in Adults with Congenital Heart Disease.

abstract：:Glycoprotein IIb/IIIa inhibitors and low molecular heparins are important new components of the medical treatment for acute coronary syndromes (ACS). Renal insufficiency is a common comorbid condition and high-risk marker for ACS. The safety and efficacy of these treatments in ACS are dependent on the pharmacokinetics...

journal_title：Current cardiology reports

authors： Rammohan C,Fintel D

更新日期：2003-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Cell therapy for cardiovascular diseases is regarded as a rapidly growing field within regenerative medicine. Different cellular populations enriched for cardiac progenitor cells (CPCs), or derivate a-cellular products, are currently under preclinical and clinical evaluation. Here, we have reviewed th...

journal_title：Current cardiology reports

authors： Pagano F,Picchio V,Angelini F,Iaccarino A,Peruzzi M,Cavarretta E,Biondi-Zoccai G,Sciarretta S,De Falco E,Chimenti I,Frati G

更新日期：2018-08-13 00:00:00

abstract：:Despite a vast body of research on antithrombotic therapy for patients with cardiac disease, there are few clinical settings where robust evidence of their benefit exists. Patients with heart failure often have vascular disease and atrial fibrillation contributing to their poor prognosis. For patients with heart failu...

journal_title：Current cardiology reports

authors： Cleland JG,Mumtaz S,Cecchini L

更新日期：2012-06-01 00:00:00

abstract：:Exercise intolerance in patients with chronic heart failure (CHF) shows no correlation to the degree of left ventricular dysfunction. This surprising finding has directed attention to peripheral changes in CHF: reduced endothelium-dependent vasodilation and altered skeletal muscle metabolism. Physical exercise trainin...

journal_title：Current cardiology reports

authors： Hambrecht R,Gielen S,Schuler G

更新日期：1999-05-01 00:00:00

abstract：:Diabetic patients who present with an acute coronary syndrome (ACS) have a particularly adverse prognosis, largely contributed by increased platelet reactivity and higher burden of disease severity. Diabetic patients with ACS derive a greater benefit from established therapies, particularly platelet-inhibiting therapi...

journal_title：Current cardiology reports

authors： Amin AP,Marso SP

更新日期：2010-07-01 00:00:00

abstract：:In STEMI, primary PCI restores macrovascular coronary blood flow effectively but microvascular perfusion remains a challenge. Thrombus has the potential to embolize to the microvasculature limiting effective coronary blood flow. Thrombus burden is associated with a higher mortality and manual aspiration thrombectomy h...

journal_title：Current cardiology reports

authors： Alak A,Jolly SS

更新日期：2016-03-01 00:00:00

abstract：:Implantable cardioverter-defibrillators (ICDs) significantly reduce mortality in patients with depressed left ventricular ejection fraction (LVEF) and heart failure (HF). However, shortcomings of LVEF to accurately identify those at greatest risk of ventricular tachyarrhythmias have led to the pursuit of alternative m...

journal_title：Current cardiology reports

authors： Klein T,Dilsizian V,Cao Q,Chen W,Dickfeld TM

更新日期：2013-05-01 00:00:00

abstract：:Basic and animal research implicate inflammatory mechanisms in the pathogenesis and progression of atherosclerosis, plaque rupture, thrombosis, and stroke. Inflammatory biomarkers, particularly high-sensitivity C-reactive protein and lipoprotein-associated phospholipase A2, have been identified as potential predictors...

journal_title：Current cardiology reports

authors： Elkind MS

更新日期：2009-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Monoclonal antibodies that inhibit proprotein convertase subtilisin/kexin type 9 (PCSK9) have emerged as a novel approach to low-density lipoprotein cholesterol (LDL-C) lowering. The potential role of PCSK9 inhibitors in clinical practice will be reviewed. RECENT FINDINGS:Clinical trials have demonst...

journal_title：Current cardiology reports

authors： King P,Nicholls SJ

更新日期：2017-08-01 00:00:00

abstract：:Due to an increase in the number of patients with heart failure and ventricular arrhythmias, ventricular tachycardia ablation has a growing clinical role. Long-term success rates remain suboptimal and require creating a detailed electroanatomic map during the procedure to identify fibrotic areas responsible for arrhyt...

journal_title：Current cardiology reports

authors： Duell J,Dilsizian V,Smith M,Chen W,Dickfeld T

更新日期：2016-02-01 00:00:00

abstract：:The rapid growth of medical knowledge during the past few decades has created many potential advances in the therapeutics of chronic disease, and cardiovascular disease has been at the center of this phenomenon. Translation of these advances into everyday care of patients with chronic disease continues to be problemat...

journal_title：Current cardiology reports

authors： Adams KF

更新日期：2001-03-01 00:00:00

abstract：:Thrombolytic therapy aims to achieve rapid and sustained infarct-related artery patency, although this results in a procoagulant state. Heparin has limitations as an antithrombin agent, which has led to clinical investigation of alternative agents. Direct thrombin inhibitors, as adjuncts to thrombolytic therapy, have ...

journal_title：Current cardiology reports

authors： French JK,White HD

更新日期：1999-09-01 00:00:00

abstract：:Clinical trials in the last decade have improved the quality of evidence to support preventive medical strategies to reduce the risk of recurrences after pericarditis. There are essentially three main strategies: (1) to use full anti-inflammatory doses for the treatment of each attack of pericarditis till symptoms res...

journal_title：Current cardiology reports

authors： Imazio M

更新日期：2015-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Tricuspid regurgitation is common; however, recognition and diagnosis, clinical outcomes, and management strategies are poorly defined. Here, we will describe the etiology and natural history of tricuspid regurgitation (TR), evaluate existing surgical outcomes data, and review the evolving field of pe...

journal_title：Current cardiology reports

authors： Al-Hijji M,Fender EA,El Sabbagh A,Holmes DR

更新日期：2017-09-14 00:00:00

abstract：:Patients from racial and ethnic minorities experience higher mortality after cardiac surgery compared to white patients, both during the early postoperative phase as well as long term. A number of factors likely explain poor outcomes in black and minority patients, which include differences in biology, comorbid health...

journal_title：Current cardiology reports

authors： Khera R,Vaughan-Sarrazin M,Rosenthal GE,Girotra S

更新日期：2015-05-01 00:00:00

abstract：:Angiotensin-converting enzyme (ACE) inhibitors have become the cornerstone of therapy for congestive heart failure (CHF). Because ischemic heart disease is the most common cause of CHF, aspirin is frequently given concomitantly with ACE inhibitors in patients with CHF. Increased bradykinin levels, with the consequent ...

journal_title：Current cardiology reports

authors： Moskowitz R

更新日期：2001-05-01 00:00:00

abstract：:Deformation imaging by tissue Doppler imaging (TDI) and speckle-tracking echocardiography (STE) are emerging clinical methods. TDI- and STE-derived parameters, such as myocardial strain and strain rate, as well as torsion and twist, provide detailed information about myocardial function and are associated with cardiov...

journal_title：Current cardiology reports

authors： Opdahl A,Helle-Valle T,Skulstad H,Smiseth OA

更新日期：2015-03-01 00:00:00

abstract：:As more and more patients receive complex implantable cardioverter-defibrillators (ICDs), profound knowledge about the incidence of inappropriate device therapy, the reasons it happens, and the possibilities for prevention is crucial. In this article, the most important prevention algorithms incorporated in current IC...

journal_title：Current cardiology reports

authors： Schaer B,Osswald S

更新日期：2000-07-01 00:00:00

abstract：PURPOSE OF REVIEW:The number of pregnancies complicated by valvular heart disease is increasing. This review describes the hemodynamic effects of clinically important valvular abnormalities during pregnancy and reviews current guideline-driven management strategies. RECENT FINDINGS:Valvular heart disease in women of c...

journal_title：Current cardiology reports

authors： Goldstein SA,Ward CC

更新日期：2017-08-24 00:00:00

abstract：:Four non-communicable diseases-cardiovascular disease, chronic respiratory disease, diabetes mellitus, and cancer-account for over 60 % of all deaths globally. In recognition of this significant epidemic, the United Nations set forth a target of reducing the four major NCDs by 25 % by 2025. Cardiovascular disease alon...

journal_title：Current cardiology reports

authors： Dugani S,Gaziano TA

更新日期：2016-01-01 00:00:00

abstract：:Hypertension in patients with renovascular disease poses a major clinical challenge. Renal arterial disease accelerates hypertension by activation of multiple pressor systems. Although younger individuals with fibromuscular lesions often respond well to angioplasty with minor associated risks, care must be taken in ca...

journal_title：Current cardiology reports

authors： Textor SC

更新日期：2007-11-01 00:00:00

abstract：PURPOSE OF REVIEW:This review presents the current available evidence of the effects of several dietary patterns on atherosclerotic cardiovascular disease (ASCVD) risk in patients with type 2 diabetes (T2D). RECENT FINDINGS:Evidence demonstrates improvements in cardiovascular risk factors with some dietary patterns in...

journal_title：Current cardiology reports

authors： Liday C,Kirkpatrick C

更新日期：2019-10-17 00:00:00

abstract：:Patients with severe carotid and coronary disease-especially if they require coronary artery bypass grafting (CABG)-are at high risk of cardiac events and stroke. Carotid revascularization should be considered for patients with symptomatic carotid disease and bilateral severe asymptomatic carotid stenosis. In patients...

journal_title：Current cardiology reports

authors： Roffi M,Ribichini F,Castriota F,Cremonesi A

更新日期：2012-04-01 00:00:00

abstract：:Coronary artery bypass grafting without the aid of cardiopulmonary bypass (CPB) continues to gain popularity as an alternative to standard techniques of revascularization. CPB with cardioplegic arrest is associated with complications that may negate an otherwise technically flawless procedure. Experience has identifie...

journal_title：Current cardiology reports

authors： Dewey TM,Mack MJ

更新日期：1999-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Cardiac troponin (cTn) plays an essential role for assessment of outcome in acute coronary syndrome (ACS). However, the prognostic value of cTn is not absolute. In this mini-review, we summarize the evidence on the utility of established biomarkers of left-ventricular dysfunction, hemodynamic stress, ...

journal_title：Current cardiology reports

authors： Eggers KM,Lindahl B

更新日期：2017-04-01 00:00:00

abstract：:Controlled clinical trials, performed in more than 13,000 patients, have consistently shown the beneficial effects of long-term beta-blocker therapy in patients with chronic heart failure. However, it is not clear whether this is a class effect or if it is specific only for some agents. Beneficial effects on the progn...

journal_title：Current cardiology reports

authors： Metra M,Nodari S,Boldi E,Dei Cas L

更新日期：2000-05-01 00:00:00

abstract：PURPOSE OF REVIEW:This review provides an update on rheumatic mitral stenosis. Acute rheumatic fever (RF), the sequela of group A β-hemolytic streptococcal infection, is the major etiology for mitral stenosis (MS). RECENT FINDINGS:While the incidence of acute RF in the Western world had substantially declined over the...

journal_title：Current cardiology reports

authors： Wunderlich NC,Dalvi B,Ho SY,Küx H,Siegel RJ

更新日期：2019-02-28 00:00:00

abstract：:On page 2 of the original publication, in the section on TTR Silencers dosing of patisiran in the APOLLO study was stated as being given every 3 months; this is inaccurate as patisiran was dosed every 3 weeks in the APOLLO study. ...

journal_title：Current cardiology reports

authors： Hough A,Wearden J,de Almeida K,Kaiser S

更新日期：2020-09-28 00:00:00

abstract：:Conventional algorithms and noninvasive imaging tests for the identification of stable, hemodynamically significant coronary artery disease offer little insight into the detection of potentially vulnerable and inflamed coronary plaques, those most likely to rupture and cause acute coronary syndromes. Positron emission...

journal_title：Current cardiology reports

authors： Rogers IS,Tawakol A

更新日期：2011-04-01 00:00:00

abstract：:Dual antiplatelet therapy with aspirin and clopidogrel is a well-established standard of care for patients with acute coronary syndromes. Whether there are other drug strategies or therapies that will achieve fewer ischemic events, and at the same time be associated with fewer bleeding complications, is a question rec...

journal_title：Current cardiology reports

authors： Rajan L,Moliterno DJ

更新日期：2011-08-01 00:00:00