Management of patients with stroke and a patent foramen ovale.

Abstract:

:Observational studies have established a strong association between the presence of patent foramen ovale (PFO) and increased risk of ischemic stroke. The mechanism involved is presumed to be a paradoxical embolism from a venous thrombus that travels via the PFO to the systemic circulation. The best treatment modality to prevent recurrent stroke in patients with PFO remains undefined. There are four major choices: 1) medical therapy with anticoagulants, 2) medical therapy with antiplatelet agents, 3) surgical closure, and 4) percutaneous device closure. The Patent Foramen Ovale in Cryptogenic Stroke Study has demonstrated that antiplatelet and anticoagulant therapies are of equal benefit in preventing recurrent neurologic events in stroke patients with a PFO. Medical therapy should remain as the initial choice of secondary prophylactic therapy. PFO closure, either surgical or percutaneous, may further reduce event rates; however, this remains to be demonstrated because no randomized trial to date has compared PFO closure with medical therapy.

journal_name

Curr Cardiol Rep

authors

Rodriguez CJ,Homma S

doi

10.1007/s11886-004-0013-z

keywords:

subject

Has Abstract

pub_date

2004-03-01 00:00:00

pages

143-6

issue

2

eissn

1523-3782

issn

1534-3170

journal_volume

6

pub_type

杂志文章,评审
  • The Biological Mechanisms of Action of Cardiac Progenitor Cell Therapy.

    abstract:PURPOSE OF REVIEW:Cell therapy for cardiovascular diseases is regarded as a rapidly growing field within regenerative medicine. Different cellular populations enriched for cardiac progenitor cells (CPCs), or derivate a-cellular products, are currently under preclinical and clinical evaluation. Here, we have reviewed th...

    journal_title:Current cardiology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11886-018-1031-6

    authors: Pagano F,Picchio V,Angelini F,Iaccarino A,Peruzzi M,Cavarretta E,Biondi-Zoccai G,Sciarretta S,De Falco E,Chimenti I,Frati G

    更新日期:2018-08-13 00:00:00

  • Radial Versus Femoral Access for Acute Coronary Syndromes.

    abstract::The feasibility and safety of transradial coronary intervention was demonstrated soon after the description of the transfemoral approach, despite which the use of the femoral artery still dominates in acute coronary syndrome intervention. The advantages of using the radial artery are virtual elimination of access site...

    journal_title:Current cardiology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11886-015-0676-7

    authors: Routledge H,Sastry S

    更新日期:2015-12-01 00:00:00

  • Subclinical cardiovascular disease assessment in persons with diabetes.

    abstract::Patients with diabetes mellitus are at particularly high risk for cardiovascular disease. Although global risk factor scoring systems, such as the Framingham Risk Score, are well established for screening asymptomatic adults, they are not as predictive in diabetics. Therefore, there has been considerable interest in n...

    journal_title:Current cardiology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11886-013-0358-2

    authors: Warraich HJ,Nasir K

    更新日期:2013-05-01 00:00:00

  • Routine Angiographic Follow-Up After Coronary Artery Disease Revascularization: Is Seeing Believing?

    abstract:PURPOSE OF THE REVIEW:Coronary artery disease is a major cause of mortality and morbidity in the world, and PCI and CABG account for over a million procedures performed annually in the USA. The goal of percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) is to achieve complete revasculariz...

    journal_title:Current cardiology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11886-018-0957-z

    authors: Agrawal H,Teleb M,Lahsaei S,Carbajal L,Montanez R,Carrozza JP Jr

    更新日期:2018-03-06 00:00:00

  • Lifestyle Interventions to Prevent Cardiovascular Events After Stroke and Transient Ischemic Attack.

    abstract:PURPOSE OF REVIEW:To summarize lifestyle interventions including pharmacological and non-pharmacological methods targeting modifiable risk factors and their impact on the future cardiovascular events in patients who have suffered transient ischemic attack (TIA) and/or ischemic stroke (IS). RECENT FINDINGS:The latest r...

    journal_title:Current cardiology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11886-019-1132-x

    authors: Vellipuram AR,Rodriguez G,Rawla P,Maud A,Cruz-Flores S,Khatri R

    更新日期:2019-04-22 00:00:00

  • Improving Medication Adherence in Coronary Heart Disease.

    abstract:PURPOSE OF REVIEW:The purpose of this review was to synthesize research findings from recently published randomized controlled trials (RCTs) targeting any phase of medication adherence, from initiation to discontinuation, among patients with coronary heart disease (CHD). RECENT FINDINGS:We identified successful strate...

    journal_title:Current cardiology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11886-017-0918-y

    authors: Zullig LL,Ramos K,Bosworth HB

    更新日期:2017-09-22 00:00:00

  • Amiodarone: a multifaceted antiarrhythmic drug.

    abstract::Synthesized as an antianginal compound 40 years ago, amiodarone has emerged as a uniquely effective antiarrhythmic compound in recent years. It has numerous properties, the most prominent being the ability to lengthen repolarization in the atria and ventricles associated with bradycardia without the significant potent...

    journal_title:Current cardiology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11886-006-0074-2

    authors: Singh BN

    更新日期:2006-09-01 00:00:00

  • Stroke prevention in atrial fibrillation: atrial appendage closure.

    abstract::The left atrial appendage (LAA) is the primary nonvalvular cause of cardioembolic stroke in patients with atrial fibrillation (AF). Warfarin and direct thrombin inhibitors such as dabigatran are presumed to prevent formation of LAA thrombus, and are first-line treatments to prevent ischemic stroke in AF. However, thes...

    journal_title:Current cardiology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11886-010-0162-1

    authors: Fuller CJ,Reisman M

    更新日期:2011-04-01 00:00:00

  • What niche will newer class III antiarrhythmic drugs occupy?

    abstract::The decline in the use of sodium channel blockers has led to an expanding use of b-blockers and complex class III agents such as sotalol and amiodarone for controlling cardiac arrhythmias. Success with these agents in the context of their side effects has spurred the development of compounds with simpler ion channel-b...

    journal_title:Current cardiology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11886-001-0086-x

    authors: Singh BN,Sarma JS

    更新日期:2001-07-01 00:00:00

  • Prevention, Diagnosis, and Treatment of Cardiac Implantable Electronic Device Infections.

    abstract::Cardiac implantable electronic device (CIED) infections are complex medical problems that are increasingly encountered. They are associated with significant morbidity and mortality with tremendous economic cost. The current review will emphasize the prevention, diagnosis, and treatment of this clinical entity using th...

    journal_title:Current cardiology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11886-016-0733-x

    authors: Leung S,Danik S

    更新日期:2016-06-01 00:00:00

  • Percutaneous Endovascular Aortic Aneurysm Repair for Abdominal Aortic Aneurysm.

    abstract:PURPOSE OF REVIEW:This review discusses the benefits of a completely percutaneous approach to endovascular aortic aneurysm repair (EVAR), and provides an outline as to how this is performed by a multidisciplinary team of cardiologists and cardiovascular surgeons at a quaternary care community hospital. RECENT FINDINGS...

    journal_title:Current cardiology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11886-018-1023-6

    authors: Huff CM,Silver MJ,Ansel GM

    更新日期:2018-07-26 00:00:00

  • Restoring normal sinus rhythm in atrial fibrillation : evidence from pharmacologic therapy and catheter ablation trials.

    abstract::Although clinical evidence indicates that many of the electrophysiologic and functional changes associated with atrial fibrillation (AF) can be reversed by maintaining normal sinus rhythm (NSR), a series of large-scale randomized trials failed to demonstrate that this strategy provides a survival advantage. These stud...

    journal_title:Current cardiology reports

    pub_type: 杂志文章

    doi:10.1007/s11886-006-0078-y

    authors: Zimetbaum P

    更新日期:2006-09-01 00:00:00

  • Antiarrhythmic drugs 2013: state of the art.

    abstract::Antiarrhythmic drugs are widely used, but are of modest efficacy and have important side effects. However, even with the advance of catheter ablation for atrial fibrillation and ventricular tachycardia, antiarrhythmic drugs remain an important tool for treating arrhythmias. Antiarrhythmic drug development has remained...

    journal_title:Current cardiology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11886-013-0410-2

    authors: Kumar K,Zimetbaum PJ

    更新日期:2013-10-01 00:00:00

  • Renovascular hypertension in 2007: where are we now?

    abstract::Hypertension in patients with renovascular disease poses a major clinical challenge. Renal arterial disease accelerates hypertension by activation of multiple pressor systems. Although younger individuals with fibromuscular lesions often respond well to angioplasty with minor associated risks, care must be taken in ca...

    journal_title:Current cardiology reports

    pub_type: 杂志文章,评审

    doi:10.1007/BF02938389

    authors: Textor SC

    更新日期:2007-11-01 00:00:00

  • The growing problem of stroke among young adults.

    abstract::Although overall stroke incidence has been declining in developed countries, there is evidence that stroke in the young is increasing. Increasing incidence may be particularly pronounced among minorities in whom historically a higher burden of stroke has been reported. Compared with older adults, time spent with disab...

    journal_title:Current cardiology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11886-013-0421-z

    authors: Sultan S,Elkind MS

    更新日期:2013-12-01 00:00:00

  • Choosing the best contraceptive method for the adult with congenital heart disease.

    abstract::As women with congenital heart disease (CHD) approach childbearing age, issues such as pregnancy and contraception need to be addressed. Women with CHD represent a heterogeneous population. While some have simple cardiac lesions and thus have contraceptive risks that are no different from those of the general populati...

    journal_title:Current cardiology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11886-009-0043-7

    authors: Silversides CK,Sermer M,Siu SC

    更新日期:2009-07-01 00:00:00

  • Endocardial pacing: the wave of the future?

    abstract::Cardiac resynchronization therapy (CRT) is a proven treatment for heart failure and requires the implantation of a left ventricular (LV) lead, usually placed in a tributary of the coronary sinus. Encouraged by the fact that approximately 30 % of the patients receiving CRT do not benefit from this therapy, LV endocardi...

    journal_title:Current cardiology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11886-012-0298-2

    authors: Bordachar P,Ploux S,Lumens J

    更新日期:2012-10-01 00:00:00

  • Cardiovascular Effects of Dipeptidyl Peptidase-4 Inhibitors and Glucagon-Like Peptide-1 Receptor Agonists: a Review for the General Cardiologist.

    abstract:PURPOSE OF REVIEW:Results from cardiovascular (CV) outcome trials have revealed important insights into the CV safety and efficacy of glucose-lowering agents, including dipeptidyl peptidase-4 inhibitors (DPP-4i) and glucagon-like peptide-1 receptor agonists (GLP-1RA). RECENT FINDINGS:Among patients with T2DM, DPP-4i h...

    journal_title:Current cardiology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11886-020-01355-5

    authors: Patel KV,Sarraju A,Neeland IJ,McGuire DK

    更新日期:2020-08-08 00:00:00

  • Global risk assessment for lipid therapy to prevent coronary heart disease.

    abstract::Randomized clinical trials have established that lipid- lowering pharmacologic therapy can substantially reduce morbidity and mortality in patients with known coronary artery disease (CAD). Researchers are now working to define the role of lipid-lowering agents in the primary prevention of CAD to extend their benefit ...

    journal_title:Current cardiology reports

    pub_type: 杂志文章

    doi:10.1007/s11886-000-0056-8

    authors: Nass CM,Wiviott SD,Allen JK,Post WS,Blumenthal aR

    更新日期:2000-09-01 00:00:00

  • Large-Scale Genomic Biobanks and Cardiovascular Disease.

    abstract:PURPOSE OF REVIEW:Cardiovascular disease is a leading cause of morbidity and mortality worldwide and is the focus of extensive biomedical research. Large genetic consortia combining data from many traditional prospective cohort and ascertained case-control study designs have facilitated the discovery of genetic associa...

    journal_title:Current cardiology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11886-018-0969-8

    authors: Small AM,O'Donnell CJ,Damrauer SM

    更新日期:2018-03-08 00:00:00

  • Diagnosing and Managing Primary Aldosteronism in Hypertensive Patients: a Case-Based Approach.

    abstract::Primary aldosteronism with a prevalence of 8 % of hypertension and 20 % of pharmacologically resistant hypertension is the most common secondary cause of hypertension. Yet, the diagnosis is missed in the vast majority of patients. Current clinical practice guidelines recommend screening for primary aldosteronism in pa...

    journal_title:Current cardiology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11886-016-0774-1

    authors: Carey RM

    更新日期:2016-10-01 00:00:00

  • Genetics of lipid traits and relationship to coronary artery disease.

    abstract::Despite the critical importance of plasma lipoproteins in the development of atherosclerosis, varying degrees of evidence surround the causal associations of lipoproteins with coronary artery disease (CAD). These causal contributions can be assessed by employing genetic variants as unbiased proxies for lipid levels. A...

    journal_title:Current cardiology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11886-013-0396-9

    authors: Keenan TE,Rader DJ

    更新日期:2013-09-01 00:00:00

  • Acute coronary syndrome in the patient with diabetes: is the management different?

    abstract::Diabetic patients who present with an acute coronary syndrome (ACS) have a particularly adverse prognosis, largely contributed by increased platelet reactivity and higher burden of disease severity. Diabetic patients with ACS derive a greater benefit from established therapies, particularly platelet-inhibiting therapi...

    journal_title:Current cardiology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11886-010-0118-5

    authors: Amin AP,Marso SP

    更新日期:2010-07-01 00:00:00

  • Coronary Artery Anomalies: When You Need to Worry.

    abstract:PURPOSE OF REVIEW:There is a broad spectrum of coronary artery anomalies that cardiologists may encounter either incidentally or during evaluation for cardiac symptoms. These anomalies include anomalous coronary arteries arising from the opposite sinus of Valsalva (ACAOS), coronary fistulae, and coronary artery aneurys...

    journal_title:Current cardiology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11886-017-0854-x

    authors: Kochar A,Kiefer T

    更新日期:2017-05-01 00:00:00

  • Shared Decision-Making and Patient Empowerment in Preventive Cardiology.

    abstract::Shared decision-making, central to evidence-based medicine and good patient care, begins and ends with the patient. It is the process by which a clinician and a patient jointly make a health decision after discussing options, potential benefits and harms, and considering the patient's values and preferences. Patient e...

    journal_title:Current cardiology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11886-016-0729-6

    authors: Kambhampati S,Ashvetiya T,Stone NJ,Blumenthal RS,Martin SS

    更新日期:2016-05-01 00:00:00

  • Targeted Nuclear Imaging Probes for Cardiac Amyloidosis.

    abstract:PURPOSE OF REVIEW:The aim of the present manuscript is to review the latest advancements of radionuclide molecular imaging in the diagnosis and prognosis of individuals with cardiac amyloidosis. RECENT FINDINGS:99mTechnetium labeled bone tracer scintigraphy had been known to image cardiac amyloidosis, since the 1980s;...

    journal_title:Current cardiology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11886-017-0868-4

    authors: Bravo PE,Dorbala S

    更新日期:2017-07-01 00:00:00

  • Exome sequencing: new insights into lipoprotein disorders.

    abstract::Several next generation sequencing platforms allow for a DNA-to-diagnosis protocol to identify the molecular basis of monogenic dyslipidemias. However, recent reports of the application of whole genome or whole exome sequencing in families with severe dyslipidemias have largely identified genetic variants in known lip...

    journal_title:Current cardiology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11886-014-0507-2

    authors: Farhan SM,Hegele RA

    更新日期:2014-07-01 00:00:00

  • Leadless Cardiac Pacemakers: Pacing Paradigm Change.

    abstract::Traditional transvenous approach for permanent cardiac pacing can be associated with significant acute and chronic complications related partly to either the insertion of transvenous lead or subcutaneous placement of pacemaker device. We summarize the current status of a novel self-contained leadless cardiac pacemaker...

    journal_title:Current cardiology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11886-015-0619-3

    authors: Neuzil P,Reddy VY

    更新日期:2015-08-01 00:00:00

  • Functional Information in Coronary Artery Disease: The Case of Computed Tomography Myocardial Perfusion.

    abstract:PURPOSE OF REVIEW:To review methodological and logistical aspects of CT myocardial perfusion, current clinical evidence and possible future directions, with specific focus on use in patients with coronary artery disease (CAD). RECENT FINDINGS:CT myocardial perfusion imaging may be performed as an add-on to standard co...

    journal_title:Current cardiology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11886-017-0937-8

    authors: Kofoed KF,Sørgaard MH,Linde JJ

    更新日期:2017-10-25 00:00:00

  • The role of renal denervation in the treatment of heart failure.

    abstract::The heart and kidney interact in terms of hemodynamics and neurohumoral regulatory mechanisms, and this helps to maintain circulatory homeostasis under normal conditions. However, the normal regulatory mechanisms become inappropriate in the setting of congestive heart failure (CHF), and significant renal dysfunction o...

    journal_title:Current cardiology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11886-012-0258-x

    authors: Sobotka PA,Krum H,Böhm M,Francis DP,Schlaich MP

    更新日期:2012-06-01 00:00:00