Exome sequencing: new insights into lipoprotein disorders.

abstract：:The decline in the use of sodium channel blockers has led to an expanding use of b-blockers and complex class III agents such as sotalol and amiodarone for controlling cardiac arrhythmias. Success with these agents in the context of their side effects has spurred the development of compounds with simpler ion channel-b...

journal_title：Current cardiology reports

authors： Singh BN,Sarma JS

更新日期：2001-07-01 00:00:00

abstract：:There has been considerable attention in recent years to the intriguing hypothesis that coronary heart disease and other atherosclerotic diseases may be caused by infection with pathogens such as Chlamydia pneumoniae, Helicobacter pylori, and cytomegalovirus. Supporting this hypothesis are studies that localize bacter...

journal_title：Current cardiology reports

authors： O'Donnell CJ,Levy D

更新日期：2000-07-01 00:00:00

abstract：PURPOSE OF REVIEW:An examination of the current ACC/AHA and ESC/EAS Guidelines on the management of dyslipidemias for common ground and differences. RECENT FINDINGS:There is much common ground. Both note that ASCVD is, in most people, the product of a number of risk factors, notably tobacco exposure, hyperlipidemia, h...

journal_title：Current cardiology reports

authors： Graham IM,Catapano AL

更新日期：2017-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Cell therapy for cardiovascular diseases is regarded as a rapidly growing field within regenerative medicine. Different cellular populations enriched for cardiac progenitor cells (CPCs), or derivate a-cellular products, are currently under preclinical and clinical evaluation. Here, we have reviewed th...

journal_title：Current cardiology reports

authors： Pagano F,Picchio V,Angelini F,Iaccarino A,Peruzzi M,Cavarretta E,Biondi-Zoccai G,Sciarretta S,De Falco E,Chimenti I,Frati G

更新日期：2018-08-13 00:00:00

abstract：:Diastolic dysfunction in patients with hypertension may present as asymptomatic findings on noninvasive testing, or as fulminant pulmonary edema, despite normal left ventricular systolic function. Up to 40% of hypertensive patients presenting with clinical signs of congestive heart failure have normal systolic left ve...

journal_title：Current cardiology reports

authors： Phillips RA,Diamond JA

更新日期：2001-11-01 00:00:00

abstract：:Primary percutaneous coronary intervention (PCI) with adjunctive glycoprotein (GP) IIb/IIIa receptor inhibitor therapy administered in the cardiac catheterization laboratory is the optimal reperfusion strategy for patients with ST-elevation myocardial infarction. Most available data regarding these agents are from tri...

journal_title：Current cardiology reports

authors： Tamhane UU,Gurm HS

更新日期：2008-09-01 00:00:00

abstract：:Resistant hypertension has evolved as an important global health care problem. Primary aldosteronism is one of several potentially reversible causes of resistant hypertension. Primary aldosteronism can be effectively treated, when recognized, with a mineralocorticoid receptor antagonist, such as spironolactone and epl...

journal_title：Current cardiology reports

authors： Sica DA

更新日期：2011-12-01 00:00:00

abstract：PURPOSE OF REVIEW:There is a broad spectrum of coronary artery anomalies that cardiologists may encounter either incidentally or during evaluation for cardiac symptoms. These anomalies include anomalous coronary arteries arising from the opposite sinus of Valsalva (ACAOS), coronary fistulae, and coronary artery aneurys...

journal_title：Current cardiology reports

authors： Kochar A,Kiefer T

更新日期：2017-05-01 00:00:00

abstract：:The assessment of myocardial viability may be an important component of the evaluation of patients with coronary artery disease and left ventricular dysfunction. The primary goal of viability assessment in such patients is to guide therapeutic decisions by determining which patients would most likely benefit from reva...

journal_title：Current cardiology reports

authors： Arrighi JA,Dilsizian V

更新日期：2012-04-01 00:00:00

abstract：:Percutaneous coronary intervention (PCI) of multivessel and/or left main stem disease have been shown to be potentially legitimate revascularization alternatives in appropriately selected patients. Risk stratification is an important component in guiding patients to identify the most appropriate revascularization moda...

journal_title：Current cardiology reports

authors： Farooq V,Brugaletta S,Serruys PW

更新日期：2011-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Cardiovascular disease is a leading cause of morbidity and mortality worldwide and is the focus of extensive biomedical research. Large genetic consortia combining data from many traditional prospective cohort and ascertained case-control study designs have facilitated the discovery of genetic associa...

journal_title：Current cardiology reports

authors： Small AM,O'Donnell CJ,Damrauer SM

更新日期：2018-03-08 00:00:00

abstract：:During the past years, non-neuronal vascular nicotinic acetylcholine receptors (nAChRs) increasingly have gained interest in cardiovascular research, as they are known to mediate the deleterious effects of nicotine and nitrosamines, components of tobacco smoke, on the vasculature. Because smoking is a major risk facto...

journal_title：Current cardiology reports

authors： Bauwens M,Mottaghy FM,Bucerius J

更新日期：2015-08-01 00:00:00

abstract：:Innate differences in gender physiology result in unique exposures, risk, and protection that are specific to women. Recognition and appreciation of these differences results in better treatment adaptations for women and better outcomes. Disparities between genders in the treatment of major cardiovascular risk factors...

journal_title：Current cardiology reports

authors： Jarvie JL,Foody JM

更新日期：2010-11-01 00:00:00

abstract：:Due to an increase in the number of patients with heart failure and ventricular arrhythmias, ventricular tachycardia ablation has a growing clinical role. Long-term success rates remain suboptimal and require creating a detailed electroanatomic map during the procedure to identify fibrotic areas responsible for arrhyt...

journal_title：Current cardiology reports

authors： Duell J,Dilsizian V,Smith M,Chen W,Dickfeld T

更新日期：2016-02-01 00:00:00

abstract：:Gut microbiota has been recently established to have a contributory role in the development of cardiometabolic disorders, such as atherosclerosis, obesity, and type 2 diabetes. Growing interest has focused on the modulation of gut microbiota as a therapeutic strategy in cardiovascular diseases and metabolic disorders....

journal_title：Current cardiology reports

authors： Miele L,Giorgio V,Alberelli MA,De Candia E,Gasbarrini A,Grieco A

更新日期：2015-12-01 00:00:00

abstract：:Advances in the field of molecular medicine are making gene therapy a viable treatment strategy for the next millennium. Indeed, over the past 10 years, a number of improvements have occurred that have resulted in an increased interest in gene therapy for the treatment of diseases in cardiovascular medicine. Because a...

journal_title：Current cardiology reports

authors： Channon KM,Annex BH

更新日期：2000-01-01 00:00:00

abstract：PURPOSE:This paper reviews the double-kiss crush (DK crush) technique in coronary artery bifurcation lesions. The technical aspects of the procedure and the clinical data supporting its use are summarized. RECENT FINDINGS:Randomized studies support the adoption of DK technique in complex bifurcation lesions for both l...

journal_title：Current cardiology reports

authors： Lynn BS,Hermiller JB

更新日期：2018-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Congenital heart disease is the most common birth defect and acquired heart disease is the leading cause of death in adults. Understanding the mechanisms that drive cardiomyocyte proliferation and differentiation has the potential to advance the understanding and potentially the treatment of different...

journal_title：Current cardiology reports

authors： Yester JW,Kühn B

更新日期：2017-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Monoclonal antibodies that inhibit proprotein convertase subtilisin/kexin type 9 (PCSK9) have emerged as a novel approach to low-density lipoprotein cholesterol (LDL-C) lowering. The potential role of PCSK9 inhibitors in clinical practice will be reviewed. RECENT FINDINGS:Clinical trials have demonst...

journal_title：Current cardiology reports

authors： King P,Nicholls SJ

更新日期：2017-08-01 00:00:00

abstract：:Echocardiography is the most common noninvasive tool used in assessing cardiac masses. Real-time three-dimensional echocardiography expands the diagnostic capabilities of cardiac ultrasound in assessing the location, composition, size, and relationship to other structures of cardiac masses. The improved characterizati...

journal_title：Current cardiology reports

authors： Plana JC

更新日期：2009-05-01 00:00:00

abstract：:Patients with severe carotid and coronary disease-especially if they require coronary artery bypass grafting (CABG)-are at high risk of cardiac events and stroke. Carotid revascularization should be considered for patients with symptomatic carotid disease and bilateral severe asymptomatic carotid stenosis. In patients...

journal_title：Current cardiology reports

authors： Roffi M,Ribichini F,Castriota F,Cremonesi A

更新日期：2012-04-01 00:00:00

abstract：:Although assessment of traditional coronary heart disease risk factors can often stratify individuals into low- or high-risk categories, additional means are needed to more precisely classify people clinically defined as intermediate-risk, to guide the intensity of risk-reducing therapies. The recognition that inflamm...

journal_title：Current cardiology reports

authors： Corson MA

更新日期：2009-11-01 00:00:00

abstract：:Patients with diabetes mellitus are at particularly high risk for cardiovascular disease. Although global risk factor scoring systems, such as the Framingham Risk Score, are well established for screening asymptomatic adults, they are not as predictive in diabetics. Therefore, there has been considerable interest in n...

journal_title：Current cardiology reports

authors： Warraich HJ,Nasir K

更新日期：2013-05-01 00:00:00

abstract：PURPOSE OF REVIEW:To create awareness for the devastating influence of high cholesterol in familial hypercholesterolaemia (FH) on vessel walls. Persons with high LDL-C and a known mutation associated with FH have a 22-fold increase in CVD compared with those with a normal LDL-C and no genetic mutation. If the awareness...

journal_title：Current cardiology reports

authors： Wiegman A

更新日期：2018-08-09 00:00:00

abstract：:The article title in the original publication contains a mistake. ...

journal_title：Current cardiology reports

authors： Edelson JB,Genuardi MV,Santangeli P,Birati EY

更新日期：2020-09-08 00:00:00

abstract：:Observational studies have established a strong association between the presence of patent foramen ovale (PFO) and increased risk of ischemic stroke. The mechanism involved is presumed to be a paradoxical embolism from a venous thrombus that travels via the PFO to the systemic circulation. The best treatment modality ...

journal_title：Current cardiology reports

authors： Rodriguez CJ,Homma S

更新日期：2004-03-01 00:00:00

abstract：:Atherosclerosis is the proximate cause of arterial thrombosis, leading to acute occlusive cardiovascular syndromes. Thrombosis in atherosclerosis usually results from rupture of the fibrous cap of atherosclerotic plaques with a smaller proportion resulting from superficial endothelial erosion. Ruptured plaques are oft...

journal_title：Current cardiology reports

authors： Shah PK

更新日期：2014-12-01 00:00:00

abstract：PURPOSE OF REVIEW:To analyze the current state of the art of functional mitral regurgitation (FMR) treatment. RECENT FINDINGS:The first-line treatment of severe FMR consists of guideline medical therapy (GMT) and resynchronization therapy when indicated; the impact of new medical therapies like sacubitril/valsartan ne...

journal_title：Current cardiology reports

authors： Fabris E,De Luca A,Vitrella G,Stolfo D,Masè M,Korcova R,Merlo M,Rakar S,Van't Hof AWJ,Kedhi E,Perkan A,Sinagra G

更新日期：2019-11-16 00:00:00

abstract：:Although advanced heart failure has been considered the main indication for heart transplantation, the increasing number of candidates and shortage of organs for transplantation, with accumulating waiting lists, has originated another look into more conventional surgery, previously considered of prohibitive risk. In f...

journal_title：Current cardiology reports

authors： Ferrão de Oliveira J,Antunes MJ

更新日期：2004-05-01 00:00:00

abstract：:Primary aldosteronism with a prevalence of 8 % of hypertension and 20 % of pharmacologically resistant hypertension is the most common secondary cause of hypertension. Yet, the diagnosis is missed in the vast majority of patients. Current clinical practice guidelines recommend screening for primary aldosteronism in pa...

journal_title：Current cardiology reports

authors： Carey RM

更新日期：2016-10-01 00:00:00