The Biological Mechanisms of Action of Cardiac Progenitor Cell Therapy.

abstract：:Cardiovascular mortality continues to be high and events continue to occur in patients taking antiplatelet medications. Aspirin and clopidogrel have become integral parts of management in patients with coronary artery disease and after percutaneous angioplasty. However, the platelet responses to aspirin and clopidogre...

journal_title：Current cardiology reports

authors： Guthikonda S,Lev EI,Kleiman NS

更新日期：2005-07-01 00:00:00

abstract：:Although advanced heart failure has been considered the main indication for heart transplantation, the increasing number of candidates and shortage of organs for transplantation, with accumulating waiting lists, has originated another look into more conventional surgery, previously considered of prohibitive risk. In f...

journal_title：Current cardiology reports

authors： Ferrão de Oliveira J,Antunes MJ

更新日期：2004-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Cardiovascular disease is a leading cause of morbidity and mortality worldwide and is the focus of extensive biomedical research. Large genetic consortia combining data from many traditional prospective cohort and ascertained case-control study designs have facilitated the discovery of genetic associa...

journal_title：Current cardiology reports

authors： Small AM,O'Donnell CJ,Damrauer SM

更新日期：2018-03-08 00:00:00

abstract：:Several next generation sequencing platforms allow for a DNA-to-diagnosis protocol to identify the molecular basis of monogenic dyslipidemias. However, recent reports of the application of whole genome or whole exome sequencing in families with severe dyslipidemias have largely identified genetic variants in known lip...

journal_title：Current cardiology reports

authors： Farhan SM,Hegele RA

更新日期：2014-07-01 00:00:00

abstract：:Synthesized as an antianginal compound 40 years ago, amiodarone has emerged as a uniquely effective antiarrhythmic compound in recent years. It has numerous properties, the most prominent being the ability to lengthen repolarization in the atria and ventricles associated with bradycardia without the significant potent...

journal_title：Current cardiology reports

authors： Singh BN

更新日期：2006-09-01 00:00:00

abstract：:Although clinical evidence indicates that many of the electrophysiologic and functional changes associated with atrial fibrillation (AF) can be reversed by maintaining normal sinus rhythm (NSR), a series of large-scale randomized trials failed to demonstrate that this strategy provides a survival advantage. These stud...

journal_title：Current cardiology reports

authors： Zimetbaum P

更新日期：2006-09-01 00:00:00

abstract：PURPOSE OF REVIEW:This is an in-depth review on the mechanism of action, clinical utility, and drug-drug interactions of colchicine in the management of pericardial disease. RECENT FINDINGS:Recent evidence about therapeutic targets on pericarditis has demonstrated that NALP3 inflammasome blockade is the cornerstone in...

journal_title：Current cardiology reports

authors： Schenone AL,Menon V

更新日期：2018-06-14 00:00:00

abstract：:A number of neurohormones and cytokines are activated in heart failure and their activity is related to the progression of heart failure. Inhibiting the deleterious effects of the activated sympathetic and the renin-angiotensin-aldosterone systems with b-blockers, angiotensin-converting enzyme inhibitors, and aldoster...

journal_title：Current cardiology reports

authors： Anand IS

更新日期：2004-05-01 00:00:00

abstract：:Heart failure is a major public health concern that is frequently complicated by ventricular arrhythmias. Sustained ventricular tachycardia is associated with an increased risk for progressive heart failure and sudden death. We summarize the current management strategies for ventricular tachycardia in heart failure pa...

journal_title：Current cardiology reports

authors： Fong MW,Grazette L,Cesario D,Cao M,Saxon L

更新日期：2011-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Ocular perfusion pressure (OPP) is defined as the difference between BP and intraocular pressure (IOP). With low BP comes low OPP and resultant ischemic damage to the optic nerve, leading to glaucoma progression. The purpose of this article is to review the literature on BP as it relates to glaucoma a...

journal_title：Current cardiology reports

authors： Levine RM,Yang A,Brahma V,Martone JF

更新日期：2017-09-19 00:00:00

abstract：:Cardiac resynchronization therapy (CRT) is a proven treatment for heart failure and requires the implantation of a left ventricular (LV) lead, usually placed in a tributary of the coronary sinus. Encouraged by the fact that approximately 30 % of the patients receiving CRT do not benefit from this therapy, LV endocardi...

journal_title：Current cardiology reports

authors： Bordachar P,Ploux S,Lumens J

更新日期：2012-10-01 00:00:00

abstract：PURPOSE OF REVIEW:There is a broad spectrum of coronary artery anomalies that cardiologists may encounter either incidentally or during evaluation for cardiac symptoms. These anomalies include anomalous coronary arteries arising from the opposite sinus of Valsalva (ACAOS), coronary fistulae, and coronary artery aneurys...

journal_title：Current cardiology reports

authors： Kochar A,Kiefer T

更新日期：2017-05-01 00:00:00

abstract：:Aortic stenosis (AS) is the most common primary valve disorder in the elderly with an increasing prevalence. It is increasingly clear that it is also a disease of the left ventricle (LV) rather than purely the aortic valve. The transition from left ventricular hypertrophy to fibrosis results in the eventual adverse ef...

journal_title：Current cardiology reports

authors： Badiani S,van Zalen J,Treibel TA,Bhattacharyya S,Moon JC,Lloyd G

更新日期：2016-08-01 00:00:00

abstract：:Heart failure management is complex and costly. Genetic variations that alter drug absorption, metabolism, and receptor-ligand interactions have the potential to modify drug response and safety. Evidence shows that genetic factors interact with numerous heart failure medications, including vasodilators, beta blockers,...

journal_title：Current cardiology reports

authors： Lowes BD,Buttrick PM

更新日期：2008-05-01 00:00:00

abstract：:This review focuses on the use of bivalirudin as a replacement anticoagulant for heparin in patients undergoing percutaneous coronary intervention, or who are being treated for unstable angina pectoris, ST-elevation, or non-ST-elevation myocardial infarction. Potential advantages of bivalirudin include a lack of depen...

journal_title：Current cardiology reports

authors： Bates ER

更新日期：2001-09-01 00:00:00

abstract：PURPOSE OF REVIEW:This review provides an update on rheumatic mitral stenosis. Acute rheumatic fever (RF), the sequela of group A β-hemolytic streptococcal infection, is the major etiology for mitral stenosis (MS). RECENT FINDINGS:While the incidence of acute RF in the Western world had substantially declined over the...

journal_title：Current cardiology reports

authors： Wunderlich NC,Dalvi B,Ho SY,Küx H,Siegel RJ

更新日期：2019-02-28 00:00:00

abstract：PURPOSE OF REVIEW:Transcatheter aortic valve replacement (TAVR) has developed into an important alternative to surgical aortic valve replacement (SAVR) for patients with severe aortic stenosis (AS). Adjuvant antithrombotic therapies are commonly used during and after TAVR to decrease the risk of valve thrombosis and th...

journal_title：Current cardiology reports

authors： O'Malley RG,Mahaffey KW,Fearon WF

更新日期：2017-05-01 00:00:00

abstract：:Significant progress in research has been made in the areas of sex-specific aspects of cardiovascular disease. Despite these advances, coronary artery disease (CAD) is the leading cause of death of women in the Western world. Over the past decade, the focused research on women at risk for ischemic heart disease has he...

journal_title：Current cardiology reports

authors： Phillips LM,Mieres JH

更新日期：2010-03-01 00:00:00

abstract：PURPOSE OF REVIEW:This review discusses the complementary roles of echocardiography and cardiac magnetic resonance in the diagnosis and management of patients with hypertrophic cardiomyopathy (HCM). RECENT FINDINGS:Imaging using novel echocardiographic techniques and cardiac magnetic resonance (CMR) imaging in HCM has...

journal_title：Current cardiology reports

authors： Hindieh W,Chan R,Rakowski H

更新日期：2017-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Acute pulmonary embolism is a major cause of morbidity and mortality in the USA and throughout the world. This review will summarize recent developments in short- and long-term mortality risk assessment after an acute pulmonary embolism. RECENT FINDINGS:Recent guidelines have emphasized risk stratifi...

journal_title：Current cardiology reports

authors： Gupta R,Fortman DD,Morgenstern DR,Cooper CJ

更新日期：2018-10-11 00:00:00

abstract：PURPOSE OF REVIEW:To discuss the mechanisms of iron regulation in the brain and the pathophysiological role of deregulation of iron homeostasis following a stroke, and to review existing evidence supporting the potential role of iron chelators in the treatment of ischemic and hemorrhagic stroke. RECENT FINDINGS:In rec...

journal_title：Current cardiology reports

authors： Hanafy KA,Gomes JA,Selim M

更新日期：2019-03-04 00:00:00

abstract：:Diastolic dysfunction in patients with hypertension may present as asymptomatic findings on noninvasive testing, or as fulminant pulmonary edema, despite normal left ventricular systolic function. Up to 40% of hypertensive patients presenting with clinical signs of congestive heart failure have normal systolic left ve...

journal_title：Current cardiology reports

authors： Phillips RA,Diamond JA

更新日期：2001-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Although rare, sudden cardiac death (SCD) in the young is a tragic event, having a dramatic impact upon all involved. The psychosocial burden associated with SCD can leave friends, families, and entire communities bereft. With only limited evidence to describe the volatile emotional reactions associat...

journal_title：Current cardiology reports

authors： Grubic N,Puskas J,Phelan D,Fournier A,Martin LJ,Johri AM

更新日期：2020-10-10 00:00:00

abstract：:Over the past decade, catheter based treatments of an increasing variety of cardiac diseases have expanded dramatically. These advancements became available through new developments and improvements in available devices, as well as increasing expertise of operators. However, arguably it is the innovation and progress ...

journal_title：Current cardiology reports

authors： Perk G,Kronzon I

更新日期：2013-03-01 00:00:00

abstract：PURPOSE OF REVIEW:This review presents the current available evidence of the effects of several dietary patterns on atherosclerotic cardiovascular disease (ASCVD) risk in patients with type 2 diabetes (T2D). RECENT FINDINGS:Evidence demonstrates improvements in cardiovascular risk factors with some dietary patterns in...

journal_title：Current cardiology reports

authors： Liday C,Kirkpatrick C

更新日期：2019-10-17 00:00:00

abstract：:Despite a vast body of research on antithrombotic therapy for patients with cardiac disease, there are few clinical settings where robust evidence of their benefit exists. Patients with heart failure often have vascular disease and atrial fibrillation contributing to their poor prognosis. For patients with heart failu...

journal_title：Current cardiology reports

authors： Cleland JG,Mumtaz S,Cecchini L

更新日期：2012-06-01 00:00:00

abstract：:The excess risk of hypertension in black Americans continues to be a major health concern. Although there is considerable information regarding these disease trends, much of the major underpinnings of the etiology of hypertension remain unclear. The excess mortality in blacks due to heart disease, renal failure, and s...

journal_title：Current cardiology reports

authors： Nesbitt SD

更新日期：2004-11-01 00:00:00

abstract：:Hypertension in patients with renovascular disease poses a major clinical challenge. Renal arterial disease accelerates hypertension by activation of multiple pressor systems. Although younger individuals with fibromuscular lesions often respond well to angioplasty with minor associated risks, care must be taken in ca...

journal_title：Current cardiology reports

authors： Textor SC

更新日期：2007-11-01 00:00:00

abstract：PURPOSE OF REVIEW:This study aims to describe the current state of telestroke clinical applications and policies, in addition to key technical and operational aspects of the telemedicine practice. RECENT FINDINGS:Delivery of telestroke services for neurovascular care expanded from the intravenous alteplase decision an...

journal_title：Current cardiology reports

authors： Dumitrascu OM,Demaerschalk BM

更新日期：2017-09-01 00:00:00

abstract：:Increasing barriers to medical device innovation in the United States including constrained financial resources and rising research costs require that physicians take on greater involvement in medical device development, evaluation, and regulatory processes. Such involvement requires that physicians understand basic a...

journal_title：Current cardiology reports

authors： Sastry A

更新日期：2014-01-01 00:00:00