Abstract：
:Hypertension in patients with renovascular disease poses a major clinical challenge. Renal arterial disease accelerates hypertension by activation of multiple pressor systems. Although younger individuals with fibromuscular lesions often respond well to angioplasty with minor associated risks, care must be taken in cases of complex vascular anomalies, such as renal artery aneurysms. More than 85% of patients referred for revascularization have atherosclerotic renal artery stenosis; most are older patients with preexisting hypertension, diabetes, and vascular disease. The benefits of stent revascularization in this group are controversial. Antihypertensive therapy works best with drugs that block the renin-angiotensin system; however, most patients require multiple agents. Detailed analysis of the literature and small prospective trials failed to identify major benefits with renal artery angioplasty as compared with intensive drug therapy. The CORAL study and others seek to randomly assign subjects with high-grade renovascular lesions to optimal medical management with and without stenting.
journal_name
Curr Cardiol Repjournal_title
Current cardiology reportsauthors
Textor SCdoi
10.1007/BF02938389subject
Has Abstractpub_date
2007-11-01 00:00:00pages
453-61issue
6eissn
1523-3782issn
1534-3170journal_volume
9pub_type
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更新日期：2008-09-01 00:00:00
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更新日期：2016-05-01 00:00:00
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更新日期：2015-12-01 00:00:00
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更新日期：2019-03-04 00:00:00
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更新日期：2006-02-01 00:00:00
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pub_type： 杂志文章,评审
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更新日期：2002-01-01 00:00:00
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更新日期：2011-04-01 00:00:00
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更新日期：2001-07-01 00:00:00
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更新日期：2018-03-23 00:00:00
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journal_title：Current cardiology reports
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更新日期：2020-09-15 00:00:00
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更新日期：2014-01-01 00:00:00
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更新日期：2014-11-01 00:00:00
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更新日期：2014-08-01 00:00:00
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journal_title：Current cardiology reports
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更新日期：2007-04-01 00:00:00
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journal_title：Current cardiology reports
pub_type： 杂志文章,评审
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更新日期：2016-07-01 00:00:00
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journal_title：Current cardiology reports
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更新日期：2020-08-08 00:00:00
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journal_title：Current cardiology reports
pub_type： 杂志文章,评审
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更新日期：2007-09-01 00:00:00
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