Abstract:
:Biventricular pacing (cardiac resynchronization therapy ) has been shown to be a very effective therapy for patients with heart failure and dyssynchrony, with improved survival now shown in a recent trial. Electrical dyssynchrony, usually quantified by the duration of the QRS complex, is distinct from mechanical dyssynchrony. Intraventricular mechanical dyssynchrony is most commonly manifest by decreased septal work with concomitant early lateral wall prestretch and subsequent inefficient late contraction. Intraventricular dyssynchrony appears to be more predictive of response to CRT than interventricular dyssynchrony. Mechanical left ventricular dyssynchrony also is associated with regional molecular derangements in connexin-43, stress response kinases, and tumor necrosis factor-alpha. These molecular derangements may lead to abnormalities in conduction velocity and action potential duration, which may predispose to ventricular arrhythmia. Biventricular pacing corrects abnormal regional wall stresses and results in electrical, mechanical, and molecular left ventricular remodeling.
journal_name
Curr Cardiol Repjournal_title
Current cardiology reportsauthors
Bilchick KC,Helm RH,Kass DAdoi
10.1007/BF02938362subject
Has Abstractpub_date
2007-09-01 00:00:00pages
358-65issue
5eissn
1523-3782issn
1534-3170journal_volume
9pub_type
杂志文章,评审abstract::Deformation imaging by tissue Doppler imaging (TDI) and speckle-tracking echocardiography (STE) are emerging clinical methods. TDI- and STE-derived parameters, such as myocardial strain and strain rate, as well as torsion and twist, provide detailed information about myocardial function and are associated with cardiov...
journal_title:Current cardiology reports
pub_type: 杂志文章,评审
doi:10.1007/s11886-015-0568-x
更新日期:2015-03-01 00:00:00
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journal_title:Current cardiology reports
pub_type: 杂志文章,评审
doi:10.1007/s11886-004-0048-1
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journal_title:Current cardiology reports
pub_type: 杂志文章,评审
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更新日期:2004-05-01 00:00:00
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journal_title:Current cardiology reports
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doi:10.1007/s11886-018-1024-5
更新日期:2018-09-01 00:00:00
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journal_title:Current cardiology reports
pub_type: 杂志文章,评审
doi:10.1007/s11886-010-0131-8
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journal_title:Current cardiology reports
pub_type: 杂志文章,评审
doi:10.1007/s11886-011-0202-5
更新日期:2011-10-01 00:00:00
abstract::Frailty is increasingly recognized in older adults with cardiovascular disease, particularly in those with heart failure (HF). A growing body of evidence has shown that frailty has a negative effect on survival, hospitalizations, disability, and quality of life. Beyond frailty, additional domains captured by a compreh...
journal_title:Current cardiology reports
pub_type: 杂志文章,评审
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更新日期:2015-11-01 00:00:00
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journal_title:Current cardiology reports
pub_type: 杂志文章,评审
doi:10.1007/s11886-020-01284-3
更新日期:2020-05-19 00:00:00
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journal_title:Current cardiology reports
pub_type: 杂志文章,评审
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更新日期:2016-06-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2019-11-25 00:00:00
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journal_title:Current cardiology reports
pub_type: 杂志文章
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更新日期:2000-05-01 00:00:00
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journal_title:Current cardiology reports
pub_type: 杂志文章
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更新日期:2004-03-01 00:00:00
abstract::The article title in the original publication contains a mistake. ...
journal_title:Current cardiology reports
pub_type: 已发布勘误
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更新日期:2020-09-08 00:00:00
abstract:PURPOSE OF REVIEW:To analyze the current state of the art of functional mitral regurgitation (FMR) treatment. RECENT FINDINGS:The first-line treatment of severe FMR consists of guideline medical therapy (GMT) and resynchronization therapy when indicated; the impact of new medical therapies like sacubitril/valsartan ne...
journal_title:Current cardiology reports
pub_type: 杂志文章,评审
doi:10.1007/s11886-019-1221-x
更新日期:2019-11-16 00:00:00
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journal_title:Current cardiology reports
pub_type: 杂志文章,评审
doi:10.1007/s11886-014-0507-2
更新日期:2014-07-01 00:00:00
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journal_title:Current cardiology reports
pub_type: 杂志文章,评审
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更新日期:2016-01-01 00:00:00
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journal_title:Current cardiology reports
pub_type: 杂志文章,评审
doi:10.1007/s11886-000-0082-6
更新日期:2000-07-01 00:00:00
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journal_title:Current cardiology reports
pub_type: 杂志文章,评审
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更新日期:2019-02-28 00:00:00
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journal_title:Current cardiology reports
pub_type: 杂志文章,评审
doi:10.1007/s11886-018-1023-6
更新日期:2018-07-26 00:00:00
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journal_title:Current cardiology reports
pub_type: 杂志文章,评审
doi:10.1007/s11886-010-0102-0
更新日期:2010-05-01 00:00:00
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journal_title:Current cardiology reports
pub_type: 杂志文章,评审
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更新日期:2016-06-01 00:00:00
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journal_title:Current cardiology reports
pub_type: 杂志文章,评审
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更新日期:2018-03-08 00:00:00
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journal_title:Current cardiology reports
pub_type: 杂志文章,评审
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更新日期:2017-06-01 00:00:00
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journal_title:Current cardiology reports
pub_type: 杂志文章,评审
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更新日期:2012-04-01 00:00:00
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journal_title:Current cardiology reports
pub_type: 杂志文章,评审
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更新日期:2004-07-01 00:00:00
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journal_title:Current cardiology reports
pub_type: 杂志文章,评审
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更新日期:2019-07-27 00:00:00
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journal_title:Current cardiology reports
pub_type: 杂志文章,评审
doi:10.1007/s11886-016-0713-1
更新日期:2016-04-01 00:00:00
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journal_title:Current cardiology reports
pub_type: 杂志文章,评审
doi:10.1007/s11886-017-0927-x
更新日期:2017-09-19 00:00:00
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journal_title:Current cardiology reports
pub_type: 杂志文章,评审
doi:10.1007/s11886-016-0774-1
更新日期:2016-10-01 00:00:00
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journal_title:Current cardiology reports
pub_type: 杂志文章,评审
doi:10.1007/s11886-020-01306-0
更新日期:2020-07-07 00:00:00