Aortic valve disease: current recommendations.

abstract：PURPOSE OF REVIEW:Monoclonal antibodies that inhibit proprotein convertase subtilisin/kexin type 9 (PCSK9) have emerged as a novel approach to low-density lipoprotein cholesterol (LDL-C) lowering. The potential role of PCSK9 inhibitors in clinical practice will be reviewed. RECENT FINDINGS:Clinical trials have demonst...

journal_title：Current cardiology reports

authors： King P,Nicholls SJ

更新日期：2017-08-01 00:00:00

abstract：:Selective coronary angiography was originally performed through open brachial arteriotomy. Thereafter, the percutaneous Seldinger technique and the use of preformed Judkins-type catheters popularized the femoral approach. More recently, after the first report of successful coronary angiography by the transradial appro...

journal_title：Current cardiology reports

authors： Franchi E,Marino P,Biondi-Zoccai GG,De Luca G,Vassanelli C,Agostoni P

更新日期：2009-09-01 00:00:00

abstract：:Recent advances in clinical cardiac SPECT instrumentation are reviewed from a systems perspective. New hardware technologies include pixelated scintillator and semiconductor detector elements; photodetectors such as position-sensitive photomultiplier tubes (PSPMT), avalanche photodiodes (APD) and silicon photomultipli...

journal_title：Current cardiology reports

authors： Smith MF

更新日期：2013-08-01 00:00:00

abstract：PURPOSE OF REVIEW:The goal was to evaluate published data on the incidence, diagnosis, and management of symptomatic combined mitral and aortic valvular disease. Furthermore, to identify the role of treatment using contemporary transcatheter techniques. RECENT FINDINGS:Up to a quarter of symptomatic adult valvular dis...

journal_title：Current cardiology reports

authors： De Palma R,O'Sullivan CJ,Settergren M

更新日期：2019-09-13 00:00:00

abstract：:Aortic valve replacement can produce dramatic benefit in the setting of aortic stenosis. The potential for morbidity and mortality associated with thoracotomy, cardiopulmonary bypass, and aortotomy has fostered a search for alternatives. Early experience with transcatheter endovascular aortic valve implantation demons...

journal_title：Current cardiology reports

authors： Webb JG

更新日期：2008-03-01 00:00:00

abstract：:Deformation imaging by tissue Doppler imaging (TDI) and speckle-tracking echocardiography (STE) are emerging clinical methods. TDI- and STE-derived parameters, such as myocardial strain and strain rate, as well as torsion and twist, provide detailed information about myocardial function and are associated with cardiov...

journal_title：Current cardiology reports

authors： Opdahl A,Helle-Valle T,Skulstad H,Smiseth OA

更新日期：2015-03-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of the present manuscript is to review the latest advancements of radionuclide molecular imaging in the diagnosis and prognosis of individuals with cardiac amyloidosis. RECENT FINDINGS:99mTechnetium labeled bone tracer scintigraphy had been known to image cardiac amyloidosis, since the 1980s;...

journal_title：Current cardiology reports

authors： Bravo PE,Dorbala S

更新日期：2017-07-01 00:00:00

abstract：:A number of reports demonstrate the importance of serum triglyceride values in predicting the clinical onset of vascular disease. However, adjustment for measurements highly correlated with triglyceride (TG) levels, such as history of diabetes, body mass index, and high-density lipoprotein cholesterol (HDL-C), lessen ...

journal_title：Current cardiology reports

authors： Sprecher DL

更新日期：2001-09-01 00:00:00

abstract：:Cardiac implantable electronic device (CIED) infections are complex medical problems that are increasingly encountered. They are associated with significant morbidity and mortality with tremendous economic cost. The current review will emphasize the prevention, diagnosis, and treatment of this clinical entity using th...

journal_title：Current cardiology reports

authors： Leung S,Danik S

更新日期：2016-06-01 00:00:00

abstract：:A natural extension of current imaging paradigms for diagnosing coronary artery disease may well be the integration of CT with myocardial perfusion single-photon CT (SPECT). Although there is a wealth of clinical information regarding the utility of SPECT, the value of CT in the cardiology arena has only recently been...

journal_title：Current cardiology reports

authors： Mahmarian JJ

更新日期：2007-04-01 00:00:00

abstract：:There are a number of limitations associated with conventional mapping for ablation of ventricular tachycardia (VT) in ischemic heart disease, such as the high recurrence rates after initially successful ablation. The development of a noncontact mapping system capable of producing high-resolution isopotential maps of ...

journal_title：Current cardiology reports

authors： Chow AW,Schilling RJ,Peters NS,Davies DW

更新日期：2000-11-01 00:00:00

abstract：:Aldosterone is the principal circulating mineralocorticoid in humans, and aldosterone synthesis normally occurs in the face of volume depletion and renin stimulation. In primary and secondary aldosteronism, aldosterone synthesis continues despite volume expansion and causes hypertension. Other steroid hormones that ar...

journal_title：Current cardiology reports

authors： Auchus RJ

更新日期：2005-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Ebstein's anomaly (EA) is a rare, but complex form of congenital heart disease consisting of a right ventricular myopathy and morphologic tricuspid valve disease leading to a high incidence of right ventricular dysfunction and arrhythmias. This review offers an updated overview of the current understa...

journal_title：Current cardiology reports

authors： Possner M,Gensini FJ,Mauchley DC,Krieger EV,Steinberg ZL

更新日期：2020-10-09 00:00:00

abstract：PURPOSE OF REVIEW:This review aims to clarify the cardiovascular risk of white coat hypertension (WCH). RECENT FINDINGS:Cardiovascular risk of WCH has been evaluated in multiple meta-analyses and population-based studies. International Database on Ambulatory Blood Pressure Monitoring in Relation to Cardiovascular Outc...

journal_title：Current cardiology reports

authors： Abolbashari M

更新日期：2018-03-08 00:00:00

abstract：PURPOSE OF REVIEW:The present article reviews the pathophysiology of cardiac sympathetic denervation, the principles of positron emission tomography (PET) imaging of the sympathetic innervation of the heart and its potential clinical role, based on current and expected future evidence. RECENT FINDINGS:Imaging of cardi...

journal_title：Current cardiology reports

authors： van der Bijl P,Knuuti J,Delgado V,Bax JJ

更新日期：2020-11-27 00:00:00

abstract：PURPOSE OF REVIEW:The two most common types of cardiac amyloidosis are caused by fibril deposits of immunoglobulin light chains (AL) and transthyretin (TTR), each with distinct prognosis and clinical management. Cardiac amyloidosis is under-recognized among heart failure patients with preserved ejection fraction (HFpEF...

journal_title：Current cardiology reports

authors： Chen W,Ton VK,Dilsizian V

更新日期：2018-03-08 00:00:00

abstract：PURPOSE OF REVIEW:To review methodological and logistical aspects of CT myocardial perfusion, current clinical evidence and possible future directions, with specific focus on use in patients with coronary artery disease (CAD). RECENT FINDINGS:CT myocardial perfusion imaging may be performed as an add-on to standard co...

journal_title：Current cardiology reports

authors： Kofoed KF,Sørgaard MH,Linde JJ

更新日期：2017-10-25 00:00:00

abstract：PURPOSE OF REVIEW:To review the clinical evidence on the use of percutaneous coronary intervention (PCI) revascularization options in left main (LM) disease in comparison with coronary artery bypass graft (CABG). Coronary artery disease (CAD) involving the LM is associated with high morbidity and mortality. Though CABG...

journal_title：Current cardiology reports

authors： Nagarajarao HS,Ojha CP,Mulukutla V,Ibrahim A,Mares AC,Paul TK

更新日期：2020-02-08 00:00:00

abstract：:Over the past two decades, we have witnessed a large decrease in the death and complication rate of patients experiencing acute myocardial infarction (MI), due to our ability to restore blood flow to infarct-related arteries. Therapies include strategies to inhibit platelet function and induce fibrinolysis, and mechan...

journal_title：Current cardiology reports

authors： Maranian AM,Steinhubl SR

更新日期：2002-07-01 00:00:00

abstract：:Conventional algorithms and noninvasive imaging tests for the identification of stable, hemodynamically significant coronary artery disease offer little insight into the detection of potentially vulnerable and inflamed coronary plaques, those most likely to rupture and cause acute coronary syndromes. Positron emission...

journal_title：Current cardiology reports

authors： Rogers IS,Tawakol A

更新日期：2011-04-01 00:00:00

abstract：PURPOSE OF REVIEW:In this review, we summarise the evidence on the association between cardiovascular disease (CVD) and cognitive impairment and explore the role of the nitric oxide (NO) pathway as a causal mechanism. RECENT FINDINGS:Evidence from epidemiological studies suggests that the presence of CVD and its risk ...

journal_title：Current cardiology reports

authors： Stephan BCM,Harrison SL,Keage HAD,Babateen A,Robinson L,Siervo M

更新日期：2017-08-11 00:00:00

abstract：:Cardiovascular mortality continues to be high and events continue to occur in patients taking antiplatelet medications. Aspirin and clopidogrel have become integral parts of management in patients with coronary artery disease and after percutaneous angioplasty. However, the platelet responses to aspirin and clopidogre...

journal_title：Current cardiology reports

authors： Guthikonda S,Lev EI,Kleiman NS

更新日期：2005-07-01 00:00:00

abstract：:Diabetic patients who present with an acute coronary syndrome (ACS) have a particularly adverse prognosis, largely contributed by increased platelet reactivity and higher burden of disease severity. Diabetic patients with ACS derive a greater benefit from established therapies, particularly platelet-inhibiting therapi...

journal_title：Current cardiology reports

authors： Amin AP,Marso SP

更新日期：2010-07-01 00:00:00

abstract：:Aortic stenosis affects many people worldwide with a significant impact on morbidity and mortality with uncorrected, symptomatic aortic valve stenosis carrying mortality of 50% at one year. Degenerative calcific pathology, the most common cause of aortic stenosis, increases in prevalence with age; estimated prevalence...

journal_title：Current cardiology reports

authors： Halim SA,Kiefer TL,Hughes GC,Hurwitz LM,Harrison JK

更新日期：2013-06-01 00:00:00

abstract：:Gut microbiota has been recently established to have a contributory role in the development of cardiometabolic disorders, such as atherosclerosis, obesity, and type 2 diabetes. Growing interest has focused on the modulation of gut microbiota as a therapeutic strategy in cardiovascular diseases and metabolic disorders....

journal_title：Current cardiology reports

authors： Miele L,Giorgio V,Alberelli MA,De Candia E,Gasbarrini A,Grieco A

更新日期：2015-12-01 00:00:00

abstract：:Beta-Adrenergic blockade is associated with a significant reduction in mortality in most patients with structural heart disease. Clinical trial data involving patients after myocardial infarction or with congestive heart failure demonstrate that a reduction in sudden death accounts for much of the observed mortality r...

journal_title：Current cardiology reports

authors： Reiter MJ

更新日期：2002-09-01 00:00:00

abstract：PURPOSE OF REVIEW:This article reviews the latest data on unprotected left main (ULM) percutaneous coronary intervention (PCI) versus coronary artery bypass graft (CABG) surgery, with a focus on the NOBLE and EXCEL trials. RECENT FINDINGS:In EXCEL trial, the primary endpoint at 3 years was 15.4% in the PCI group and 1...

journal_title：Current cardiology reports

authors： Taha Y,Patel RAG,Bagai J,Sachdeva R,Kumar G,Prasad A,Nathan S,Paul TK

更新日期：2019-03-18 00:00:00

abstract：PURPOSE OF REVIEW:To examine the utility and methods of coronary artery disease (CAD) assessment in patients with new-onset heart failure with reduced ejection fraction (HFrEF) of unclear etiology. Moreover, we sought to review the role and techniques of assessing myocardial viability to guide coronary revascularizatio...

journal_title：Current cardiology reports

authors： Kassab K,Kattoor AJ,Doukky R

更新日期：2020-07-06 00:00:00

abstract：:Statins are first line therapy for the prevention of cardiovascular disease (CVD). Only 30 %-70 % of high risk patients will attain standard low-density lipoprotein cholesterol targets. Patients with familial hypercholesterolemia and genetic mixed hyperlipidemias do not meet goals with standard therapy. Patients with ...

journal_title：Current cardiology reports

authors： Barnett J,Viljoen A,Wierzbicki AS

更新日期：2013-08-01 00:00:00

abstract：:Medical management of patients with atrial fibrillation (AF) at high risk for stroke is limited by problems of imperfect tools for assessment of thromboembolism and bleeding risks. Improved instruments, such as the CHA₂DS₂VASc and HAS-BLED risk stratification scores, have been incorporated into European practice guide...

journal_title：Current cardiology reports

authors： Broukhim M,Halperin JL

更新日期：2011-02-01 00:00:00