Functional Information in Coronary Artery Disease: The Case of Computed Tomography Myocardial Perfusion.

Abstract:

PURPOSE OF REVIEW:To review methodological and logistical aspects of CT myocardial perfusion, current clinical evidence and possible future directions, with specific focus on use in patients with coronary artery disease (CAD). RECENT FINDINGS:CT myocardial perfusion imaging may be performed as an add-on to standard coronary CT angiography (CCTA), to identify regions of myocardial hypoperfusion, at rest and during adenosine stress. The principle of measurement is well-validated in animal experimental models, and CT myocardial perfusion imaging has a high degree of concordance with already clinically available perfusion imaging methods. Combining CCTA and CT myocardial perfusion imaging increases the diagnostic accuracy to identify patients with CAD associated with ischemia. In patients suspected of CAD, CCTA frequently detects coronary atherosclerotic lesions, in which revascularization could be clinically beneficial. CT myocardial perfusion imaging may be helpful to identify coronary lesions associated with myocardial ischemia, and thus potentially suitable for coronary intervention.

journal_name

Curr Cardiol Rep

authors

Kofoed KF,Sørgaard MH,Linde JJ

doi

10.1007/s11886-017-0937-8

subject

Has Abstract

pub_date

2017-10-25 00:00:00

pages

126

issue

12

eissn

1523-3782

issn

1534-3170

pii

10.1007/s11886-017-0937-8

journal_volume

19

pub_type

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