Stroke prevention in the high-risk atrial fibrillation patient: Medical management.

abstract：:Beta-Adrenergic blockade is associated with a significant reduction in mortality in most patients with structural heart disease. Clinical trial data involving patients after myocardial infarction or with congestive heart failure demonstrate that a reduction in sudden death accounts for much of the observed mortality r...

journal_title：Current cardiology reports

authors： Reiter MJ

更新日期：2002-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Cardiovascular disease is a leading cause of morbidity and mortality worldwide and is the focus of extensive biomedical research. Large genetic consortia combining data from many traditional prospective cohort and ascertained case-control study designs have facilitated the discovery of genetic associa...

journal_title：Current cardiology reports

authors： Small AM,O'Donnell CJ,Damrauer SM

更新日期：2018-03-08 00:00:00

abstract：:Aortic stenosis (AS) is the most common primary valve disorder in the elderly with an increasing prevalence. It is increasingly clear that it is also a disease of the left ventricle (LV) rather than purely the aortic valve. The transition from left ventricular hypertrophy to fibrosis results in the eventual adverse ef...

journal_title：Current cardiology reports

authors： Badiani S,van Zalen J,Treibel TA,Bhattacharyya S,Moon JC,Lloyd G

更新日期：2016-08-01 00:00:00

abstract：:Lifestyle modification is primary in cardiovascular (CV) disease prevention. A major contribution is the Mediterranean diet (MedDiet), defined by two of seven components. Italian investigators determined a significant decrease in peripheral arterial disease of 56 % for a high score. Multiple specific CV risk factors a...

journal_title：Current cardiology reports

authors： Whayne TF Jr

更新日期：2014-01-01 00:00:00

abstract：:On page 2 of the original publication, in the section on TTR Silencers dosing of patisiran in the APOLLO study was stated as being given every 3 months; this is inaccurate as patisiran was dosed every 3 weeks in the APOLLO study. ...

journal_title：Current cardiology reports

authors： Hough A,Wearden J,de Almeida K,Kaiser S

更新日期：2020-09-28 00:00:00

abstract：:Exercise training is beneficial in healthy adults as well as patients with acquired cardiovascular disease such as coronary artery disease and heart failure. While a reduced exercise capacity is common in adults with congenital heart disease, it is not clear if these patients stand to benefit from exercise training or...

journal_title：Current cardiology reports

authors： Tutarel O,Gabriel H,Diller GP

更新日期：2013-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Assessing the cardiovascular risk associated with hypertriglyceridemia can be challenging due to frequent confounding conditions such as hypertension, diabetes mellitus, and hyperlipidemia. We sought to quantify this risk by examining several meta-analyses as well as subgroup analyses of previously pu...

journal_title：Current cardiology reports

authors： Evans MC,Stalam T,Miller M

更新日期：2018-07-10 00:00:00

abstract：PURPOSE OF REVIEW:Comprehensive discussion of alternative techniques in imaging coronary artery anomalies (CAAs) in different diagnostic scenarios. RECENT FINDINGS:At primary screening, intramural course essentially correlates with stenosis and clinical repercussion in some types of CAAs. Potential clinical aims in im...

journal_title：Current cardiology reports

authors： Angelini P

更新日期：2019-07-29 00:00:00

abstract：PURPOSE:This paper reviews the double-kiss crush (DK crush) technique in coronary artery bifurcation lesions. The technical aspects of the procedure and the clinical data supporting its use are summarized. RECENT FINDINGS:Randomized studies support the adoption of DK technique in complex bifurcation lesions for both l...

journal_title：Current cardiology reports

authors： Lynn BS,Hermiller JB

更新日期：2018-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Monoclonal antibodies that inhibit proprotein convertase subtilisin/kexin type 9 (PCSK9) have emerged as a novel approach to low-density lipoprotein cholesterol (LDL-C) lowering. The potential role of PCSK9 inhibitors in clinical practice will be reviewed. RECENT FINDINGS:Clinical trials have demonst...

journal_title：Current cardiology reports

authors： King P,Nicholls SJ

更新日期：2017-08-01 00:00:00

abstract：:Due to an increase in the number of patients with heart failure and ventricular arrhythmias, ventricular tachycardia ablation has a growing clinical role. Long-term success rates remain suboptimal and require creating a detailed electroanatomic map during the procedure to identify fibrotic areas responsible for arrhyt...

journal_title：Current cardiology reports

authors： Duell J,Dilsizian V,Smith M,Chen W,Dickfeld T

更新日期：2016-02-01 00:00:00

abstract：:The left atrial appendage (LAA) is the primary nonvalvular cause of cardioembolic stroke in patients with atrial fibrillation (AF). Warfarin and direct thrombin inhibitors such as dabigatran are presumed to prevent formation of LAA thrombus, and are first-line treatments to prevent ischemic stroke in AF. However, thes...

journal_title：Current cardiology reports

authors： Fuller CJ,Reisman M

更新日期：2011-04-01 00:00:00

abstract：PURPOSE OF REVIEW:To assess current management strategies for advanced heart failure in adults with congenital heart disease, including heart transplantation and mechanical circulatory support. RECENT FINDINGS:Current data demonstrate that adults with CHD generally experience higher short-term mortality after heart tr...

journal_title：Current cardiology reports

authors： Serfas JD,Patel PA,Krasuski RA

更新日期：2018-08-09 00:00:00

abstract：:Exercise intolerance in patients with chronic heart failure (CHF) shows no correlation to the degree of left ventricular dysfunction. This surprising finding has directed attention to peripheral changes in CHF: reduced endothelium-dependent vasodilation and altered skeletal muscle metabolism. Physical exercise trainin...

journal_title：Current cardiology reports

authors： Hambrecht R,Gielen S,Schuler G

更新日期：1999-05-01 00:00:00

abstract：:Heart failure management is complex and costly. Genetic variations that alter drug absorption, metabolism, and receptor-ligand interactions have the potential to modify drug response and safety. Evidence shows that genetic factors interact with numerous heart failure medications, including vasodilators, beta blockers,...

journal_title：Current cardiology reports

authors： Lowes BD,Buttrick PM

更新日期：2008-05-01 00:00:00

abstract：:Revascularization in stable ischemic heart disease (SIHD) is indicated in patients on optimal medical therapy with angina and/or demonstrable ischemia and a significant stenosis in one or more epicardial coronary arteries. Angiography alone, however, cannot accurately determine the hemodynamic significance of coronary...

journal_title：Current cardiology reports

authors： Parikh V,Agnihotri K,Kadavath S,Patel NJ,Abbott JD

更新日期：2016-04-01 00:00:00

abstract：:Hypertension in patients with renovascular disease poses a major clinical challenge. Renal arterial disease accelerates hypertension by activation of multiple pressor systems. Although younger individuals with fibromuscular lesions often respond well to angioplasty with minor associated risks, care must be taken in ca...

journal_title：Current cardiology reports

authors： Textor SC

更新日期：2007-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Several interrelated mechanisms promote the development of hypertension in obesity, often contributing to end organ damage including cardiovascular disease and chronic kidney disease. RECENT FINDINGS:The treatment of hypertension in obesity is complicated by a high prevalence of resistant hypertensio...

journal_title：Current cardiology reports

authors： Cohen JB

更新日期：2017-08-24 00:00:00

abstract：PURPOSE OF REVIEW:The aim of this report is to describe the main aspects of sex-related differences in non-ischemic dilated cardiomyopathies (DCM), focusing on chemotherapy-induced heart failure (HF) and investigating the possible therapeutic implications and clinical management applications in the era of personalized ...

journal_title：Current cardiology reports

authors： D'Amario D,Camilli M,Migliaro S,Canonico F,Galli M,Arcudi A,Montone RA,Borovac JA,Crea F,Savarese G

更新日期：2020-08-08 00:00:00

abstract：:Heart failure is becoming increasingly prevalent, and currently coronary artery disease (CAD) is the primary cause of left ventricular (LV) systolic dysfunction. A potential therapeutic option for patients with severe CAD and LV dysfunction is a strategy of revascularization. In this review, we summarize the available...

journal_title：Current cardiology reports

authors： Ghose T,Thompson RC

更新日期：2006-07-01 00:00:00

abstract：:Four non-communicable diseases-cardiovascular disease, chronic respiratory disease, diabetes mellitus, and cancer-account for over 60 % of all deaths globally. In recognition of this significant epidemic, the United Nations set forth a target of reducing the four major NCDs by 25 % by 2025. Cardiovascular disease alon...

journal_title：Current cardiology reports

authors： Dugani S,Gaziano TA

更新日期：2016-01-01 00:00:00

abstract：:Traditional transvenous approach for permanent cardiac pacing can be associated with significant acute and chronic complications related partly to either the insertion of transvenous lead or subcutaneous placement of pacemaker device. We summarize the current status of a novel self-contained leadless cardiac pacemaker...

journal_title：Current cardiology reports

authors： Neuzil P,Reddy VY

更新日期：2015-08-01 00:00:00

abstract：:Innate differences in gender physiology result in unique exposures, risk, and protection that are specific to women. Recognition and appreciation of these differences results in better treatment adaptations for women and better outcomes. Disparities between genders in the treatment of major cardiovascular risk factors...

journal_title：Current cardiology reports

authors： Jarvie JL,Foody JM

更新日期：2010-11-01 00:00:00

abstract：:Ischemic stroke threatens public health dramatically, and demographic changes promise to continue this epidemic. Although medical advances in risk factor modification, hypertensive control, and antiplatelet therapy have mitigated morbidity and mortality of cerebrovascular disease somewhat, stroke still costs billions ...

journal_title：Current cardiology reports

authors： Rajagopal V,Yadav JS

更新日期：2007-03-01 00:00:00

abstract：PURPOSE OF REVIEW:This review discusses the complementary roles of echocardiography and cardiac magnetic resonance in the diagnosis and management of patients with hypertrophic cardiomyopathy (HCM). RECENT FINDINGS:Imaging using novel echocardiographic techniques and cardiac magnetic resonance (CMR) imaging in HCM has...

journal_title：Current cardiology reports

authors： Hindieh W,Chan R,Rakowski H

更新日期：2017-09-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of low-density lipoprotein-cholesterol (LDL-C) lowering therapies is to safely achieve a consistent and long-term reduction in exposure of the vasculature to atherogenic lipoproteins in order to reduce the risk of atherosclerotic cardiovascular (CV) disease and the associated CV events, such a...

journal_title：Current cardiology reports

authors： Sinning D,Landmesser U

更新日期：2020-10-21 00:00:00

abstract：:The prevalence of atrial fibrillation increases significantly with age, affecting nearly 10 % of adults greater than 80 years of age. Complications from atrial fibrillation, including stroke, also increase with age. Medical therapy includes anticoagulation, ventricular rate control, and if symptoms persist, maintenanc...

journal_title：Current cardiology reports

authors： Stepanyan G,Gerstenfeld EP

更新日期：2013-10-01 00:00:00

abstract：:The excess risk of hypertension in black Americans continues to be a major health concern. Although there is considerable information regarding these disease trends, much of the major underpinnings of the etiology of hypertension remain unclear. The excess mortality in blacks due to heart disease, renal failure, and s...

journal_title：Current cardiology reports

authors： Nesbitt SD

更新日期：2004-11-01 00:00:00

abstract：:Congestive heart failure increasingly contributes to the overall morbidity and mortality associated with cardiovascular disease. Although significant advances in therapies allow patients to feel better and have improved functional status and survival, not all patients respond equally to these therapies. Moreover, for ...

journal_title：Current cardiology reports

authors： Chen GP,Caldwell JH

更新日期：2009-03-01 00:00:00

abstract：:In STEMI, primary PCI restores macrovascular coronary blood flow effectively but microvascular perfusion remains a challenge. Thrombus has the potential to embolize to the microvasculature limiting effective coronary blood flow. Thrombus burden is associated with a higher mortality and manual aspiration thrombectomy h...

journal_title：Current cardiology reports

authors： Alak A,Jolly SS

更新日期：2016-03-01 00:00:00