Management of carotid artery disease in the high-risk patient with emphasis on the SAPPHIRE study.

abstract：:Controlled clinical trials, performed in more than 13,000 patients, have consistently shown the beneficial effects of long-term beta-blocker therapy in patients with chronic heart failure. However, it is not clear whether this is a class effect or if it is specific only for some agents. Beneficial effects on the progn...

journal_title：Current cardiology reports

authors： Metra M,Nodari S,Boldi E,Dei Cas L

更新日期：2000-05-01 00:00:00

abstract：:Patients with pre-diabetes have a tenfold higher risk of developing Type 2 DM and a twofold higher risk of developing coronary heart disease compared to non-diabetics. Interventions targeted at those in an early stage of impaired glucose metabolism can delay or prevent diabetes. Effects of these interventions on cardi...

journal_title：Current cardiology reports

authors： Popp Switzer M,Elhanafi S,San Juan ZT

更新日期：2015-03-01 00:00:00

abstract：PURPOSE OF REVIEW:To review the clinical evidence on the use of percutaneous coronary intervention (PCI) revascularization options in left main (LM) disease in comparison with coronary artery bypass graft (CABG). Coronary artery disease (CAD) involving the LM is associated with high morbidity and mortality. Though CABG...

journal_title：Current cardiology reports

authors： Nagarajarao HS,Ojha CP,Mulukutla V,Ibrahim A,Mares AC,Paul TK

更新日期：2020-02-08 00:00:00

abstract：:Since 1971, the Fontan operation has been performed for the repair of single-ventricle physiology. This ingenious operation commits a single ventricle to the systemic circulation and takes advantage of cardiovascular and respiratory physiology to propel deoxygenated blood to the lungs, thus minimizing right-to-left sh...

journal_title：Current cardiology reports

authors： Aboulhosn J,Child JS

更新日期：2007-07-01 00:00:00

abstract：:Patients from racial and ethnic minorities experience higher mortality after cardiac surgery compared to white patients, both during the early postoperative phase as well as long term. A number of factors likely explain poor outcomes in black and minority patients, which include differences in biology, comorbid health...

journal_title：Current cardiology reports

authors： Khera R,Vaughan-Sarrazin M,Rosenthal GE,Girotra S

更新日期：2015-05-01 00:00:00

abstract：PURPOSE OF REVIEW:The present review aims to discuss the recent advances in surgical management of spontaneous intracerebral hemorrhage (ICH), safety and efficacy of minimally invasive surgical techniques, and the existing evidence supporting their use. RECENT FINDINGS:Newer surgical techniques, collectively referred ...

journal_title：Current cardiology reports

authors： Bhatia K,Hepburn M,Ziu E,Siddiq F,Qureshi AI

更新日期：2018-10-11 00:00:00

abstract：:Recent advances in clinical cardiac SPECT instrumentation are reviewed from a systems perspective. New hardware technologies include pixelated scintillator and semiconductor detector elements; photodetectors such as position-sensitive photomultiplier tubes (PSPMT), avalanche photodiodes (APD) and silicon photomultipli...

journal_title：Current cardiology reports

authors： Smith MF

更新日期：2013-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Acute pulmonary embolism is a major cause of morbidity and mortality in the USA and throughout the world. This review will summarize recent developments in short- and long-term mortality risk assessment after an acute pulmonary embolism. RECENT FINDINGS:Recent guidelines have emphasized risk stratifi...

journal_title：Current cardiology reports

authors： Gupta R,Fortman DD,Morgenstern DR,Cooper CJ

更新日期：2018-10-11 00:00:00

abstract：:Noninvasive cardiac imaging techniques have made a striking impact on the evaluation and management of pericardial disorders. Two-dimensional and Doppler echocardiography are the methods of choice in the evaluation of pericardial effusion and cardiac tamponade. Magnetic resonance imaging, computed tomography, and tran...

journal_title：Current cardiology reports

authors： Karia DH,Xing YQ,Kuvin JT,Nesser HJ,Pandian NG

更新日期：2002-01-01 00:00:00

abstract：:Significant progress in research has been made in the areas of sex-specific aspects of cardiovascular disease. Despite these advances, coronary artery disease (CAD) is the leading cause of death of women in the Western world. Over the past decade, the focused research on women at risk for ischemic heart disease has he...

journal_title：Current cardiology reports

authors： Phillips LM,Mieres JH

更新日期：2010-03-01 00:00:00

abstract：:Thrombolytic therapy aims to achieve rapid and sustained infarct-related artery patency, although this results in a procoagulant state. Heparin has limitations as an antithrombin agent, which has led to clinical investigation of alternative agents. Direct thrombin inhibitors, as adjuncts to thrombolytic therapy, have ...

journal_title：Current cardiology reports

authors： French JK,White HD

更新日期：1999-09-01 00:00:00

abstract：:There has been considerable attention in recent years to the intriguing hypothesis that coronary heart disease and other atherosclerotic diseases may be caused by infection with pathogens such as Chlamydia pneumoniae, Helicobacter pylori, and cytomegalovirus. Supporting this hypothesis are studies that localize bacter...

journal_title：Current cardiology reports

authors： O'Donnell CJ,Levy D

更新日期：2000-07-01 00:00:00

abstract：:Hypertension in children and adolescents is becoming a greater problem in the developed world. Although traditionally thought of as usually secondary to renal, vascular, or endocrine causes, primary hypertension is becoming the most common form seen in childhood. This changing epidemiology is related to the recent obe...

journal_title：Current cardiology reports

authors： Samuels J,Bell C,Samuel J,Swinford R

更新日期：2015-12-01 00:00:00

abstract：:Therapy to prevent deep venous thrombosis (DVT) and pulmonary embolism remains essential for inpatients, despite short periods of bedrest and hospitalization. Although most available data pertain to surgical patients, subgroups of medical patients are at moderate, high, and very high risk for DVT. These include patien...

journal_title：Current cardiology reports

authors： Shively BK

更新日期：2001-01-01 00:00:00

abstract：:Randomized clinical trials have established that lipid- lowering pharmacologic therapy can substantially reduce morbidity and mortality in patients with known coronary artery disease (CAD). Researchers are now working to define the role of lipid-lowering agents in the primary prevention of CAD to extend their benefit ...

journal_title：Current cardiology reports

authors： Nass CM,Wiviott SD,Allen JK,Post WS,Blumenthal aR

更新日期：2000-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Several interrelated mechanisms promote the development of hypertension in obesity, often contributing to end organ damage including cardiovascular disease and chronic kidney disease. RECENT FINDINGS:The treatment of hypertension in obesity is complicated by a high prevalence of resistant hypertensio...

journal_title：Current cardiology reports

authors： Cohen JB

更新日期：2017-08-24 00:00:00

abstract：PURPOSE OF REVIEW:Congenital heart disease is the most common birth defect and acquired heart disease is the leading cause of death in adults. Understanding the mechanisms that drive cardiomyocyte proliferation and differentiation has the potential to advance the understanding and potentially the treatment of different...

journal_title：Current cardiology reports

authors： Yester JW,Kühn B

更新日期：2017-02-01 00:00:00

abstract：:Percutaneous coronary intervention (PCI) of multivessel and/or left main stem disease have been shown to be potentially legitimate revascularization alternatives in appropriately selected patients. Risk stratification is an important component in guiding patients to identify the most appropriate revascularization moda...

journal_title：Current cardiology reports

authors： Farooq V,Brugaletta S,Serruys PW

更新日期：2011-10-01 00:00:00

abstract：:The long QT syndrome (LQTS) and the Brugada syndrome (BrS) are the most common genetic causes of malignant ventricular arrhythmias and sudden cardiac death in young patients with normal cardiac morphology. To date, more than 250 different mutations in seven genes have been identified as causing LQTS, whereas the only ...

journal_title：Current cardiology reports

authors： Goldenberg I,Moss AJ,Zareba W

更新日期：2005-09-01 00:00:00

abstract：:Echocardiography is the most common noninvasive tool used in assessing cardiac masses. Real-time three-dimensional echocardiography expands the diagnostic capabilities of cardiac ultrasound in assessing the location, composition, size, and relationship to other structures of cardiac masses. The improved characterizati...

journal_title：Current cardiology reports

authors： Plana JC

更新日期：2009-05-01 00:00:00

abstract：PURPOSE OF REVIEW:The goal was to evaluate published data on the incidence, diagnosis, and management of symptomatic combined mitral and aortic valvular disease. Furthermore, to identify the role of treatment using contemporary transcatheter techniques. RECENT FINDINGS:Up to a quarter of symptomatic adult valvular dis...

journal_title：Current cardiology reports

authors： De Palma R,O'Sullivan CJ,Settergren M

更新日期：2019-09-13 00:00:00

abstract：:Imaging with radionuclides has historically played an important role in detection of cardiovascular disease as well as in risk stratification and prognostication. With the growth of molecular biology have come new therapeutic interventions and the requirement for new diagnostic imaging approaches. Noninvasive targeted...

journal_title：Current cardiology reports

authors： Dobrucki LW,Sinusas AJ

更新日期：2005-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Results from cardiovascular (CV) outcome trials have revealed important insights into the CV safety and efficacy of glucose-lowering agents, including dipeptidyl peptidase-4 inhibitors (DPP-4i) and glucagon-like peptide-1 receptor agonists (GLP-1RA). RECENT FINDINGS:Among patients with T2DM, DPP-4i h...

journal_title：Current cardiology reports

authors： Patel KV,Sarraju A,Neeland IJ,McGuire DK

更新日期：2020-08-08 00:00:00

abstract：:Innate differences in gender physiology result in unique exposures, risk, and protection that are specific to women. Recognition and appreciation of these differences results in better treatment adaptations for women and better outcomes. Disparities between genders in the treatment of major cardiovascular risk factors...

journal_title：Current cardiology reports

authors： Jarvie JL,Foody JM

更新日期：2010-11-01 00:00:00

abstract：PURPOSE OF REVIEW:To establish the actual role of CT in the growing field of transcatheter valve interventions (THV). RECENT FINDINGS:The development of empirical CT measurements, which are linked with outcomes. CT is a reliable technique for assessing risk and planning transcatheter valve interventions for mitral and...

journal_title：Current cardiology reports

authors： Godoy M,Mugharbil A,Anastasius M,Leipsic J

更新日期：2019-11-25 00:00:00

abstract：:The risk of stroke associated with carotid artery stenosis can be reduced with carotid endarterectomy or carotid artery stenting in carefully selected patients. While surgery has been the traditional treatment there have been many trials comparing carotid endarterectomy with carotid artery stenting, and stenting has s...

journal_title：Current cardiology reports

authors： Buschur M,Gurm HS

更新日期：2012-02-05 00:00:00

abstract：PURPOSE OF REVIEW:This review provides an update on rheumatic mitral stenosis. Acute rheumatic fever (RF), the sequela of group A β-hemolytic streptococcal infection, is the major etiology for mitral stenosis (MS). RECENT FINDINGS:While the incidence of acute RF in the Western world had substantially declined over the...

journal_title：Current cardiology reports

authors： Wunderlich NC,Dalvi B,Ho SY,Küx H,Siegel RJ

更新日期：2019-02-28 00:00:00

abstract：PURPOSE OF REVIEW:Transcatheter aortic valve replacement (TAVR) has developed into an important alternative to surgical aortic valve replacement (SAVR) for patients with severe aortic stenosis (AS). Adjuvant antithrombotic therapies are commonly used during and after TAVR to decrease the risk of valve thrombosis and th...

journal_title：Current cardiology reports

authors： O'Malley RG,Mahaffey KW,Fearon WF

更新日期：2017-05-01 00:00:00

abstract：PURPOSE OF REVIEW:To summarize lifestyle interventions including pharmacological and non-pharmacological methods targeting modifiable risk factors and their impact on the future cardiovascular events in patients who have suffered transient ischemic attack (TIA) and/or ischemic stroke (IS). RECENT FINDINGS:The latest r...

journal_title：Current cardiology reports

authors： Vellipuram AR,Rodriguez G,Rawla P,Maud A,Cruz-Flores S,Khatri R

更新日期：2019-04-22 00:00:00

abstract：PURPOSE OF REVIEW:To describe lipid abnormalities in diabetes, when they occur and the evidence base for lipid management with established and new drugs to prevent diabetes complications. We also discuss how to manage statin intolerance. RECENT FINDINGS:Statins remain first-line therapy in patients with diabetes, thou...

journal_title：Current cardiology reports

authors： Sillars A,Sattar N

更新日期：2019-11-22 00:00:00